• 천문학회보
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• 제44권1호
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• pp.66.4-66.4
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• 2019

NGC 6822 is a dwarf irregular galaxy whose metal abundance is lower than of the Large Magellanic Cloud. Hubble V is the brightest HII complex where molecular clouds surround the core cluster of OB stars. Because of its proximity (d = 500 kpc), we can resolve the star-forming regions on parsec scales (1 arcsec = 2.4 pc). Using the high-resolution (R = 45,000) near-infrared spectrograph, IGRINS, we observed molecular hydrogen emission lines from photo-dissociation regions (PDRs) and $Br{\gamma}$ emission line from ionized regions. In this presentation, we compare our data PDR models in order to derive the density distribution of the molecular clouds on parsec scales and to estimate the total mass of the clouds.

• Communications for Statistical Applications and Methods
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• 제28권5호
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• pp.477-491
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• 2021

The Markov modulated Brownian motion is a substantial generalization of the classical Brownian Motion. On the other hand, the Markovian arrival process (MAP) is a point process whose family is dense for any stochastic point process and is used to approximate complex stochastic counting processes. In this paper, we consider a superposition of the Markov modulated Brownian motion (MMBM) and the Markovian arrival process of jumps which are distributed as the bilateral ph-type distribution, the class of which is also dense in the space of distribution functions defined on the whole real line. In the model, we assume that the inter-arrival times of the MAP depend on the underlying Markov process of the MMBM. One of the subjects of this paper is introducing how to obtain the first passage probabilities of the superposed process using a stochastic doubling algorithm designed for getting the minimal solution of a nonsymmetric algebraic Riccatti equation. The other is to provide eigenvalue and eigenvector results on the superposed process to make it possible to apply the GTH-like algorithm, which improves the accuracy of the doubling algorithm.

• 영어영문학
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• 제64권1호
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• pp.77-94
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• 2018

This paper examines William and Ellen Craft's Running a Thousand Miles for Freedom (1860)-a narrative of the enslaved couple's escape from Macon to Philadelphia in the guise of a white male master and a colored slave. Expanding Judith Adler's notion of "travel as performed art," my reading of Running focuses on the Crafts' stratagems of transvestism-crossing boundaries not only of gender, but also of race, class, and disability. If travel can be understood as a form of performed art, then why not address a traveler as a performance artist? I present William and Ellen's role-playing in Running as performers of crossing borders and categories, or, as "fugitive performers," since the couple's story never reaches its final arrival but narrates an eternal run-away, far more than "a thousand miles to freedom." Using social stereotypes of race and gender to disguise, William and Ellen plot, write, choreograph, play, and recite on the moving stages and manipulate the others-especially white American audiences-who accompany the couple's run-away and those who were responsible for the cultural drama-a tragedy of American slavery. Becoming "fugitive performers," William and Ellen de-essentialize and debunk the nineteenth-century America's firm belief in distinct color line between black and white, and in the high yet unstable bars between male / female, abled / disabled, master / slave, and freedom / slavery. The Crafts alert their contemporaries and readers by presenting the complex and permeable boundaries of race, gender, class, social and cultural ability.

• Journal of Microbiology and Biotechnology
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• 제30권12호
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• pp.1810-1818
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• 2020

Inhibitor K562 (IK) protein was first isolated from the culture medium of K562 cells, a leukemia cell line, and is an inhibitory regulator of interferon-γ-induced major histocompatibility complex class II expression. Recently, exogenous truncated IK (tIK) protein showed potential as a therapeutic agent for inflammation-related diseases. In this study, we designed a novel putative anti-inflammatory peptide derived from tIK protein based on homology modeling of the human interleukin-10 (hIL-10) structure, and investigated whether the peptide exerted inhibitory effects against pro-inflammatory cytokines such as IL-17 and tumor necrosis factor-α (TNF-α). The peptide contains key residues involved in binding hIL-10 to the IL-10 receptor, and exerted strong inhibitory effects on IL-17 (43.8%) and TNF-α (50.7%). In addition, we used circular dichroism spectroscopy to confirm that the peptide is usually present in a random coil configuration in aqueous solution. In terms of toxicity, the peptide was found to be biologically safe. The mechanisms by which the short peptide derived from human tIK protein exerts inhibitory effects against IL-17 and TNF-α should be explored further. We also evaluated the feasibility of using this novel peptide in skincare products.

• Tribology and Lubricants
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• 제37권1호
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• pp.1-6
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• 2021

This paper presents the experimental results of hydrophobic surfaces developed using a stereolithography-based additive-manufacturing technique. The additive manufacturing technique can be used to manufacture objects with complex geometries from computer-aided design data. Several additive manufacturing methods, such as selective laser sintering, fused deposition modeling, stereolithography apparatus (SLA), and inkjet-based system, have been developed. The SLA is a form of three-dimensional printing technology used to create prototypes, patterns, and production parts in successive layers through photochemical processes. Light causes chemical monomers and oligomers to cross-link together to form objects composed of polymers. Moreover, this method is economical for fabricating surfaces with high output resolution and quality. Here, we fabricate various surfaces using different shapes using an SLA. The surfaces with micro-patterns are fabricated for 10 cases, including the biomimetic surface. The fabricated surfaces with various micro-patterns are evaluated for hydrophobicity performance based on the static contact angle. The contact angle is measured three times for each case, and the averaged value is used. The results indicate that the arrangements in a staggered structure have a larger contact angle than those in a line when the same micro-pattern is applied. Moreover, the mimetic surfaces exhibit more hydrophobic characteristics than those of artificial micro-patterns.

