• Title/Summary/Keyword: life-stress model

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Evaluation of Senescence Induced Prematurely by Stress. Application for cosmetic active ingredients

  • Morvan, Pierre-Yves;Romuald Vallee
    • Proceedings of the SCSK Conference
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    • 2003.09a
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    • pp.285-290
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    • 2003
  • Living cells are continuously subject to all sorts of stress such as ultraviolet rays on skin cells. Tests made in various laboratories show that when young fibroblasts (Le. at the beginning of their proliferate life) were repeatedly put under stress at subletal doses, they acquired a phenotype similar to Senescence Induced Prematurely by Stress (SIPS). The work presented hereafter was made on a new model of senescence induced prematurely by stress from ultraviolet Brays (UVB). The human fibroblast model was put under repeated UVB stress, causing SIPS. Several ageing biomarkers were used in order to characterise the cells that underwent stress:. an increase in the proportion of positive cells with senescence associated $\beta$-galactosidase activity (SA $\beta$-gal) measured by a specific coloration,. the proportion in the different morphological stages that fibroblasts undergo during culture visualised by microscopic observation,. the expression of genes known for overexpressing during senescence, particularly fibronectin and apolipoprotein J, measured by Real Time-PCR,. the common deletion of 4,977 bp in mitochondrial DNA, evaluated by nested PCR. Studying the variation of these 4 biomarkers, we have evaluated the protective effect of a Laminaria digitata extract (LDE) that can be used as a natural active ingredient for anti-ageing cosmetics.

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Analysis on the Fatigue Crack Propagation of Weld Toe Crack through Residual Stress Field (잔류응력장을 전파하는 용접 토우부 균열의 전파해석)

  • 김유일;전유철;강중규;한종만;한민구
    • Journal of Welding and Joining
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    • v.18 no.5
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    • pp.33-40
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    • 2000
  • Fatigue crack propagation life of weld toe crack through residual stress field was estimated with Elber's crack concept. Propagation of weld toe crack is heavily influenced by residual stress caused by welding process, so it is essential to take into account the effect of residual stress on the propagation life of weld toe crack. Fatigue crack at transverse and longitudinal weld toe was studied respectively, which represent typical weld joint in ship structure. Numerical and experimental studies are performed for both cases. Residual stress near weldment was estimated through nonlinear thermo-elasto-plastic finite element method, and residual stress intensity factor with Glinka's weight function method. Effective stress intensity factor was calculated with Newman-Forman-de Koning-Henriksen equation which is based on Dugdale strip yield model in estimating crack closure level U at different stress ratio. Calculated crack propagation life coincided well with experimental results.

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Factors Affecting of life stress in Middle-aged on Depression: -Mediating effect of Self-esteem and Social support- (중년 남성의 생활스트레스가 우울에 미치는 영향 -자아존중감, 사회적 지지의 매개효과-)

  • Song, Ji Hyeun;Seong, Mi Hyeon
    • Journal of Digital Convergence
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    • v.19 no.3
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    • pp.235-244
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    • 2021
  • This study was conducted to confirm the mediating effect of self-esteem and social support in the relationship between life stress and depression in middle-aged men. Data analysis was performed using the SPSS/WIN 25.0 program, t-test, ANOVA, pearson's correlation coefficient, SPSS Process Macro (Model 4), and bootstrapping approach. As a result of this study, when considering the effect of self-esteem, a parameter in the relationship between life stress and depression, the direct effect of life stress on depression was .49. Considering the effect of social support as a parameter, the direct effect of life stress on depression was .50. That is, when the parameters were not considered, life stress decreased compared to the overall effect of .62 on depression. Through this, it was confirmed that self-esteem and social support had a mediating effect in the relationship between life stress and depression.

