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Effect of Dietary Coenzyme $Q_10$ on Lipid Peroxidation in Adriamycin-treated Rats - I. Effect on Lipid Peroxide Metabolizing Enzyme Activities- (식이 중의 Coenzyme $Q_10$첨가가 Adriamycin을 투여한 흰쥐의 체내 지질과산화에 미치는 영향- 1. 지질과산화물 대사효소에 미치는 영향-)

  • 서정숙;한인규
    • Journal of Nutrition and Health
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    • v.24 no.3
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    • pp.166-178
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    • 1991
  • This present study was designed to evaluate whether supplementaion of dietary coenzyme $Q_{10}$ protects the lipid peroxidation damage in adriamycin (ADR)-treated rats. Two experiments were conducted in this study. Experiment I was undertaken under the condition of simultaneous administration of ADR and coenzyme $Q_{10}$ for 4 weeks. Experiment 2 was undertaken under the same condition as experiment I after feeding the experimetal diets alone without administration of ADR for 4 weeks. Results obtained from the present study were as follows. Lipid peroxide value of plasma and heart mitochondria was elevated by ADR treatment. but decreased according to dietary coenzyme $Q_{10}$ supplementation. Pretreatment with dietary coenzyme $Q_{10}$ was more efficient in reducing ADR-induced lipid peroxide value. The simultaneous use of ADR and coenzyme $Q_{10}$ enhanced the heart glutathione peroxidase (GSH-Px) activity. particularly at higher level of coenzyme $Q_{10.}$ The change of superoxide dismutase(SOD) activity was similar to that of GSH-Px activity. In case of pretreatment with coenzyme $Q_{10, }$ these enzyme activities were more enhanced by dietary coenzyme $Q_{10.}$ However, there was little difference in catalase activity.

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Estimation of Urban Heat Island Potential Based on Land Cover Type in Busan Using Landsat-7 ETM+ and AWS Data (Landsat-7 ETM+ 영상과 AWS 자료를 이용한 부산의 토지피복에 따른 여름철 도시열섬포텐셜 산출)

  • Ahn, Ji-Suk;Hwang, Jae-Dong;Park, Myung-Hee;Suh, Young-Sang
    • Journal of the Korean Association of Geographic Information Studies
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    • v.15 no.4
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    • pp.65-77
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    • 2012
  • This study examined changes in land cover for the past 25 years in Busan and subsequently evaluated heat island potential by using land surface temperature and observation temperature data. The results were as below. The urban area of Busan increased by more than 2.5 times for the past 25 years from 1975 to 2000. It was believed that an increase in the pavement area of city within such a short period of time was an unprecedented phenomenon unique to our country. It could be assumed that urban heat island would be worsened through this process. After analyzing the land temperature according to the land cover, it was shown that there were noticeable changes in the temperature of urban & built-up and mountain & forest areas. In particular, the temperature rose to $36{\sim}39^{\circ}C$ in industrial areas during the summer, whereas it went down to $22{\sim}24^{\circ}C$ in the urban areas at whose center there were mountains. It was found that heat island potential according to the level of land cover had various values depending on the conditions of land cover. Among the areas of urbanization, the industrial area's heat island potential is 6 to $8^{\circ}C$, and the residential and commercial area's is $0{\sim}5^{\circ}C$, so it has been found that there is high possibility to induce urban heat islands. Meanwhile, in the forest or agricultural area or the waterside, the heat island potential is $-6{\sim}-3^{\circ}C$. With this study result, it is possible to evaluate the effects of temperature increase according to the urban land use, and it can be used as foundational data to improve urban thermal environment and plan eco-friendly urban development.

Modeling of Sensorineural Hearing Loss for the Evaluation of Digital Hearing Aid Algorithms (디지털 보청기 알고리즘 평가를 위한 감음신경성 난청의 모델링)

