• Journal of Community Nutrition
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• v.1 no.2
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• pp.88-97
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• 1999

The purpose of this study was to investigate the nutritional status of serum minerals, ceruloplasmin, and ferroxidase activity in female adolescent students according to their smoking status. The subjects were 87 non-smokers and 88 smokers, who were female high school students. The smokers were divided into tow groups by smoking status, 35 light smokers(pack-year<1) and 53 smokers(pack-year$\geq$1). The serum concentrations of 6 minerals were determined by ICP emission spectroanalyzer. The serum concentration of ceruloplasmin and ceruloplasmin ferroxidase activity were determined. All data were statistically analyzed by SAS PC package program. The serum minerals concentrations of all subjects were in a normal range. There were significantly differences in the concentrations of serum copper, zinc, magnesium, and phosphorus by smoking status while there were no significant differences in the concentrations of serum iron and manganese by smoking status. Furthermore there were no significant differences in the ceruloplasmin concentration and ferroxidase activity by smoking status. In conclusion, smoking status altered the serum levels of some minerals in healthy young women. The minerals levels in light smokers with relatively short pack-year(pack-year<1) were altered compared to those in non-smokers or smokers. This finding seemed to be consistent with the results of previously published data related to antioxidant vitamin and lipid peroxide levels. However further research is needed to clarify these findings in female adolescent smokers.

• Korean Journal of Organic Agriculture
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• v.27 no.4
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• pp.529-540
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• 2019

The present study investigated the effect of forage sources and their inclusion levels in diet on the rumen fermentation of Korea traditional goat. Timothy and alfalfa were used as forage sources. Forages were mixed with concentrate diet in different ratios. The ratios of forage to concentrate diets were varied to 1:9, 5:5 and 9:1. The rumen fluid of goat was gathered from slaughter house. Dry matter digestibility was decreased and methane production was increased as forage levels in diet was increased. When forage sources, timothy and alfalfa, were compared, groups with timothy showed greater methane production than the groups of alfalfa. Molar ratio of produced acetate and valerate were increased when forage level in diet was increased. In the case of propionate and butyrate, they were decreased as elevated forage levels in diet. The result of this study provided a basic information for rumen fermentation of Korean traditional goat and these information could be applied in the development of nutritional and feeding strategy.

• Clinical and Experimental Pediatrics
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• v.57 no.5
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• pp.211-216
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• 2014

Asthma comprises a heterogeneous group of disorders characterized by airway inflammation, airway obstruction, and airway hyperresponsiveness (AHR). Airway inflammation, which induces AHR and recurrence of asthma, is the main pathophysiology of asthma. The fractional exhaled nitric oxide (FeNO) level is a noninvasive, reproducible measurement of eosinophilic airway inflammation that is easy to perform in young children. As airway inflammation precedes asthma attacks and airway obstruction, elevated FeNO levels may be useful as predictive markers for risk of recurrence of asthma. This review discusses FeNO measurements among early-childhood wheezing phenotypes that have been identified in large-scale longitudinal studies. These wheezing phenotypes are classified into three to six categories based on the onset and persistence of wheezing from birth to later childhood. Each phenotype has characteristic findings for atopic sensitization, lung function, AHR, or FeNO. For example, in one birth cohort study, children with asthma and persistent wheezing at 7 years had higher FeNO levels at 4 years compared to children without wheezing, which suggested that FeNO could be a predictive marker for later development of asthma. Preschool-aged children with recurrent wheezing and stringent asthma predictive indices also had higher FeNO levels in the first 4 years of life compared to children with wheezing and loose indices or children with no wheeze, suggesting that FeNO measurements may provide an additional parameter for predicting persistent wheezing in preschool children. Additional large-scale longitudinal studies are required to establish cutoff levels for FeNO as a risk factor for persistent asthma.

• The Korean Journal of Health Service Management
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• v.13 no.3
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• pp.93-103
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• 2019

Objectives: The purpose of this study was to analyze the association between health status and physical activity levels in older adults (over 65 years) in Korea. Methods: The participants were selected from the database of the Seventh Korea National Health and Nutrition Examination Survey (KNHANES VII), conducted by the Korea Centers for Disease Control and Prevention in 2017. A chi-square test and logistic regression analysis were used to analyze data. Results: The findings showed that health conditions such as hypertension and diabetes were related to physical activity levels of the older adults. In addition to health status, social and economic factors such as gender, age, and geographic region should be considered in order to initiate the practice of aerobic and strength exercise in the older adults. Conclusions: To initiate physical activity levels in the older adults, it is necessary to consider support for costs involved, policies required for the development of integrated exercise programs, expansion of public exercise facilities, and improved facilities.

• Smart Structures and Systems
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• v.24 no.4
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• pp.525-539
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• 2019

In this study, vibration characteristics of a gravity-based caisson-foundation breakwater system are investigated for ambient and geometric parameters such as various waves, sea levels, and foundation conditions. To achieve the objective, following approaches are implemented. Firstly, operational modal analysis methods are selected to identify vibration modes from output-only dynamic responses. Secondly, a finite element model of an existing caisson-foundation breakwater system is established by using a structural analysis program, ANSYS. Thirdly, forced vibration analyses are performed on the caisson-foundation system for two types of external forces such as controlled impacts and wave-induced dynamic pressures. For the ideal impact, the wave force is converted to a triangular impulse function. For the wave flow, the wave pressure acting on the system is obtained from wave field analysis. Fourthly, vibration modes of the caisson-foundation system are identified from the forced vibration responses by combined use of the operational modal analysis methods. Finally, vibration characteristics of the caisson-foundation system are investigated under various waves, sea levels, and foundations. Relative effects of foundation conditions on vibration characteristics are distinguished from that induced by waves and sea levels.

