• Journal of the Korean Applied Science and Technology
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• v.24 no.3
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• pp.253-263
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• 2007

Three different weather-resistant coatings were fabricated with the various weight ratios of a mill-base silicone/acrylic resin to let-down silicone /acrylic resin at 2:8, 3:7, and 4:6 respectively. The prepared coatings were tested to investigate the effect of composition of weather-resistant coatings on the physical properties. The thermal stability, salt spray exposure, and weather-resistance were improved with the increased silicone content. It was concluded that the optimum retio of mill-base silicone/acrylic resin to let-down silicone/acrylic resin would be 2:8 and the coating with 30 wt% of silicone content would have high weather-resistance.

• Molecules and Cells
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• v.39 no.4
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• pp.345-351
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• 2016

Wound healing is a complex physiological process necessitating the coordinated action of various cell types, signals and microRNAs (miRNAs). However, little is known regarding the role of miRNAs in mediating this process. In the present study, we show that let-7c miRNA is decreased in heat-denatured fibroblasts and that inhibiting let-7c expression leads to the increased proliferation and migration of dermal fibroblasts, whereas the overexpression of let-7c exerts an opposite effect. Further investigation has identified heat shock protein 70 as a direct target of let-7c and has demonstrated that the expression of HSP70 in fibroblasts is negatively correlated with let-7c levels. Moreover, down-regulation of let-7c expression is accompanied by up-regulation of Bcl-2 expression and down-regulation of Bax expression, both of which are the downstream genes of HSP70. Notably, the knockdown of HSP70 by HSP70 siRNA apparently abrogates the stimulatory effect of let-7c inhibitor on heat-denatured fibroblasts proliferation and migration. Overall, we have identified let-7c as a key regulator that inhibits fibroblasts proliferation and migration during wound healing.

• Kyungpook Mathematical Journal
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• v.51 no.1
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• pp.1-10
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• 2011

Let (R, T) be a normal pair of commutative rings (i.e., R ${\subseteq}$ T is a unita extension of commutative rings, not necessarily integral domains, such that S is integrally closed in T for each ring S such that R ${\subseteq}$ S ${\subseteq}$ T) such that the total quotient ring of R is a von Neumann regular ring. Let P be one of the following ring-theoretic properties: going-down ring, extensionally going-down (EGD) ring, locally divided ring. Then R has P if and only if T has P. An example shows that the "if" part of the assertion fails if P is taken to be the "divided domain" property.

• Polymer(Korea)
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• v.30 no.4
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• pp.350-356
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• 2006

In order to investigate the effect of the composition of weather-resistant coatings on physical properties, three different weather-resistant coatings were prepared by varying the ratio of a mill-base silicone/acrylic resin and let-down silicone/acrylic resin in weight ratios of 2 : 8, 3 : 7, and 4 : 6. The physical properties and weather-resistance of the prepared coatings were tested. It was found that the thermal stability, salt spray exposure, and weather-resistance were improved with increasing the amount of silicone. The optimum mixing ratio of mill-base silicone/acrylic resin to the let-down silicone/acrylic resin was 2 : 8. The coating containing silicone component of 30 wt% was found to be suitable as high weather-resistant coatings.

• Journal of Radiation Protection and Research
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• v.10 no.2
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• pp.89-95
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• 1985

An alternative estimator for dose equivalent was derived. The original LET distribution concept was transformed into a charged particle fluence spectrum concept along with the definition of an average quality factor named slowing-down averaged quality factor by adopting the continuous slowing down approximation. With the alternative estimator, the dose equivalent delivered into a receptor located in a given radiation field can be directly and conveniently estimated in a Monte Carlo procedure. The slowing-down averaged quality factors for the energy range below 10 MeV were evaluated and tabulated for the charged particles which may be generated from the interactions of neutron with the nuclei composing soft tissue.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.1887-1890
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• 2016

Breast cancer is the most common cause of cancer-related death among women in the whole world. MiR- 34a and let-7a are well known tumor suppressors that participate in the regulation of apoptosis, invasion and other cellular functions. In this study, expression of miR-34a, let-7a and apoptosis pathway genes such as Bcl-2, Caspase-3 and P53 were evaluated using quantitative real-time PCR in 45 paired samples of normal margin and tumor tissue collected from breast cancer patient at advanced stage (3-4). MiR-34a, let-7a, caspase-3 and P53 expression are reduced and Bcl-2 expression is increased within tumoral tissues in comparison with normal margin tissues. P53 expression directly or indirectly was correlated with miR-34a, let-7a, Bcl-2 and caspase-3 expression. In This study we found that MiR-34a and let-7a expression are reduced in the tumoral tissues. Down-regulation of these two molecules correlated with expression of genes associated with apoptosis. These results suggest that due to the correlation of miR-34a and let-7a with apoptotic and anti-apoptotic pathways these molecules could participate as regulators in advanced clinical stages of breast cancer and should be considered as markers for diagnosis, prognostic assessment and targeted therapy.

