• 한국컴퓨터정보학회논문지
• /
• 제19권9호
• /
• pp.65-73
• /
• 2014

무선 센서 네트워크에서도 다른 네트워크와 마찬가지로 시간 관계를 유지하는 것이 중요하므로, 무선 센서 네트워크의 특성을 고려한 시각 동기화 프로토콜인 IBS(Indirect-Broadcast Synchronization)가 2012년에 개발되었다. IBS는 클러스터 트리 형태에서 동작하므로 일반 노드보다 더 많은 에너지를 소모하는 클러스터 헤더에 의해서 주로 네트워크 전체 수명이 좌우될 수 있다. 이 논문에서는 클러스터 트리를 부분적으로 재구성함으로써 전체 에너지 소모를 줄이고 네트워크 수명을 연장시키는 향상된 IBS(EIBS)를 개발하고자 한다. 다른 트리 구성 접근 방식과 비교할 때, 이 논문에서 사용된 방법은 알고리즘이 간단할 뿐만 아니라 전력 소모나 네트워크 수명 면에서 더 효율적이다.

• Journal of Chest Surgery
• /
• 제3권1호
• /
• pp.3-12
• /
• 1970

During the last 10 years of period, one hundred patients with various pulmonary diseases were pneumonectomized upon at the Department of Chest Surgery of Pusan University Hospital. This paper is concerned with the clnical results of these patients along with the serious postoperative complications such as postoperative intrapleural infection and hemorrhage. The results were obtained as follows. 1.Left pneumonectomy was done in sixty-six of 100 patients [66 %] and the right one was done in the rest thirty-four[34 %]. The ratio between left and right was nearly 2:1. 2.Of all oostoperative complications, the intrapleural infection was most common, and these were 53 % in empyema thoracis and 12.7 % in pulmonary tuberculosis respectively. 3.More postoperative complications could be seen after right pneumonectomy than the left one. 4.It was thought that the postoperative intrapleural infection was closely correlated with the methods of pleural dissection at pneumonectomy,postoperatlve tube drainage, time of operation, massive hemorrhage during operation, prolongation of bleeding time, and dysfunction of the liver. 5.The repeated thoracenteses with infusion of neomycin into the infected thoracic cavity and intravenous administrations of the high units of penicillin were effective in treatment of the postoperative intrapleural infection, however, the refractory cases have to be cured by thoracoplasty with open window. 6.Immediate secondary open thoracotomy appears to be the method of choice in life saving who developed massive intrathoracic hemorrhage after pneumonectomy. 7.The mortality rate was 10 % in our cases and the main causes of death were postoperative respiratory insufficiency, pulmonary edema, hemorrhage and sudden cardiac arrest.

• KSBB Journal
• /
• 제6권1호
• /
• pp.45-54
• /
• 1991

The aims of this study were investigated the antitumor effects and immunological activities of lipopolysaccharides (LPS) extracted from Proteus vulgaris RH-90 toward sarcoma-180 cells. LPS extracted from Proteus vulgris RH-90 was irradiated with gamma ray for detoxification. The tumor incidence of sarcoma-180 occurs all group which injected with gamma ray irradiated LPS and tumor of sarcoma-180 was necrotized with breeding in the injected group of l0$\mu\textrm{g}$ LPS. The inhibition ratio of tumor growth showed at the highest level of 60.88% when 5$\mu\textrm{g}$ gamma ray irradiated LPS was injected into mice. The prolongation ratio of life showed 20.72% when injected into mice with gamma ray irradiated LPS of 5$\mu\textrm{g}$. In the effect of immunological activity, the number of circurating leucocyte and peritoneal exudate cells were increased significantly in the treatment group than that control group, and dose-dependent response indicated by the increase of weights of immunorgans which revealed the improvement of immunity. The effect of macrophage on phagocytes, there were not found the differences between phagocytic and corrected phagocytic index.

• 한국식품영양과학회지
• /
• 제25권5호
• /
• pp.865-870
• /
• 1996

감잎의 시료 중 항돌연변이 효과와 암세포 증식 억제효과가 컸던 감잎의 헥산, 클로로포름 획분 및 감잎 탄닌의 항암효과를 Sarcoma-180 종양세포를 이용하여 살펴 보았다. Sarcoma-180 종양세포에 대한 시료의 세포 독성작용을 관찰한 후 세포에 큰 영향을 주지 않는 범위내에서 고형암 성장저지 효과 및 수명 연장 효과를 살펴 본 결과 감잎의 헥산 획분이 59.6%로 가장 높은 고형암 성장 저지율을 나타냈으며 수명 연장 효과도 대조군의 경우 17.4일인데 반해 헥산 획분을 투여한 경우 생존일수가 23.6일로 가장 큰 수명 연장 효과가 관찰되었다. 면역 관련 장기 중 하나인 비장의 체중에 대한 중량 변화는 대조군의 경우 0.6%인데 반해 감잎의 헥산 및 클로로포름 획분 그리고 감잎 탄닌의 경우 0.7%, 0.8%, 0.8%로 약간의 증가를 나타내었다.

