• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제22권3호
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• pp.7-15
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• 2016

Purpose: As medicare services have gotten spreaded, clinical laboratory has been dominant position. So, it has been acted for quality control and clinical pathology accreditation. But there has been quite deficient information to evaluate working space and technical standards of medical laboratory for accreditation. This study goals to figure out accreditation standard and design guideline for clinical laboratory, and to give safe and efficient design information. Methods: This study has been searched by literature for accreditation standards and design guidelines of clinical pathology in USA, UK, and Germany. Results: Three countries have accredited based on working lab space, staff space, storage space, patient space and health and safety equipment. Design guidelines of three countries commonly have focused on worktable layout, worktable distance and module, and specific laboratory biosafety level. And USA guidelines stress on the architectural design such as design process and passage distance for escape, UK stress on the efficiency as functional work flow and construction cost, lastly Germany design guidelines stress on the operator's safety distance and workstation. Three countries have not only accreditation standards but also design guidelines for more specific quality management, separating from accrediting institute. Implications: In korea, it has been needed to make clinical laboratory design guideline for the safe and efficient environment and reliable and competitive medical service.

• 전자공학회논문지
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• 제51권10호
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• pp.197-203
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• 2014

신관 안전장전장치는 비행체의 수송, 저장, 취급 중의 안전을 절대적으로 보장하도록 설계되어야 한다. 본 논문에서는 비행체에 적용되는 신관 안전장전장치의 안전성을 증대시키기 위한 솔레노이드 조립체와 솔레노이드 조립체를 구동하기 위한 솔레노이드 구동회로를 포함한 신관 안전장전장치 설계에 대해 기술한다. 솔레노이드 조립체는 신관 안전장전장치에 적용한 추가적인 안전장치로서, 코일 조립체, 복원스프링, 코어 등으로 구성된다. 솔레노이드 조립체의 코어는 평상시에는 1차 안전장치를 구속하고 있어 1차 안전장치가 작동하는 것을 저지해줌으로써 비행체의 취급이나 수송 시 안전을 확보해주게 되며, 발사를 위한 비행체 배터리 전원이 인가 및 활성화되어 신관 안전장전장치에 공급되면, 솔레노이드 구동회로가 코어를 작동시켜 신관 안전장전장치의 1차 및 2차 안전장치를 해제시키는 역할을 한다. 또한, 솔레노이드 구동회로는 비행체 발사 이후, 신관 안전장전장치의 기계적 장전이 완료되어 장전스위치가 turn-on되면 솔레노이드 조립체에 인가되는 전원을 자동 차단시켜 비행 중의 전원 소모량을 줄일 수 있도록 하였다.

• 한국전자파학회논문지
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• 제29권12호
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• pp.942-952
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• 2018

국내에서 개발되고 있는 도시철도용 무선 전달 공급 시스템은 60 kHz 자기장을 이용하여 객차에 전력을 공급한다. 무선 전력 전송 시 발생되는 전자기장에 인체가 노출될 때, 전자기장 세기는 인체 안전성 기준을 만족해야 한다. 하지만 도시철도용 무선 급집전 시스템에서 발생하는 전자기장에 대한 측정 방법과 인체 안전성 평가 방법이 아직 확립되지 않았다. 본 논문에서는 도시철도용 무선 급집전 시스템에서 발생되는 전자기장 측정 방법 및 인체 안전성 평가 방법을 제안하였다. 제안된 측정 방법에 따라 무선 급집전 시스템 시험선로에서 발생되는 전자기장을 측정하고, 전자기장 인체 보호기준치와 비교하였다.

• International Journal of Fluid Machinery and Systems
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• 제9권4호
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• pp.332-337
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• 2016

Turbocompounding is a key technology to satisfy the future requirements of diesel engine's fuel economy and emission reduction. A turbocompound diesel engine was developed based on a conventional 11-Liter heavy-duty diesel engine. The turbocompound system includes a power turbine, which is installed downstream of a Variable Geometry Turbocharger (VGT) turbine. The impacts of the VGT rack position on the turbocompound engine performance were studied. An optimal VGT control strategy was determined. Experimental results show that the turbocompound engine using the optimal VGT control strategy achieves better performance than the original engine under all full load operation conditions. The averaged and maximum reductions of the brake specific fuel consumption (BSFC) are 3% and 8% respectively.

• 대한조선학회논문집
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• 제42권2호
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• pp.98-104
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• 2005

The mathematical models of hydrodynamic force and moment acting on a ship at low speed range should be established differently from the ones at nominal cruising speed range since a ship moves with large drift angle or rotates in a stationary position. We modified widely used Yoshimura's cross flow model in order to apply the system identification method to estimate parameters in the model. The apparatus and the procedure of free running model test were suggested so that the parameters in the model be estimated. The validity of our proposing modified model and test procedure was confirmed by comparison with the results of simulated model test.

• 대한약침학회지
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• 제25권2호
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• pp.121-129
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• 2022

Objectives: The chemical composition of cactus pear seed oil (Opuntia ficus-indica [L.] Mill.) was analyzed in terms of its fatty acid composition, tocopherol content, phenolic identification, and the oil's phenolic-rich fraction antioxidant power was determined. Methods: Fatty acid profiling was performed by gas chromatography coupled to an FI detector. Tocopherols and phenolic compounds were analyzed by LC-FLD/UV, and the oil's phenolic-rich fraction antioxidant power was determined by phosphomolybdenum, DPPH assay and β-carotene bleaching test. Results: Fatty acid composition was marked by a high unsaturation level (83.22 ± 0.34%). The predominant fatty acid was linoleic acid (66.79 ± 0.78%), followed by oleic acid (15.16 ± 0.42%) and palmitic acid (12.70 ± 0.03%). The main tocopherol was γ-tocopherol (172.59 ± 7.59 mg/kg. In addition, Tyrosol, vanillic acid, vanillin, ferulic acid, pinoresinol, and cinnamic acid were identified as phenolic compounds in the analyzed seed oil. Moreover, the oil's phenolics-rich fraction showed a significant total antioxidant activity, scavenged DPPH up to 97.85%, and effectively protected β-carotene against bleaching (97.56%). Conclusion: The results support the potential use of cactus pear seed oil as a functional food.