• BMB Reports
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• v.40 no.2
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• pp.142-150
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• 2007

Epigenetic alterations, represented by aberrant DNA methylation, are deeply involved in human cancers. In gastric cancers, tumor-suppressor genes are inactivated more frequently by promoter methylation than by mutations. We recently showed that H. pylori infection, a potent gastric carcinogenic factor, induces methylation of specific genes in the gastric mucosae. When the methylation levels were analyzed in the gastric mucosae of healthy volunteers, cases with a single gastric cancer, and cases with multiple gastric cancers, who have increasing levels of risks for gastric cancers, there was a significant increasing trend in the methylation levels among the individuals without current H. pylori infection. This finding unequivocally showed the presence of an epigenetic field for cancerization. The degree of the field defect was measured more conveniently using methylation levels of marker genes than using those of tumor-suppressor genes. The presence of an epigenetic field for cancerization has been indicated for liver, colon, Barrett's esophageal, lung, breast, and renal cancers. Since decreased transcription is involved in the specificity of methylated genes, it is likely that specific genes are methylated according to carcinogenic factors. These findings emphasize the usefulness of DNA methylation as a marker for past exposure to carcinogens and future risk of cancer development.

• Educational Technology International
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• v.18 no.2
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• pp.159-191
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• 2017

Academic analytics guides university decision-makers to assign limited resources more effectively. Especially, diverse academic courses clustered by the usage patterns and levels on Learning Management System(LMS) help understanding instructors' pedagogical approach and the integration level of technologies. Further, the clustering results can contribute deciding proper range and levels of financial and technical supports. However, in spite of diverse analytic methodologies, clustering analysis methods often provide different results. The purpose of this study is to present implications by using three different clustering analysis including Gaussian Mixture Model, K-Means clustering, and Hierarchical clustering. As a case, we have clustered academic courses based on the usage levels and patterns of LMS in higher education using those three clustering techniques. In this study, 2,639 courses opened during 2013 fall semester in a large private university located in South Korea were analyzed with 13 observation variables that represent the characteristics of academic courses. The results of analysis show that the strengths and weakness of each clustering analysis and suggest that academic leaders and university staff should look into the usage levels and patterns of LMS with more elaborated view and take an integrated approach with different analytic methods for their strategic decision on development of LMS.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2005.05a
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• pp.535-540
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• 2005

In environmental impact assessment, noise impact assessment usually consists of three stages surveying the existing noise levels by measurements, predicting noise levels induced by construction works and predicting noise levels after the completion of project. When predicting noise level in urban area, this method does not consider acoustic phenomena like multi reflection, diffraction and absorption due to complex topographic configuration of building and terrains. For the purpose, a noise mapping tool is utilized to produce a series of noise maps, which are those for the present, for the works of construction and for the future. For accurate noise mapping, acoustical and topographic information is essential. Standard sound power levels and directivities of various construction equipments are required and scheduling of construction processes and locations of the equipments should be provided. In the case of exceeding legal limit, mitigation measures are applied to satisfy the legal limits and subsequent noise map is obtained and checked.

• Journal of Korean language education
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• v.28 no.1
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• pp.221-250
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• 2017

This study aims to discuss the basic foundations to set levels and language skills for developing a Korean Proficiency Test for young and adolescent learners. Recently, there has been an increase in demand regarding young and adolescent learners from multicultural and overseas backgrounds. However, the current Korean Proficiency Test lacks the appropriate means to determine the Korean proficiency of young and adolescent learners with general purposes of language learning. Therefore, there is an urgent need for developing a specialized and new form of language assessment for young and adolescent learners who are exposed to a foreign language or a second language learning environment. The study examines and analyzes cases of foreign language examinations for young & adolescent learners; furthermore, the objectives and target were set based on the results of a needs analysis and in-depth interviews conducted among teachers and education officials in overseas Korean Hangeul Schools, international schools, elementary and secondary schools. Finally, the levels and language skills appropriate for the objectives of a proficiency test and target learners have been suggested.

• Journal of the Korean Society of Physical Medicine
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• v.19 no.3
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• pp.47-54
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• 2024

PURPOSE: This study aimed to identify the potential clinically predictive indicators of the age-related loss of skeletal muscle mass (ALSMM) in middle-aged women. METHODS: The data from a cross-sectional study involving 2,066 community-dwelling female participants aged 40 to 49 years were analyzed. Complex sampling analyses were used to ensure a nationally representative analysis, incorporating the individual weights provided by KNHANES. This approach accounted for the stratified, clustered, and multistage probability sampling design of the survey. The participants were screened for ALSMM, and various potential predictive indicators were assessed, including age, height, weight, body mass index, waist circumference, skeletal muscle mass index, smoking and drinking status, systolic and diastolic blood pressure, fasting glucose levels, triglyceride levels, and cholesterol levels. RESULTS: Significant potential predictive indicators for ALSMM included height, weight, body mass index, waist circumference, skeletal muscle mass index, and fasting glucose (p < .05). The systolic blood pressure, diastolic blood pressure, triglyceride levels triglyceride, and drinking and smoking status were found to be non-significant variables (p > .05). CONCLUSION: The study identified the potential predictive indicators for ALSMM among community-dwelling middle-aged women. These findings enhance the current understanding of ALSMM and highlight the potential predictive indicators associated with its development in middle-aged women.