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유산소운동이 여자 아동의 뇌세포 생성 관련인자에 미치는 영향 (Effect of Aerobic Exercise on Factors Relative to the Brain Nerve Growth in Girls)

  • 편미영;조한샘;전재영;김종원;이경희;임춘규;김태운;김현준;곽이섭;고기준
    • 생명과학회지
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    • 제20권6호
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    • pp.948-954
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    • 2010
  • 운동은 신경의 생성, 적응, 보호 기능을 통해 뇌 기능 및 생성에 긍정적인 영향을 미치며, 유산소운동은 뇌신경 성장인자(GH, IGF-1, estrogen, serotonin)를 변화시키는 것으로 보고되었다. 본 연구는 여자 아동의 뇌기능 발달 및 뇌세포 생성 유도인자의 유산소운동 효과를 알아보고자 유산소운동 프로그램에 따른 뇌신경 성장인자(GH, IGF-1, estrogen, serotonin)의 변화를 분석하여 다음과 같은 결론을 얻었다. 반복측정 분산분석에 의해 운동군과 대조군의 평균을 비교한 결과 유산소운동은 집단간 유의한 차이를 보이며 체중, BMI, 체지방량, 체지방률을 감소 시켰으며, 제지방률을 증가시켰다. 또한 뇌신경 성장인자인 serotonin을 감소시켰으며, GH와 IGF-1을 증가시켰다. 본 연구결과 유산소운동 프로그램이 아동의 체중, BMI, 체지방, 체지방률 감소와 제지방률 증가에 효과적이다. 또한 serotonin이 운동 후 감소된 결과를 볼 때 유산소운동 프로그램이 아동의 중추피로 감소에 효과적이며, GH, IGF-1의 운동 후 증가된 결과를 볼 때 유산소운동이 아동의 뇌기능 발달 및 뇌세포 생성 유도에 긍정적인 프로그램임을 알 수 있다.

Genetic parameter estimation for reproductive traits in QingYu pigs and comparison of carcass and meat quality traits to Berkshire×QingYu crossbred pigs

  • Luo, Jia;Yang, Yiting;Liao, Kun;Liu, Bin;Chen, Ying;Shen, Linyuan;Chen, Lei;Jiang, An'an;Liu, Yihui;Li, Qiang;Wang, Jinyong;Li, Xuewei;Zhang, Shunhua;Zhu, Li
    • Asian-Australasian Journal of Animal Sciences
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    • 제33권8호
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    • pp.1224-1232
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    • 2020
  • Objective: The QingYu pig is well known for its excellent meat quality attributes in Sichuan province, China. In order to improve its production efficiency, the determination of genetic factors contributing to quantifiable economic traits of livestock is important. Moreover, the cross-breeding of QingYu pigs with western breeds possessing strong growth attributes is an efficient way to improve the performance of this breed. Methods: Here, the genetic parameters of several important reproductive traits of QingYu pigs were estimated, include total number born (TNB), number born alive, litter birth weight, individual birth weight, number of piglets weaned, litter weaning weight, and individual weaning weight. The data was analyzed using the ASReml 3.0 software (NSW Inc., Sydney, Australia). Furthermore, the effects of crossing Berkshire with QingYu (BQ) pigs on carcass and meat quality traits, as well as the effects of slaughter weight on carcass and meat quality of BQ were characterized. Results: QingYu pigs exhibited superior reproductive traits. The TNB available to QingYu pigs was more than 8 per parity. The observed repeatability of the reproductive traits of the QingYu pigs was between 0.10 and 0.23. The significantly correlated genetic and phenotypic of reproduction traits were consistent. Interestingly, the BQ pigs exhibited improved carcass quality, with a significant increase in loin muscle area, lean percentage and reduction in sebum percentage. As a result, BQ had higher L45min, lower cooking scores, and lower drip loss. In addition, the loin muscle area, body length, and sebum percentage were significantly higher in 90 and 100 kg animals. Cooking loss showed a significant increase at 80 kg, and marbling increased significantly from 90 kg. Conclusion: The results of this study suggest that QingYu pigs exhibit excellent reproductive properties and heritability of these traits. Crossing with Berkshire is an efficient strategy to improve the carcass and meat quality of QingYu pigs for commercial operations. Furthermore, it appears as though the optimal slaughter weight of BQ pigs is at approximately 90 kg.