• 한국응용곤충학회지
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• 제57권4호
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• pp.243-251
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• 2018

꽃매미벼룩좀벌(Anastatus orientalis)을 실내에서 대량사육 할 수 있는 대체기주를 선발하기 위하여 꽃매미와 썩덩나무노린재(Halyomopha halys), 톱다리개미허리노린재(Riptortus pedestris), 매미나방(Lymantria dispar), 참나무산누에나방(Antheraea yamamai), 귀뚜라미(Verlarifictorus spp.), 집파리(Musca domestica), 산누에나방(Antheraea pernyi) 총 8 종의 알 또는 번데기를 이용하여 검토하였다. 그 결과 꽃매미 알과 산누에나방의 미성숙 알에서는 꽃매미벼룩좀벌의 산란과 우화가 확인되었으나 그 밖에 종의 알과 번데기에서는 산란을 확인할 수 없었다. 대체기주로 선발된 산누에나방은 참나무 잎으로 사육하였으며, 7월과10월 상순에 번데기를 수확하여 우화 후 4~5일경에 복부가 불룩한 산란 직전의 암컷 성충만을 선발하여 $1{\sim}5^{\circ}C$ 냉장고에 보관하였으며, 저온에 보관했던 암컷의 복부를 절개하여, 암컷 한 마리당 150~200개의 알을 얻었다. 꽃매미 알과 산누에나방의 미성숙 알에서 꽃매미벼룩좀벌의 발육기간은 각각 평균 36.8일과 36.1일이었으며, 24시간동안 암컷 한 마리가 산란한 알의 수는 각각 평균 4.2개와 3.4개로 통계적으로는 유의한 차이가 없었다. 한편, 꽃매미벼룩좀벌 암컷 성충의 수명은 벌꿀을 먹이로 제공 하였을 때, 평균 64.3일까지 생존하는 것으로 확인되었다. 산누에나방의 미성숙 알을 대량으로 확보하고 벌꿀을 먹이로 제공하면 꽃매미벼룩좀벌을 실내에서 대량사육 하는 것이 가능하고 야외방사를 통해 꽃매미의 생물적 방제에 활용할 수 있을 것으로 기대된다.

• Journal of Ginseng Research
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• 제44권2호
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• pp.222-228
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• 2020

Background: 20(S)-ginsenoside-Rg3 (C₄₂H₇₂O₁₃), a natural triterpenoid saponin, is extracted from red ginseng. The increasing use of 20(S)-ginsenoside Rg3 has raised product safety concerns. Methods: In acute toxicity, 20(S)-ginsenoside Rg3 was singly and orally administrated to Kunming mice and Sprague-Dawley (SD) rats at the maximum doses of 1600 mg/kg and 800 mg/kg, respectively. In the 26-week toxicity study, we used repeated oral administration of 20(S)-ginsenoside Rg3 in SD rats over 26 weeks at doses of 0, 20, 60, or 180 mg/kg. Moreover, a 4-week recovery period was scheduled to observe the persistence, delayed occurrence, and reversibility of toxic effects. Results: The result of acute toxicity shows that oral administration of 20(S)-ginsenoside Rg3 to mice and rats did not induce mortality or toxicity up to 1600 and 800 mg/kg, respectively. During a 26-week administration period and a 4-week withdrawal period (recovery period), there were no significant differences in clinical signs, body weight, food consumption, urinalysis parameters, biochemical and hematological values, or histopathological findings. Conclusion: The mean oral lethal dose (LD₅₀) of 20(S)-ginsenoside Rg3, in acute toxicity, is above 1600 mg/kg and 800 mg/kg in mice and rats, respectively. In a repeated-dose 26-week oral toxicity study, the no-observed-adverse-effect level for female and male SD rats was 180 mg/kg.

• Asian-Australasian Journal of Animal Sciences
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• 제31권6호
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• pp.835-841
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• 2018

Objective: The aim of this study was to investigate the reversibility and safety of KISS1 metastasis suppressor (KISS1) gene vaccine in immunocastration. Methods: Six eight-week old ram lambs were randomly divided into vaccinated and control groups. The vaccine (1 mg/ram lamb) was injected at weeks 0, 3, and 6 of the study. Blood samples were collected from the jugular vein before primary immunization and at weeks 2, 4, 6, 10, 14, 22, and 30 after primary immunization. All ram lambs were slaughtered at 38 weeks of age, and samples were collected. Results: The specific anti-KISS1 antibody titers in vaccinated animals were significantly higher and the serum testosterone level was significantly lower than those in the control groups from week 4 to 14 after primary immunization (p<0.05). No significant difference was observed at weeks 22 and 30 after the primary immunization. Similar results were also found for scrotal circumference, testicular weight, length, breadth, and spermatogenesis in seminiferous tubules in week 30 after primary immunization. KS (KISS1-hepatitis B surface antigen S) fusion fragment of KISS1 gene vaccine was not detected in host cell genomic DNA of 9 tissues of the vaccinated ram lambs by polymerase chain reaction. Conclusion: The effects of KISS1 gene vaccine in immunocastration were reversible and no integration events were recorded.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2004년도 한국우주과학회보 제13권2호
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• pp.106-106
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• 2004