• Title/Summary/Keyword: lifetime distributions

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Characteristic Distributions of Hydrogen Peroxide and Methyl Hydroperoxide and over the North Pacific Ocean

  • Lee, Meehye;Brian G. Heikes
    • Journal of Korean Society for Atmospheric Environment
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    • v.18 no.E2
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    • pp.85-95
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    • 2002
  • Hydrogen peroxide and methyl hydroperoxide were measured over the northwestern Pacific Ocean during NASA's PEM (Pacific Exploratory Mission) -West. The first experiment (PEM -West A) was conducted in the fall of 1991 and PEM-West B in the early spring of 1994. Hydroperoxide data were obtained on board the NASA DC -8 aircraft through the entire depth of the troposphere. Average concentrations of both H$_2$O$_2$and CH$_3$OOH were higher during PEM -West A than B. The seasonal difference in hydroperoxide distribution was determined by the degree of photochemical activities and the strength and location of jetstream, which led to extensive and rapid continental outflow during the PEM-West B. While for H$_2$O$_2$distribution, a longitudinal gradient was more apparent than a latitudinal gradient, it was opposite for the CH$_3$OOH distribution. The longitudinal gradient indicates the proximity to the anthropogenic sources from the Asian continent, but the latitudinal gradient reflects photochemical activity. During PEM -West B, the ratio of C$_2$H$_2$/CO, a tracer for continental emission was raised and high concentrations of H$_2$O$_2$were associated with high ratios. The flux of hydroperoxide toward the North Pacific was also enhanced in the early spring. The eastward fluxes of H$_2$O$_2$ were 9% and 17% of the average photochemical production over the Pacific Basin between 140°E and 130°W during PEM-West A and B, respectively. For CH$_3$OOH, these ratios were 8% and 13%. Considering the lifetime of hydroperoxide and the rapid transport of pollutants, the export of hydroperoxide with other oxidants would have a significant influence on oxidant cycles over the North Pacific during winter/spring.

Electrically Driven Quantum Dot/wire/well Hybrid Light-emitting Diodes via GaN Nano-sized Pyramid Structure

  • Go, Yeong-Ho;Kim, Je-Hyeong;Kim, Ryeo-Hwa;Go, Seok-Min;Gwon, Bong-Jun;Kim, Ju-Seong;Kim, Taek;Jo, Yong-Hun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.47-47
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    • 2011
  • There have been numerous efforts to enhance the efficiency of light-emitting diodes (LEDs) by using low dimensional structures such as quantum dots (QDs), wire (QWRs), and wells (QWs). We demonstrate QD/QWR/QW hybrid structured LEDs by using nano-scaled pyramid structures of GaN with ~260 nm height. Photoluminescence (PL) showed three multi-peak spectra centered at around 535 nm, 600 nm, 665 nm for QWs, QWRs, and QDs, respectively. The QD emission survived at room temperature due to carrier localization, whereas the QW emission diminished from 10 K to 300 K. We confirmed that hybrid LEDs had zero-, one-, and two-dimensional behavior from a temperature-dependent time-resolved PL study. The radiative lifetime of the QDs was nearly constant over the temperature, while that of the QWs increased with increasing temperature, due to low dimensional behavior. Cathodoluminescence revealed spatial distributions of InGaN QDs, QWRs, and QWs on the vertices, edges, and sidewalls, respectively. We investigated the blue-shifted electroluminescence with increasing current due to the band-filling effect. The hybrid LEDs provided broad-band spectra with high internal quantum efficiency, and color-tunability for visible light-emitting sources.

