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Treatment of Refractory Chylous Ascites with an Innovative Peritoneovenous Shunt: Temporary Usage of a Continuous Renal Replacement System: A Case Report

  • Park, Jiyoun;Lee, Jae Jun;Lee, Jung Hee;Shim, Young Mog
    • Journal of Chest Surgery
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    • v.55 no.1
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    • pp.81-84
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    • 2022
  • Esophagectomy and esophageal reconstruction are commonly chosen as surgical options for esophageal cancer. However, prolonged untreated chyle leakage is associated with a poor prognosis. We report the case of a patient with refractory chylous ascites. To limit the ongoing fluid loss, we utilized the chylous ascites as an additional fluid source in a renal replacement therapy system. A continuous renal replacement therapy (CRRT) drainage system was modified to drain both the chylous ascites and venous blood. The ascites drainage rate was determined empirically and regulated by a dial-flow extension set. The CRRT mode was set to continuous venovenous hemodiafiltration and maintained for 7 days. After the patient was weaned from CRRT, ascites did not reaccumulate, and the patient's general condition improved dramatically. No infections related to the system occurred. This procedure temporarily alleviates symptoms and provides more time for alternative treatment strategies.

Machine Learning Based State of Health Prediction Algorithm for Batteries Using Entropy Index (엔트로피 지수를 이용한 기계학습 기반의 배터리의 건강 상태 예측 알고리즘)

  • Sangjin, Kim;Hyun-Keun, Lim;Byunghoon, Chang;Sung-Min, Woo
    • Journal of IKEEE
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    • v.26 no.4
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    • pp.531-536
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    • 2022
  • In order to efficeintly manage a battery, it is important to accurately estimate and manage the SOH(State of Health) and RUL(Remaining Useful Life) of the batteries. Even if the batteries are of the same type, the characteristics such as facility capacity and voltage are different, and when the battery for the training model and the battery for prediction through the model are different, there is a limit to measuring the accuracy. In this paper, We proposed the entropy index using voltage distribution and discharge time is generalized, and four batteries are defined as a training set and a test set alternately one by one to predict the health status of batteries through linear regression analysis of machine learning. The proposed method showed a high accuracy of more than 95% using the MAPE(Mean Absolute Percentage Error).

Multi-Sized cumulative Summary Structure Driven Light Weight in Frequent Closed Itemset Mining to Increase High Utility

  • Siva S;Shilpa Chaudhari
    • Journal of information and communication convergence engineering
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    • v.21 no.2
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    • pp.117-129
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    • 2023
  • High-utility itemset mining (HIUM) has emerged as a key data-mining paradigm for object-of-interest identification and recommendation systems that serve as frequent itemset identification tools, product or service recommendation systems, etc. Recently, it has gained widespread attention owing to its increasing role in business intelligence, top-N recommendation, and other enterprise solutions. Despite the increasing significance and the inability to provide swift and more accurate predictions, most at-hand solutions, including frequent itemset mining, HUIM, and high average- and fast high-utility itemset mining, are limited to coping with real-time enterprise demands. Moreover, complex computations and high memory exhaustion limit their scalability as enterprise solutions. To address these limitations, this study proposes a model to extract high-utility frequent closed itemsets based on an improved cumulative summary list structure (CSLFC-HUIM) to reduce an optimal set of candidate items in the search space. Moreover, it employs the lift score as the minimum threshold, called the cumulative utility threshold, to prune the search space optimal set of itemsets in a nested-list structure that improves computational time, costs, and memory exhaustion. Simulations over different datasets revealed that the proposed CSLFC-HUIM model outperforms other existing methods, such as closed- and frequent closed-HUIM variants, in terms of execution time and memory consumption, making it suitable for different mined items and allied intelligence of business goals.

A Study on the Implementation of Global Medical Budget Model for Hospital based on Sustainablity and Efficiency (지속가능성과 효율성을 고려한 병원 총액예산 설계와 배분에 관한 연구)

  • O, Dongil
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.6
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    • pp.3534-3547
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    • 2014
  • Although there are many positive sides of the current fee-for-service payment schedule, there is a strong necessity to control the rapidly increasing national healthcare expenditure. The global budget is often mentioned as one prominent alternative for solutions. In this article, both microscopic and macroscopic approaches are considered to set the hospital medical expenditure budget. In a macroscopic aspect, the SGR model, which considers the financial limit of the healthcare system, is used to set the next year target budget. In addition, the DEA model is used to measure the inefficiency and cost recognition. In this article, the national medical target expenditure is distributed to an individual hospital based on the level of efficiency. By combining the SGR and DEA, it will be possible to set a real world applicable target medical expenditure budget model.

