• Journal of Ocean Engineering and Technology
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• v.15 no.3
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• pp.134-141
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• 2001

An experimental method to investigate the dynamic characteristics of buoys in extreme environmental condition is established. Because the buoy model requires a resonable size for accurate experiment, the test condition in model basin that satisfies the similarity law is hardly compatible with capability of test facilities. It is suggested that the linear wave component that is unable to satisfy similarity is separated with others. The model experiment is carried out with mitigated condition for the linear wave components while others including wave drift, current and wind are keeping the similarities. Then, the result can be extrapolated to give the dynamic behavior of buoys n extreme condition because linear wave component is solely responsibly to oscillatory buoy motion and other environmental components are applied as a initial tension. The similarity for current and wind conditions is viewed as equivalence of restoring forces. The validity of proposed method is examined with different types of standard ocean buoys and it indicates that the linearity of measured characteristics is assured with a limitation of resonable distance between test and estimated wave conditions.

• Proceedings of the KIEE Conference
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• 1999.11d
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• pp.978-980
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• 1999

In this paper, DC degradation of ZnO varistor sintered in the atmospheres of nitrogen and oxygen was investigated. The content of $SiO_2$ containing 0.0, 0.2, 0.5 mol% respectively was addicted for the improvement of degradation property. ZnO varistor was fabricated in the special electrical furnace which had the vacuum system. The temperature and the voltage for the DC degradation test were $115{\pm}2^{\circ}C$, $0.85V_{1mA/cm^2}$. The time conditions for this test were 0, 2, 4, 8 hours and Current-voltage analysis is used to determine nonlinear coefficients($\alpha$). Frequency analysis are accomplished for the understanding of electrical properties as DC degradation test. In this experiment, We concluded that nonlinear coefficient decreased as the amount of $SiO_2$ addition increased, but degradation rate coefficient increased as the amount of $SiO_2$ addition increased. Also, degradation test with the analysis of equivalent circuit showed that the degradation phenomenon of ZnO varistor wasn't linearity.

• Biomolecules & Therapeutics
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• v.16 no.1
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• pp.61-68
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• 2008

In order to develop an improved paclitaxel formulation vehicle, a micelle forming solubilizer, Aceporol 330 was synthesized. It was previously reported that Aceporol 330 provided the linearity of paclitaxel plasma pharmacokinetics. In this study, the single dose toxicity test and 2-week repeated dose toxicity test of Aceporol 330 was performed in beagle dogs after intravenous administration. Single dose and 2-week repeated dose toxicity test of Aceporol 330 showed fever/generalized erythema, severe vomiting, and diarrhea in beagle dogs. However, those toxicities were less severe than those of Cremophor EL. Blood chemistry analysis of 2-week repeatedly treated beagle dogs with Aceporol 330 showed significant elevation of total cholesterol (TCHO) and triglyceride (TG) compared to that of control group. Cremophor EL also significantly increased total cholesterol (TCHO) and triglyceride (TG) as much as Aceporol 330. Results from this study indicated that Aceporol 330 was less toxic than Cremophor EL. Based on the pharmacokinetic advantages and the low toxicity of Aceporol 330 in single dose and 2-week repeated dose toxicity test, Aceporol 330 has a potential for use as a safer solubilizer for paclitaxel than Cremophor EL.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2001.05a
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• pp.208-215
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• 2001

An experimental method to investigate the dynamic charasteristics of buoys in extreme environmental condition is established. Because the buoy model requires a resonable size for accurate experiment, the test condition in model basin that satisfies the similarity law is hardly met with capability of test facilities. It is suggested that the linear wave component that is unable to satisy similarity is separated with others. The model experiment can be carried out with mitigated condition for the linear wave components while others including wave drift, current and wind are keeping the similarities. Then the result is extrapolated to give the dynamic behavior of buoys in extreme condition because linear wave component is soley responsible to oscillatory buoy motion and other environmental components are applied as a initial tension. the similarity for current and wind conditions is viewed as equivalence of restoring forces. the validity of proposed method is examined with different types of standard ocean buoys and it indicates that the linearity of measured characteristics is assured with a limitation of resonable distance between test and estimated wave conditions.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.2
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• pp.667-673
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• 2021