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Treatment Patterns, Costs, and Survival among Medicare-Enrolled Elderly Patients Diagnosed with Advanced Stage Gastric Cancer: Analysis of a Linked Population-Based Cancer Registry and Administrative Claims Database

  • Karve, Sudeep;Lorenzo, Maria;Liepa, Astra M;Hess, Lisa M;Kaye, James A;Calingaert, Brian
    • Journal of Gastric Cancer
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    • v.15 no.2
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    • pp.87-104
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    • 2015
  • Purpose: To assess real-world treatment patterns, health care utilization, costs, and survival among Medicare enrollees with locally advanced/unresectable or metastatic gastric cancer receiving standard first-line chemotherapy. Materials and Methods: This was a retrospective analysis of the Surveillance, Epidemiology, and End Results-Medicare linked database (2000~2009). The inclusion criteria were as follows: (1) first diagnosed with locally advanced/unresectable or metastatic gastric cancer between July 1, 2000 and December 31, 2007 (first diagnosis defined the index date); (2) ${\geq}65$ years of age at index; (3) continuously enrolled in Medicare Part A and B from 6 months before index through the end of follow-up, defined by death or the database end date (December 31, 2009), whichever occurred first; and (4) received first-line treatment with fluoropyrimidine and/or a platinum chemotherapy agent. Results: In total, 2,583 patients met the inclusion criteria. The mean age at index was $74.8{\pm}6.0years$. Over 90% of patients died during follow-up, with a median survival of 361 days for the overall post-index period and 167 days for the period after the completion of first-line chemotherapy. The mean total gastric cancer-related cost per patient over the entire post-index follow-up period was United States dollar (USD) $70,808{\pm}56,620$. Following the completion of first-line chemotherapy, patients receiving further cancer-directed treatment had USD 25,216 additional disease-related costs versus patients receiving supportive care only (P<0.001). Conclusions: The economic burden of advanced gastric cancer is substantial. Extrapolating based on published incidence estimates and staging distributions, the estimated total disease-related lifetime cost to Medicare for the roughly 22,200 patients expected to be diagnosed with this disease in 2014 approaches USD 300 millions.

Analysis of the load distribution and contact safety factor of PTO gears of a 71 kW class agricultural tractor

  • Baek, Seung-Min;Kim, Wan-Soo;Kim, Yeon-Soo;Lee, Nam-Gyu;Kim, Nam-Hyeok;Kim, Yong-Joo
    • Korean Journal of Agricultural Science
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    • v.47 no.2
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    • pp.327-335
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    • 2020
  • The purpose of this study was to analyze the load distribution and contact safety factor for the power take off (PTO) gear of a 71 kW class agricultural tractor. In this study, a simulation model of the PTO gear-train was developed using Romax DESGINER. The face load factor and contact safety factor were calculated using ISO 6336:2006. The simulation time was set at 2,736 hours considering the lifetime of the tractor, and the simulation was performed for each PTO gear stage at the engine rated power conditions. As a result of the simulation, the face load factors for the driving gear at the PTO 1st, 2nd and 3rd stages were 1.644, 1.632, and 1.341, respectively. The contact safety factors for the driving gear at the PTO 1st, 2nd and 3rd stages were 1.185, 1.216, and 1.458, respectively. As the PTO gear stage was increased, the face load factor decreased, and the contact safety factor increased. The load distributions for all the PTO gears were concentrated to the right of the tooth width. This causes stress concentrations and shortens the lifespan of the gears. Therefore, it is necessary to improve the face load factor and the contact safety factor with macro-geometry and micro-geometry.

Temperature distribution of ceramic panels of a V94.2 gas turbine combustor under realistic operation conditions

  • Namayandeh, Mohammad Javad;Mohammadimehr, Mehdi;Mehrabi, Mojtaba
    • Advances in materials Research
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    • v.8 no.2
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    • pp.117-135
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    • 2019
  • The lifetime of a gas turbine combustor is typically limited by the durability of its liner, the structure that encloses the high-temperature combustion products. The primary objective of the combustor thermal design process is to ensure that the liner temperatures do not exceed a maximum value set by material limits. Liner temperatures exceeding these limits hasten the onset of cracking which increase the frequency of unscheduled engine removals and cause the maintenance and repair costs of the engine to increase. Hot gas temperature prediction can be considered a preliminary step for combustor liner temperature prediction which can make a suitable view of combustion chamber conditions. In this study, the temperature distribution of ceramic panels for a V94.2 gas turbine combustor subjected to realistic operation conditions is presented using three-dimensional finite difference method. A simplified model of alumina ceramic is used to obtain the temperature distribution. The external thermal loads consist of convection and radiation heat transfers are considered that these loads are applied to flat segmented panel on hot side and forced convection cooling on the other side. First the temperatures of hot and cold sides of ceramic are calculated. Then, the thermal boundary conditions of all other ceramic sides are estimated by the field observations. Finally, the temperature distributions of ceramic panels for a V94.2 gas turbine combustor are computed by MATLAB software. The results show that the gas emissivity for diffusion mode is more than premix therefore the radiation heat flux and temperature will be more. The results of this work are validated by ANSYS and ABAQUS softwares. It is showed that there is a good agreement between all results.

