• Title/Summary/Keyword: levels of development

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Pathways from Interparental Conflict to Adolescents' Problem Behavior through Maternal Support and Control and Quality of Peer Relationships (부모간 갈등, 어머니의 지지 및 통제와 또래관계의 질이 고등학생의 문제행동에 영향을 미치는 경로)

  • Cho, Joo-Yon;Doh, Hyun-Sim
    • Korean Journal of Child Studies
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    • v.32 no.2
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    • pp.15-34
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    • 2011
  • The main purpose of this study was to examine pathways from interparental conflict to adolescents' problem behavior through maternal support and control and/or quality of peer relationship. A sample of 340 high school students (166 boys and 174 girls) in Incheon completed questionnaires on interparental conflict, maternal support and control, quality of peer relationship, and problem behavior. Data were analyzed by means of structural equation modeling. The results demonstrated that interparental conflict had a direct influence in both internalizing and externalizing problem behaviors, indicating that adolescents who perceived higher levels of interparental conflict had more problem behaviors. Regarding pathways from interparental conflict to problem behavior through maternal support and control and/or quality of peer relationships, adolescents perceiving higher levels of interparental conflict reported higher maternal psychological control and lower support and behavioral control. This was followed by a lower level of quality in terms of their peer relationships; the lower quality of peer relationships resulted in more adolescent problem behaviors. These results indicate that interparental conflict and maternal support and control play crucial roles in the development of internalizing and externalizing problem behavior, respectively.

Effect of Oxybenzone (Benzophenone-3) on Rock Bream Oplegnathus fasciatus, Embryo Development (옥시벤존(Benzophenone-3)이 돌돔(Oplegnathus fasciatus)의 배 발생 과정에 미치는 영향)

  • Song, Mihae;Baek, Hea Ja
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.55 no.4
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    • pp.455-460
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    • 2022
  • Oxybenzone (Benzophenone-3; BP-3) is a compound used in sunscreens and enters the oceans due to improper disposal. It is known to disrupt the endocrine signaling in marine organisms, leading to immune and reproductive abnormalities in corals, shellfish and fishes. In this study, we investigated the effects of different concentrations of BP-3 (0, 10, 100 and 1,000 ㎍/L) on the fertilized eggs and hatched larvae of Oplegnathus fasciatus. The morphological changes and hatching and survival rates during embryo development were assessed. In addition, the levels of triiodothyronine (T3) were also measured. The hatched larvae exposed to BP-3 at concentrations of 10 and 100 ㎍/L for 24 h displayed malformation of the tail. After 36 h of exposure to BP-3, spinal deformity was observed at all tested concentrations. The hatching rate was significantly low when exposed to 100 ㎍/L of BP-3. A high levels of T3 was observed when the larvae were exposed to BP-3 at a concentration of 1,000 ㎍/L for 96 h (the end of the experiment). This may be related to increased size of larvae at 1,000 ㎍/L BP-3. In conclusion, our results suggested that BP-3 may interfere with embryo development, resulting in a reduction in hatching rate and malformation of larvae.

Effects of (-)-Epicatechin Gallate on porcine oocyte in vitro maturation and subsequent embryonic development after parthenogenetic activation and in vitro fertilization

