• 한국기술혁신학회:학술대회논문집
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• 한국기술혁신학회 2015년도 추계학술대회 논문집
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• pp.867-883
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• 2015

• The Korean Journal of Physiology and Pharmacology
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• 제9권1호
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• pp.29-35
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• 2005

To prove the buffering contribution of mitochondria to the increase of intracellular $Ca^{2+}$ level ($[Ca^{2+}]_i$) via background nonselective cation channel (background NSCC), we examined whether inhibition of mitochondria by protonophore carbonylcyanide m-chlorophenylhydrazone (CCCP) affects endothelial $Ca^{2+}$ entry and $Ca^{2+}$ buffering in freshly isolated rabbit aortic endothelial cells (RAECs). The ratio of fluorescence by fura-2 AM ($R_{340/380}$) was measured in RAECs. Biological state was checked by application of acetylcholine (ACh) and ACh ($10{\mu}M$) increased $R_{340/380}$ by $1.1{\pm}0.15$ ($mean{\pm}S.E.$, n=6). When the external $Na^+$ was totally replaced by $NMDG^+$, $R_{340/380}$ was increased by $1.19{\pm}0.17$ in a reversible manner (n=27). $NMDG^+$-induced $[Ca^{2+}]_i$ increase was followed by oscillatory decay after $[Ca^{2+}]_i$ reached the peak level. The increase of $[Ca^{2+}]_i$ by $NMDG^+$ was completely suppressed by replacement with $Cs^+$. When $1{\mu}M$ CCCP was applied to bath solution, the ratio of $[Ca^{2+}]_i$ was increased by $0.4{\pm}0.06$ (n=31). When $1{\mu}M$ CCCP was used for pretreatment before application of $NMDG^+$, oscillatory decay of $[Ca^{2+}]_i$ by $NMDG^+$ was significantly inhibited compared to the control (p＜0.05). In addition, $NMDG^+-induced$ increase of $[Ca^{2+}]_i$ was highly enhanced by pretreatment with $2{\mu}M$ CCCP by $320{\pm}93.7$%, compared to the control ($mean{\pm}S.E.$, n=12). From these results, it is concluded that mitochondria might have buffering contribution to the $[Ca^{2+}]_i$ increase through regulation of the background NSCC in RAECs.

• Asian-Australasian Journal of Animal Sciences
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• 제25권3호
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• pp.299-303
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• 2012

Inbreeding is the mating of relatives that produce progeny having more homozygous alleles than non-inbred animals. Inbreeding increases numbers of recessive alleles, which is often associated with decreased performance known as inbreeding depression. The magnitude of inbreeding depression depends on the level of inbreeding in the animal. Level of inbreeding is expressed by the inbreeding coefficient. One breeding goal in livestock is uniform productivity while maintaining acceptable inbreeding levels, especially keeping inbreeding less than 20%. However, in closed herds without the introduction of new genetic sources high levels of inbreeding over time are unavoidable. One method that increases selection response and minimizes inbreeding is selection of individuals by weighting estimated breeding values with average relationships among individuals. Optimum genetic contribution theory (OGC) uses relationships among individuals as weighting factors. The algorithm is as follows: i) Identify the individual having the best EBV; ii) Calculate average relationships ($\bar{r_j}$) between selected and candidates; iii) Select the individual having the best EBV adjusted for average relationships using the weighting factor k, $EBV^*=EBV_j(1-k\bar{{r}_j})$ Repeat process until the number of individuals selected equals number required. The objective of this study was to compare simulated results based on OGC selection under different conditions over 30 generations. Individuals (n = 110) were generated for the base population with pseudo random numbers of N~ (0, 3), ten were assumed male, and the remainder female. Each male was mated to ten females, and every female was assumed to have 5 progeny resulting in 500 individuals in the following generation. Results showed the OGC algorithm effectively controlled inbreeding and maintained consistent increases in selection response. Difference in breeding values between selection with OGC algorithm and by EBV only was 8%, however, rate of inbreeding was controlled by 47% after 20 generation. These results indicate that the OGC algorithm can be used effectively in long-term selection programs.