  • 김동욱;박영철
    • Journal of Biomedical Engineering Research
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    • v.19 no.1
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    • pp.59-68
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    • 1998
  • Digital hearing aids offer many advantages over conventional analog hearing aids. With the advent of high speed digital signal processing chips, new digital techniques have been introduced to digital hearing aids. In addition, the evaluation of new ideas in hearing aids is necessarily accompanied by intensive subject-based clinical tests which requires much time and cost. In this paper, we present an objective method to evaluate and predict the performance of hearing aid systems without the help of such subject-based tests. In the hearing impairment simulation(HIS) algorithm, a sensorineural hearing impairment medel is established from auditory test data of the impaired subject being simulated. Also, the nonlinear behavior of the loudness recruitment is defined using hearing loss functions generated from the measurements. To transform the natural input sound into the impaired one, a frequency sampling filter is designed. The filter is continuously refreshed with the level-dependent frequency response function provided by the impairment model. To assess the performance, the HIS algorithm was implemented in real-time using a floating-point DSP. Signals processed with the real-time system were presented to normal subjects and their auditory data modified by the system was measured. The sensorineural hearing impairment was simulated and tested. The threshold of hearing and the speech discrimination tests exhibited the efficiency of the system in its use for the hearing impairment simulation. Using the HIS system we evaluated three typical hearing aid algorithms.

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Antihyperglycemia Effect of Medicinal Plants Mixture in Streptozotocin-Induced Diabetic Rats (Streptozotocin 유발 당뇨쥐에서 항당뇨 생약 복합물의 혈당강하 효과)

  • Park, Keum-Ju;Jin, Hwi-Seung;Park, Seung-Hee;Kim, Eun-Ho;Kim, Jae-Ki
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.12
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    • pp.1554-1559
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    • 2008
  • This study was performed to investigate the hypoglycemic effect of single and repeated oral administration of medicinal herbal mixture (AD) in streptozotocin (STZ) induced diabetic rats. Angelica decursiva, Lycium chinense and Adenophora triphylla var. japonica Hara were selected by oral glucose tolerance test (OGTT) and mixed for AD mixture. In an oral glucose tolerance test, the AD inhibited the increase in blood glucose levels at 1 hr and 2 hr and decreased incremental glycemic response area under the curve. In a single administration of AD1 (100 mg/kg) and AD2 (500 mg/kg), significant reductions by 5.3% and 12.3% were observed in fasting blood glucose level for 4 hours. During the 1 month of the experimental period, AD1 and AD2 was given to the STZ induced diabetic rats. At 4th week, the fasting blood glucose levels of AD1 and AD2 caused a fall of 25.5% and 37.9%, respectively. In addition, the body weights were decreased by 7.7% (AD1) and 1.7% (AD2), respectively, compared with diabetic control (DC, decreasing of 10.2%). This study suggests that AD could be potentially useful for fasting and post-prandial hyperglycemia treatment and all these effects concluded to the use of this plant extract to manage diabetes mellitus.

A Study on Music Summarization (음악요약 생성에 관한 연구)

  • Kim Sung-Tak;Kim Sang-Ho;Kim Hoi-Rin;Choi Ji-Hoon;Lee Han-Kyu;Hong Jin-Woo
    • Journal of Broadcast Engineering
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    • v.11 no.1 s.30
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    • pp.3-14
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    • 2006
  • Music summarization means a technique which automatically generates the most importantand representative a part or parts ill music content. The techniques of music summarization have been studied with two categories according to summary characteristics. The first one is that the repeated part is provided as music summary and the second provides the combined segments which consist of segments with different characteristics as music summary in music content In this paper, we propose and evaluate two kinds of music summarization techniques. The algorithm using multi-level vector quantization which provides a repeated part as music summary gives fixed-length music summary is evaluated by overlapping ration between hand-made repeated parts and automatically generated summary. As results, the overlapping ratios of conventional methods are 42.2% and 47.4%, but that of proposed method with fixed-length summary is 67.1%. Optimal length music summary is evaluated by the portion of overlapping between summary and repeated part which is different length according to music content and the result shows that automatically-generated summary expresses more effective part than fixed-length summary with optimal length. The cluster-based algorithm using 2-D similarity matrix and k-means algorithm provides the combined segments as music summary. In order to evaluate this algorithm, we use MOS test consisting of two questions(How many similar segments are in summarized music? How many segments are included in same structure?) and the results show good performance.