  • Seo, Min-Su;So, Kyoung-Ha;Hyun, Sang-Hwan
    • Journal of Embryo Transfer
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    • v.31 no.3
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    • pp.153-159
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    • 2016
  • (-)-Epicatechin gallate (ECG) is a polyphenol compound of green tea exhibiting biological activities, such as antioxidant and anticancer effects. To examine the effect of ECG on porcine oocytes during in vitro maturation (IVM), oocytes were treated with 0-, 5-, 15-, and $25{\mu}M$ ECG. After maturation, we investigated nuclear maturation, intracellular glutathione (GSH) and reactive oxygen species (ROS) levels and subsequent embryonic development after parthenogenetic activation (PA) and in vitro fertilization (IVF). After 42 hours of IVM, the $5{\mu}M$ group exhibited significantly increased (p< 0.05) nuclear maturation (89.8%) compared with the control group (86.1%). However, the $25{\mu}M$ group observed significantly decreased (p< 0.05) nuclear maturation (83.5%). In intracellular maturation assessment the 5-, 15-, and $25{\mu}M$ groups had significantly increased (p< 0.05) GSH levels and decreased ROS levels compared with the controls. The 5- and $15{\mu}M$ group showed significantly increased (p< 0.05) embryo formation rates and total cell number of blastocysts after PA (18% and 68.9, 15% and 85.1 vs. 12% and 59.5, respectively) compared with controls. Although the $25{\mu}M$ group observed significantly lower blastocyst formation rates after PA (27.6% vs. 23.2%) than control group, the $5{\mu}M$ group showed significantly increased blastocyst formation rates after PA (37.2% vs. 23.2%) compared to the control group. Furthermore, the $5{\mu}M$ group measured significantly increased blastocyst formation rates (20.7% vs. 8.6%) and total cell number after IVF ($88.3{\pm}1.5$ vs. $58.0{\pm}3.6$) compared to the control group. The treatment of $5{\mu}M$ ECG during IVM affectively improved the porcine embryonic developmental competence by regulating intracellular oxidative stress during IVM.

Effect of Fertilizer Levels on Growth Characters, Dry Matter Yield and Nutrient Quality of Forage Rape in Spring Sowing

  • Kwon, Byung-Sun;Shin, Jeong-Sik;Shin, Dong-Young;Hyun, Kyu-Hwan;Park, Hee-Jin;Sin, Jong-Sup;Seong-Kyu
    • Plant Resources
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    • v.6 no.2
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    • pp.102-107
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    • 2003
  • To find out the optimum fertilizer level for high yielding variety, Velox, experiment was conducted with 15 compositions of fertilizer levels at the experiment field of forage crop in Sunchon National University from Mar. 2000 to Aug. 2000. The effects of nitrogen fertilizer on plant growth were significant but increasing rate of application in potassium and phosphate fertilizers above 6 kg/a had negligible effects on plant growth. The optimum nitrogen application level of fertilizers turned out to be 16-6-6 kg/l0a of N-P$_2$O$_{5}$-K$_{5}$O. Content of crude protein was highest and that of crude fiber such as NDF, ADF, cellulose and lignin were lowest at this rate of fertilizer application. Furthermore, IVDMD was high and dry matter yield were highest at the optimum raterate

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Histological Changes of Oocytes Development and Hormone Levels in the Israeli carp (Cyprinus carpio) from February to May (2~5월 사이의 이스라엘 잉어(Cyprinus carpio) 난모세포의 조직학적 변화 및 호르몬 수준의 변화)

  • Lee Jae-Hyun;Yoon Jong-Man;Park Hong-Yang
    • Journal of Aquaculture
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    • v.2 no.1
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    • pp.21-32
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    • 1989
  • This study was undertaken to understand development stage of ovary and changes of hormone concentrations in the Israeli carp, Cyprinus carpio from Ferbruary to May. The results obtained in these experiments are as follows: 1. Serum LH levels began to increase sharply in March, coinciding with the onset of rapid ovarian development. 2. LH levels were well correlated with changes in gonadosomatic index. 3. Dramatic increase in gonadosomatic index occured during the months of March. 4. Ripe stage(Stage VII) rapidly increase in March. 5. Early perinucleolus oocyte rapidly develop into late perinucleolus oocytes in March. 6. The vitellogenic phase begins as these late perinucleolus oocytes become transformed into early maturing oocytes through the accumulation of yolk. 7. The cytoplasm completely fills with yolk as oocytes reach the late maturing stage. 8. Changes in the microscopic appearances of the ovaries were well correlated with changes in both gonadosomatic index and macroscopic appearance. 9. It is concluded from these observations that LH plays a major role in sexual maturating of the Israeli carp.