여대생의 체형별 식품영양섭취와 식행동 (A Study on the Nutrient Intake and Eating Behaviors of the 3 Groups)

  • 이병순;이연숙
    • 한국식품영양학회지
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    • 제9권4호
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    • pp.441-446
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    • 1996
  • 본 연구는 여대생을 대상으로 야윈형(BMI 20 미만), 정상형(BMI 20∼25), 비만형(BMI 25 이상)을 각각 41, 48, 58명씩 총 147명을 선정하여 체형에 따른 식품 영양 섭취 실태와 식행동을 비교하여 다음과 같은 결론을 얻었다. 1. 1일 총 식품 섭취량중 아침과 간식은 체형간에 유의적인 차이를 나타냈다.(P<0.01) 한국인 영양 권장량에 비해 일부 영양소(야윈형은 단백질, 인, 정상형은 인, 비만형은 단백질, 인)만 권장량 이상을 섭취하였다. 모든 체형에서 대부분의 영양소량이 권장량 이하로 나타나 여대생의 영양섭취가 불균형으로 나타났다. 체형간에 유의적인 차이를 나타낸 영양소의 섭취는 단백질(p<0.01)과 칼슘(p<0.05)으로 단백질은 비만형이 가장 많이 섭취하였으나, 칼슘은 야윈형이 가장 만이 섭취하였다. 2. 모든 체형에서 열량은 영양권장량 이하로 섭취하였고, 체형간에 유의적인 차이는 나타나지 않았다. 그러나 간식으로부터의 열량섭취는 체형별 차이가 나타나 비만형이 간식으로부터 가장 많은 열량을 섭취하였다.(p<0.05) 3. 본인의 체형에 대한 인식은 체형간에 유의적인 차이는 없었지만 과소인식형보다 과대인식형이 더 많은 것으로 나타났다. 과대인식형은 야윈형에서 61.0%, 과소 인식형은 비만형에서 17.2%로 나타났다.(p<0.01) 4. 영양소 섭취에 직, 간접으로 영향을 주는 결식, 편식, 식사의 불규칙성에 대하여 자신의 인식 정도와 3일간의 식이섭취 조사에서 밝혀진 문제점을 비교한 결과, 편식에 대한 인식은 비교적 정확하였으나 결식과 식사의 불규칙성에 대한 인식은 정확하지 않았다. 이상과 같이 여대생은 자신의 식행동과 체형에 대한 인식이 정확하지 않았고 영양섭취도 대부분이 권장량 이하였으므로 앞으로 올바른 식생활을 위한 영양교육이 필요한 것으로 나타났다.

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재래종과 개량종 세절 돼지고기의 저장 중 품질 특성 비교 (Quality Comparison between Korean Native Black Ground Pork and Modern Genotype Ground Pork during Refrigerated Storage)

  • 이성기;주명규;김용선;강선문;최염순
    • 한국축산식품학회지
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    • 제25권1호
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    • pp.71-77
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    • 2005
  • 본 연구는 재래종 세절 돼지고기의 저장 중 품질 특성을 구명하기 위하여 개량종과 비교하여 실시하였다. 시험용 돼지고기로 240일간 사육된 평균체중 75 kg의 재래돼지와 210일간 사육된 평균체중 105 kg의 개량돼지를 이용하였다. 도축 후 세절돈육을 4℃에서 9일간 저장하며 실시하였다. 일반성분의 조성을 보면 재래종 돼지고기가 개량종에 비해 조지방과 조단백질 함량이 높고, 수분과 조회분 함량은 낮았다. 재래종 돼지고기의 pH가 개량종에 비해 저장 5일부터는 낮았고, 보수력은 저장기간 내내 유의적으로 높았다(p<0.05). 재래종 돼지고기는 명도가 낮고 적색도가 높아 개량종에 비해 검붉은 색깔을 지니고 있다. 저장기간이 늘어날수록 CIE L/sup */, a/sup */, b/sup */와 h/sup O/값들은 감소하는 경향을 보였다. TBARS, POV, FOX값 모두 저장기간이 증가할수록 유의적으로 증가하였으며 특히 재래종이 저장기간이 길어질수록 현저한 증가현상을 나타내었다. 재래종 돼지고기의 지방산 조성비율을 보면 총 포화지방산과 stearic acid 함량이 개량종에 비해 유의적으로 높았다(p<0.05).