A Study on Effects of Software Process Improvement for Competitive Advantage (소프트웨어 프로세스 개선 노력이 국내 SI 업체의 경쟁우위에 미치는 영향에 관한 연구)

  • 김성희;이경아;이주헌
    • Journal of Information Technology Applications and Management
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    • v.9 no.3
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    • pp.113-127
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    • 2002
  • The effort for software process improvement is lately surging its interest though it does not satisfy both developer and receiver In terms of low productivity, quality, delay and increasing cost. According to current research, software process improvement contributes to improvement of productivity, its Duality, reduction of development time and cost, and the prediction of the time limit for delivery, which means software process improvement affects competitive advantage among developers. The latest research is whether the investment for information technology substantially had effect on improvement of productivity. That is, software process improvement and maturity of software industries has influence upon economic efficiency and as a result, it plays an important role in whole industries. This research is that how does software process improvement using CMM (Capability Maturity Model) and SPICE (Software Process Improvement and Capability dEtermination) have a effect on factors of software engineering, and how does it have influence upon competitive advantage among SI firms. For this research, reusability, customizability, participation, and review & inspection are set to independent variable and process flexibility and process predictability are set to mediate Variable. Finally, competitive advantage among SI firms Is set to dependent variable. The targets for survey are laborers who work for SI firms. The result of this research is as follows: 1 ) Reusability, Customizability and participation is not rejected but review and Inspection is rejected in process flexibility which has significant level 0.05. 2) Reusability, Customizability and participation is not rejected but review and inspection Is rejected in process predictability which has significant level 0.05. 3) Process flexibility is not rejected and process predictability Is rejected in the competitive advantage of 51 industries which has significant level 0.05

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A Study on the Stability and Mechanism of Three-Hinge Failure (Three-Hinge 파괴의 메커니즘 및 안정성에 관한 분석)

  • Moon, Joon-Shik;Park, Woo-Jeong
    • Journal of the Korean Geotechnical Society
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    • v.33 no.4
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    • pp.5-15
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    • 2017
  • Three-hinge failure occurs in a jointed rock slope with a joint set parallel with slope and a conjugate joint set. Limit Equilibrium Method (LEM) and Finite Element Method (FEM) which are commonly used for slope design, are not suitable for evaluating stability against three-hinge failure, and this study performed parametric study to analyze the failure mechanism and to find influence factors causing three-hinge failure using UDEC which is a commercial two-dimensional DEM based numerical program. Numerical analyses were performed for various joint structural conditions and joint properties as well as ground water conditions. It was found that pore water pressure is the main factor triggering the three-hinge failure and the mode of failure depends on friction angle of basal joint and bedding joint set. The results obtained from this study can be used for adequate and economic footwall slope reinforcement design and construction.

Development of a Multiplex PCR Method to Detect Fungal Pathogens for Quarantine on Exported Cacti

  • Cho, Hyun ji;Hong, Seong Won;Kim, Hyun-ju;Kwak, Youn-Sig
    • The Plant Pathology Journal
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    • v.32 no.1
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    • pp.53-57
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    • 2016
  • Major diseases in grafted cacti have been reported and Fusarium oxysporum, Bipolaris cactivora, Phytophthora spp. and Collectotrichum spp. are known as causal pathogens. These pathogens can lead to plant death after infection. Therefore, some European countries have quarantined imported cacti that are infected with specific fungal pathogens. Consequently, we developed PCR detection methods to identify four quarantined fungal pathogens and reduce export rejection rates of Korean grafted cacti. The pathogen specific primer sets F.oF-F.oR, B.CF-B.CR, P.nF-P.nR, and P.cF-P.CR were tested for F. oxysporum, B.cactivora, P. nicotinae, and P. cactorum, respectively. The F.oF-F.oR primer set was designed from the Fusarium ITS region; the B.CF-B.CR and P.nF-P.nR primers respectively from Bipolaris and Phytophthora ITS1; and the P.cF-P.CR primer set from the Ypt1protein gene region. The quarantine fungal pathogen primer pairs were amplified to the specific number of base pairs in each of the following fungal pathogens: 210-bp (F. oxysporum), 510-bp (B. cactivora), 313-bp (P. nicotinae), and 447-bp (P. cactorum). The detection limit for the mono- and multiplex PCR primer sets was 0.1 ng of template DNA under in vitro conditions. Therefore, each primer set successfully diagnosed contamination of quarantine pathogens in export grafted cacti. Consequently, our methodology is a viable tool to screen contamination of the fungal pathogen in exported grafted cacti.

