• 제목/요약/키워드: levels of evidence

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위험도 분석에 기반한 On-demand 방식의 호스트 침해 증거 자료 수집 방안 (On-demand Evidence Collection of Host Infringement based on the Analysis of Severity levels)

  • 최윤호;박종호;김상곤;서승우;강유;최진기;문호건;이명수
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2006년도 하계종합학술대회
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    • pp.33-34
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    • 2006
  • Computer Forensics is a research area which finds the malicious users by collecting and analyzing the intrusion or infringement evidence of the computer crime. Many research about Computer Forensics has been done. But those research have focussed on how to collect the evidence after receiving the damage reports from computer users or network administrators. This paper describes about collecting the evidence of good quality at the time of infringement occurrence by the malicious user. By calculating Infringement severity of observable and protective hosts and referring to this value, we collect the evidence at the time of infringement occurrence to minimize the information modification of the evidence. We can reduce also the amount of logs that we use to analyze the infringement and can minimize the loss of the evidence.

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갑상선암에서 혈청 Thyroglobulin치의 임상적 의의 (Clinical Significance of Serum Thyroglobulin Levels in Patients with Thyroid Cancer)

  • 박성기;이명식;이명철;조보연;김병국;고창순
    • 대한핵의학회지
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    • 제17권2호
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    • pp.41-47
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    • 1983
  • To evaluate the significance of assay of serum thyroglobulin(Tg) in monitoring the course of the thyroid cancer or its response to treatment, serum thyroglobulin levels were measured in 41 patients with thyroid cancer who visited Seoul National University Hospital from August, 1981 to August, 1982. The results were as follows: 1) Serum Tg levels $1\sim3$ months after thyroidectomy was $31{\pm}23$ ng/ml$(mean{\pm}S.D.)$ in 14 patients without metastasis, $66{\pm}41$ ng/ml in 21 patients with regional metastasis and $176{\pm}59$ ng/ml in 6 patients with distant metastasis and there were significant differences among three groups(p<0.01). 2) Serum Tg levels in 13 patients with metastasis before and after $^{131}I$ treatment were $134{\pm}62ng/ml$ and $67{\pm}52ng/ml$ respectively. 3) In the follow-up measurement of serum Tg levels every 3 months for about 1 year, almost all serum Tg levels were below 60 ng/ml in 12 patients without distant metastasis and serum Tg levels were elevated above 60 ng/ml in 5 of 6 patients with distant metastasis. 4) In 6 patients with distant metastasis, serum Tg levels were elevated in 5 patients and $^{131}I$ whole body scan showed definite metastatic evidence in 3 patients and suspicious evidence in 1 patient. From above results, we concluded that serum Tg level is very useful as an indicator of recurrence or metastasis in patients with thyroid cancer after operation.

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근거-기반의 신체활동사업 모니터링을 위한 정책 제안 (Policy proposal for monitoring of evidence-based physical activity projects)

  • 김완수;이미라
    • 보건교육건강증진학회지
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    • 제32권1호
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    • pp.67-76
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    • 2015
  • Objectives: This study performed to verify Korea National Health and Examination Survey(KNHAES) to monitor recommended physical activity(PA) and to propose an monitoring tools for evidence-based PA projects. Methods: The characteristics of the Global Physical Activity Questionnaire(GPAQ) and its reliability and validity were overviewed based on the current scientific evidence in the field of PA. Relevant articles were identified through multiple sources including PubMed, Science Direct, Scopus, CINAHL, ASP, RISS4U, and KISS. Results: The GPAQ has strong points over the Short Form of International Physical Activity Questionnaire(IPAQ-SF) as a monitoring tool to meet recommended PA levels for three domains separately and reflecting a better understanding about walking. Its reliability and validity also were reported as acceptable in existing studies overall. Some limitations of this questionnaire, however, need to be addressed to improve its quality. Conclusions: For monitoring of evidenced-based physical activity projects, we considered that it is able to be provided an opportunity for in-depth discussion among academic experts and policy-makers about the necessity of complements for KNHAES and applying new tools, and it could be the basis for development of physical activity monitoring tool in the future.

웹기반 체온 관리 근거중심 간호실무 가이드라인이 위절제술 환자의 체온, 전율, 체온 불편감, 체온 관리 만족도에 미치는 효과 (Use of Web-Based Evidence-based Clinical Practice Guidelines for Patients following Gastrectomy: Effects on Body Temperature, Shivering, Perceived Thermal Comfort, and Satisfaction with Temperature Management)

  • 홍성정;이은주
    • 기본간호학회지
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    • 제21권2호
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    • pp.112-122
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    • 2014
  • Purpose: The purpose of this study was to examine the effects on body temperature, shivering, and perceived thermal comfort of web-based evidence-based practice guideline for patients undergoing gastrectomy. Methods: Eighty patients scheduled for gastrectomy were recruited and assigned to the control or experimental group by sequential order. Before collecting data from the experimental group, a systematic educational program on evidence-based guidelines was provided to the nurses as well anesthesiologists. Data were analyzed using t-test and repeated measured ANOVA. Results: The experimental group showed higher body temperature from the induction of anesthesia until four hours after surgery compared to the control group. In addition, the levels of thermal comfort as well as satisfaction with thermal management were significantly higher in the experiment group. Conclusion: Use of evidence-based guidelines was effective in maintaining body temperature, lowering sensitivity to shivering, and promoting perceived thermal comfort. Therefore, adoption of evidence-based interventions in nursing practice is recommended.

