• Bulletin of the Korean Chemical Society
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• v.35 no.8
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• pp.2375-2380
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• 2014

In the present investigation, a series of some novel 1,3-diaryl/heteroarylprop-2-en-1-one derivatives (3a-j) have been synthesized and evaluated for their in vitro cytotoxicity against three cancer cell lines, two hepatocarcinoma cell lines HUH-7, Hep-3b and one leukemia cancer cell line MOLT-4. Based on these results, structure-activity relationship (SAR) was studied on modification of $R^1$ and $R^2$ to identify the compound with maximum potency. Amongst the compounds, 3b and 3d strongly inhibited the growth of Hep-3b and MOLT-4 cells with $IC_{50}$ value of 3.39 and $3.63{\mu}M$ respectively. The results obtained from the inhibitory study had further been supported by the reactive oxygen species (ROS) measurement using flow cytometry in MOLT-4 cells. These observations collectively reveal that compounds comprising 1,3-diarylprop-2-en-1-one framework with pyrazole ring at position-3 and heteroaryl/aryl substituents at position-1 can be used as promising anticancer agents.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.24 no.1
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• pp.130-134
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• 2015

The automobile industry is ubiquitous and involved in the handling of metal, machines, electricity, electron, and chemistry including the products of many types of processes. In the process of installing engines as a part of the car assembly line, the measurement and correction of the position of the stud bolts consumes a great deal of time. Additionally, defective parts must be manually removed. In the process of engine installation, the speed of the operation, related to the economics of vehicle assembly, is dependent upon measuring the precise position of the stud bolt, reducing the length of correction time, and increasing the working rate. This paper deals with securing the economic feasibility of the manufacturing process, increasing the safety by removing risk factors in the working area, and improving and equalizing the quality by developing an automatic system for the process involving a stud bolt.

• Journal of the Korea Institute of Military Science and Technology
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• v.20 no.6
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• pp.774-780
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• 2017

The techniques for driving trajectory calculation and driving trajectory distribution calculation are proposed to analyze the durability of ground vehicles effectively. To achieve this aim, the driving trajectory of a vehicle and the driving trajectory distribution of that are needed, in addition to road profile. The road profiles can be measured by a profilometer but a driving trajectory of a vehicle cannot be acquired effectively due to a large position error from a conventional GPS sensor. Therefore two techniques are proposed to reduce the position error of a vehicle and achieve the distribution of driving trajectory of that. The driving trajectory calculation technique produces relative positions by using the velocity, time and heading of a vehicle. The driving trajectory distribution calculation technique produces distributions of the driving trajectory by using axis transformation, estimating reference line, dividing sectors and plotting a histogram of the sectors. As a results of this study, we can achieve the considerably accurate driving trajectory and driving trajectory distribution of a vehicle.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.20 no.2
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• pp.101-106
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• 2021

In this paper, an inspection system has been developed where pneumatic instruments are used to stretch the film using compressed air, thus the curl problem can be overcome. When the pneumatic system is applied, a line scan camera should be used instead of an area camera because the COF surface makes an arc by the air pressure. The distance between the COF and the inspection camera should be kept constant to get a clear image, thus the position of COF is to be monitored on real-time. An operating software has been also developed which is switching on/off the pneumatic system, determining the COF position using a camera vision, displaying the contour of the COF side view, sending self-diagnosis result and etc. The developed system has been examined using the actual roll of COF, which convince that the system can be an effective device to inspect the COF rolls in process.

• Journal of the Korean Society of Safety
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• v.37 no.4
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• pp.58-62
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• 2022

Metro subway construction is a field that requires a great deal of professional manpower. The aging of professionals has a negative impact on both productivity and health, owing to poor working environments, heavy lifting, underground work, and other factors. To address this issue, the government is progressively revising and enforcing health management law and regulation in the construction industry. Thus, the job stress and work ability of many professional subway construction workers, who are rapidly aging, are being analyzed to ensure their safety and improve their health. In this study, the Macpa stress index of Busan Metro Subway construction workers from Sasang to Hadan line was measured by using a Macpa measurement machine, and a work ability survey was conducted by using the questionnaire that was developed by the FIOH. The independent variables were age, years of service, job position, employment type, and occupation. While, the dependent variables were the Macpa stress index and work ability. The Kruskal-Wallis test was used because it was difficult to assume that the statistics of this study represented a normal distribution. The results showed that age, job position, and employment type affected Macpa stress index and revealed that as the age of the workers increased, their stress levels increased as well. Additionally, job position and employment type affected the work ability of the metro subway construction workers. In terms of job position, the technical engineers were under a lot of stress, and whereas the managers had the best work ability. The technical engineers were more stressed than the other workers because of a poor working environment. In terms of employment type, daily workers were under more stress and lower work ability than others.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.14 no.5
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• pp.73-79
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• 2014

In this paper, we proposed the mechanism which can measure traffic flow and vehicle speed on the highway as well as road by using the video and image processing to detect and track cars in a video sequence. The proposed mechanism uses the first few frames of the video stream to estimate the background image. The visual tracking system is a simple algorithm based on the sum of absolute frame difference. It subtracts the background from each video frame to produce foreground images. By thresholding and performing morphological closing on each foreground image, the proposed mechanism produces binary feature images, which are shown in the threshold window. By measuring the distance between the "first white line" mark and the "second white line"mark proceeding, it is possible to find the car's position. Average velocity is defined as the change in position of an object divided by the time over which the change takes place. The results of proposed mechanism agree well with the measured data, and view the results in real time.