소도사자환이 ob/ob mouse에서 ROS/ RNS 생성 억제 및 NF-${\kappa}B$ 의존성 단백질에 미치는 영향 (Effects of Sotosaja-hwan on the Generation of ROS, RNS, and on the Expression of NF-${\kappa}B$-dependent Proteins in ob/ob Mouse)

  • 방용석;정지천
    • 대한한의학회지
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    • 제30권1호
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    • pp.51-63
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    • 2009
  • Objectives: Peroxynitrite ($ONOO^-$), superoxide anion radical (${\cdot}{O_2}^-$ and nitric oxide (NO) are cytotoxic because they can oxidize several cellular components such as proteins, lipids and DNA. They have been implicated in the aging processes, and age-related diseases such as Alzheimer's disease, rheumatoid arthritis, cancer, diabetes, obesity and atherosclerosis. The aim of this study was to investigate the $ONOO^-$, NO, ${\cdot}{O_2}^-$ scavenging and NF-${\kappa}B$ related anti-inflammatory activities of Sotosaja-hwan in ob/ob mice. Methods: Mice were grouped and treated for 5 weeks as follows. Both the normal lean (C57/BL6J black mice) and control obese (ob/ob mice) groups have received standard chow. The experimental groups were fed with a diet of chow supplemented with 30 and 90 mg Sotosaja-hwan per 1 kg of body weight for 14 days. For this study, the fluorescent probes, namely 2',7'-dichlorodihydrofluorescein diacetate (DCFDA), 4,5-diaminofluorescein (DAF-2) and dihydrorhodamine 123 (DHR 123) were used. Western blotting was performed using anti-phospho-$I{\kappa}B$-${\alpha}$, anti-IKK-${\alpha}$, anti-NF-${\kappa}B$ (p50, p65), anti-COX-2, anti-iNOS, anti-YCAM-1 and anti-MMP-9 antibodies, respectively. Results: Sotosaja-hwan inhibited the generation of $ONOO^-$, NO and ${\cdot}{O_2}^-$ in the lipopolysaccharide (LPS)-treated mouse kidney postmitochondrial fraction in vitro. The generation of $ONOO^-$, NO, ${\cdot}{O_2}^-$ and PGE2 were inhibited in the Sotosaja-hwan-administered ob/ob mice groups. The GSH/GSSG ratio was decreased in the ob/ob mice, whereas the ratio was improved in the Sotosaja-hwan-administered groups. Sotosaja-hwan inhibited the protein expression levels of phospho-$I{\kappa}B$-${\alpha}$, IKK-${\alpha}$, NF-${\kappa}B$ (p50, p65), COX-2, iNOS, YCAM-1 and MMP-9 genes. Conclusions: These results suggest that Sotosaja-hwan is an effective $ONOO^-$, ${\cdot}{O_2}^-$ and NO scavenger and has NF-kB related anti-inflammatory activity in ob/ob mice. Therefore, Sotosaja-hwan might be a potential therapeutic drug against the inflammation process and inflammation-related diseases.

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Ursolic acid supplementation decreases markers of skeletal muscle damage during resistance training in resistance-trained men: a pilot study

  • Bang, Hyun Seok;Seo, Dae Yun;Chung, Young Min;Kim, Do Hyung;Lee, Sam-Jun;Lee, Sung Ryul;Kwak, Hyo-Bum;Kim, Tae Nyun;Kim, Min;Oh, Kyoung-Mo;Son, Young Jin;Kim, Sanghyun;Han, Jin
    • The Korean Journal of Physiology and Pharmacology
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    • 제21권6호
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    • pp.651-656
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    • 2017
  • Ursolic acid (UA) supplementation was previously shown to improve skeletal muscle function in resistance-trained men. This study aimed to determine, using the same experimental paradigm, whether UA also has beneficial effects on exercise-induced skeletal muscle damage markers including the levels of cortisol, B-type natriuretic peptide (BNP), myoglobin, creatine kinase (CK), creatine kinase-myocardial band (CK-MB), and lactate dehydrogenase (LDH) in resistance-trained men. Sixteen healthy participants were randomly assigned to resistance training (RT) or RT+UA groups (n=8 per group). Participants were trained according to the RT program (60~80% of 1 repetition, 6 times/week), and the UA group was additionally given UA supplementation (450 mg/day) for 8 weeks. Blood samples were obtained before and after intervention, and cortisol, BNP, myoglobin, CK, CK-MB, and LDH levels were analyzed. Subjects who underwent RT alone showed no significant change in body composition and markers of skeletal muscle damage, whereas RT+UA group showed slightly decreased body weight and body fat percentage and slightly increased lean body mass, but without statistical significance. In addition, UA supplementation significantly decreased the BNP, CK, CK-MB, and LDH levels (p<0.05). In conclusion, UA supplementation alleviates increased skeletal muscle damage markers after RT. This finding provides evidence for a potential new therapy for resistance-trained men.