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Effect of Blanching Time on Changes of Hazardous Factors in Leafy Vegetables Treated by Pesticides (데치는 시간이 침투성 및 비침투성 농약 처리 엽채류의 위해성 요인 변화에 미치는 영향)

  • Ah Taehyun;Chun Hye-Kyung;Hong Jeong-Jin
    • Korean journal of food and cookery science
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    • v.21 no.2 s.86
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    • pp.201-208
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    • 2005
  • This study was conducted to investigate the effect of blanching time on changes of hazardous factors in leafy vegetables treated by systemic and non-systemic pesticides. Changes of hazardous factors in leafy vegetables treated by systemic and non-systemic pesticides showed the same trend. In changes of microbial counts in leafy vegetables according to blanching time, the total plate count was significantly decreased by blanching and total coliforms were not detected in any of the vegetables. In traceable metal contents of fresh vegetables before washing, the levels in spinach, chard and whorled mallow were 0.042, 0.040 and 0.032 ppm for Pb, 0.020, 0.023 and 0.019 ppm for Cd, and 0.029, 0.034 and 0.030 ppm for As, respectively. Therefore, the levels of Pb, Cd and As in leafy vegetables were very traceable and in terms of food safety there was no problem. On the other hand, the traceable metal contents in leafy vegetables did not show significant difference by blanching and blanching time. Nitrate contents in fresh vegetables before washing were detected at traceable levels. The nitrate contents in spinach, chard and whorled mallow were significantly decreased by $22\%,\;17\%\;and\;14\%$ after blanching time of 5 min, 9 min and 10 min, respectively.

Anti-hyperglycemic Effect of Bangpungtongseong-san on Type II Diabetes Animal Models (제2형 당뇨 동물모델을 이용한 방풍통성산의 고혈당 개선효과)

  • Ko, Moon Hee;Cho, Hyun Woo;Nho, Jong Hyun
    • Korean Journal of Medicinal Crop Science
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    • v.28 no.4
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    • pp.287-297
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    • 2020
  • Background: Type II diabetes is considered as one of the common diseases. Bangpungtongseongsan (BPS) has been used as a traditional medicine for treating obesity and hypertension in Korea. According to previous reports, it has anti-obesity, anti-chronic asthma, anti-oxidant, and anti-inflammatory properties. However, the effects of BPS on type II diabetes have not yet been elucidated. Thus, in this sutudy, we evaluated the water extracts of BPS using type II diabetes animal models. Methods and Results: Each group was orally administered with BPS (170, 850 and 1,700 mg/kg) for approximately 13 weeks. A mixture of 150 mg/kg metformin and 10 mg/kg sitagliptin (MS) was used as a positive control. The glycated hemoglobin (HbA1c) and glucose levels, and hematological parameters including blood urine nitrogen, creatinine, low density lipoprotein and total cholesterol, were measured using blood samples. Treatment with 170 mg/kg BPS decreased the HbA1c and glucose levels in blood without affecting the weights of the animals. However, threatment with 1,700 mg/kg BPS reduced the weights and fatty liver, and increased the blood glucose level in type II diabetes animal models Conclusions: These results indicate that a low dose of BPS for 13 weeks, which reduces HbA1c and blood glucose levels, could be used for the treatment of type II diabetes. However, further studies are required to elucidate how active ingredients of BPS influence HbA1c and glucose levels in blood.

The path analysis of carbon emission reduction: A case study of the Silk Road Economic Belt

  • Kong, Yang;He, Weijun
    • Environmental Engineering Research
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    • v.25 no.1
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    • pp.71-79
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    • 2020
  • This paper uses super-efficiency DEA model and Malmquist index to evaluate the carbon emission efficiency (CEE) values of the nine western provinces along the "Silk Road Economic Belt" for the period from 2000 to 2015, and analyses the influencing factors of the CEE. The major findings of this study are the following: (1) the overall CEE of the nine western provinces is not high, and there are significant inter-provincial differences in the CEE. Meanwhile, the provinces with higher levels of economic development generally have higher CEE. (2) The annual total factor productivity (TFP) of the nine western provinces, which is mainly determined by technological change, is greater than 1. Moreover, the total average growth rate of the TFP is 15.5%. (3) The CEE of the nine western provinces is not spatially dependent. In addition, the urbanization, openness, use of energy-saving technologies and research and development (R&D) investment have a significant positive impact on the CEE values, while the industrial structure, foreign direct investment, fixed asset investment, government expenditure levels and energy structure have a significant negative impact on the CEE. Among them, R&D investment is the primary factor in promoting the development of CEE, and the government expenditure has the greatest negative impact on the CEE.

