• Journal of the Korea Concrete Institute
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• v.19 no.6
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• pp.803-810
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• 2007

An analytical method capable of predicting various stress-strain responses in axially loaded concrete confined with FRP (fiber reinforced polymers) composites in a rational manner is presented. Its underlying idea is that the volumetric expansion due to progressive microcracking in mechanically loaded concrete is an important measure of the extent of damage in the material microstructure, and can be utilized to estimate the load-carrying capacity of concrete by considering the corresponding accumulated damage. Following from this, an elastic modulus expressed as a function of area strain and concrete porosity, the energy-balance equation relating the dilating concrete to the confining device interactively, the varying confining pressure, and an incremental calculation algorithm are included in the solution procedure. The proposed method enables the evaluation of lateral strains consecutively according to the related mechanical model and the energy-balance equation, rather than using an empirically derived equation for Poisson's ratio or dilation rate as in other analytical methods. Several existing analytical methods that can predict the overall response were also examined and discussed, particularly focusing on the way of considering the volumetric expansion. The results predicted by the proposed and Samaan's bilinear equation models correlated with observed results with a reasonable degree, however it can be judged that the latter is not capable of predicting the response of lateral strains correctly due to incorporating the initial Poisson's ratio and the final converged dilation rate only. Further, the proposed method seems to have greater benefits in other applications by the use of the fundamental principles of mechanics.

• Journal of Dental Rehabilitation and Applied Science
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• v.25 no.2
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• pp.171-181
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• 2009

The objective of this study was to analyse stress distribution of maxillary complex by use of face mask. The construction of the three-dimensional FEM model was based on the computed tomography(CT) scans of 13.5 years-old male subject. The CT image were digitized and converted to the finite element model by using the mimics program, with PATRAN. An anteriorly directed force of 500g was applied at the first premolar 45 degrees downwards to the FH plane and at the first molar 20 degrees downwards to the FH plane. When 45 degrees force was applied at maxillary first premolar, there were observed expansion at molar part and constriction at premolar part. The largest displacement was 0.00011mm in the x-axis. In the y-axis, anterior displacement observed generally 0.00030mm at maximum. In the z-axis, maxillary complex was displaced 0.00036 mm forward and downward. When 20 degrees force was applied at maxilla first molar, there were observed expansion at lateral nasal wall and constriction at molar part. The largest displacement was 0.001mm in the X-axis. In the Y-axis, anterior displacement observed generally 0.004mm at maximum. In the Z-axis, ANS was displaced upward and pterygoid complex was displaced downward. The largest displacement was 0.002mm.

• Applied Microscopy
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• v.18 no.2
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• pp.177-186
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• 1988

Degeneration of the axon terminals of mamillo-thalamic tract following the electrical coagulation of mamillary body is well known. In this study, the author investigated the ultrastructural alterations of neuropil components, initiated by terminal degenerations. Rats weighing approximately 250 gm were fixed on the stereotaxic instrument(David Kopf Inc., Heavy duty model), and NE 300 active electrode(Rhodes Med. Instr. Inc.) was introduced to the mamillary position of anterior 3.8 mm, lateral 0.5 mm, height 3.8 mm and lateral angle of $23^{\circ}$ according to De Groot's Atlas. Electric current of 20 mA was applied during 1 minute between active and inactive electrodes with Radio Frequency Lesion Generator(RFG 4, Radionics Inc.). Two hours, 2 days, 1 week and 2 weeks following the electrical coagulation of mamillary body, ipsilateral anterior thalamic nucleus was fixed in 1% glutaraldehyde-l% paraformaldehyde and 2% osmium tetroxide, embedded in Araldite mixture, cutted with LKB ultra tome V, stained with uranyl acetate-lead citrate and observed with JEOL 100 CX electron microscope. Observed results were as follows; 1. Degenerated mamillo-thalamic synapses were observed to form asymmetric axospinous or axo-dendritic types. 2. Terminal degeneration was not easily discernible at 2 hours interval after mamillary lesion, but following 2 days the terminal degeneration was apparent. 3. Postsynaptic spines, dendrites and even their cell bodies show edematic changes caused by the degeneration of postsynaptic counterpart. 4. Astrocytic territories, including perivascular processes forming glial limitans of blood-brain barrier, exhibit remarkable expansion. 5. Oligoglia and astroglia are actively engaged in the removal of degenerated elements. 6. Active forms of microglia were increased. 7. The observed results may represent typical ultrastructural alteration pattern within neuropil following the degeneration of certain input axon terminals.