Influence of Perceived Mother-Grandmother Conflicts on Subjective Well-being among Multicultural Children: Focused on Mediating Effect of Acculturative Stress and Satisfaction of School Life (다문화가정 자녀의 지각된 어머니 고부갈등이 주관적 웰빙에 미치는 영향: 문화적응 스트레스와 학교생활적응의 매개효과를 중심으로)

  • Kim, Bok-Hee;Suh, Kyung-Hyun
    • The Journal of the Korea Contents Association
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    • v.21 no.8
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    • pp.498-506
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    • 2021
  • This study identified the relationship between perceived mother-grandmother conflicts and subjective well-being among multicultural children, and examined the double mediating model of acculturative stress and adjustment to school life on that relationship. Participants were 205 male and female adolescents living at J county in Gangwon-do. PROCESS Macro 3.5 Model 6 was used for analysis of a double mediating effect. Results revealed that perceived mother-grandmother conflicts was positively correlated with acculturative stress of multicultural children, and negatively correlated with adjustment to school life and subjective well-being. And, acculturative stress of multicultural children was negatively correlated with adjustment to school life and subjective well-being, whereas adjustment to school life was positively correlated with subjective well-being. This study found that acculturative stress and adjustment to school life were sequentially mediating perceived mother-grandmother conflicts and subjective well-being of multicultural children. These findings suggest that the perceived mother-grandmother conflicts might cause multicultural children to experience acculturative stress, and as a result, their subjective well-being level might be reduced due to their low adjustment to school life.

Family Surrogates' Decision Regret and Psychological Stress about End-of-Life Cancer Treatments: Path Analysis (말기 암환자 가족의 대리적 연명의료 결정에 대한 치료결정 후회 및 심리적 스트레스: 경로모형 분석)

  • Kim, Su Hyun
    • Journal of Korean Academy of Nursing
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    • v.48 no.5
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    • pp.578-587
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    • 2018
  • Purpose: This study aimed to understand the mechanisms of decision regret and stress of family surrogates' end-of-life decision making using an exploratory path model. In particular, the research identified the direct effects of perceptions of uncertainty and effective decisions on decision regret and stress, and examined the indirect effects of being informed, having clear values, and being supported for decision regret and the stress of end-of-life decision making through the mediating variables of perceptions of uncertainty and effective decisions. Methods: Data were collected from 102 family surrogates who had participated in end-of-life decision making for patients with terminal cancer in a tertiary hospital. Results: Perception of effective decisions was a significant direct predictor of decision regret, and uncertainty was a significant predictor of stress among the participants. Being informed, having clear values, and being supported had a significant indirect influence on decision regret through the perception of effective decisions among family surrogates. However, only having clear values had a significant indirect influence on stress through the perception of uncertainty. The model explained 63.0% of decision regret and 20.0% of stress among the participants and showed a good fit with the data, ${\chi}^2=12.40$ (df=8, p=.134), TLI=.97, and RMSEA=.07. Conclusion: Nurses can support family surrogates in end-of-life decision-making processes to decrease their decision regret by providing information about end-of-life care choices, clarifying personal values, and supporting the decision-making process, and to relieve their stress by facilitating the clarification of personal values.

Fatigue Durability Analysis due to the Classes of Automotive Wheels (자동차 휠의 종류별 피로 내구성 해석)

  • Han, Moonsik;Cho, Jaeung
    • Transactions of the Korean Society of Automotive Engineers
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    • v.22 no.6
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    • pp.68-74
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    • 2014
  • This study analyzes structural stress and fatigue about three types of automotive wheels. As maximum equivalent stresses at 1, 2 and 3 types become lower than the yield stress of material and deformations become minute, theses types are thought be safe on durability. Type 2 model has the most fatigue life among three kinds of types and the rest of models with fatigue lives are shown in the order of type 1 and 3. As the most fatigue frequency of type 2 model happens at the state of average stress and amplitude stress on the stress range narrower than type 1 or 3, type 2 model becomes most stable. In case of type 2 with the state near the average stress of 0 MPa and the amplitude stress of 300MPa, the possibility of maximum damage becomes 30%. This stress state can be shown as the most damage possibility. These study results can be effectively utilized with the design on automotive wheel by anticipating and investigating prevention and durability against its damage.

