• The Korean Journal of Physiology and Pharmacology
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• v.18 no.4
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• pp.313-320
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• 2014

The study was conducted to investigate the role of vitamin E in the high altitude hypoxia-induced damage to the intestinal barrier in rats. Sprague-Dawley rats were divided into control (Control), high altitude hypoxia (HH), and high altitude hypoxia + vitamin E (250 mg/kg $BW^*d$) (HV) groups. After the third day, the HH and HV groups were placed in a hypobaric chamber at a stimulated elevation of 7000 m for 5 days. The rats in the HV group were given vitamin E by gavage daily for 8 days. The other rats were given equal volume saline. The results showed that high altitude hypoxia caused the enlargement of heart, liver, lung and kidney, and intestinal villi damage. Supplementation with vitamin E significantly alleviated hypoxia-caused damage to the main organs including intestine, increased the serum superoxide dismutase (SOD) (p< 0.05), diamino oxidase (DAO) (p< 0.01) levels, and decreased the serum levels of interleukin-2 (IL-2) (p< 0.01), interleukin-4 (IL-4) (p<0.001), interferon-gamma ($IFN-{\gamma}$) (p<0.01) and malondialdehyde (MDA) (p<0.001), and decreased the serum erythropoietin (EPO) activity (p<0.05). Administration of vitamin E significantly increased the S-IgA (p<0.001) in ileum and significantly improved the expression levels of occludin and $I{\kappa}B{\alpha}$, and decreased the expression levels of hypoxia-inducible factor 1 alpha and 2 alpha ($HIF-1{\alpha}$ and $HIF-2{\alpha}$), Toll-like receptors (TLR4), P-$I{\kappa}B{\alpha}$ and nuclear factor-${\kappa}B$ p65(NF-${\kappa}B$ P65) in ileum compared to the HH group. This study suggested that vitamin E protectis from intestinal injury caused by high altitude hypoxia environment. These effects may be related to the HIF and TLR4/NF-${\kappa}B$ signaling pathway.

• The Journal of Korean society of community based occupational therapy
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• v.8 no.1
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• pp.1-10
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• 2018

Objective : The purpose of study is to validate the clinical utility and usability of the Korean version of the Life Space Assessment(K-LSA) which is an assessment tool of community mobility of older adults. Methods : Surveys on the clinical utility and usability of the K-LSA are carried out with a total of aoaa60 occupational and physical therapists. The surveys included the multiple choice questions on the clinical utility and open questions on the usability. Responses to multiple questions are post processed by frequency analysis and technical statistics, and responses to the open questions are categorized by common factors in each questions. Results : Average value of clinical utility ranges from 3.6 to 4.0 with positive responses of 'fair (3 point)', 'agree (4 point)' and 'strongly agree (5 point)' being 95~100%. Average value for clinical usability ranges from 3.6 to 4 with positive answers of 'fair (3 point)', 'easy (4 point)' and 'very easy (5 point)' being 88.3~100%. Additionally out of open-type questions of clinical usability, it was pointed out that the concept of 'neighborhood' for the life space level 3 and 4 is unclear. Conclusion : The current study and research outcomes showed that the K-LSA is a validated tool in Korean health care system for the clinical utility and usability in measuring community mobility, and that it is straightforward in practical use. It will help clinicians and therapists promote the social participation of older adults, and set an intervention goal for enhancing community mobility. It will further help clinicians and researchers in education and research for medical intervention and goal-setting.

• Korean Institute of Interior Design Journal
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• no.15
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• pp.86-93
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• 1998