This causal quantitative research aims to investigate the influence of factors that determine the performance of employees in Indonesian universities. The factors are crucial for organizations in the achievement of their goals. Based on theoretical studies, three independent variables, namely, training, personality, and work motivation were tested for their influence on employee performance, which was the dependent variable. Primary data were obtained from 94 respondents of a total population of 122 individuals at the Education Quality Assurance Institute (LPMP) in Banten Province, Indonesia. They were tested by the normality test using the Kolmogorov-Smirnov approach to ensure their normally distributed population and the linearity test to measure the significant linear relationship between the two variables. There are five hypotheses in this study. Each hypothesis tested by the F-test to determine the significant effect of all independent variables on the dependent variable, and t-test to analyze the effect. The results of this study answered all hypotheses of the research model. There is a positive direct effect of training and personality on work motivation. Both training and personality also affect positively employee performance. Another finding of this study is that employee performance is positively and directly affected by work motivation.

• The Korean Journal of Nuclear Medicine Technology
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• v.26 no.1
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• pp.38-41
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• 2022

Purpose Testosterone is a steroid hormone synthesized by the Leydig cells of the testes in men, and by the adrenal cortex and ovaries in women. Testosterone production is regulated by luteinzing hormone secreted by the anterior pituitary gland. In this experiment, the effectiveness of testosterone radioimmunoassay (RIA) kits produced by three companies was evaluated and compared in case the production of testosterone kits was stopped or supply problems occurred. Materials and Methods In October 2021, samples were collected from the patients (n=49) who requested the testosterone RIA test. The experiment was conducted by dividing the patient's sample into low concentration (1.0 ng/mL or less), medium concentration (2.0-4.0 ng/mL) and high concentration (6.0 ng/mL or more). The Testosterone RIA test compared and evaluated the validity of Company A kits used in this hospital and those of Company B and C used in other hospitals. The precision, sensitivity, recovery, linearity and correlation were evaluated for each kit. The testosterone RIA test was carried out in accordance with the insert kit manual for each manufacturer. Results As a result of measuring the precision of the intra assay, the Coefficient of Variation (CV) value of the company A kit was high at 11.4% only in the low concentration sample, and in the case of the company B and C kits, the CV value was less than 10% at low, medium, and high concentrations. In the inter-assay precision measurement, the CV value was less than 15% in both A and C kits, but in the case of the B kit, the CV value exceeded 15% at low and medium concentrations. Sensitivity was 0.13 ng/mL for company A, 0.01 ng/mL for company B, and 0.01 ng/mL for company C, and the linearity of all three kits showed excellent linearity. In the case of recovery rate, all of the A, B, and C company kits showed results that were out of 90-110%. In the case of correlation test, when compared with the company A kit currently use in here, the correlation coefficient (R²) value for the company B kit was 0.9508, and for the company C kit was 0.9352 Conclusion As a result, there was a slight difference in precision at the low concentration sample. The correlation test showed an excellent correlation coefficient. However, it was difficult to secure samples of various concentrations because there were not many tests of testosterone requested at this hospital. So, additional experiments should be carried out by acquiring samples of various concentrations on each laboratory later.

• Journal of Food Hygiene and Safety
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• v.31 no.5
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• pp.311-318
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• 2016

Azorubine is a synthetic tar color containing azo-bond in the molecular structure. This food colorant has been allowed to be used for beverages, cheese and dried fruits in the European Union and for some food in Australia. Even though it is applicable as a food color in many countries, this compound has not been permitted in Korea so far as a food additive. Thus, this study was performed to establish an analysis method for azorubine in Korea by comparison of three HPLC analysis methods for azorubine and other azo-compounds which are officially used in the European Food Safety Authority (EFSA, EU), the Food Standard Agency (FSA, England) and the National Institute of Food and Drug Safety Evaluation (NIFDS, Korea). The analysis method of the FSA for azorubine showed the best linearity ($r^2=0.999$), limit of detection (LOD, $0.07{\mu}g/mL$), limit of quantification (LOQ, $0.20{\mu}g/mL$), precision (0~0.5%) and accuracy (98.6~100.7%) among tested HPLC methods using a C-18 column and diode array detector (DAD) with ammonium acetate solution and acetonitrile as an eluent solution. Finally selected method of FSA was further verified by inter-day and intra-day experiments with linearity, LOD, LOQ, precision and accuracy. Recovery test showed the recover ratios of 97~103%, 95~101%, and 93~102% in beverages, breads/snacks and other foods, respectively. Inter-laboratory test represented the absolute value of z-score of less than 2 which means satisfactory levels in this test. Selected method of FSA showed reliable analytical results in application test using food samples collected in commercial markets in Europe.

