• Proceedings of the KIEE Conference
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• 2004.11b
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• pp.122-124
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• 2004

Recently, power system is getting larger and more complex. When the complex power system has a problem, it is very difficult even for the experts to find out where the problem is and to make a timely decision by operators. There have been many studies on these problems but the results are not good enough for applying to real power system. Therefore power system operators always had to judge the exact state of power system and had to be preparative for the problems that can occur later. We developed new methods that can be applied to complex power system by dividing the system into small modules. By using 'module' we can combine small modules together to make complex power systems and the knowledge base that is applied to fault diagnosis system. As a result, compared to previously developed diagnosis products, operational time has shortened, and the knowledge base becomes simpler and clearer, which made online usage capable. This system can be used as a complementary measure that helps the operator from making any mistakes.

• YAKHAK HOEJI
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• v.44 no.2
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• pp.149-154
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• 2000

Flavin mononucleotide (1,4-butanediamine) Pt(II) complex (7FMN) was synthesized and screened anticancer activity [J. Pharm. Soc. Korea 43(6),762-770 (1999)]. 7FMN have good water solubility and moderate anticancer activiy In this paper cell-cycle specificity and nephrotoxicity were studied. Interaction of DNA with cisplatin and synthesized 7FMN was analyzed by flow cytometry and showed G2 arrest in L1210 cell line. It means that cell-cycle on L1210 was inhibit in S phase by cisplatin and 7FMN. In order to biochemically analyze nephrotoxicity of cisplatin and 7FMN, after injecting each agent intraperitoneally, blood was exsanguinated after 6 hours, 1 day, 3 days and 7 days, respectively. Then, serum was separated from the blood. The serum level of BUN, creatinine and uric acid in cisplatin and 7FMN administated mice (25~35 g, ICR strain, a dose each 8,12 and 16 times of the $IC_{50}$/ value, cisplatin; 7 times) were determined by autochemistry analyzer. In cisplatinadministered mice group, BUN level was elevated than normal control group at 3rd day and repaired at 7th day. In 7FMN administrated group was not elevated. Creatinine and uric acid level were no difference with the normal control group. Therefore synthesized 7FMN is less toxic than cisplatin in nephrotoxiciaty.

• Transactions of Materials Processing
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• v.15 no.6 s.87
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• pp.445-452
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• 2006

In most of automobile body panel manufacturing, trimming process is generally performed before flanging. To find feasible trimming line is crucial in obtaining accurate edge profile after flanging. Section-based method develops blank along manually chosen section planes and find trimming line by generating loop of end points. This method suffers from inaccurate results of edge profile. On the other hand, simulation-based method can produce more accurate trimming line by iterative strategy. In this study, new fast simulation-based method to find feasible trimming line is proposed. Finite element inverse method is used to analyze the flanging process because final shape after flanging can be explicitly defined and most of strain paths are simple in flanging. In utilizing finite element inverse method, the main obstacle is the initial guess generation for general mesh. Robust initial guess generation method is developed to handle genera] mesh with very different size and undercut. The new method develops final triangular mesh incrementally onto the drawing tool surface. Also in order to remedy mesh distortion during development, energy minimization technique is utilized. Trimming line is extracted from the outer boundary after finite element inverse method simulation. This method has many advantages since trimming line can be obtained in the early design stage. The developed method is verified by shrink/stretch flange forming and successfully applied to the complex industrial applications such as door outer flanging process.

• Journal of Korean Tunnelling and Underground Space Association
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• v.7 no.3
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• pp.239-247
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• 2005

A new railway line of about 17km length was planned between Dongbaeksan and the neighboring town Dokye to improve the existing decrepit railway system. New line about 17km of the distance will almost be in circular alignment tunnels owing to the difference of elevation about 380m. Since the geology of the area is rather unusual compared to the normal in South Korea, extensive geological investigations have been carried out to prepare geological maps and profiles along the planned tunnel routes. The tunnel will almost be in sedimentary rock formations, such as limestone, sandstone, shale, coal etc and be near abandoned mines Various rock formations have the complicated, alter ed those rocks, but are well developed with laminated formations. Each rock formations have been classified using the Q-system and the cost of tunnel excavation, support has been estimated and compared for three alternative routes in the design stage. Based on these estimates, the final route of t he railway line was chosen.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2006.11a
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• pp.692-697
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• 2006

The importance about the maintenance consideration of the building has a great impact and regarding the life continuation of the building the many interest is becoming intensively. The housing lot of the heart of urban at the capital region has insufficient recently and the construction of the ground complex building in solution for the insufficiency is increasing at the rapid pace. The ground complex building is brings the maximization of land use from inside the site, but maintenance consideration phase is caused by administration cost share and administration bound limit where person is concerned for a many problem point it contains. The objective of the present paper is that the building is maintain an efficiency initially and is improve in order to develop guide line for a maintenance consideration improvement from design phase. According as literature research and question research is enforce, the paper is escape problem point the maintenance consideration and is bring up guide line for the architectural plan field and the maintenance consideration improvement of the building. Result of the study is expected a help in maintenance consideration improvement during life cycle of the building

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.73-73
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• 1993