알코올중독 아버지와 사는 자녀의 경험에 관한 연구 (The Lived Experience of Children of Alcohol Dependent Fathers)

  • 김명아
    • 한국보건간호학회:학술대회논문집
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    • 한국보건간호학회 2002년도 제27회 보건종합학술대회
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    • pp.224-227
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    • 2002
  • Alcoholism affects not only the individuals who depend on it, but also their families. Children who have an alcohol dependent parent have various problems and need help, but little attention has been given to them. Many references report only negative characteristics of these children. In order to help the children of alcohol dependent parents, health professionals need more information. A wholistic understanding and analysis of these children is needed as a basis for the development of suitable programs of help them. A phenomenological methodology was used to identify the experience of children whose fathers were addicted to alcohol. The findings portray the essence of the lived experience of children of alcohol dependent fathers. Nine adolescents participated in in-depth inverviews and observation with the researcher, done between October and December 2001. The data were recorded on audio tape and transcribed. Sampling was continued until the data were theorectically saturated. The Colaizzi's method was used for data analysis. The results of this study are as follows. Three themes and twenty six meanings were identified. The first theme is Living Alone: living abusively as partner to an alcohol dependent father, living dangerously like an explosive fury, living as an object that ha no self, living with rejection of fatherly being, living with felt responsibility but having no power to help mother who suffers patiently with pain and abuse, living along with no shoulder to lean on, and living with the prejudice of sex discrimination. The second theme is Paradoxical Coping in Life. The meanings are obsessive behavior as a way to control father's behavior, always on the defensive due to anxiety and tension, being afraid of life alone due to paranoid thoughts, contradictory expectation about father's drinking behavior due to life with chronic tension, stress becoming familiar and life being boring and tendious without stimulation, life that is fake and filled with misinterpretations about reality, affection sought from others due to loneliness, compensatory life within peer group, negative expectation about the future due to negative experiences, controling others to protect ego, denial of real emotion to protect self from hurt, life of regretting self, and strong need for approval from others. The third theme is sustaining life. The meanings are ambivalence between revenge on father and pity, struggle for desirable self against fear of gather-like image, understanding father through self reflection, hope to find fatherly being through father's recovery, being able to stand through emotional control and cognitive restructuring, nurturing the seed of hope for the future while in a situation of desperation. The contribution of this study is to give a wholistic understanding of the empirical reality of children of alcohol dependent parents and to develop substantive theory in nursing knowledge. In nursing practice, the results of this study can provide a foundation for the development of programs for children of alcohol dependent parents.

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친환경 레스토랑의 서비스스케이프가 소비자의 지각된 가치, 태도 및 행동의도에 미치는 영향 (The Effect of Servicescape of an Eco-friendly Restaurant on Customer Perceived Value, Attitude and Behavior Intention)

  • 최원식;이수범
    • 한국조리학회지
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    • 제18권5호
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    • pp.45-62
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    • 2012
  • 본 연구에서는 친환경 레스토랑의 서비스스케이프에 대한 고객의 인식을 조사하고, 분석하여 친환경 레스토랑의 물리적 환경을 고찰하기 위한 기초 자료를 확보하는데 그 목적이 있고, 친환경 레스토랑의 서비스스케이프와 소비자의 지각된 가치, 태도 및 행동의도에 유기적인 인과관계를 검증하고자 한다. 실증분석 대상자는 서울 경기 지역에 거주하고, 친환경 레스토랑 또는 그린 레스토랑에서 한 달에 1회 이상 방문해 본 경험이 있는 20세 이상 고객을 표본으로 선정하여, 2012년 4월 2일부터 2012년 4월 15일까지 14일간 본 조사를 위하여 설문지 총 300부를 배포하여 결과 응답치의 편중성향이 너무 강하거나 결측 값이 발견된 일부 설문지를 제외하고, 총 264부(88.0%)의 설문자료를 최종 통계 분석 자료로 사용하였다. 본 연구의 분석 결과를 보면 고객이 친환경 레스토랑의 서비스스케이프를 호의적으로 인지 하게 되면, 유 무형적인 지각된 가치를 통해서 소비자는 지각된 가치를 결정하는데 있어서 서비스스케이프가 중요한 역할을 하는 것으로 판단할 수 있으며, 소비자의 지각된 가치는 태도와 행동의도에 긍정적인 영향을 미치기 때문에 고객은 해당 친환경 레스토랑을 만족하면 행동의도에 영향을 미치는 것으로 판단되고, 긍정적인 태도는 행동의도에 영향을 미치는 것으로 사료된다. 따라서, 이러한 심층분석 결과를 바탕으로 경영자 입장에서 높은 수준의 서비스스케이프를 유지하고 제공하는 것이 외식 기업들의 가시적인 성과 도출에 직접적인 영향을 준다는 사실을 고찰하였다.