Structural Analysis of the Health Related Quality of Life in Working Women with Preschool Children (미취학 자녀를 둔 취업여성의 건강관련 삶의 질 구조분석)

  • Lee, Hye Gyeong;Kim, Sun-Hee
    • Research in Community and Public Health Nursing
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    • v.31 no.3
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    • pp.223-233
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    • 2020
  • Purpose: The purpose of this study was to construct a model that describes the health related quality of life in working women with preschool children and to verify the goodness of fitness of the model. Methods: The data were collected with a structured self-report questionnaire from 483 working women with preschool children. Results: The modified model showed a reasonable fitness to the data. Social support, job satisfaction, parenting stress, sense of coherence and depression accounted for 78% of the health related quality of life in working women with preschool children. Conclusion: This study suggests that the health related quality of life in working women with preschool children can be improved by reducing parenting stress and depression level, and by increasing social support, job satisfaction, and sense of coherence. Depression can also be managed by reducing parenting stress and by increasing job satisfaction and sense of coherence. Based on the results of this study, it is necessary to develop intervention programs to increase the health related quality of life or to decrease depression in working women.

Fatigue Life Prediction of FRP Composites under Uniaxial Tension and Pure Torsion Loadings (인장-비틀림 하중에 의한 섬유강화 복합재료의 피로수명 예측)

  • 박성완;이장규
    • Proceedings of the Korean Society of Machine Tool Engineers Conference
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    • 2003.04a
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    • pp.352-361
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    • 2003
  • A fatigue damage accumulation model based on the continuum damage mechanics theory was develope(1 where modules decay ratios in tension and shear on used as indicators for damage variables D . In the model, the damage variables are considered to be second-order tensors. Then the maximum principal damage variable, $D^*$ is introduced According to the similarity to the Principal stress, $D^*$ is obtained as the maximum eigen value of damage tensor [D']. Under proportional tension and torsion loadings, fatigue lives were satisfactorily predicted at any combined stress ratios using the present model in which the fatigue characteristics only under uniaxial tension and pure torsion loadings on needed. Fatigue life prediction under uniaxial tension and pure torsion loadings, was performed based on the damage mechanics using boundary element method.

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Fatigue Life Prediction of FRP Composites under Uniaxial Tension and Pure Torsion Loadings (인장-비틀림 하중에 의한 섬유강화 복합재료의 피로수명 예측)

  • Park Sung-Oan
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.13 no.6
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    • pp.64-73
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    • 2004
  • A fatigue damage accumulation model based on the continuum damage mechanics theory was developed where modulus decay ratios in tension and shear were used as indicators for damage variables D. In the model, the damage variables are considered to be second-order tensors. Then, the maximum principal damage variable, $D^*$ is introduced. According to the similarity to the principal stress, $D^*$ is obtained as the maximum eigen value of damage tensor [D]. Under proportional tension and torsion loadings, fatigue lives were satisfactorily predicted at any combined stress ratios using the present model in which the Fatigue characteristics only under uniaxial tension and pure torsion loadings were needed. Fatigue life prediction under uniaxial tension and pure torsion loadings, was performed based on the damage mechanics using boundary element method.

Stress based Fatigue Life Prediction for Ball Bearing (응력 기반 볼 베어링의 접촉피로수명 예측)

  • Kim Tae-Wan;Lee Sang-Don;Cho Yong-Joo
    • Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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    • 2004.11a
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    • pp.339-349
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    • 2004
  • The method for fatigue life prediction of ball bearing is proposed applying the algorithm of contact fatigue prediction based on stress analysis. In order to do this, a series of simulation such as initial surface stress analysis, EHL analysis, subsurface stress analysis and fatigue analysis are conducted from the loading at each ball location calculated for a bearing subjected to external bearing load and contact shape function. And uniaxial fatigue tests are performed to obtain fatigue parameter of AISI 52100 steel. It was found that since stress is usually higher at the inner raceway contact than at the outer raceway contact, fatigue failure occurs on the inner raceway first. When the fatigue life calculated in the stress-based method are compared with $L_{50}$ life of L-P model, Crossland criterion for the radial load increment is similar to $L_{50}$ life and Dang Van criterion for the axial load increment is similar. In the case of EHL contact. there is no difference of fatigue life between dry contact and EHL contact, when maximum Hertz pressure exceeds 2.5GPa.

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