• Molecules and Cells
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• v.43 no.9
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• pp.821-830
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• 2020

Altered dendritic morphology is frequently observed in various neurological disorders including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but the cellular and molecular basis underlying these pathogenic dendritic abnormalities remains largely unclear. In this study, we investigated dendritic morphological defects caused by dipeptide repeat protein (DPR) toxicity associated with G4C2 expansion mutation of C9orf72 (the leading genetic cause of ALS and FTD) in Drosophila neurons and characterized the underlying pathogenic mechanisms. Among the five DPRs produced by repeat-associated non-ATG translation of G4C2 repeats, we found that arginine-rich DPRs (PR and GR) led to the most significant reduction in dendritic branches and plasma membrane (PM) supply in Class IV dendritic arborization (C4 da) neurons. Furthermore, expression of PR and GR reduced the number of Golgi outposts (GOPs) in dendrites. In Drosophila brains, expression of PR, but not GR, led to a significant reduction in the mRNA level of CrebA, a transcription factor regulating the formation of GOPs. Overexpressing CrebA in PR-expressing C4 da neurons mitigated PM supply defects and restored the number of GOPs, but the number of dendritic branches remained unchanged, suggesting that other molecules besides CrebA may be involved in dendritic branching. Taken together, our results provide valuable insight into the understanding of dendritic pathology associated with C9-ALS/FTD.

• Archives of Craniofacial Surgery
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• v.12 no.1
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• pp.48-52
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• 2011

Purpose: Many advances have been made in lower eyelid reconstruction surgical procedures after tumor ablative therapy. These include skin grafts, local flaps, free flaps, and skin expansion. When a full-thickness defect of the lower eyelid is reconstructed with many free flaps, ectropion and deformity of the medial and lateral canthal areas are common late complications caused by gravitational descent. The radial forearm free flap is widely used because of its lack of bulk, ease of dissection, malleability, and hairlessness. This report introduces a novel method for preventing ectropion using a composite radial forearm free flap reconstruction and palmaris longus suspension technique. Methods: A 70-year-old man had a malignant melanoma on his left lower eyelid. The patient was referred to our department after a biopsy confirmed the initial diagnosis. A full-thickness wide resection with a 25 mm free margin was performed, and a $5{\times}8cm$ radial forearm flap was elevated with a vascularised palmaris longus tendon. The palmaris longus tendon was fixed to the medial and lateral orbital rim perisoteum and the deep temporal fascia. The buccal mucosa was grafted to reconstruct the inner conjunctival layer. The pedicle vessels were anastomosed to the left superficial temporal artery and vein. Results: The postoperative clinical course was uneventful. The flap showed good texture and color match. No ectropion was noted 14 months after surgery and the tumor did not recur. The patient was quite satisfied with the final outcomes. Conclusion: Use of a radial forearm free flap and the palmaris longus tendon is an effective method for a full-thickness lower eyelid reconstruction.

• The korean journal of orthodontics
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• v.17 no.2
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• pp.185-200
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• 1987

This paper was undertaken to observe the displacement of craniofacial complex with cervical headgear and to compare narrowing or widening effect of palate by use of contraction or expansion face-bow, respectively. The 3-dimensional finite element method(FEM) was used for a mathematical model composed of 597 nodes and 790 elements and an electrical resistance strain gauge investigation was performed to validate the finite element model. The outer bow of cervical headgear was adjusted to be placed below the occlusal plane by $25^{\circ}$ and met the midsagittal plane by $40^{\circ}$, and was loaded 1kg on each right and left hook toward posterior direction. The results were as follows 1. Generally, the maxillary teeth and facial bone were displaced in posterior, medial and downward direction. 2. It was the maxillary 2nd bicuspid that moved bodily. 3. The craniofacial complex rotated in a clockwise direction around the rotating axis which lay from the most posterior and lowest point connecting nasal crest of maxillary bone and vomer, progressively toward a more posterior, lateral and upward direction, anterior and upper area of pterygomaxillary fissure, base of medial pterygoid plate and laterally to the contact area of zygomatic arch with squamous part of temporal bone. 4. No contraction effect was observed by contraction face-bow when compared to the standard face-bow. 5. In case of expansion face-bow, the areas of maxillary 2nd bicuspid, molars and palate were expanded remarkably.

• Journal of the korean academy of Pediatric Dentistry
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• v.42 no.1
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• pp.87-101
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• 2015

The premature loss of the mandibular primary canine is relatively frequent and a sign of the upcoming space problems in the transitional period. This situation is caused by the permanent lateral incisor resorbing the root of the primary canine during its eruption. Bilateral loss of primary canines in a crowded arch leads to the lingual tipping of the permanent incisors, with the consequent reduction in the arch perimeter and increase in overbite. When the loss of a primary canine is unilateral, tipping of the adjacent incisors occurs toward the space, resulting in midline deviation. In these situations, treatment possibilities, such as extraction of the antimeric tooth or placement of a passive lingual arch, can be applied; although there are some controversies concerning this. Most space problems with less than 4 mm can be resolved through preservation of the leeway space using sequential disking of the primary teeth and a passive lingual arch, regaining space or limited arch expansion in the late mixed dentition. In cases with 4~6 mm of space problems, arch expansion (A-P or transverse) can be applied. Space problems with more than 6 mm should be treated through diagnosis and treatment planning. Most of these cases will require extraction of permanent teeth including serial extraction (guidance of eruption).