• 한국BIM학회 논문집
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• 제9권3호
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• pp.41-53
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• 2019

As a central part in smart construction, BIM has been rapidly spread in construction industry at large. However, the level of applying BIM in construction stage is still relatively lower than that in design stage due to unclear application method, inadequate design BIM model, technical faults of BIM itself, etc. Under these circumstances, public owners inevitably need to adjust the scope and pace in BIM application considering their internal support and capabilities of contractors. This study aims to suggest major BIM-applicable tasks during construction stage in the process of establishing gradual long-term and short-term introduction strategy for public apartment housing projects. Those major tasks were identified with the combination of the importance of tasks and the future benefits of BIM using IPA method. To do so, the degrees of contribution to achieving objectives in construction, current task execution, and communication requirement were investigated by internal site managers. On the other hand, the expected benefits and current level of using BIM were assessed by BIM experts. Among operational tasks by phases, design review, construction plan review, making as-built drawing, etc. were categorized as major tasks. In addition, progress control, regular meeting, master schedule development, work inspection, on-site quality check, etc. were also drawn as major tasks by management areas. The results of this study will provide the useful reference for owners concerned about the introduction of new technologies.

• 유통과학연구
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• 제15권2호
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• pp.69-78
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• 2017

Purpose - As recently social contributions of firms are positioned as key strategic actions, it is demanding to review the effects of social contributions on overall corporate management. The research aims to effects of social contributions on social values and word of mouth in firm level and product level. Further roles of consumer identification with firm and product eco-friendliness are also analyzed. Research design, data, and methodology - The paper conducted a survey in which two scenarios are used for manipulating the degree of corporate social contributions. The survey sample consist of 165 undergraduate and graduate students in a university, located in Seoul. For analyzing data, analysis of variance is applied, in conjunction with analysis of moderating effects, through version 23 of SPSS statistical package. Results - In the firm level, social contributions by firms have a positive effect on social values of firms. Consumer identification showed a moderating role in the effect. Social value of the firm with passive social contribution perceived by respondents with a high degree of identification was higher than social value of the firm with active social contribution perceived by respondents with a low degree of identification. Corporate social value has positive effect on word-of-mouth of firms. In the product level, social contributions by firms has a positive effect on social values of product. Product eco-friendliness showed a moderating role in the effect. For eco-friendly product, social values are higher in the firm with active social contributions than in the firm with passive social contributions. However, for non eco-friendly product, the difference in social values between the two firms does not exist. Product social values has positive effect on intention for WOM of products. WOM of eco-friendly products with low social value showed no difference with WOM of non eco-friendly products with high social value. Conclusions - These results imply that firms should enhance consumer identification with firm in making social contributions for optimizing corporate social value and enhancing word-of-mouth(WOM). Managerial implications of the results suggest it would be more effective to improve social value of product by active social contributions for increasing word-of-mouth(WOM) of product.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2012년도 춘계학술대회 논문집
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• pp.204-205
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• 2012

• 한국정보시스템학회지:정보시스템연구
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• 제22권4호
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• pp.71-84
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• 2013

The main purpose of this study is to identify the factors influencing the implementation performance of ERP system from the investment such as hardware, software and consulting fee. The main goal of this study to analyze of ERP system implementation in various sections depending on the amount of investment and research about the contribution of ERP utilization on overall PCB business activities. Survey questionnaires were distributed via post and fax to PCB (Printed Circuit Board)Company in Korea. The results of this study can be summarized as follow. First, only 43.1% of respondents implemented ERP system at the enterprise level, which shows that ERP system does not completely play its role as a truly integrated system. Second, companies shows higher satisfaction rate with selectively invested on particular sub-modules. Third, the efficiency of ERP system can be maximized by improving efficiency on core areas through selective investments. Also, this can be maximized by performing overall investments on the general environment in addition to the direct investment on ERP. Lastly, 59.26% of respondents reported that the utilization of ERP has highly significant effects on the contribution of business whereas 29.63% respondents reported as significant effects on the business. These shows positive effects of ERP on the contribution of business.

