• Parasites, Hosts and Diseases
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• v.53 no.2
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• pp.237-242
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• 2015

Analysis of ancient DNA (aDNA) extracted from Ascaris is very important for understanding the phylogenetic lineage of the parasite species. When aDNAs obtained from a Joseon tomb (SN2-19-1) coprolite in which Ascaris eggs were identified were amplified with primers for cytochrome b (cyt b) and 18S small subunit ribosomal RNA (18S rRNA) gene, the outcome exhibited Ascaris specific amplicon bands. By cloning, sequencing, and analysis of the amplified DNA, we obtained information valuable for comprehending genetic lineage of Ascaris prevalent among pre-modern Joseon peoples.

• Journal of Korean Medical classics
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• v.20 no.1
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• pp.65-74
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• 2007

"The Golden Mirror of Medicine(醫宗金鑑)" was compiled by the medical officers of the Qing government, headed by Wu-Qian(吳謙)."The Elimination &Supplement about the Famous Prescription Comments(刪補名醫方論)", a collection of notes written by famous scholars, is one part of "The Golden Mirror of Medicine(醫宗金鑑)" . Through the translation and comparative study of invigorative prescription(補氣方劑) in "The Elimination & Supplement about the Famous Prescription Comments(刪補名醫方論)" of "The Golden Mirror of Medicine(醫宗金鑑)" with "The Famous Prescription Comments on Ancient and Modem Times(古今名醫方論)" , we confirmed that many sentences of "The Famous Prescription Comments on Ancient and Modern Times(古今名醫方論)" were quoted, but that most of the text was not quoted as the same: it was revised and supplemented. In organization, invigoration prescriptions are placed at the head of the chapter, indicating their importance. In classification, prescriptions for reinforcing middle-jiao(中焦) and replenishing qi(補中益氣湯類 方劑) were usually included in the invigoration prescriptions(補氣方劑), which is explained in chapter II, thereby clearly distinguishing between treatments of deficiency of qi(氣虛) and combining it with the sinking of qi of middle-jiao(中氣下陷).

• Journal of Acupuncture Research
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• v.19 no.4
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• pp.42-48
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• 2002

Background : There are many books on ancient medicine among the Dunhuang books found at a cave in Dunhuang, most of which were transcribed during Tang dynasty, reflecting ancient theories and practices. Objective and Material : To investigate the usage of the terms of three pairs of yin and yang as acupoint names, 4 books on acupuncture and moxibustion among Dunhuang books were examined. Results and Conclusion : Investigation of the usage of the terms of three pairs of yin and yang in the scripts and illustrations of 4 Dunhuang books which are also the names of 12 main meridians revealed that the terms of three pairs of yin and yang were used as the names of specific acupoints so called three pairs of yin and yang acupoints. The significance of the terms of three pairs of yin and yang as the names of specific acupoints are discussed focusing on the early form and development of meridian theory.

• The Journal of the Korean bone and joint tumor society
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• v.19 no.1
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• pp.37-41
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• 2013

Ancient schwannoma is a variant of schwannoma and is characterized slowly growing tumor with degenerative change. And it is reported that schwannoma is relatively rare in extensor area. As a rare cause of solitary ancient schwannoma in extensor area of upper arm, we report it.

• Parasites, Hosts and Diseases
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• v.52 no.5
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• pp.569-573
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• 2014

In a paleo-parasitological analysis of soil samples obtained from V-shaped pits dating to the ancient Baekje period in Korean history, we discovered Ascaris lumbricoides, Trichuris trichiura, and Clonorchis sinensis eggs. In light of the samples' seriously contaminated state, the V-shaped pits might have served as toilets, cesspits, or dung heaps. For a long period of time, researchers scouring archaeological sites in Korea have had difficulties locating such structures. In this context then, the present report is unique because similar kind of the ancient ruins must become an ideal resource for successful sampling in our forthcoming paleoparasitological studies.

