• Archives of Plastic Surgery
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• 제49권4호
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• pp.527-530
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• 2022

Lupus panniculitis (LP) often presents with tender nodules and intermittent ulcers that then heal with scarring and lipoatrophy. The current mainstay of treatment is medical treatment. Research regarding the treatment of lipoatrophy from LP with autologous fat grafting is limited. We would like to share our experience in this rare case, which was treated with autologous fat transfer. A 48-year-old female presented with erythematous plaque, tender nodules, and ulcers following by a depression of the lesion at the left temporal area. The patient also had indurated erythematous plaque at her left cheek. Both lesions were aggravated by sunlight exposure. After several investigations, she was diagnosed as LP with secondary lipoatrophy and tumid lupus erythematosus at her left temporal and left cheek, respectively. She received antimalarial drug and topical steroids. The patient underwent two sessions of autologous fat transfer. She was satisfied with the volume and contour improvement in the scar following the injection of 8 and 3.7 mL of fat. Furthermore, the patient reported the remission of tender nodules and ulcers since the first fat graft injection. In conclusion, the autologous fat transfer is a simple and effective treatment for lipoatrophy and scar secondary to LP with promising results.

• Journal of Korean Neurosurgical Society
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• 제30권3호
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• pp.366-370
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• 2001

Objective : The authors present three cases of brain tumors in which epidural hematomas(EDHs) were developed postoperatively in the remote areas from craniotomy sites. The preventive tactics as well as possible mechanisms of development of remote EDH are discussed. Material and Methods : The magnetic resonance imagings of three patients revealed a left lateral ventricular mass located just aside of foramen Monro in a 27-year-old male, a large cystic mass in the temporal lobe in a 35-year-old male, and a partially calcified pineal mass in a 27-year-old male patient. The surgical removals of these tumors were performed without any noticeable events during surgery via left frontal transcortical transventricular approach for lateral ventricular tumor, left temporal craniotomy for cystic temporal tumor, and right occipital transtentorial approach for pineal tumor. Results : Postoperative EDHs remote from the sites of craniotomy were detected by the immediate postoperative computerized tomographic scans. We obtained good outcomes without any morbidity in all three patients with emergent evacuation of the hematoma. The pathologic diagnoses were lateral ventricular ependymoastrocytoma, temporal craniopharyngioma and mixed germinoma of the pineal region. Conclusion : It is postulated that a sudden reduction of intracranial pressure(ICP) at the time of tumor removal may strip the dura from the inner table of the skull to cause EDH from the remote site of craniotomy. Gradual reduction of ICP with slow drainage of cerebrospinal fluid before tumor removal as well as lowering the head position of patient during surgery might be helpful for preventing this unusual complication.

• 인지과학
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• 제21권1호
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• pp.77-93
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• 2010

본 연구는 마음이론 능력 측정 과제의 하나인 헛디딤 탐지를 수행하는데 관여하는 신경상관 영역을 확인하려는 것이었다. 기능적 자기공명영상 기법을 이용하여 헛디딤 이야기 문장과 헛디딤을 포함하지 않는 통제 이야기 문장을 제시하였을 때 나타나는 뇌 활성화 영역을 비교하였다. 양 반구의 상전두회(BA 6/9)와 설전소엽(BA 7), 좌반구의 내전두회(BA 9), 상측두회(BA 38), 하측두회(BA 20)와 우반구의 하두정소엽(BA 40), 중심후회(BA 1), 설회(BA 18), 횡전두회(BA 41) 등의 영역에서 활성화가 나타났다. 헛디딤 탐지를 하는 동안 안와전두피질과 편도의 활성화는 나타나지 않았다. 이런 결과는 마음이론과 관련된 뇌 활성화는 과제가 이끌어내는 마음상태의 유형에 달려있음을 시사한다.

• 생물정신의학
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• 제16권3호
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• pp.159-169
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• 2009

Objectives : This study aimed to investigate the difference of brain activities in viewing a common emotional situation according to perspective-taking. Methods : Using fMRI, brain activities were measured while performing the task viewing a common emotional situation on either self-perspective or third-person perspective in fourteen healthy men. The relatively activated brain areas on each perspective were investigated, then the relationship between the activated brain regions and the scores of self report about some emotion or empathic ability were explored. Results : The relatively activated brain areas on self-perspective were bilateral paracentral lobule(BA 5), right postcentral gyrus(BA 3), right precentral gyrus(BA 4), left superior temporal gyrus(BA 22), left medial frontal gyrus(BA 6), whereas on third-person perspective right inferior frontal gyrus(BA 47), left caudate body and tail, right superior temporal gyrus(BA 38), right medial frontal gyrus(BA 8) were activated. The relative activity of left superior temporal gyrus on self-perspective was positively correlated with the score of Beck Depression Inventory. Conclusion : This study demonstrated that the activated brain region according to perspective-taking were different while viewing a common emotional situation. The depressive feeling would have an influence on the brain activity related to perspective-taking.