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 2007년도 추계학술대회 논문집
• /
• pp.503-503
• /
• 2007

본 논문에서는 지중배전(22.9kV) 선로에 사용되는 지상변압기를 대상으로 수행한 방열해석 및 개선과 변압기수명연장에 관한 검토 결과를 수록하였다. 변압기의 열화메커니즘에 대한 문헌 조사를 통해 변압기 온도와 수명간의 관계를 작도하였는바, 수명 평가를 위한 핵심 인자로 열에 의한 절연지의 열화에 초점을 맞추었다. 기존 외함에 설치된 방열구중 상부 위치를 상부판에도 변경하는 경우 약25%의 통풍량 증가 효과를 기대할 수 있을 것으로 평가 되었으며 상부판과 내함 사이에 형성되던 고온 영역에서의 온도를 약$15^{\circ}C$정도 낮출 수 있는 것으로 나타났다. 절연지의 인장강도 변화로 평가한 수명예측 곡선에 따르면 약$10^{\circ}C$의 은도 저감은 약10배의 수명 연장 효과를 가져오는 것으로 나타난바, 본 연구에서 확인한 방열구의 위치 변경에 따른 지상기기 내부의 온도 저하는 변압기 수명을 연장하는데 일조할 것으로 기대된다. 기존 지상변압기에서의 방열구조를 통해 변압기 온도와 수명간의 관계를 작도하였는바, 수명 평가를 위한 핵심인자로 효과적으로 방열할 수 있는 새로운 외함의 구조 및 디자인을 제시하고 시뮬레이션을 통해 개선효과를 예측하였다. 또한, 개선된 모델을 가지고 실제 변압기를 제작한 후 부하를 인가하여 개선전과 후에 대한 방열효과를 실증시험을 통해 확인하였다.

• Journal of Preventive Medicine and Public Health
• /
• 제39권1호
• /
• pp.7-12
• /
• 2006

Throughout the century, based on the precedent set by Flexner in the United States, almost every subsequent report on the reform of medical education has pointed out the need for more prevention-oriented teaching in the curriculum. This has been particularly so in countries like Korea where the basic public health services have been so important for the improvement of health of the people. And, in fact, preventive medicine and public health have contributed a great deal to the prevention of communicable diseases and prolongation of life expectancy. Recently, however, along with the educational reform that emphasizing the interdisciplinary teaching, integration of basic science and clinical education, and centralization of responsibility for the medical education curriculum, concerns are being voiced by preventive medicine educators. These concerns are primarily centered around the fear that the implementation of interdisciplinary, centrally administered courses would result in a weakening of content and teaching expertise as well as a loss of departmental power and control. This paper foresees that preventive medicine and public health will be more important in Korea in the future and proposes that preventive medicine educators will have to step forward and turn the challenges of curricula restructuring into opportunities to expand the role of preventive medicine in the curricula of their institutions.

• Nuclear Engineering and Technology
• /
• 제40권4호
• /
• pp.269-276
• /
• 2008

Operational license of WWER-440/213 units at Paks NPP, Hungary is limited to the design lifetime of 30 years. Prolongation by additional 20 years of the operational lifetime is feasible. Moreover, enhancement of the reactor thermal power by 8% will increase both the net power output and the competitiveness of the plant. Paks NPP is a pioneer considering the power up-rate and preparation of long-term operation of WWER-440/213 design. Systematic preparatory work for long-term operation of Paks NPP has been started in 2000. A regulatory framework and a comprehensive engineering practice have been developed. According to the authors view, creation of a gapless engineering system via consequent application of best practices, and feed-back of experiences together with proper consideration of WWER-440/V213 features are the decisive elements of ensuring the safety of long-term operation. That systematic engineering approach is in the focus of recent paper. Key elements of justification and measures for ensuring the safety of long-term operation of Paks NPP WWER-440/213 units are identified and discussed. These are the assessment of plant condition and review of adequacy of ageing management programmes, also the review, validation and reconstitution of time limited ageing analyses as core tasks of licence renewal.