• 한국환경과학회지
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• 제3권4호
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• pp.393-402
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• 1994

It is necessary to examine the source contributions and the relationship between a receptor and sources for the resonable controlling of air pollution level of suspended particulate matters. Therefore, in this study, profiles of sources contributing to the concentration of suspended particulate matters, were developed and CMB model was applied to obtain information of source contributions and feasibility of CMB model application. According to the propose of this study, twenty-seven chemical species such as the elements, anions, and total carbon of thirty-six PMl0 and TSP data sets sampled at the Pomch'on receptor site in Pusan for a 24-hr period from May to Aug. 1992, were analyzed and three (transportation, soil, marine) different source profiles were developed through the field measurement. Applying CMB model to transportation, soil, marine, the results of source contribution by CMB model showed that the case with TSP was more suitable for CMB model than that with PMl0. And the average contribution of transportation source to TSP and PMlo concentration at Pomch'on receptor was calculated as 90.66 ㎍/m3(64%) and 23.27 ㎍/m3(39%), resfiectively, which showed that the contribution by transportation was dominant. The validation of CMB model was performed by means of the results of contributions from marine source for the wind direction sectors.

• 보건의료산업학회지
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• 제5권4호
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• pp.95-111
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• 2011

The purpose of this study was to explore and analyse the work value of university students majoring in health care management. The subjects of this study were 300 students. Maryland Work Value Inventory was used and the data were collected using a structured and self-administrated questionnaire. As a result of factor analysis, the following results were obtained. First, the work value consists of six factors (financial remuneration, social status, social contribution, capability, achievement, proper pride) and it can be classified extrinsic work value (financial remuneration, social status) and intrinsic work value(social contribution, capability, achievement, proper pride). Second, The mean extrinsic work value(4.16) was higher than the mean intrinsic work value(3.80). The preference order of the work value was like this; financial remuneration(4.36) the first, achievement(4.05), social status(3.96), proper pride(3.93), capability(3.78), and social contribution(3.45) the last. Third, the mean of the economic stability in extrinsic work value was the highest. The factors meaningfully relating with intrinsic work value were age, school grade and the experience of job. Forth, as a result of regression analysis, the more school grade they have, the less extrinsic work value and the less their mother's level of education, the higher extrinsic work value.

• 한국환경보건학회지
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• 제29권4호
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• pp.10-16
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• 2003

Atmospheric samples were conducted from September 2001 to July 2002 with GPS-l PUF sampler in rural site to concentration distributions of gas/particle PCBs and to calculate dry deposition flux of PCBs. $\Sigma$PCBs concentrations of gas/particle PCBs were 59.29$\pm$48.83, 6.56$\pm$6.59 pg/㎥, respectively. Gas contribution (%) of total PCBs (gas + particle) was 90% which existed gas phase in the atmosphere. The particle contribution (%) of PCB congeners increased relatively more of the less volatile congeners with the highest chlorine number. The correlation coefficients (r) between total PCBs and temperature ($^{\circ}C$) showed negative correlation in - 0.62 (p<0.0l) for particle phase, positive correlation in 0.63 (p<0.01) for gas phase. In other word, particle phase PCBs is enriched in colder weather which could be due to greater in corporation of condensed gas phase at low temperature. The calculated dry deposition of total PCBs (gas + particle) was 0.008, 0.008 $\mu\textrm{g}$ $m^{-2}$ da $y^{-l}$ which showed maximum dry deposition flux in December, minimum data in July Bs in the atmosphere. The calculated dry deposition fluxes of total PCBs were influenced by particle phase PCBs even though PCBs in the atmosphere were present primarily in the gas phase.e.