• Journal of the Korea institute for structural maintenance and inspection
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• v.8 no.1
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• pp.183-194
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• 2004

It's essential process to study non-linear material function related to characteristics of compressibility and permeability when we predict the consolidation behavior of soft clay ground. In this study, laboratory tests were conducted to find out the material function using marine clay. Standard oedometer test and Rowe cell test were performed with conditions, which were classified into vertical drainage only, radial drainage only and vertical-radial drainage case. Modified oedometer test equipment was developed to find out the material function and special extrusion device was originated to minimize the sample disturbance effect. Reliability of the results in modified oedometer test could be confirmed by comparing with the Rowe cell's one. Effective stress - void ratio - permeability relations were analyzed using all testing results. As a result, void ratio with effective stress level could be expressed by the power function and permeability with void ratio could be expressed by exponential function. In soft clay with high initial water content and low shear strength, non-linear characteristics related to compressibility and permeability varied with wide range by the effective stress levels. It's important to note that non-linearity of the material function should be considered at prediction of the consolidation behavior.

• Journal of the Korean GEO-environmental Society
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• v.19 no.12
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• pp.47-58
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• 2018

Duncan & Chang(1970) proposed the Duncan-Chang model that a linear relation of transformed stress-strain plots was reconstituted from a nonlinear relation of stress-strain curve of triaxial compression test using hyperbolic theory so as to estimate an initial tangent modulus and ultimate deviator stress for the soil specimen. Although the transformed stress-strain plots show a linear relationship theoretically, they actually show a nonlinearity at both low and high values of strain of the test. This phenomenon indicates that the stress-strain curve is not a complete form of a hyperbola. So, if linear regression analyses for the transformed stress-strain plot are performed over a full range of strain of a test, error in the estimation of their linear equations is unavoidable depending on ranges of strain with non-linearity. In order to reduce such an error, a modified regression analysis method is proposed in this study, in which linear regression analyses for transformed stress-strain plots are performed over the entire range of strain except the range the non-linearity is shown around starting and ending of the test, and then the initial tangent modulus and ultimate deviator stresses are calculated. Isotropically consolidated-drained triaxial compression tests were performed on compacted weathered soil with a modified Proctor density to obtain their model parameters. The modified regression analyses for transformed stress-strain plots were performed and analyzed results are compared with results estimated by 2 points method (Duncan et al., 1980). As a result of analyses, initial tangent moduli are about 4.0% higher and ultimate deviator stresses are about 2.9% lower than those values estimated by Duncan's 2 points method.

• Herbal Formula Science
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• v.19 no.1
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• pp.183-194
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• 2011

Objectives : To estimate the shelf-life by long-term storage test of Pyungwi-san. Methods : Experiments were conducted to evaluate the stability such as the selected physicochemical, heavy metal, microbilogical experiment under an acceleration test and long-term storage test of Pyungwi-san in different storage under room temperature, refrigeration and freezing. Futhermore, HPLC analysis was performed for the determinations of glycyrrhizin in the Pyungwi-san on an Inertsil ODS-3 column(250 mm ${\times}$ 4.6 mm, 5 um) using solvent 35% acetonitrile include 0.05% phosphoric acid at 254 nm. The flow rate was 1.0 mL/min. Results : The significant change was not showed in pH, heavy metal, microbiological, identification test and quantitative analysis based on acceleration test and long-term storage test. Retention time of glycyrrhizin in HPLC chromatogram was about 16.065 min and calibration curve showed good linearity($R^2$ = 0.9999). The contents of glycyrrhizin in acceleration test and long-term storage test were 0.068~0.076 mg/mL and 0.066~0.077 mg/mL, respectively. Shelf-lifes of room temperature, refrigeration and freezing by long-term storage test were predicted 41, 24 and 34 months, respectively. Conclusions : The suggested shelf-life would be helpful on the storage and distribution of herbal medicine.