• The korean journal of orthodontics
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• v.42 no.5
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• pp.235-241
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• 2012

Objective: The purpose of this study was to evaluate the validity of the 3-dimensional (3D) superimposition method of digital models in patients who received treatment with rapid maxillary expansion (RME) and maxillary protraction headgear. Methods: The material consisted of pre- and post-treatment maxillary dental casts and lateral cephalograms of 30 patients, who underwent RME and maxillary protraction headgear treatment. Digital models were superimposed using the palate as a reference area. The movement of the maxillary central incisor and the first molar was measured on superimposed cephalograms and 3D digital models. To determine whether any difference existed between the 2 measuring techniques, intra-class correlation (ICC) and Bland-Altman plots were analyzed. Results: The measurements on the 3D digital models and cephalograms showed a very high correlation in the antero-posterior direction (ICC, 0.956 for central incisor and 0.941 for first molar) and a moderate correlation in the vertical direction (ICC, 0.748 for central incisor and 0.717 for first molar). Conclusions: The 3D model superimposition method using the palate as a reference area is as clinically reliable for assessing antero-posterior tooth movement as cephalometric superimposition, even in cases treated with orthopedic appliances, such as RME and maxillary protraction headgear.

• Journal of the Korean Society of Costume
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• v.58 no.2
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• pp.162-180
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• 2008

The purpose of this study is to find the basic design factors that affect the changes in body surface lines caused by lower limb movements, thereby resulting in slacks that fit well regardless of whether the human form is static or in motion. Using unmarried female university students aged 18-24 as subjects, a total of 32 body surface lines (15 body surface total lines and 17 body surface segment lines) were measured in one static and 9 movement poses, The analysis first involved the calculation of the expansion and contraction rates per body part in body surface line in 9 lower limb movements, Second, a factor analysis was conducted using the expansion and contraction rates of these changes in body surface line. The results of this study are as follows, According to the factor analysis, basic design factors that affect changes in body surface lines comprised 8 types of factors as illustrated in fig, 2-fig, 9, which explained 79.2% of total variate for the variables studied, Factor 1, comprising the lower segment of center back leg line, center front leg line and inner leg line, and lower limb girth except midway thigh girth and ankle girth below hip girth, accounted for 30.3% of total variance, Factor 2, comprising waist girth, the total and upper segment of center back leg line and center tront leg line, and front and back segment of crotch length, explained 17.4% of total variance, Factor 3, the total and upper segment of lateral leg line at the center, accounted for 56.5% of total variance in accordance with Factors 1, 2, and 3, Factor 4 was the contracting upper part of lower leg between legscye girth and midway thigh girth, Factor 5 comprised the total and upper segment of inner leg line and posterior knee girth, Factor 6 was the total crotch length, Factor 7 was the ankle girth, Factor 8 was the abdomen girth.

• Korean Journal of Cleft Lip And Palate
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• v.15 no.2
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• pp.69-82
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• 2012

Our Team Approach consists of following five stages; (1) Peri-natal care until lip repair After ultrasound diagnosis, some obstetricians recommend the mother with CL/P fetus to undergo prenatal counseling in our CLP clinic. On the day the CL/P baby was born, our oral surgeon, nurse, and pedodontist visit the maternity clinic, and take counseling and take impression for a feeding plate. The cheiloplasty is performed in three months old. (2) From lip repair to palatal repair At one year of age, Otorhinolaryngologist checks middle-ear disease. Palatoplasty is carried out at 1.5 - 2 years old. (3) In deciduous and early mixed dentitions Speech is the most important issue in social life for the CL/P subjects, therefore the training of velopharyngeal function is essential. Orthodontist monitors dentofacial development from 5 years of age. In the case of severe maxillary under-growth or severe collapse, maxillary protractor or lateral expansion is indicative, respectively. In early mixed dentition, upper central incisor on the cleft area erupts with some torsion, and then the traumatic occlusion with tooth torsion must be corrected. (4) In mixed dentition Right before the eruption of upper canines, secondary bone grafting is performed. One year prior to the operation, maxillary fan-type expansion is carried out to correct the collapse of maxillary segments. Following the surgical operation, the erupted canine will be moved into the transplanted bone to avoid alveolar resorption. (5) In permanent dentition Final tooth alignment is carried out after eruption of second molars. Some cases may require orthognathic surgery after physical maturation. Prosthetic oral rehabilitation including the dental-implant is carried out after age eighteen.