Changes in Structural and Functional Responses of Bacterial Communities under Different Levels of Long-Term Compost Application in Paddy Soils

  • Samaddar, Sandipan;Han, Gwang Hyun;Chauhan, Puneet Singh;Chatterjee, Poulami;Jeon, Sunyoung;Sa, Tongmin
    • Journal of Microbiology and Biotechnology
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    • 제29권2호
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    • pp.292-296
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    • 2019
  • Soils amended for long-term with high levels of compost demonstrated greater abundance of bacterial members of the phylum Bacteroidetes whereas a decreasing trend in the relative abundance of phylum Acidobacteria was noted with increasing levels of compost. Metabolic profiles predicted by PICRUSt demonstrated differences in functional responses of the bacterial community according to the treatments. Soils amended with lower compost levels were characterized by abundance of genes encoding enzymes contributing to membrane transport and cell growth whereas genes encoding enzymes related to protein folding and transcription were enriched in soils amended with high levels of compost. Thus, the results of the current study provide extensive evidence of the influence of different compost levels on bacterial diversity and community structure in paddy soils.

Is aromatherapy associated with patient's dental anxiety levels? A systematic review and meta-analysis

  • Purohit, Abhishek;Singh, Abhinav;Purohit, Bharathi;Shakti, Prateek;Shah, Nidhi
    • Journal of Dental Anesthesia and Pain Medicine
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    • 제21권4호
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    • pp.311-319
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    • 2021
  • The use of aromatherapy for the reduction of anxiety levels during dental treatment procedures has been well established in the literature; however, there is limited evidence regarding its efficacy. The present meta-analysis is an attempt to assess the association between the use of aromatherapy and anxiety levels among dental patients. A comprehensive search was conducted across Medline, Scopus, Web of Science, EBSCO host, Cochrane databases, and Google Scholar for studies evaluating aromatherapy and anxiety level among dental patients. PRISMA guidelines were followed for the meta-analysis. Randomized and cluster-randomized trials comparing aromatherapy with controls were included. The random-effects model was used to assess the mean differences in anxiety levels of patients visiting dental OPD. The significance value was set at P < 0.05. Six studies were identified that met the requirements for inclusion. Aromatherapy was significantly associated with reduction in patient anxiety levels during dental treatment (pooled mean difference: -3.36 [95% CI, -3.77 - -2.95, P = 0.00001). Low heterogeneity was noted between studies (I2 = 1%, P = 0.41) analyzed in the meta-analysis. High certainty of the evidence was obtained from the association between the use of aromatherapy and dental anxiety. This meta-analysis suggests that aromatherapy is effective in reducing dental anxiety. When used judiciously, the results of this work should encourage the use of aromatherapy to reduce patient anxiety levels during dental procedures

A Review of Scientific Evidence on Indoor Air of School Building: Pollutants, Sources, Health Effects and Management

  • Chithra, V.S;Shiva, Nagendra S.M
    • Asian Journal of Atmospheric Environment
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    • 제12권2호
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    • pp.87-108
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    • 2018
  • Schools are one of the critical social infrastructures in a society, the first place for social activity and the most important indoor environment for children besides the home. Poor IAQ in classrooms can increase the chance of long-term and short-term health problems for students and staffs; affects productivity of teachers; and degrade the student learning environment and comfort levels. The primary objective of this paper is to review and summarize available scientific evidence on indoor air quality of schools and related health effects in children. It was found that the indoor air pollutant levels in school buildings varied over a wide range in different parts of the world depending on site characteristics, climatic conditions, outdoor pollution levels, occupant activities, ventilation type and building practices. Among the indoor air pollutants, particulate matter concentrations were found to be very high in many schools. Outdoor pollutant sources also play a major role in affecting the IAQ of the school building. Hence, scientific knowledge on sources of indoor pollutants, quantification of emissions, temporal and spatial dispersion of pollutants, toxicological properties, chemical and morphological characteristics of the pollutants and associated health risk among children in the school buildings are essential to evaluate the adequacy and cost effectiveness of control strategies for mitigating the IAQ issues.