• Journal of Oral Medicine and Pain
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• v.24 no.2
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• pp.189-206
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• 1999

This study was performed to investigate the factors affecting muscle activity and cephalometric variables according to change of head postures. For this study, 150 patients with temporomandibular disorders and 80 dental students without any signs and symptoms of temporomandibular disorders were selected as the patients group and as the normal group, respectively. Head position to body-midline in frontal plane and upper quarter posture to body plumb line in sagittal plane were observed clinically and electromyographic(EMG) activity of anterior temporalis, masseter, sternocleidomastoideus, and trapezius on clenching were recorded with $BioEMG^{(R)}$ in four head postures, which were natural head posture(NHP), forward head posture(FHP), $20^{\circ}$ upward head posture(UHP), and $20^{\circ}$ downward head posture(DHP). Cephaloradiographs were also taken in the same head postures as in EMG taking, but that was taken only in NHP for the patient group. Cephalometric variables measured were SN angle, CVT angle, atlas inclination angle, occlusal plane angle, Me-C2 angle, pharyngeal width, occiput~axis distance, area of pharyngeal space, and cervical curvature. The data were analyzed by SAS statistical program. The results of this study were as follows : 1. Between the patient and the normal group, there were significant difference in distance from plumb line to acromion, eye-tragus angle, electromyographic activity of the four muscles, and cephalometric variables of linear measurement. 2. There was no consistent pattern of correlation between upper quarter posture, EMG activity and cephalometric variables in any case without relation to cervical curvature and head position in frontal plane. 3. Sternocleidomastoid muscle only showed variation of electromyographic activty with changes of head postures, but all the muscles did show correlation with head postures. 4. All the cephalometric variables measured in this study showed difference of mean value by head posture, and CVT angle, pharyngeal width, occiput-atlas distance, and area of pharyngeal space showed correlation between these variables with change from NHP to FHP, and from NHP to UHP.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.33 no.6
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• pp.643-647
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• 2007

Purpose: The purpose of study was to investigate the correlationship between lip canting change and occlusal canting change after bimaxillary orthognathic surgery, and the ratio of lip canting change and occlusal canting change after the surgery. Patients and methods: The subjects for this study was obtained from a group of 25 patients who took bimaxillary orthognathic surgery for occlusal canting correction at the Department of the Oral and Maxillofacial Surgery, Samsung Medical Center in Seoul, Korea between January 2000 and December 2005 and a patient's chart had to contain a resting frontal facial photograph in natural head position and a corresponding PA cephalogram in occlusion on the same day before the surgery and post-op 6 months later. The lip canting change was assessed with the angle each labial commissure and the bipupilary reference line. And, the occlusal caning change in the frontal plane was assessed with the angle between the each maxillary first molar occulasal surface and the bi-frontozygomatic suture reference line. Results: In angular measurement, average occlusal canting change was $3.09^{\circ}$ and standard deviation was $1.05^{\circ}$, average lip canting change was $1.56^{\circ}$ and standard deviation was $1.05^{\circ}$. In linear measurement, average occlusal canting change was 2.41mm and standard deviation was 2.75mm, average lip canting change was 1.18mm and standard deviation was 0.43mm. Lip canting correction ration to occlusal canting correction was 51.5(${\pm}8.4$)% in angular measurement and 48.8(${\pm}9.1$)% in linear measurement. Under Pearson's correlation analysis, Pearson's correlation coefficient was 0.869 in angular measurement and 0.887 in linear measurement(p-value < 0.01). High correlationship was shown between occlusal canting change and lip canting change. Conclusion: First, Bimaxillary orthognathic surgery can correct lip canting as well as occlusal canting. Second, The average amount of lip canting correction is $51.5{\pm}8.4%,\;48.8{\pm}9.1%$ of occlusal canting correction in the study.

• Journal of Institute of Control, Robotics and Systems
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• v.21 no.2
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• pp.81-86
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• 2015

GPS position errors were corrected for guidance of autonomous vehicles. From the vision, we can obtain the lateral distance from the center of lane and the angle difference between the left and right detected line. By using a controller which makes these two measurements zero, a lane following system can be easily implemented. However, the problem is that if there's no lane, such as crossroad, the guidance system of autonomous vehicle does not work. In addition, Line detection has problems working on curved areas. In this case, the lateral distance measurement has an error because of a modeling mismatch. For this reason, we propose GPS error correction filter based on curve-modeled lane detection and evaluated the performance applying it to an autonomous vehicle at the test site.

• Membrane and Water Treatment
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• v.4 no.3
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• pp.157-174
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• 2013

The present study is devoted to the validation of a new method for in line electrokinetic characterisation of deposits on membrane surfaces. This method is based upon simultaneous measurements of transversal streaming potential and permeates flux at constant pressure before and during the deposit formation. Dead-end filtration experiments were conducted with negative flat membranes forming a narrow slit channel, negative hollow fiber membranes and mono-dispersed suspensions of (negatively charged) polystyrene latex and (positively charged) melamine particles at various concentrations. It was observed that the overall streaming potential coefficient increased in absolute value with the deposited latex quantity, whereas it decreased and changed of sign during the filtration of melamine suspensions. By considering a resistance-in-series model, the streaming potential coefficient of the single deposit ($SP_d$) was deduced from the electrokinetic and hydraulic measurements. The independence of $SP_d$ with respect to growth kinetics validates the measurement method and the reliability of the proposed procedure for calculating $SP_d$. It was found that $SP_d$ levelled off much more quickly when filtration was performed through the slit channel. This different behaviour could result from a non-uniform distribution of the deposit thickness along the membrane given that the position of measuring electrodes is different between the two cells.