• Anatomy and Cell Biology
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• v.56 no.1
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• pp.54-60
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• 2023

Lactase non-persistence (LNP), one of the causes of lactose intolerance, is related to lactase gene associated single nucleotide polymorphisms (SNPs). Since the frequency of LNP varies by ethnic group and country, the research to reveal the presence or absence of LNP for specific people has been conducted worldwide. However, in East Asia, the study of lactase gene associated SNPs have not been sufficiently examined so far using ancient human specimens from archaeological sites. In our study of Joseon period human remains (n=14), we successfully revealed genetic information of lactase gene associated SNPs (rs1679771596, rs41525747, rs4988236, rs4988235, rs41380347, rs869051967, rs145946881 and rs182549), further confirming that as for eight SNPs, the pre-modern Korean people had a lactase non-persistent genotype. Our report contributes to the establishment of LNP associated SNP analysis technique that can be useful in forthcoming studies on human bones and mummy samples from East Asian archaeological sites.

• Korean Journal of Oriental Medicine
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• v.13 no.3
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• pp.185-189
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• 2007

As adjacent nations, China and Chosun was a part of the same cultural area and exchanged information on many different fields. The same was true for the medical field as well. Medical books published in China were republished in Korea and vice versa. While doing so the two nations greatly influenced each other's medical fields. The following study is a result of researching the medical books published in Chosun and analyzing how they influenced Chinese Traditional Medicine.

• Carbon letters
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• v.6 no.4
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• pp.255-256
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• 2005

In traditional Chinese medicine, some herbs are used after toasting or roasting. The process is called "Zhi Tan" in Chinese, which means charring, and the herbs after the treatment is called carbon medicine. Carbon medicine is widely used to arrest bleeding in traditional Chinese medicine. The paper introduces the records, development and applications of carbon medicine in ancient China. The earliest record found about carbon medicine was in the remains of Han dynasty (BC206-A.D.8). The paper also introduces the process of charring herbs and mechanism of carbon medicine in arresting bleeding. Calcium iron and tan released during the charring are believed as main factors for arresting bleeding, helped with porous surface structure of active carbon.

• BMB Reports
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• v.43 no.2
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• pp.133-139
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• 2010

We have performed analyses using ancient DNA extracted from 25 excavated human bones, estimating around the 1st century B.C. Ancient human bones were obtained from Nukdo Island, which is located off of the Korean peninsula of East Asia. We made concerted efforts to extract ancient DNA of high quality and to obtain reproducible PCR products, as this was a primary consideration for this extensive kind of undertaking. We performed PCR amplifications for several regions of the mitochondrial DNA, and could determine mitochondrial haplogroups for 21 ancient DNA samples. Genetic information from mitochondrial DNA belonged to super-haplogroup M, haplogroup D or its sub-haplogroups (D4 or D4b), which are distinctively found in East Asians, including Koreans or Japanese. The dendrogram and principal component analysis based on haplogroup frequencies revealed that the Nukdo population was close to those of the East Asians and clearly distinguished from populations shown in the other regions. Considering that Nukdo is geologically isolated in the southern part of the Korean peninsula and is a site of commercial importance with neighboring countries, these results may reflect genetic continuity for the habitation and migration of ethnic groups who had lived in a particular area in the past. Therefore, we suggest that phylogenetic analyses of ancient DNA have significant advantages for clarifying the origins and migrations of ethnic groups, or human races.

• Journal of Korean Medical classics
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• v.22 no.2
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• pp.275-283
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• 2009

The "Naegyeongseupyubangron(內經拾遺方論)", written by Nakyonggil(駱龍吉), is an ancient book of Bangron(方論). The exact time period of this book is unknown. To estimate its written time, we compared the contents of this book to other sources on the cause of diseases, the description of symptoms, the transmission of diseases, and treatments. In addition, we analyzed the features of the book by comparing it to other books of Bangron(方論). As a result, we estimated the approximate time period that it was written and gained a better understanding of the ancient medicine. We reached several conclusions through this study. 1. The approximate time period of "Naegyeongseupyubangron(內經拾遺方論)" is that of the Southern Song(南宋) dynasty of China, probably after "Saminbang(三因方)" between 1174 and 1279. 2. Nakyonggil(駱龍吉) was influenced by Wangbing(王冰), Sonsamak(孫思邈), Yuhagan(劉河間), Jinmutaek(陳無擇). and he influenced "Uibanggo(醫方考)". 3. The "Naegyeongseupyubangron(內經拾遺方論)" is the most comprehensive book among the books of Bangron(方論) because of its analysis of the "Hwangjenaegyeong(黃帝內經)" and its connection to the treatment of ancient diseases in Oriental Medical History.