In Search for a Common Pathway for Health Issues in Men - the Sign of a Holmesian Deduction

  • Aoun, Fouad;Chemaly, Anthony Kallas;Albisinni, Simone;Zanaty, Marc;Roumeguere, Thierry
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권1호
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    • pp.1-13
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    • 2016
  • The evidence for the existence of a common pathway for health issues in men is presented in this review. Several epidemiological studies have shown that conditions like cardiovascular diseases (CVD), metabolic syndrome, diabetes, lower urinary tract symptom (LUTS), erectile dysfunction (ED), prostate cancer, hypogonadism, depression and suicide can be associated as risk factors for each other. Thus, the risk of CVD is significantly increased in men with metabolic syndrome, ED, hypogonadism, prostate cancer and/or LUTS. In addition, the above mentioned conditions are more prevalent in atherosclerotic patients. In addition, growing evidence indicates that low androgen levels can cause metabolic syndrome. In addition, obesity, dyslipidaemia and diabetes can further reduce androgen levels potentiating their adverse effect. Low testosterone levels are also associated with a higher incidence of aggressive prostate cancer on biopsy and on definitive pathology, and lower probability of abiraterone response in the metastatic setting. Several recent studies point towards diffuse endothelial dysfunction and dysregulated pro-inflammatory state as the biological link between all these disorders. Our current hypothesis is that oxidative stress caused by these dysfunctions explains the pathogenesis of each of these conditions.

Evidence and suggestions for establishing vitamin D intake standards in Koreans for the prevention of chronic diseases

  • Kim, Jung Hyun;Park, Hyoung Su;Pae, Munkyong;Park, Kyung Hee;Kwon, Oran
    • Nutrition Research and Practice
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    • 제16권sup1호
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    • pp.57-69
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    • 2022
  • BACKGROUND/OBJECTIVES: Vitamin D is produced in the skin during sun exposure and is also ingested from foods. The role of vitamin D needs to be considered in the prevention and management of various diseases. Moreover, since the majority of Koreans spend their days indoors, becoming susceptible to the risk of vitamin D deficiency. The current study aims to prepare a basis for determining dietary reference intake of vitamin D in Korea, by reviewing the evidence against various diseases and risks. MATERIALS/METHODS: Literature published in Korea and other countries between 2014 and 2018 was prioritized based on their study design and other criteria, and evaluated using the RoB 2.0 assessment form and United States Department of Agriculture Nutrition Evidence Library Conclusion Statement Evaluation Criteria. RESULTS: Of the 1,709 studies, 128 studies were included in the final systematic analysis after screening. To set the dietary reference intakes of vitamin D based on the selected articles, blood 25(OH)D levels and indicators of bone health were used collectively. Blood vitamin D levels and ultraviolet (UV) exposure time derived from the Korean National Health and Nutrition Examination Survey were analyzed to establish the dietary reference intakes of vitamin D for each stage of the life cycle. The adequate intake levels of vitamin D, according to age and gender, were determined to be in the range of 5-15 ㎍/day, and the tolerable upper intake level was established at 25-100 ㎍/day. CONCLUSIONS: The most important variable for vitamin D nutrition is lifestyle. A balanced diet comprising foods with high contents of vitamin D is important, as is vitamin D synthesis after UV exposure. The adequate intake level of vitamin D mentioned in the 2015 Dietary Reference Intakes for Korean (KDRI) remained unchanged in the 2020 KDRI for the management of vitamin D nutrition in Koreans.

Vitamin D Deficiency and Comorbidities as Risk Factors of COVID-19 Infection: A Systematic Review and Meta-analysis

  • Mishra, Pinki;Parveen, Rizwana;Bajpai, Ram;Agarwal, Nidhi
    • Journal of Preventive Medicine and Public Health
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    • 제55권4호
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    • pp.321-333
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    • 2022
  • Objectives: Extensive evidence links low vitamin D status and comorbidities with coronavirus disease 2019 (COVID-19) outcomes, but the results of published studies are contradictory. Therefore, we investigated the association of lower levels of vitamin D and comorbidities with the risk of COVID-19 infection. Methods: We searched MEDLINE (via PubMed), Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov for articles published until August 20, 2021. Sixteen eligible studies were identified (386 631 patients, of whom 181 114 were male). We included observational cohort and case-control studies that evaluated serum levels of vitamin D in COVID-19-positive and COVID-19-negative patients. Mean differences (MDs) with 95% confidence intervals (CIs) were calculated. Results: Significantly lower vitamin D levels were found in COVID-19-positive patients (MD, -1.70; 95% CI, -2.74 to -0.66; p=0.001), but with variation by study design (case-control: -4.04; 95% CI, -5.98 to -2.10; p<0.001; cohort: -0.39; 95% CI, -1.62 to 0.84; p=0.538). This relationship was more prominent in female patients (MD, -2.18; 95% CI, -4.08 to -0.28; p=0.024) than in male patients (MD, -1.74; 95% CI, -3.79 to 0.31; p=0.096). Male patients showed higher odds of having low vitamin D levels (odds ratio [OR], 2.09; 95% CI, 1.38 to 3.17; p<0.001) than female patients (OR, 1.17; 95% CI, 0.74 to 1.86; p=0.477). Comorbidities showed inconsistent, but generally nonsignificant, associations with COVID-19 infection. Conclusions: Low serum vitamin-D levels were significantly associated with the risk of COVID-19 infection. This relationship was stronger in female than in male COVID-19 patients. Limited evidence was found for the relationships between comorbidities and COVID-19 infection, warranting large population-based studies to clarify these associations.