• 정신신체의학
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• 제4권1호
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• pp.64-70
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• 1996

The prevalence rate of psychiatric symptoms of the refractory epileptic patients was evaluated according to the location of the epileptic focus. The subjects were 91 patients admitted to Epilepsy Monitoring Unit of Seoul National University Hospital. The psychiatric symptoms were assessed by Korean version of Symptom Checklist-90-R(SCL-90-R). The locus of epileptic focus was assessed by clinical features, 2-hour interictal EEG, long-term video-EEG monitoring, brain MRI, interictal and ictal brain SPECT, and interictal brain PET The subjects were divided into three groups according to the epileptic focus, non-temporal(N=29), left temporal (N=26), and right temporal(N=32). There were no statistical differences in demographic and seizure-related variables among groups. The number of patients with $T-score {\geq} 65$ at any subscale of the SCL-90-R were compared by $X^2-test$ among groups. The mean T-scores of each subscale of the SCL-90-R were compared by oneway-ANOVA among groups. The prevalence rate of psychiatric symptoms of the refractory epileptic patients was 38.5%. There was no statistical difference in the prevalence rate of psychiatric symptoms among groups. However, the patients with non-temporal or right temporal epileptic foci showed statistically significant higher mean T-scores of interpersonal sensitivity, depression, hostility, and phobic subscales than the patients with left temporal epileptic foci. These results suggest that the epileptic focus plays an important role in the production of interictal psychiatric symptoms of the refractory epileptics.

• 한국초등과학교육학회지:초등과학교육
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• 제32권4호
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• pp.567-580
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• 2013

This study is to activate gifted students' brains for creativity ability and also an integrated science and art teaching program. The learning programs integrating science and art, which have 30 periods and 10 topics on art and the knowledge of science, were developed dependant on five steps - observing, having interests and curiosity, experimental designing and performing, internalizing, and expressing in an arts-based manner. This programs were applied to 20 senior gifted students in Y Elementary School in Gyeonggi province, by one group pretest-posttest design. The results from these integrated programs of science and art are as follows: First, in the performance of science tasks, prefrontal lobe(F7, FT7) of left brain increase the relative power of theta wave, whereas in the performance of drawing tasks increase the relative power of beta wave in prefrontal lobe(FP1) of left brain, bilateral frontal(F7, F3, Fz, F4, F8, FT7, FC3, FCz), bilateral temporal(T7, TP7, TP8, P7), parietal lobe of left brain(CP3, CPz, P3, Pz), bilateral occipital(O1, Oz, O2). Second, in the performance of science tasks, the relative power of beta wave activity in the left temporal lobe(T7) of the brains of talented students in science significantly decreased whereas it was greatly activated in another part, the left frontal lobe(F3) of the brain (p<.05). Third, in the performance of drawing tasks, the relative power of theta wave activity in five areas of the brain, namely the left temporal lobe(T7), the left frontal lobe(F3), the right frontal lobe(F4), and the left and right parietal lobes of gifted students in science who took the course of the integrated programs, was considerably increased statistically(p<.05). On top of that, these programs were especially effective in balancing the symmetrical development of both cerebral hemispheres by multiplying theta wave activity in the frontal lobes(F3, F4) and the parietal lobes(CP3, P3, P4), which are particularly related to creative thinking. According to the results of this study of brain-based teaching strategies combining science and art, it is an effective program to develop overall activate gifted students' brains for creativity ability. This is expected to be utilized to activate the brain areas for creativity of gifted students in science.

• Communications for Statistical Applications and Methods
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• 제30권6호
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• pp.561-575
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• 2023

Brain network analysis has attracted the interest of neuroscience researchers in studying brain diseases. Magnetoencephalography (MEG) is especially proper for analyzing functional connectivity due to high temporal and spatial resolution. The application of graph theory for functional connectivity analysis has been studied widely, but research on network modeling for MEG still needs more. Temporal exponential random graph model (TERGM) considers temporal dependencies of networks. We performed the brain network analysis, including static/temporal network statistics, on two groups of epilepsy patients who removed the left (LT) or right (RT) part of the brain and healthy controls. We investigate network differences using Multiset canonical correlation analysis (MCCA) and TERGM between epilepsy patients and healthy controls (HC). The brain network of healthy controls had fewer temporal changes than patient groups. As a result of TERGM, on the simulation networks, LT and RT had less stable state than HC in the network connectivity structure. HC had a stable state of the brain network.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2000년도 춘계 학술대회 및 국제 감성공학 심포지움 논문집 Proceeding of the 2000 Spring Conference of KOSES and International Sensibility Ergonomics Symposium
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• pp.113-119
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• 2000

