• 제목/요약/키워드: laboratory risk assessment

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연구실 위험성평가방법 개선에 관한 연구 (A Study on the Improvement of Risk Assessment Method in Laboratory)

  • 김수태
    • 한국재난정보학회 논문집
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    • 제18권3호
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    • pp.444-456
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    • 2022
  • 연구목적: 연구실험실에는 사전유해인자위험분석을 실시하도록 하고 있으나 실행하지 않는 연구실험실이 많다. 연구실험실의 안전을 확보하기 위한 목적으로 좀 더 쉽게 위험성평가를 적용 할 수 있도록 개선점을 찾고자 한다. 연구방법: 선행논문 및 과학기술정보통신부 연구실 안전관리 실태조사 보고서 자료를 활용하였다. 사전유해인자위험분석과 산업안전보건법에 의한 위험성평가를 비교하여 연구하였다. 연구결과: 연구실험실에 대한 위험성을 평가할 수 있는 기법을 제시하였다. 연구실험실 위험성평가시 가능성(빈도)과 중대성(강도)의 크기를 추정할 수 있도록 방법을 제시하였다. 결론: 연구실험실에서 쉽게 적용할 수 있도록 체크리스트 형태의 위험성평가 기법을 제시하였고, 실제 평가해 보았다. 연구실험실에서 위험성평가를 통한 개선을 실시하여 안전사고 예방에 도움이 될 것으로 기대한다.

연구실 사전유해인자위험분석 적용방안 및 제도도입 연구 (A Study on Application Method & System Introduction of Laboratory Pre-hazards Risk Analysis)

  • 조남준;지용구
    • 한국안전학회지
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    • 제31권4호
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    • pp.126-135
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    • 2016
  • The purpose of this study is to develop risk assessment techniques and institutional analysis of domestic and international, the management techniques that can efficiently manage the harmful factor of the laboratory and to present the institutional measures that can be efficiently implemented. Due to a variety of adverse factors of laboratory, accidents of laboratory of various forms have occurred, but there is no risk assessment system in order to manage this effectively. So, we investigated this domestic existing risk assessment methods and the outside of the risk assessment system, and also analyzed accidents of domestic laboratory that occurred in 2014. In addition, we targeted the 24 laboratories in 21 universities to investigate the management of harmful factors of the laboratory and performed applying test for 12 domestic laboratories. Existing risk evaluation system, such as PMS, SMS, off-site impact assessment, since the industrial site is the subject, is a difficult problem to be directly applied to the laboratory of the research institute. So, we implemented management status and harmful factors survey and classified the research and development activities based on this data. Finally we developed "pre-hazards risk analysis method" to create each of the safety management measures. In addition, research activities personnel conducted voluntarily risk assessment, which is shared by institutions and government. It is presented the institutional system for safety management of laboratory. Its result, pre-hazards risk analysis method and institutionalization scheme will be able to achieve laboratory accident prevention system.

연구실 위험분석을 위한 사전유해인자 가이드 Tool 개발 연구 (A Study on Development of Pre-Hazards Risk Analysis Guide Tool)

  • 최병규;이광원
    • 대한안전경영과학회지
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    • 제19권4호
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    • pp.133-140
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    • 2017
  • The Ministry of Science, ICT and Future Planning made law for Pre-Hazard Risk Analysis in December 31, 2014 to protect researchers from continuing accidents in laboratory. Conducted before an experiment, Pre-Hazard Risk Analysis finds hazards of the experiment and rules to manage the hazards.So the Pre-Hazard Risk Analysis can support laboratory safety system by prevent accidents in laboratory. Pre-Hazards Risk Analysis is newly created system so that executors need Guidelines to perform this analysis properly. This study is to develop guide tool for Pre-Hazard Risk Analysis by analyzing other risk assessment systems; PSM, Off-site Consequence Assessment, laboratory safety system. Also, this study suggested how to establish database for Pre-Hazard Risk Assessment by analyse KRAS.