As part of a research program to develope 3rd generation anti tumor platinum complexes, a series of platinum complexes which have 4, 5-bis-(aminomethyl)- 1, 3-dioxolane derivatives as bidenate amine ligands, represented by the general structual formula was prepared. The R$_1$ and/or R$_2$ substituents in this series of platinum complexes can be hydrogen. alkyl, of jointly formed cyclohexane. Two Xs can be a bidenate leaving ligand such as 1, 1-cyclobutanedicarboxylate, malonate, dimethylmalonate, ethylmalonate, glycolate, L-lactate, or N-methyliminodiacetate. From based on the pharmacological and toxicological studies, we have chosen SKI 2053R, cis-malonato[(4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-1, 3-dioxolane] platinum(II) complex (NSC D644591) as a candidate for clinical evaluation. The antitumor activity of a new anti tumor platinum complex, cis-malonato [(4R, 5R)-4, 5-bis(aminomethyl)-2-isopropyl-1, 3-dioxolane] platinum(II) (SKI 2053R, NSC D644591), was compared with those of cisplatin and carboplatin using murine tumors. We evaluated three platinum complexes against L1210/CPR, a subline of L1210 leukemia resistant to cisplatin for their abilities to overcome tumor resistance to cisplatin. The in vitro cytotoxicity of SKI 2053R to L1210 cell line was 2.5-fold less potent thann that of cisplatin, and was 10-fold more cytotoxic than that of carboplatin. SKI 2053R retained similar cytotoxic effect and anti tumor activity to L1210/CPR cell line, like the cytotoxicity of SKI 2053R to L1210 cell line, while either cisplatin or carboplatin had not property to overcome the acquired cisplatin-resistance. SKI 2053R exhibited greater or comparable antitumor activity than cisplatin or carboplatin in murine tumor models.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.4D
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• pp.555-561
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• 2009

In lieu of section profile data, a fitting of the bored tunnel shape is more significant confirmation for maintenance of a tunnel. Before the permit on the completion of a tunnel, deformation of the completed tunnel with respect to the design model are considered. And deformation can be produced at continuously along the entire of the tunnel section. This study firstly includes an analysis of algebraic approach and test it with an observed field data. And then a number of methods, line search method, genetic algorithm, and pattern search methods, are compared with the 3D tunnel shape fitting. Algebraic methods can solve a simple circular cylinder type as like a railway tunnel. However, a more complex model (compound circular curve and non circular) as like a highway tunnel has to be solved with soft computing tools in the cause of conditional constraints. The genetic algorithm and pattern search methods are computationally more intensive, but they are more flexible at a complex condition. The line search method is fastest, but it needs a narrow bounds of the initial values.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.54-54
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• 2013

We performed spectroscopic and photometric monitoring observations of a QSO, PG0934+013 for a reverberation-mapping analysis, using the 9-m Southern African Large Telescope (SALT) for spectroscopy and the 2-m Faulkes Telescope North and the South for photometry. The monitoring campaign was carried out for 5 month between December 2012 to April 2013, providing 20 spectroscopic epochs and ~40 photometric epochs. Based on the obtained spectra, which typically have a signal-to-noise ratio to 30-60, we performed multicomponent decomposition using various components, i.e., power-law continuum, FeII emission complex, and broad and narrow emission lines, to properly measure the Hbeta line flux. After a flux normalization using [O III] 5007 line luminosity, we obtained a rms spectrum from all epochs, which shows clear variability of Hbeta line. We find that Hbeta line flux decreases by ~20% during the monitoring period while the continuum flux obtained from the aperture photometry based on the imaging data, shows similar variability. The current Hbeta light curve shows monotonic decrease and a reliable cross correlation analysis between Hbeta and continuum light is difficult. Nevertheless, we obtained a preliminary lag measurements as ~24 light days.

• The Korean Journal of Mycology
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• v.27 no.2 s.89
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• pp.119-123
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• 1999

Genetic diversity of Korean isolates of Pseudomonas tolaasii and WLRO (White line reacting organism) was assessed using BOX-, REP-, and ERIC-PCR analysis. P. tolaasii showed nearly identical band patterns among isolates, whereas considerable DNA polymorphism was found among isolates of WLRO. On the basis of dendogram, WLRO is characterized as a complex group with high degree of genetic differentiation. Genetic relatedness based on repetitive DNA regions was low between P. tolaasii and WLRO isolates.

• The Journal of Korea Robotics Society
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• v.10 no.1
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• pp.9-15
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• 2015

We present a robust power transmission lines detection method based on vanishing point estimation. Vanishing point estimation can be helpful to detect power transmission lines because parallel lines converge on the vanishing point in a projected 2D image. However, it is not easy to estimate the vanishing point correctly in an image with complex background. Thus, we first propose a vanishing point estimation method on power transmission lines by using a probabilistic voting procedure based on intersection points of line segments. In images obtained by our system, power transmission lines are located in a fan-shaped area centered on this estimated vanishing point, and therefore we select the line segments that converge to the estimated vanishing point as candidate line segments for power transmission lines only in this fan-shaped area. Finally, we detect the power transmission lines from these candidate line segments. Experimental results show that the proposed method is robust to noise and efficient to detect power transmission lines.