An Apartment Veranda is a transitive space which is being used for many different purpose. A Rear Veranda which is connected to the kitchen is an important space for the housekeeping work and it should be planned carefully to reflect the rational and functional designs. Therefore the objective of this research is to suggest a systematic basis for the practical space planning of the Rear veranda that meets the varied needs of consumers by examining its usage pattern through the analysis of the apartment occupant's behavior pattern stored item the degree of satisfaction and consumer requirements. The research was conducted mainly on apartments built after 1990. The following are the conclusions from the research : 1. Most of the research respondents were aware of the absolute need for the Rear veranda. But they expressed dissatisfaction with the space usage. This indicates that the Rear Veranda planning does not reflect the functionality of the space and concentrates on the idea of providing consumers a service space based on the size of the apartment instead. 2. Although the Rear veranda is used as the multipurpose housework space it is mainly used as the laundry and storage space. This shows a big deviation from the concept of the utility space. Because the behavior pattern associated with the Rear Veranda is largely influenced by the traditional life pattern the development of the Rear Veranda as an exclusive space for the housekeeping work. 3. According to a high frequency of the storage of the laundry related item in the Rear Veranda indicated by the research the Rear veranda is used as the laundry room as well as a auxiliary storage space by most people. The installation of gas range is expected to increase due to the expansion of the usage function of the Rear Veranda space. The installation of a specialized refrigerator to store the traditional food is demanded. 4. Consumers need more efficient and functional storage device because the temporary shelves are often being used as the storage device. The perception of the storage device is assumed to have been influence by the traditional life style.

• Journal of the Korean housing association
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• v.13 no.5
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• pp.51-58
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• 2002

The purpose of this study is to examine residents' perception and needs for storage according to the family life cycle. In order to achieve our goal, the questionnaire survey is used. We sample the questionnaire surveys of 250 apartment households in Seoul. The data collect by the questionnaire survey was analyzed by examining the frequency, percentage on the SPSS/PC+ Statistics package. The results of the study are obtained as follows: 1) In research on the actual storage condition, residents tend to feel constraint on storage of the season goods and the storage satisfaction on the service area is founded lowest. Therefore, it is needed more efficient space plan on the balcony storage and the interior storage for the season goods. 2) In research on the storage consciousness and attitude, residents tend to keep the goods of no use and prefer to arrange neatly rather than use conveniently. Therefore, it is needed more efficient space in the balcony for the storage of the goods of no use and the colsed furniture rather than the open furniture is suited for arrangement. 3) In research on the storage needs, needs for the built-in furniture in all family life cycle show highly and residents want to a space for the exclusive use of the storage. In a solution, we propose to equip with the interior storage and the exterior cooperative storage

• Journal of the Korean Institute of Rural Architecture
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• v.12 no.1
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• pp.41-48
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• 2010

A house is basic unit of human being living space and it reflects an occupation, family relation, a life style and sense of value of resident. The purpose of this study was to research the continuity of traditional elements and contemporary change of Japanese houses by field study and literature research. The subject of this study was sixteen houses of Miyashiro, Saitama pref. in Japan. The results of this study are as follow as. First, the traditional elements of contemporary Japanese houses are tatami floor room, tsuzukima, zashiki, dokonoma, butsudan, amado. Second, the tatami is symbol of Japanese living space. Wasizus maintains a traditional characteristic, but it is developed and fixed properly change in contemporary life. Third, the traditional elements of Japanese houses are continuing in the modern houses, and they are continuously changed the feature from recreate. It can be a connection of a hereditary factor of residential culture. Four, the continuity of modern change and traditional element of the Japanese houses can be understood the change of the structural and spatial responding method to accommodates a life.

• Korean Institute of Interior Design Journal
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• v.13 no.2
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• pp.91-99
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• 2004

This study aims to embody material and non-material factors forming space and to explain our experience in space. Space is formed by material factors and their disposition. One space becomes a new space by such factors 'arrangement. Nevertheless, one space is never swayed by material factors and their disposition. Space is a reflection of social relations and historical process, and is also affected by its users. Space can not neutrally exist, for it compels its users to keep a specific life style. Space users have experience in space by practice. Practice enables its users to experience various relationships space makes, and as well it allows them to have creative experience in space by twisting them and inducing a new relationship.

• Journal of the Korean Geographical Society
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• v.39 no.6 s.105
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• pp.922-932
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• 2004

This paper uses the diary entitled Kieo, which was kept by Ryu Hyeong-eop for 38 years, to analyze the active space of small-scale Yangban landlords. Ryu lived during the period spanning from the end of the Taehan Empire through the colonial era. The researcher classified the contents of Kieo into different sections which were divided according to different stages of the writer's life, his objectives, destinations, and periods, and based on the writer's life-cycle, strived to recreate his spatial activities. As a result, researcher was able to ascertain that Ryu's spatial activities gradually increased, and that his active space also continuously expanded. Ryu's active space during his youth was narrow and centered around certain specific places. However, this active space gradually increased as time went by. It was during the middle stages of his life that the volume of his spatial activities was the heaviest. In addition, the objectives of his outings also became more diversified over time. This change was originated in the larger changes in his roles within the family and community, as well as by the changes in the periodic situation. Moreover, the regional sphere of Ryu's outings, including his day and over nights trips, allowed the researcher to form a better understanding of the daily living area of the Yangban.