Effect of Film Layers and Storing Period on the Fermentation Quality of Whole Crop Barley Silage (청보리 사일리지의 비닐겹수 및 저장기간에 따른 발효품질)

  • Song, Tae-Hwa;Park, Tae-Il;Park, Hyong-Ho;Yoon, Chang;Kim, Yang-Kil;Park, Jong-Chul;Kang, Chon-Sik;Son, Jae-Han;Kim, Kyong-Ho;Cheong, Young-Keun;Oh, Young-Jin
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.35 no.1
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    • pp.6-11
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    • 2015
  • This study was undertaken to characterize feed value and silage quality according to storage period and film layers for whole-crop barley silage. The crude protein (CP) content increased in all silage during the storage periods compared to those before silage, this content slightly increased over the prolonged storage period but it was not significant (p>0.05). Depending on the film layers of silage, 6 layers were higher than 4 layers. The neutral detergent fiber (NDF) and acid detergent fiber (ADF) contents also increased in all silage during storage periods compared to those before silage (P<0.05), but they were maintained at similar levels during the storage period. Depending on the film layers of silage, 6 layers were higher than 4 layers. The total digestible nutrients (TDN) content decreased in all silage during the storage periods. However, it was maintained at a similar level for the duration of each storage period. Depending on the film layers of silage, 6 layers were lower than 4 layers. The pH value was decreased during the prolonged storage period and depending on the film layers, 6 layers were lower than 4 layers. In the organic acid contents during the prolonged storage period, lactic acid increased, acetic acid was lower, and butyric acid was significantly higher (p<0.05). Depending on the film layers, 6 layers showed higher levels of lactic acid and lower levels of butyric acid (p<0.05). Therefore, these results showed that 6 layer wrapping was advantageous for long term storage of whole crop barley silage, while also indicating that it is desirable to use 4 layer wrapping within a six month period.

A Criteria on Nitrate Concentration in Soil Solution and Leaf Petiole Juice for Fertigation of Cucumber (Cucumis sativus L.) under Greenhouse Cultivation (시설 오이의 관비재배를 위한 토양용액과 엽병즙액중 질산태 농도 기준 설정)

  • Lim, Jae-Hyun;Lee, In-Bog;Kim, Hong-Lim
    • Korean Journal of Soil Science and Fertilizer
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    • v.34 no.5
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    • pp.316-325
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    • 2001
  • To develope a technique for efficiently managing fertilizer for cucumber, a quick test method to quantify nitrate content in soil solution and leaf petiole juice using a simple instrument was investigated. Among the nitrate analyzing instruments such as compact ion meter, nitrate ion meter, and test strip with reflectometer, the paper test-strip used in conjunction with a hand-held reflectometer was most closely correlated with ion chromatography method in nitrate content, and then it would be suggested with a tool that a farmer can use rapidly, conveniently and accurately for nitrate analysis in a field. Nitrate content in soil solution collected by porous cup was very variable on the lapsed time after drip irrigation and the sampling positions such as soil depth and the distance from dripper. As a result, a significant correlation between nitrate contents of soil solutions and 2M KCl soil extract was not found. However, nitrate content in soil solution extracted with a volume basis (soil:water=1:2) showed the highly significant correlation with that in 2M KCl extract. Nitrate contents of cucumber leaf petiole juices was greatly different between upper and lower leaves. Eleven to sixteen positioned-leaf would be a proper sampling position to determine nitrate content in leaf petiole for evaluating nutrient state by plant tissue analysis. From the secondary regression equations between nitrate contents of soil and petiole juice and the yield of cucumber, nitrate levels for real time diagnosis were estimated as $400mg\;l^{-1}$ soil solution by porous cup. $300mg\;l^{-1}$ in a soil volume extraction, and $1400mg\;l^{-1}$ in petiole juice from spring to summer season. In addition, the maximum yield of cucumber fruit in pot test was obtained in nitrate $1500mg\;l^{-1}$ level of petiole juice, which was similar to nitrate $1400mg\;l^{-1}$ in greenhouse trial.

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Protection for sea-water intrusion by geophysical prospecting & GIS (해수침투 방지를 위한 물리검층과 GIS 활용방안)

  • Han Kyu-Eon;Yi Sang-Sun;Jeong Cha-Youn
    • 한국지구물리탐사학회:학술대회논문집
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    • 2000.09a
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    • pp.54-69
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    • 2000
  • There are groundwater trouble by high-salinity yield inducing sea-water intrusion in Cheju Island. It is used groundwater-GIS(Well-lnfo) in the maintenance and management of groundwater in Cheju Island to grasp groundwater trouble area and cause of high-salinity yield. For 16 wells certain to yield high-salinity, we logged specific electrical conductivity(EC) and tried to get hold of freshwater and saltwater relationship. As result of distribution of $Cl^-$ by depth, it is showed up groundwater trouble by high-salinity yield in the east coastal area and the partly north coastal area. The reason of high-salinity groundwater yield are low-groundwater level by the structure of geology and low-hydraulic gradient etc. There is necessity for management to development and use of groundwater in the high-salinity area, special management area.