Development of Vehicular Load Model using Heavy Truck Weight Distribution (II) - Multiple Truck Effects and Model Development (중차량중량분포를 이용한 차량하중모형 개발(II) - 연행차량 효과 분석 및 모형 개발)

  • Hwang, Eui-Seung
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.3A
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    • pp.199-207
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    • 2009
  • In this paper, new vehicular load model is developed for reliability-based bridge design code. Rational load model and statistical properties of loads are important for developing reliability-based design code. In the previous paper, truck weight data collected at eight locations using WIM or BWIM system are analyzed to calculate the maximum truck weights for specified bridge lifetime. Probability distributions of upper 20% total truck weight are assumed as Extreme Type I (Gumbel Distribution) and 100 years maximum weights are estimated by linear regression. In this study, effects of multiple presence of trucks are analyzed. Probability of multiple presence of trucks are estimated and corresponding multiple truck weights are calculated using the same probability distribution function as in the previous paper. New vehicular live load model are proposed for span length from 10 m to 200 m. New model is compared with current Korean model and various load models of other countries.

Comparative Study of AI Models for Reliability Function Estimation in NPP Digital I&C System Failure Prediction (원전 디지털 I&C 계통 고장예측을 위한 신뢰도 함수 추정 인공지능 모델 비교연구)

  • DaeYoung Lee;JeongHun Lee;SeungHyeok Yang
    • Journal of Korea Society of Industrial Information Systems
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    • v.28 no.6
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    • pp.1-10
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    • 2023
  • The nuclear power plant(NPP)'s Instrumentation and Control(I&C) system periodically conducts integrity checks for the maintenance of self-diagnostic function during normal operation. Additionally, it performs functionality and performance checks during planned preventive maintenance periods. However, there is a need for technological development to diagnose failures and prevent accidents in advance. In this paper, we studied methods for estimating the reliability function by utilizing environmental data and self-diagnostic data of the I&C equipment. To obtain failure data, we assumed probability distributions for component features of the I&C equipment and generated virtual failure data. Using this failure data, we estimated the reliability function using representative artificial intelligence(AI) models used in survival analysis(DeepSurve, DeepHit). And we also estimated the reliability function through the Cox regression model of the traditional semi-parametric method. We confirmed the feasibility through the residual lifetime calculations based on environmental and diagnostic data.

Evaluation of Allowable Criteria in First-Passage Probability Method for Caisson Sliding of Vertical Breakwater (직립방파제의 케이슨 활동에 대한 최초통과확률법의 허용기준 산정)

  • Kim, Seung-Woo;Suh, Kyung-Duck
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.25 no.5
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    • pp.317-326
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    • 2013
  • Probabilistic design methods can consider uncertainties of design variables and are widely used in the design of vertical breakwaters. The probabilistic design methods include a partial safety factor method, reliabilitybased design method, and performance-based design method. Especially the performance-based design method calculates the accumulated sliding distance during the lifetime of the breakwater or during a design storm. Recently a time-dependent performance-based design method has been developed based on the first-passage probability of individual sliding distance during a design storm. However, because the allowable criteria in the first-passage probability method are not established, the stability of structures cannot be quantitatively evaluated. In this study, the allowable first-passage probabilities for two limit states are proposed by calculating the first-passage probabilities for the cross-sections designed with various water depths and characteristics of extreme wave height distributions. The allowable first-passage probabilities are proposed as 5% and 1%, respectively, for the repairable limit state (allowable individual sliding distance of 0.03 m) and ultimate limit state (allowable individual sliding distance of 0.1 m). The proposed criteria are applied to the evaluation of the effect of wave-height increase due to climate change on the stability of the breakwater.