• Journal of the Korean housing association
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• v.27 no.5
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• pp.73-81
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• 2016

Focused on developing form of Western architecture, invisible elements covering actual human life has been dealt with separately and the time was turned away and disparaged. But now the phenomenology, arranging such a meeting of space and time, gives opportunity to look at the actual life in architecture. Recently, Guille Deleuze and Merleau-Ponty tried to recover the sense of touch segregated in skin from body keeping eyes for distance. And the activity can be happened by being connected to the body rather than to eye in the space. From the phase of recognition where the human body tries to identify the object in the space considering a time, it will be changed for the subject to the phase of space-time structure. If the tactility is to erase the distance different from the visuality in dichotomy, it will be occurred to having a tension and makes new relationship to work trying to move the subjective point of view in object. Like this evidence in analysis of architecture, it can be found these in the Korean traditional architecture rather than Western architecture in terms of emphasizing the time and space. And this study will be intensive to the side of the Phenomenology how it is being connected to the movement in the space and time for the subject and object.

• Korea Science and Art Forum
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• v.19
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• pp.515-525
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• 2015

Along with a rapid increase in the number of 1-person households where the concept of 1-person consumption and 1-person economy is emphasized, the proportion of 1-person household in Korea occupies a 25.3% at present, and the number is expected to grow continuously. And this rapid increase will bring about a host of problems such as housing shortage in the metropolitan area, egoism, loneliness felt by individuals, and other social problems such as crime. As an alternate movement to this phenomenon, concern on and interest in community, community culture, and sharing of space are on the rise, together with concern on and preference for sharehouse culture. In news media as well, articles on life shared with members of a sharehouse often appear. This sharehouse, which is widely spread and well received in Japan, not only reduces economic burden but also creates their own community and promotes their own culture. In this sense, it is a new way of life that represents benefits of sharing, well beyond just economic interests. Accordingly, In this research, an attempt was made tp examine the circumstances in the use of space based on existing studies on sharehouse characteristics in order to shed new lights on the meaning that non-characteristic space concept of the traditional residential space has as the concept of sharehouse space by considering it in connection with the non-characteristic space concept of the Korean traditional residential space where diverse circumstances occur centered on communal life and which were accepted by all naturally.

• Korean Institute of Interior Design Journal
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• v.21 no.4
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• pp.31-39
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• 2012

Ecosystem and environment have been a serious challenge facing the modern society. It's been the new paradigm from ecological view of the world and the alternative based on Orientalism. From the Oriental standpoint, ecological aesthetics and sustainable architecture are no longer new, which then servers the background of this study. The nature and the space, the life where the human is harmonized and integrated and the wish to make the balance through that life are the basic philosophy which the Orientalism has pursued. Based on such a basic concept, the study is intended to review the connectivity, expression approach and the features in Korean traditional residential space based on previous studies on ecological aesthetics and sustainable architecture. Such attempt is meaningful in seeking the possibility of presenting the new frame as well as forming the various views to the traditional space and spatial recognition. The nature was categorized into tangible element and intangible element and also direct approach and indirect approach before evaluating the characteristics. Sustainable architecture is not the concept to simply maintain or sustain the environment, but plays more important role in economical aspect. Traditional space accommodates the nature and circulation principle and the circulation in the nature controls the energy and enhances the efficiency, playing significant role. The nature itself serves the alternative energy and has the aesthetic element in such a way of concealing itself. This study is intended to analyze the Byulseo Jeongwon which formed many relations with the nature and the residential space, thereby identifying the expression characteristics of eco-aesthetic sustainable architect. This study offers the answers with regard to the coexistence of the expression characteristics of sustainable architecture with the nature, space and the human from eco aesthetic viewpoint as well as the solution in dealing with the ecological and environmental challenges. Furthermore, it suggested the possibility that the traditional space would possibly be succeedable in new and creative way and sought the way for coexistence among the nature, space and human and eco aesthetics, and finally paved the pivotal foundation as the sustainable design alternative in future.