• Structural Engineering and Mechanics
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• 제77권5호
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• pp.613-626
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• 2021

In this paper, an enhanced Violation-based Sensitivity analysis and Border-Line Adaptive Sliding Technique (ViS-BLAST) will be utilized for optimization of some well-known structural and mechanical engineering problems. ViS-BLAST has already been introduced by the authors for solving truss optimization problems. For those problems, this method showed a satisfactory enactment both in speed and efficiency. The Enriched ViS-BLAST or EVB is introduced to be vastly applicable to any solvable constrained optimization problem without any specific initialization. It uses one-directional step-wise searching technique and mostly limits exploration to the vicinity of FNF border and does not explore the entire design space. It first enters the feasible region very quickly and keeps the feasibility of solutions. For doing this important, EVB groups variables for specifying the desired searching directions in order to moving toward best solutions out or inside feasible domains. EVB was employed for solving seven numerical engineering design problems. Results show that for problems with tiny or even complex feasible regions with a larger number of highly non-linear constraints, EVB has a better performance compared to some records in the literature. This dominance was evaluated in terms of the feasibility of solutions, the quality of optimum objective values found and the total number of function evaluations performed.

• International Journal of Computer Science & Network Security
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• 제22권5호
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• pp.215-219
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• 2022

Bankruptcy is one of the major areas that have attracted the interest of many researchers in the American system, particularly in terms of the laws that oversee it. It provides a plan of reorganization that enables the debtor or the proprietor to discharge liabilities to the creditors through dividing the assets to settle debts. This activity is carried out under supervision to fairly protect the interests of the creditors. Bankruptcy protection systems are dynamic and complex in nature, in line with the economic sector, ensuring the protection of affected individuals from falling into huge losses. Some bankruptcy procedures give the debtor the opportunity to stay in operation or business activity and benefit from revenues until the debt is settled. This law allows some debtors to be relived from any financial burden after the distribution of assets, even if the debt is not paid in full. In light of the above information, this research paper seeks to explore the nature of the complexity of bankruptcy protection laws, their characteristics, and the justice system that regulate them. It also sheds more light on the decision-making powers on bankruptcy cases. There are specialized courts that cover bankruptcy cases located in district courts in every state.

• Biomolecules & Therapeutics
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• 제31권3호
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• pp.340-349
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• 2023

Mad2B (Mad2L2), the human homolog of the yeast Rev7 protein, is a regulatory subunit of DNA polymerase ζ that shares sequence similarity with the mitotic checkpoint protein Mad2A. Previous studies on Mad2B have concluded that it is a mitotic checkpoint protein that functions by inhibiting the anaphase-promoting complex/cyclosome (APC/C). Here, we demonstrate that Mad2B is activated in response to cisplatin-induced DNA damage. Mad2B co-localizes at nuclear foci with DNA damage markers, such as proliferating cell nuclear antigen and gamma histone H2AX (γ-H2AX), following cisplatin-induced DNA damage. However, unlike Mad2A, the binding of Mad2B to Cdc20 does not inhibit the activity of APC/C in vitro. In contrast to Mad2A, Mad2B does not localize to kinetochores or binds to Cdc20 in spindle assembly checkpoint-activated cells. Loss of the Mad2B protein leads to damaged nuclei following cisplatin-induced DNA damage. Mad2B/Rev7 depletion causes the accumulation of damaged nuclei, thereby accelerating apoptosis in human cancer cells in response to cisplatin-induced DNA damage. Therefore, our results suggest that Mad2B may be a critical modulator of DNA damage response.

• 한국시뮬레이션학회논문지
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• 제19권2호
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• pp.107-118
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• 2010

자동차 제조업은 수천 가지의 다른 구성품 또는 부품의 조립이 필요한 복잡한 생산시스템이다. 엔진과 트랜스미션은 자동차의 동력을 담당하는 주요 구성품이다. 엔진의 경우 생산공정이 대부분 유사한 공정들로 구성되어 있음에도 불구하고 공장별로 생산시스템의 배치안은 상이하다. 그 이유는 각 공장마다 기계들을 어떠한 직렬구조와 병렬구조를 조합하여 배치하는지에 대한 개념이 다르기 때문이다. 이 논문에서는 서로 다른 공장에서 적용하고 있는 세 종류의 엔진 라인을 소개한다. 그리고 시뮬레이션을 이용하여 각 라인의 설계개념이 라인의 성과에 미치는 영향에 대해 비교분석하고자 한다.

• 한국초전도ㆍ저온공학회논문지
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• 제8권3호
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• pp.54-58
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• 2006

In this paper, authors developed a real-time simulation algorithm for the power device application of HTS(High Temperature Superconducting) wire by using Real Time Digital Simulator(RTDS). At present, in order to extend the power capacity of some area where has a serious problem of power quality. especially metropolitan complex city, there are so many problems such as right of way for power line routes. space for downtown substations. and the environmental protection, etc. HTS technology can be useful to overcome this problem. Recently, according to the advanced HTS technology, the power application is being researched well. Simulation is required for safety before installation of HTS power cable, a fabrication model used at the power system simulation. This paper describes a real time digital simulation method for the application of HTS wire to power device. For the simulation analysis, test sample of HTS wire was actually manufactured. And the transient phenomenon of the HTS wire was analysed in the simulated utility power grid. This simulation method is the world first trial in order to obtain much better information for installation of HTS power device into a utility network.