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Osteoporosis in Patients with Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome

  • Oh, Jee Youn;Lee, Young Seok;Min, Kyung Hoon;Lee, Sung Yong;Shim, Jae Jeong;Kang, Kyung Ho;Hur, Gyu Young
    • Tuberculosis and Respiratory Diseases
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    • 제81권1호
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    • pp.73-79
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    • 2018
  • Background: Osteoporosis is a common disease that occurs comorbidly in patients with chronic inflammatory airway diseases, including asthma, chronic obstructive pulmonary disease (COPD), and asthma-COPD overlap syndrome (ACOS). However, the prevalence of osteoporosis in patients with ACOS has not widely been evaluated. Therefore, we investigated the prevalence of osteoporosis and its relationship with the clinical parameters of patients with asthma, COPD, and ACOS. Methods: This was a retrospective, cross-sectional study. Bone mineral density (BMD), lung function tests, and disease status evaluations were conducted. Results: A total of 321 patients were enrolled: 138 with asthma, 46 with ACOS, and 137 with COPD. One hundred and ninety-three patients (60.1%) were diagnosed with osteoporosis (53.6% of asthma, 65.2% of ACOS, and 65.0% of COPD). Patients with ACOS showed a significantly lower BMD and T-score than did those with asthma. In addition to age, sex, and body mass index (BMI), which were previously reported to be associated with BMD, BMD also had a negative correlation with the diagnosis of ACOS, as compared to a diagnosis of asthma, after adjusting for age, sex, BMI, smoking, and inhaled corticosteroid use (p=0.001). Among those patients with COPD and ACOS, BMD was negatively associated with the COPD Assessment Test (CAT) after adjustment (p<0.001). Inhaled corticosteroid was not associated with the prevalence of osteoporosis and BMD. Conclusion: Patients with ACOS, particularly aged and lean women, should be more carefully monitored for osteoporosis as compared to patients with asthma.

입체 장애 알카놀아민 혼합 수용액에서 중탄산칼륨 결정의 냉각 반용매 결정화 (Cooling and Antisolvent Crystallization of Potassium Bicarbonate in the Presence of Sterically Hindered Alkanolamines)

  • 조창신;정태성;윤형철;김종남;이영우
    • 청정기술
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    • 제20권4호
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    • pp.383-389
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    • 2014
  • 이산화탄소 흡수공정은 대규모의 이산화탄소를 처리하는데 유리하지만, 다량의 흡수액을 재생하는데 필요한 현열과 증발열로 인한 에너지 비용 상승이 단점으로 지적되고 있다. 이를 극복하기 위해 이산화탄소를 흡수한 탄산칼륨 흡수액을 냉각 결정화시켜, 다량의 물로부터 이산화탄소가 많이 포함된 중탄산칼륨 결정을 선택적으로 분리할 수 있다. 본 연구에서는 이산화탄소 분리효율을 높이기 위해 입체 장애 알카놀아민 첨가제를 도입하여, 이들이 중탄산칼륨 연속식 결정화에 미치는 영향에 대해 살펴보았다. 결정의 석출량은 2-아미노-2-메틸-1-프로판올(2-amino-2-methyl-1-propanol, AMP), 2-아미노-2-메틸-1,3-프로판디올(2-amino-2-methyl-1,3-propanediol, AMPD), 2-아미노-2-히드록시메틸-1,3-프로판디올(2-amino-2-hydroxymethyl-1,3-propanediol, AHPD)의 순서로 증가하였으며, 반용매로 작용하는 첨가제들의 히드록실기 개수와 관계가 있는 것으로 나타났다. 탄소 핵자기공명분광 분석 결과, 첨가제들은 입체 장애 효과에 의해 중탄산 이온의 생성을 유도하고 과포화도를 상승시킨 것으로 나타났다. 또한, 첨가제들은 과포화도 상승을 통해 평균 입도와 결정 성장 속도를 증가시키는 것으로 나타났다. 입체 장애 알카놀아민 첨가제는 중탄산칼륨 결정화를 촉진함으로써, 물로부터 이산화탄소의 분리효율을 향상시키고 재생에너지를 저감시킬 수 있을 것으로 기대된다.