NOX4 and its association with myeloperoxidase and osteopontin in regulating endochondral ossification

  • Kayoung Ko;Seohee Choi;Miri Jo;Chaeyoung Kim;Napissara Boonpraman;Jihyun Youm;Sun Shin Yi
    • Journal of Veterinary Science
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    • v.25 no.4
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    • pp.49.1-49.15
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    • 2024
  • Importance: Endochondral ossification plays an important role in skeletal development. Recent studies have suggested a link between increased intracellular reactive oxygen species (ROS) and skeletal disorders. Moreover, previous studies have revealed that increasing the levels of myeloperoxidase (MPO) and osteopontin (OPN) while inhibiting NADPH oxidase 4 (NOX4) can enhance bone growth. This investigation provides further evidence by showing a direct link between NOX4 and MPO, OPN in bone function. Objective: This study investigates NOX4, an enzyme producing hydrogen peroxide, in endochondral ossification and bone remodeling. NOX4's role in osteoblast formation and osteogenic signaling pathways is explored. Methods: Using NOX4-deficient (NOX4-/-) and ovariectomized (OVX) mice, we identify NOX4's potential mediators in bone maturation. Results: NOX4-/- mice displayed significant differences in bone mass and structure. Compared to the normal Control and OVX groups. Hematoxylin and eosin staining showed NOX4-/- mice had the highest trabecular bone volume, while OVX had the lowest. Proteomic analysis revealed significantly elevated MPO and OPN levels in bone marrow-derived cells in NOX4-/- mice. Immunohistochemistry confirmed increased MPO, OPN, and collagen II (COLII) near the epiphyseal plate. Collagen and chondrogenesis analysis supported enhanced bone development in NOX4-/- mice. Conclusions and Relevance: Our results emphasize NOX4's significance in bone morphology, mesenchymal stem cell proteomics, immunohistochemistry, collagen levels, and chondrogenesis. NOX4 deficiency enhances bone development and endochondral ossification, potentially through increased MPO, OPN, and COLII expression. These findings suggest therapeutic implications for skeletal disorders.

Investigating Ways of Developed and Undeveloped Features from Satellite Images -Balancing Coastal Development and Preservation- (위성영상을 이용한 개발과 미개발 지역의 구분을 위한 탐색적 방법)

  • Yang, Byung-Yun
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.30 no.2
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    • pp.189-197
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    • 2012
  • This research attempted to find possibilities of the practical use utilizing geospatial methods for the balanced promotion of sustainable coastal development and preservation through a case study of Jekyll Island, one of Georgia's barrier islands. In response, this research provided ways for practical use in sustainable development and preservation plans. First this research thoroughly investigated the 1996 master plan of Jekyll Island and tried to recalculate developed and undeveloped areas. Second, new estimations for developed areas were investigated through field survey. Third, this research proposed the use of the satellite images with different levels of spatial resolutions and tested different classification schemes to find possibilities for practical use. For these purposes, first, we classified developed and undeveloped features by manual digitization using an aerial photo image with 0.5m spatial resolution. Second, a Landsat 7 ETM+ and a QuickBird satellite images with mid- and high-levels of spatial resolutions were applied to identify developed and undeveloped areas using both the National Land Cover Data (NLCD) and the Coastal Change Analysis Program (CCAP) classification schemes. Also, GEOBIA (Geographic Object-Based Image Analysis) was conducted to accurately identify developed and undeveloped areas.