Assessment of Chemical Risks in Moroccan Medical Biology Laboratories in Accordance with the CLP Regulation

  • Mourry, Ghita E.;Alami, Rachid;Elyadini, Adil;Hajjaji, Souad El;kabba, Saad El;Zouhdi, Mimoun
    • Safety and Health at Work
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    • 제11권2호
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    • pp.193-198
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    • 2020
  • Background: Medical laboratory workers are frequently exposed to a wide range of chemicals. This exposure can have adverse effects on their health. Furthermore, a knowledge lack of the chemical risk increases the likelihood of exposure. The chemical risk assessment reduces the risk of exposure to hazardous chemicals and therefore, guarantees health and safety of the workers. Method: The chemical risk assessment was conducted using a modified INRS method, according to the new CLP Regulation, of 11 unit laboratories in a Moroccan medical laboratory. Observation of each workstation and analysis of safety data sheets are key tools in this study. Results: A total of 144 substances and reagents that could affect the health of the analytical technicians were identified. Among these products, 17% are concerned by the low priority risk score, with 55% concerned by the average priority risk score and 28% concerned by the high priority risk score. This study also enabled to better identify the chemical agents that have restrictive occupational exposure limit value and controls were conducted to this effect. On the basis of the results obtained, several corrective and preventive measures have been proposed and implemented. Conclusion: Risk assessment is essential to ensure the health and safety of workers and to meet regulatory requirements. It enables to identify all the risky manipulations and to adopt appropriate preventive measures. However, it is not a one-time activity but it must be continuous in order to master the changes and thus ensure the best safety of all.

Risk identification, assessment and monitoring design of high cutting loess slope in heavy haul railway

  • Zhang, Qian;Gao, Yang;Zhang, Hai-xia;Xu, Fei;Li, Feng
    • Structural Monitoring and Maintenance
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    • 제5권1호
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    • pp.67-78
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    • 2018
  • The stability of cutting slope influences the safety of railway operation, and how to identify the stability of the slope quickly and determine the rational monitoring plan is a pressing problem at present. In this study, the attribute recognition model of risk assessment for high cutting slope stability in the heavy haul railway is established based on attribute mathematics theory, followed by the consequent monitoring scheme design. Firstly, based on comprehensive analysis on the risk factors of heavy haul railway loess slope, collapsibility, tectonic feature, slope shape, rainfall, vegetation conditions, train speed are selected as the indexes of the risk assessment, and the grading criteria of each index is established. Meanwhile, the weights of the assessment indexes are determined by AHP judgment matrix. Secondly, The attribute measurement functions are given to compute attribute measurement of single index and synthetic attribute, and the attribute recognition model was used to assess the risk of a typical heavy haul railway loess slope, Finally, according to the risk assessment results, the monitoring content and method of this loess slope were determined to avoid geological disasters and ensure the security of the railway infrastructure. This attribute identification- risk assessment- monitoring design mode could provide an effective way for the risk assessment and control of heavy haul railway in the loess plateau.

Isolation and Characterization of Bacillus sp. Producing Broad-Spectrum Antibiotics Against Human and Plant Pathogenic Fungi

  • Chen, Na;Jin, Min;Qu, Hong-Mei;Chen, Zhi-Qiang;Chen, Zhao-Li;Qiu, Zhi-Gang;Wang, Xin-Wei;Li, Jun-Wen
    • Journal of Microbiology and Biotechnology
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    • 제22권2호
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    • pp.256-263
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    • 2012
  • A strain of bacterium producing antifungal antibiotic was isolated and identification of the strain was attempted. We could identify the bacterium as being a Bacillus sp., based on morphological observation, physiological characteristics, and 16S rDNA sequence analysis, thus leading us to designate the strain as Bacillus sp. AH-E-1. The strain showed potent antibiotic activity against phytopathogenic and human pathogenic fungi by inducing mycelial distortion and swelling and inhibiting spore germination. The antibiotic metabolite produced by the strain demonstrated excellent thermal and pH (2-11) stability, but was labile to autoclaving. From these results, we could find a broader antifungal activity of Bacillus genus. Isolation and characterization of the active agent produced by the strain are under progress.