• Journal of Korean Society for Quality Management
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• v.32 no.4
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• pp.196-207
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• 2004

TDR(Tear Down & Redesign)means that renounce the past resolutely, from a white paper condition, let's change directions. That is, let's redesign from the basic of the establishment of the construction process. Through the switchover the conception, innovate totally the whole existing processes. TDR is the best core innovation activity. The ultimate aim of the TDR activity induces the employees to do more productive business and obtain excellent results in the future by solving the problems, which are the nonproductive business in the business process on the objective view, the business that customers don't recognize the value, the same old practice of business, and the unsettled business from the restriction of resources. By organizing the related to workers of those business, they can solve the problems for 3-4months by full time working This paper inquires what are the obstruction factors on the process of executing TDR activity. Through the search of the reformation plan for the improvement of immersion degree, it presents some methods to be successful business.

• Journal of the Korean Society of Marine Environment & Safety
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• v.6 no.1
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• pp.35-45
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• 2000

The slipway, which is one of stern construction, is necessary for stern trawler to let fishing implements, such as fishing net, otter board and warp, go out effectively. It may be doubtable whether there is any possibility for deckwetness to occur because the slipway is obliquely in contact with sea surface. The author discusses any possibility for deckwetness through slipway of stern trawler in wind and waves. A 350 G/T class, ocean-going stern trawler is adopted for the present study. The stem trawler is particularly assumed to drift with fishing implements hung down the slipway due to internal or external accident during fishing operation in real sea. The author considers two factors as possibility for deckwetness to occur through slipway. One is mooring effect of fishing implements hung down the slipway under wind pressure, and the other is relative ship motion in vertical direction in waves. Through the numerical calculation, the author clarifies that there is thin possibility for deckwetness to occur from above two points of view.

• Journal of Korean Society of Disaster and Security
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• v.14 no.2
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• pp.25-33
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• 2021

This technology is to let rainwater flow into a waterway that is located side gutter of a street with blocking garbage including cigarette butts at the same time. The first waterway is located beside the sidewalk and it enhances the water circulation in a city. This waterway is filled with aggregates and filter media, which removes fine dust that is washed out of the street and let water flow down to the earth. The second waterway is located beside the street and it retains rainwater temporarily with decreasing its flow speed. The second waterway shall reduce flooding damages by avoiding bottleneck situation in the street inlets and storm water pipelines which is the main causation of flooding in a city.

• Journal of the Daesoon Academy of Sciences
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• v.16
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• pp.1-23
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• 2003

The Jeungsan(1871-1909)'s revelation is the important meaning. Jeungsan hands down the two revelation for solution of Chosun postscript problem and presentation of Utopia. One time Suwun(1824~1864) is handed down and afterwords Jeongsan(1895-1958) after Jeungsan's Hwachon at 1917. Two revelations accomplish the day of the Jeungsan in public but the character is the countenance. The Jeungsan's revelation to Suwun solves present generation problems, the Jeungsan revelation to Jeongsan is continuously to do the day of the Jeungsan even after Hwachon. The Jeungsan stepped on the failure of the Donghak and on the upper lifestyle with the Cham-Donghag it opened the different side. The Cham-Donghag is concerned about the future Chosun to be the first-class country and Chosun Haewon is related with Danju Haewon. Danju Haewon is to be a fifty years religous study of Jeongsan. The Jeungsan's Gangse is to accomplish the Sungsajaein and it actualizes the appearance of Dotonggunja. Jeongsan is trying to do the religious activity about Sungsajaein and Dotonggunja as the Daedumok. The Jeungsan starts from revelation to the Suwun, to accomplish thought of the Cham-Donghag after Hwachon. The Jeungsan continuously has handed revelation led from religion activity, let Jeongsan do fifty years religious study. In the long run, it completes the fact that it accomplishes the outer space and the Chosun society of new setup, and a sacred religious work has been arranged the advocate of the Cham-Donghag through the Jeongsan by Woodang(1917-1996)'s Daesoonjinrihoe(1969).