MALDI-MS-Based Quantitative Analysis of Bioactive Forms of Vitamin D in Biological Samples

  • Ahn, Da-Hee;Kim, Hee-jin;Kim, Seong-Min;Jo, Sung-Hyun;Jeong, Jae-Hyun;Kim, Yun-Gon
    • Korean Chemical Engineering Research
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    • v.58 no.1
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    • pp.106-112
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    • 2020
  • Analyzing vitamin D levels is important for monitoring health conditions because vitamin D deficiency is associated with various diseases such as rickets, osteomalacia, cardiovascular disorders and some cancers. However, vitamin D concentration in the blood is very low with optimal level of 75 nmol/L, making quantitative analysis difficult. The objective of this study was to develop a highly sensitive analysis method for vitamin D using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-MS). 25-hydroxyvitamin D (25(OH)D), which has been used as an indicator of vitamin D metabolites in human biofluids was chemically derivatized using a secosteroid signal enhancing tag (SecoSET) with powerful dienophile and permanent positive charge. The SecoSET-derivatized 25(OH)D provided good linearity (R2 > 0.99) and sensitivity (limit of quantitation: 11.3 fmol). Chemical derivatization of deuterated 25-hydroxyvitamin D3 (d6-25(OH)D3) with SecoSET enabled absolute quantitative analysis using MALDI-MS. The highly sensitive method could be successfully applied into monitoring of quantitative changes of bioactive vitamin D metabolites after treatment with ketoconazole to inhibit 1α-hydroxylase reaction related to vitamin D metabolism in human breast cancer cells. Taken together, we developed a MALDI-MS-based platform that could quantitatively analyze vitamin D metabolites from cell products, blood and other biofluids. This platform may be applied to monitor various diseases associated with vitamin D deficiency such as rickets, osteomalacia and breast cancer.

A Study on 16/32 bit Bi-length Instruction Set Computer 32 bit Micro Processor (16/32비트 길이 명령어를 갖는 32비트 마이크로 프로세서에 관한 연구)

  • Cho, Gyoung-Youn
    • The Transactions of the Korea Information Processing Society
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    • v.7 no.2
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    • pp.520-528
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    • 2000
  • he speed of microprocessor getting faster, the data transfer width between the microprocessor and the memory becomes a critical part to limit the system performance. So the study of the computer architecture with the high code density is cmerged. In this paper, a tentative Bi-Length Instruction Set Computer(BISC) that consists of 16 bit and 32 bit length instructions is proposed as the high code density 32 bit microprocessor architecture. The 32 bit BISC has 16 general purpose registers and two kinds of instructions due to the length of offset and the size of immediate operand. The proposed 32 bit BISC is implemented by FPGA, and all of its functions are tested and verified at 1.8432MHz. And the cross assembler, the cross C/C++ compiler and the instruction simulator of the 32 bit BISC are designed and verified. This paper also proves that the code density of 32 bit BISC is much higher than the one of traditional architecture, it accounts for 130~220% of RISC and 130~140% of CISC. As a consequence, the BISC is suitable for the next generation computer architecture because it needs less data transfer width. And its small memory requirement offers that it could be useful for the embedded microprocessor.

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An Analysis of Visual Fatigue Caused From Distortions in 3D Video Production (3D 영상의 제작 왜곡이 시청 피로도에 미치는 영향 분석)

  • Jang, Hyung-Jun;Kim, Yong-Goo
    • Journal of Broadcast Engineering
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    • v.17 no.1
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    • pp.1-16
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    • 2012
  • In order to improve the workflow of 3D video production, this paper analyzes the visual fatigue caused from distortions in 3D video production stage through a set of subjective visual assessment tests. To establish a set of objective indicators for subjective visual tests, various distortions in production stage are investigated to be categorized into 7 representative visual-fatigue-producing factors, and to conduct visual assessment tests for each selected category, 4 test video clips are produced by combining the extent of camera movement as well as the object(s) movement in the scene. Each produced test video is distorted to reflect each of the selected 7 visual-fatigue-producing factors, and we set 7 levels of distortion for each factor, resulting in 196 5-second-long video clips for testing. Based on these test materials and the recommendation of ITU-R BT.1438, subjective visual assessment tests are conducted by 101 applicants. The test results provide a relative importance and the tolerance limit of each visual-fatigue-producing factor, which corresponds to various distortions in 3D video production field.