The Pansori is a Korean traditional vocal music that has a unique story and melody which converts deep emotion into art. It has both verbal and emotional components. which can be coordinated by large-scale neural network. The purpose of this study is to illustrate the cortical network activated by a Korean traditional opera, Pansori, with different emotional valence using functional MRI (fMRI).Nine right-handed volunteers participated. Their mean age was 25.3 and the mean modified Edinburgh score was +90.1. Activation tasks were designed for the subjects to passively listen to the two parts of Pansories with sad or hilarious emotional valence. White noise was introduced during the control periods. Imaging was conducted on a 1.5T Siemens Vision Vision scanner. Single-shot echoplanar fMRI scans (TR/TE 3840/40 ms, flip angle 90, FOV 220, 64 x 64 matrix, 6mm thickness) were acquired in 20 contiguous slices. Imaging data were motion-corrected, coregistered, normalized, and smoothed using SPM-96 software.Bilateral posterior temporal regions were activated in both of Pansori tasks, but different asymmetry between the tasks was found. The Pansori with sad emotion showed more activation in the light superior temporal regions as well as the right inferior frontal and the orbitofrontal areas than in the right superior temporal regions as well as the right inferior frontal and the orbitofrontal areas than in the left side. In the Pansori with hilarious emotion, there was a remarkable activation in the left hemisphere especially at the posterior temporal and the temporooccipital regions as well as in the left inferior and the prefrontal areas. After subtraction between two tasks, the sad Pansori showed more activation in the right temporoparietal and the orbitofrontal areas, in contrast, the one with hilarious emotion showed more activation in the left temporal and the prefrontal areas. These results suggested that different hemispheric asymmetry and cortical areas are subserved for the processing of different emotional valences carried by the Pansories.

• Journal of Korean Neurosurgical Society
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• 제46권5호
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• pp.488-491
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• 2009

A 31-year-old man presented with right hemiparesis, and magnetic resonance imaging revealed a small infarct at left basal ganglia. Digital subtraction angiography showed left cervical internal carotid artery (ICA) occlusion and severe stenosis of the ipsilateral external carotid artery (ECA) with collateral cerebral circulation fed by ECAs. Based on the results of a functional evaluation of cerebral blood flow, we performed preventive ECA angioplasty and stenting for advanced ECA stenosis to ensure sufficient blood flow to the superficial temporal artery. Eight weeks later, superficial temporal artery to middle cerebral artery (STA-MCA) anastomosis was performed. His postoperative course was uneventful and no additional transient ischemic attacks have occurred. To our knowledge, this is the first report of preventive angioplasty and stenting for advanced narrowing of an ECA before STA-MCA anastomosis for ipsilateral ICA occlusion.

• 대한치과보철학회지
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• 제25권1호
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• pp.213-226
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• 1987

The purpose of this study was to standardize and classify the coordination pattern among the left and right masseter and anterior temporal muscles, in terms of integrated EMG values per stroke during gum chewing in normal subjects. In this study, 20 normal subjects were selected to chew a piece of gum and integrated EMG from middle portion of the masseter and anterior temporal muscles on both sides were recorded 20 times during each of the right and left chewing respectively. And the Bioelectric Processor Model EM2 (Myo-tronies Research, Inc., U.S.A.) with the surface electrodes was used to record the EMG activity during all experimental procedures. The results were as follows; 1. In all subjects, the chewing side masseter muscle was predominantly active among the four muscles examined. 2. The integrated EMG value of the middle of masseter muscle was significantly predominant than those of the anterior temporal muscle (p<0.0001) on the chewing side, but no significant predominant was observed on the nonchewing side (p<0.98). 3. In comparison with same muscles on the chewing and nonchewing side, low correlation coefficient was found between the middle of masseter muscles (R=0.317), but high correlation coefficient was found between the anterior temporal muscles (R=0.738). Between two muscles on the same side, there were significant correlation in the chewing (R=0.557) and nonchewing side (R=0.625). 4. In the coordination patterns among four muscles examined, distinct individual differences were found, but in an identical subject one fixed pattern appeared with significant reproducibility.