Black Hispanic and Black Non-Hispanic Breast Cancer Survival Data Analysis with Half-normal Model Application

  • Khan, Hafiz Mohammad Rafiqullah;Saxena, Anshul;Vera, Veronica;Abdool-Ghany, Faheema;Gabbidon, Kemesha;Perea, Nancy;Stewart, Tiffanie Shauna-Jeanne;Ramamoorthy, Venkataraghavan
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.21
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    • pp.9453-9458
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    • 2014
  • Background: Breast cancer is the second leading cause of cancer death for women in the United States. Differences in survival of breast cancer have been noted among racial and ethnic groups, but the reasons for these disparities remain unclear. This study presents the characteristics and the survival curve of two racial and ethnic groups and evaluates the effects of race on survival times by measuring the lifetime data-based half-normal model. Materials and Methods: The distributions among racial and ethnic groups are compared using female breast cancer patients from nine states in the country all taken from the National Cancer Institute's Surveillance, Epidemiology, and End Results cancer registry. The main end points observed are: age at diagnosis, survival time in months, and marital status. The right skewed half-normal statistical probability model is used to show the differences in the survival times between black Hispanic (BH) and black non-Hispanic (BNH) female breast cancer patients. The Kaplan-Meier and Cox proportional hazard ratio are used to estimate and compare the relative risk of death in two minority groups, BH and BNH. Results: A probability random sample method was used to select representative samples from BNH and BH female breast cancer patients, who were diagnosed during the years of 1973-2009 in the United States. The sample contained 1,000 BNH and 298 BH female breast cancer patients. The median age at diagnosis was 57.75 years among BNH and 54.11 years among BH. The results of the half-normal model showed that the survival times formed positive skewed models with higher variability in BNH compared with BH. The Kaplan-Meir estimate was used to plot the survival curves for cancer patients; this test was positively skewed. The Kaplan-Meier and Cox proportional hazard ratio for survival analysis showed that BNH had a significantly longer survival time as compared to BH which is consistent with the results of the half-normal model. Conclusions: The findings with the proposed model strategy will assist in the healthcare field to measure future outcomes for BH and BNH, given their past history and conditions. These findings may provide an enhanced and improved outlook for the diagnosis and treatment of breast cancer patients in the United States.

Distribution and Human Risk Assessment of Polycyclic Aromatic Hydrocarbons and Polychlorinated Biphenyls in Sediments and Fish from Suyoung Estuary of Busan, Korea (부산 수영강 하구역의 퇴적물과 어류에서 다환방향족탄화수소 및 폴리염화비페닐의 농도분포와 인체 위해도 평가)

  • Lee, Bongmin;Yoon, Sera;Bak, Sihyeon;Lee, In-Seok;Choi, Minkyu
    • Journal of Environmental Analysis, Health and Toxicology
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    • v.21 no.4
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    • pp.252-263
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    • 2018
  • Distributions of 15 PAHs and 82 PCBs were investigated in sediment and fish samples collected from the Suyoung Estuary of Busan, one of the most urbanized and newly contaminated areas in Busan. The concentrations of $S_{15}PAH$ in sediments ranged from 17.9 to 777 ng/g-dry and were mainly originated from combustion processes. The concentrations of $S_{82}PCB$ in sediments ranged from 0.55 to 12.5 ng/g-dry and were significantly correlated with those of 12 dioxin-like PCBs and 6 non-dioxin like PCBs. Higher concentrations of PAHs and PCBs were found in the upper river and the inner Suyoung Bay than in marina and the outer Suyoung Bay. No sites exceeded the ecotoxicological values of PAHs and PCBs in marine sediments. Benzo[a]-pyrene was not detected in fish samples and the concentrations of $S_4PAH$ (0.15~0.45 ng/g-wet) were lower than the maximum level set by EU. The levels of PCBs in fish samples were at less than 1% of the Korean maximum level and 2% of the EU maximum level. The concentrations of dioxin-like PCBs were $0.01{\sim}0.32pg-TEQ_{WHO-2005}/g-wet$, and the highest concentration was found in eels, which were at less than 5% of the EU maximum level. Dietary intakes of PAHs and PCBs through fish consumption were estimated, and their lifetime cancer risk and non-cancer risk were much lower.