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Resources Use Characteristics of Higher Fungi in Byeonsanbando National Park (변산반도 국립공원 고등균류의 자원이용적 특성)

  • Jang, Seog-Ki
    • Korean Journal of Environment and Ecology
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    • v.31 no.2
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    • pp.230-251
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    • 2017
  • According to the survey on higher fungi from 2009 to 2011 and also in 2015 in Byeonsanbando National Park, a total of 2 division, 6 class, 18 orders, 61 families, 157 genera and 323 species were observed. In case of Agaricales, there were 23 families, 67 genera and 153 species; Boletales, there were 6 families, 27 genera and 45 species; Russulales, there were 3 family, 4 genera and 40 species; Polyporales, there were 6 family, 21 genera, 28 species. Thus, most of them belonged to the following 4 orders: Agaricales, Russulales, Boletales and Polyporales. Dominant species belonged to Boletaceae (37 species), Russulaceae (36 species), Agaricaceae (28 species) and Amamtaceae (25 species). For the habitat environment, the ectomycorrhizal mushrooms were 40.2% (poisonous mushrooms, 46 species; edible & medicinal mushrooms, 51 species; unknown edible & poisonous mushrooms, 26 species), litter decomposing and wood rotting fungi 35.3%(poisonous mushrooms, 10 species; edible & medicinal mushrooms, 52 species; unknown edible & poisonous mushrooms, 46species), grounding Fungi 22.3%(poisonous mushrooms, 8 species; edible & medicinal mushrooms, 31 species; unknown edible & poisonous mushrooms, 29 species). Monthly, most of poisonous mushrooms, edible & medicinal mushrooms and unknown edible & poisonous mushrooms were found in July and August. In terms of altitude, the most species were observed at 1~99m and the populations dropped by a significant level at an altitude of 200m or higher. It seemed that the most diversified poisonous mushrooms, edible & medicinal mushrooms and unknown edible & poisonous mushrooms occurred at climate conditions with a mean air temperature at $24.0{\sim}25.9^{\circ}C$, the highest air temperature at $28.0{\sim}29.9^{\circ}C$, the lowest air temperature at $20.0{\sim}21.9^{\circ}C$, a relative humidity at 77.0~79.9% and a rainfall of 300.0~499.9mm.

Effects of Aqueous Chlorine Dioxide against Escherichia coli O157:H7 and Listeria monocytogenes on Broccoli Served in Foodservice Institutions (급식소에서 제공되는 브로콜리에 있어 이산화염소 처리가 Escherichia coli O157:H7과 Listeria monocytogenes의 균수에 미치는 영향)

  • Ryu, Si-Hyun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.12
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    • pp.1622-1627
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    • 2007
  • This study was undertaken to evaluate the effects of chlorine dioxide on reducing E. coli O157:H7 and L. monocytogenes on broccoli served in foodservice institutions. Broccoli samples inoculated with $10^6$ CFU/mL of E. coli O157:H7 and L. monocytogenes were treated with chlorine dioxide. Treatments with 5, 10, and 20 ppm for 1, 5, and 10 min were not sufficient in controlling E. coli O157:H7 on broccoli. L. monocytogenes were effectively reduced by $2.19{\sim}2.48log\;CFU/g\;and\;3.31{\sim}3.87log\;CFU/g$ with 10 and 20 ppm chlorine dioxide for 1, 5, and 10 min treatment, respectively, compared with the control. E. coli O157:H7 and L. monocytogenes population were significantly negatively correlated with concentration and treatment time of chlorine dioxide. These results show that the use of chlorine dioxide was effective in sanitizing L. monocytogenes on broccoli and the level of concentration was more associated with populations of E. coli O157:H7 and L. monocytogenes than treatment time of chlorine dioxide on broccoli.