A rapid modeling method and accuracy criteria for common-cause failures in Risk Monitor PSA model

  • Zhang, Bing;Chen, Shanqi;Lin, Zhixian;Wang, Shaoxuan;Wang, Zhen;Ge, Daochuan;Guo, Dingqing;Lin, Jian;Wang, Fang;Wang, Jin
    • Nuclear Engineering and Technology
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    • 제53권1호
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    • pp.103-110
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    • 2021
  • In the development of a Risk Monitor probabilistic safety assessment (PSA) model from the basic PSA model of a nuclear power plant, the modeling of common-cause failure (CCF) is very important. At present, some approximate modeling methods are widely used, but there lacks criterion of modeling accuracy and error analysis. In this paper, aiming at ensuring the accuracy of risk assessment and minimizing the Risk Monitor PSA models size, we present three basic issues of CCF model resulted from the changes of a nuclear power plant configuration, put forward corresponding modeling methods, and derive accuracy criteria of CCF modeling based on minimum cut sets and risk indicators according to the requirements of risk monitoring. Finally, a nuclear power plant Risk Monitor PSA model is taken as an example to demonstrate the effectiveness of the proposed modeling method and accuracy criteria, and the application scope of the idea of this paper is also discussed.

건축물의 화재위험의 분석과 지수화에 관한 연구 (A Study on Fire Risk Analysis & Indexing of Buildings)

  • 정의수;양광모;하정호;강경식
    • 대한안전경영과학회지
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    • 제10권4호
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    • pp.93-104
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    • 2008
  • A successful fire risk assessment is depends on identification of risk, the analytical process of potential risk, on estimation of likelihood and the width and depth of consequence. Take the influence on enterprise into consideration, Fire risk assessment could carry out along the evaluation of the risk importance, the risk level and the risk acceptance. A large part of the limitation of choosing the risk assessment techniques impose restrictions on expense and time. If it is unnecessary high level risk assessment or Probabilistic Risk Assessment of buildings, in compliance with the Relative Ranking Method, Fire risk indexing and assessing is possible. As working-level technique, AHP method is useful with practical technique.

Diversity of Arbuscular Mycorrhizal Fungi Associated with a Sb Accumulator Plant, Ramie (Boehmeria nivea), in an Active Sb Mining

  • Wei, Yuan;Chen, ZhiPeng;Wu, FengChang;Li, JiNing;ShangGuan, YuXian;Li, FaSheng;Zeng, Qing Ru;Hou, Hong
    • Journal of Microbiology and Biotechnology
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    • 제25권8호
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    • pp.1205-1215
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    • 2015
  • Arbuscular mycorrhizal fungi (AMF) have great potential for assisting heavy metal hyperaccumulators in the remediation of contaminated soils. However, little information is available about the symbiosis of AMF associated with an antimony (Sb) accumulator plant under natural conditions. Therefore, the objective of this study was to investigate the colonization and molecular diversity of AMF associated with the Sb accumulator ramie (Boehmeria nivea) growing in Sb-contaminated soils. Four Sb mine spoils and one adjacent reference area were selected from Xikuangshan in southern China. PCR-DGGE was used to analyze the AMF community composition in ramie roots. Morphological identification was also used to analyze the species in the rhizosphere soil of ramie. Results obtained showed that mycorrhizal symbiosis was established successfully even in the most heavily polluted sites. From the unpolluted site Ref to the highest polluted site T4, the spore numbers and AMF diversity increased at first and then decreased. Colonization increased consistently with the increasing Sb concentrations in the soil. A total of 14 species were identified by morphological analysis. From the total number of species, 4 (29%) belonged to Glomus, 2 (14%) belonged to Acaulospora, 2 (14%) belonged to Funneliformis, 1 (7%) belonged to Claroideoglomus, 1 (7%) belonged to Gigaspora, 1 (7%) belonged to Paraglomus, 1 (7%) belonging to Rhizophagus, 1 (7%) belonging to Sclervocystis, and 1 (7%) belonged to Scutellospora. Some AMF sequences were present even in the most polluted site. Morphological identification and phylogenetic analysis both revealed that most species were affiliated with Glomus, suggesting that Glomus was the dominant genus in this AMF community. This study demonstrated that ramie associated with AMF may have great potential for remediation of Sb-contaminated soils.