• Journal of Dental Anesthesia and Pain Medicine
• /
• 제23권1호
• /
• pp.45-51
• /
• 2023

Andersen-Tawil syndrome (ATS) is a rare genetic disease characterized by a triad of episodic flaccid muscle weakness, ventricular arrhythmias, and physical anomalies. ATS patients have various cardiac arrhythmias that can cause sudden death. Implantation of an implantable cardioverter-defibrillator (ICD) is required when life-threatening cardiac arrhythmias do not respond to medical treatment. An 11-year-old girl underwent surgery for an ICD implantation. For general anesthesia in ATS patients, anesthesiologists should focus on the potentially difficult airway, serious cardiac arrhythmias, such as ventricular tachycardia (VT), and delayed recovery from neuromuscular blockade. We followed the difficult airway algorithm, avoided drugs that can precipitate QT prolongation and fatal cardiac arrhythmias, and tried to maintain normoxia, normocarbia, normothermia, normoglycemia, and pain control for prevention of sympathetic stimulation. We report the successful application of general anesthesia for ICD implantation in a pediatric patient with ATS and recurrent VT.

• Mycobiology
• /
• 제40권4호
• /
• pp.236-243
• /
• 2012

Pleurotus nebrodensis is an edible and commercially available mushroom in Korea. This study was conducted in order to evaluate the anticancer and immunopotentiating activities of crude polysaccharides, extracted in methanol, neutral saline, and hot water (hereafter referred to as Fr. MeOH, Fr. NaCl, and Fr. HW, respectively) from the fruiting bodies of P. nebrodensis. ${\beta}$-Glucan and protein contents in Fr. MeOH, Fr. NaCl, and Fr. HW extracts of P. nebrodensis ranged from 23.79~36.63 g/100 g and 4.45~6.12 g/100 g, respectively. Crude polysaccharides were not cytotoxic against sarcoma 180, HT-29, NIH3T3, and RAW 264.7 cell lines at a range of $10{\sim}2,000{\mu}g/mL$. Intraperitoneal injection with crude polysaccharides resulted in a life prolongation effect of 11.76~27.06% in mice previously inoculated with sarcoma 180. Treatment with Fr. NaCl resulted in an increase in the numbers of spleen cells by 1.49 fold at the concentration of $50{\mu}g/mL$, compared with control. Fr. HW improved the immuno-potentiating activity of B lymphocytes through an increase in alkaline phosphatase activity by 1.65 fold, compared with control at $200{\mu}g/mL$. Maximum production of nitric oxide ($14.3{\mu}M$) was recorded in the Fr. NaCl fraction at $200{\mu}g/mL$. Production of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-$1{\beta}$ (IL-$1{\beta}$), and interleukin-6 (IL-6) was significantly higher, compared to control, and IL-6 production was highest, in contrast to TNF-${\alpha}$, IL-$1{\beta}$, and positive control, concanavalin at the tested concentration of the various fractions. Results of the current study suggest that polysaccharides extracted from P. nebrodensis have a strong anticancer effect and may be useful as an ingredient of biopharmaceutical products for treatment of cancer.

• Mycobiology
• /
• 제40권3호
• /
• pp.181-188
• /
• 2012

This study was initiated in order to investigate the anticancer and immunomodulating activities of crude polysaccharides extracted in methanol, neutral saline, and hot water (hereinafter referred to as Fr. MeOH, Fr. NaCl, and Fr. HW, respectively) from the fruiting bodies of Panellus serotinus. Content of ${\beta}$-glucan and protein in Fr. MeOH, Fr. NaCl, and Fr. HW extracts of P. serotinus ranged from 22.92~28.52 g/100 g and 3.24~3.68 g/100 g, respectively. In vitro cytotoxicity tests, none of the various fractions of crude polysaccharides were cytotoxic against sarcoma 180, HT-29, NIH3T3, and RAW 264.7 cell lines at the tested concentration. Intraperitoneal injection with crude polysaccharides resulted in a life prolongation effect of 23.53~44.71% in mice previously inoculated with sarcoma 180. Treatment with Fr. HW resulted in an increase in the numbers of spleen cells by 1.3 fold at the concentration of $50{\mu}g/mL$ compared with control. Treatment with Fr. NaCl resulted in improvement of the immuno-potentiating activity of B lymphocytes by increasing the alkaline phosphatase activity by 1.4 fold, compared with control, at the concentration of $200{\mu}g/mL$. Among the three fractions, maximum nitric oxide ($13.48{\mu}M$) was recorded at $500{\mu}g/mL$ in Fr. HW. Production of tumor necrosis factor alpha, interleukin-$1{\beta}$, and interleukin-6 was significantly higher, compared to the positive control, concanavalin A, at the tested concentration. Therefore, treatment with crude polysaccharides extracted from the fruiting body of P. serotinus could result in improvement of antitumor activity.