• Korean Journal of Food Science and Technology
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• v.29 no.6
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• pp.1269-1274
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• 1997

This study was researched to purify and characterize variety bioactive material acethylmannan from Aloe vera. Purified acethylmannan was mannose (67%), acetyl group (23%) and the rest glucose, galactose that consisting of long chain polydispered ${\beta}-1,4$ linked mannan polymers. The sugar and acetyl group in molecular were linked molar ration one third. $IC_{50}$ value (i.e that concentration which exhibits 50% more enzyme inhibition than control) on angiotensin converting enzyme were 0.58 mM. This compound were found to be a competitive inhibition of Angiotensin Converting Enzyme with apparent Ki values of 0.068 mM.

• The Korean Journal of Nuclear Medicine
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• v.26 no.1
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• pp.111-115
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• 1992

Miliary Tuberculosis is an illness produced by acute dissemination of tubercle bacilli via the blood stream. In chest roentgenogram, a diffuse "miliary" infiltrates are usually seen, but normal or suspicious ground glass pattern also can be seen in early manifestation. Ten patients of miliary tuberculosis who underwent whole-body $^{67}Ga-citrate$ scintigraphy were evaluated retrospectively to study usefulness of Ga-scan for early diagnosis of miliary Tbc and evaluation of disease activity. All of ten patients demonstrated significantly diffuse bilateral pulmonary uptakes on 48 hours image. All of three patients of ground-glass pattern in chest roentgemogram also demonstrated increased uptakes. In the statistical analysis, the severity of chest roentgenographic findings showed positive correlation with the activity on Ga?scan. These results suggest that Gallium scan is useful for diagnosis of early miliary tuberculosis and for evaluation of disease activity on follow-up examination of miliary tuberculosis of lung.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.20 no.1
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• pp.66-74
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• 2024

This study investigates the effects of temperatures and strain rates on the strength and ductility of Gr.91 (ASME Grade 91) steel which is widely being used as a heat-resistant material in Generation IV nuclear and super critical thermal power plants. The tensile behavior of modified 9Cr-1Mo (Gr.91) steel was studied for the three strain rates of 6.67×10^-5/s, 6.67×10^-4/s and 6.67×10-3/s over the temperature range from room temperature (RT) to 650℃. Experimental results showed that at specific combinations of temperatures (300~400℃) and strain rates, serrations appeared in the stress-strain curves. Concurrently, abnormal behaviors such as a plateau in yield strength and tensile strength, a minimum in ductility and negative strain rate sensitivity were observed. These phenomena were analyzed as significant characteristics of dynamic strain aging (DSA). Since this abnormal behavior in Gr.91 steel affects the material strength, it is judged that a correlation analysis between DSA and material strength should be crucial in the design and integrity evaluation of Gr. 91 steel pressure vessel and piping subjected to high-temperature loading.

• Food Science of Animal Resources
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• v.41 no.2
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• pp.274-287
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• 2021

The purpose of this study is to examine the physiological characteristics and anti-diabetic effects of Pediococcus pentosaceus KI62. The α-amylase and α-glucosidase inhibitory activity of P. pentosaceus KI62 was 94.86±3.30% and 98.59±0.52%, respectively. In MRS broth containing 3% maltodextrin inoculated by P. pentosaceus KI62, the amounts of short chain fatty acids (SCFA) were propionic acid 18.05±1.85 mg/kg, acetic acid 1.12±0.07 g/100 mL, and butyric acid 2.19±0.061 g/kg, and those of medium chain fatty acids (MCFA) were C8 0.262±0.031 mg/kg, C10 0.279±0.021 mg/kg, and C12 0.203±0.009 mg/kg. Compared to sixteen antibiotics, P. pentosaceus KI62 had the highest sensitivity to penicillin-G and rifampicin, as well as the highest resistance to vancomycin and ampicillin. The strain also showed higher leucine arylamidase and valine arylamidase activities than other enzyme activities, but it did not produce β-glucuronidase which is carcinogenic enzymes. The survival rate of P. pentosaceus KI62 in 0.3% bile was 91.67%. Moreover, the strain showed a 98.63% survival rate in pH 2.0. P. pentosaceus KI62 exhibits resistance to Escherichia coli, Salmonella Typhimurium, Listeria monocytogenes, and Staphylococcus aureus at rates of 29.41%, 38.10%, 51.72%, and 50.47%, respectively. P. pentosaceus (23.31%) showed a similar adhesion ability to L. rhamnosus GG, the positive control (24.49%). These results show that P. pentosaceus KI62 has possibility as a probiotic with anti-diabetic effects.

• Journal of Mushroom
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• v.18 no.3
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• pp.260-267
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• 2020

Phellinus baumii, a white-rot fungus, has been used for centuries as folk medicine in China, Japan, and Korea. This study aimed to evaluate the in vitro anti-diabetic, and anti-cholinesterase, and in vivo anti-inflammatory effects of the fruiting bodies of P. baumii. The methanol (ME) and hot water (HE) extracts (2.0 mg/mL) of P. baumii fruiting bodies suppressed α-amylase activity, exactly 61.33%, and 65.00%, respectively; of note, acarbose, the positive control, inhibited 93.33% of the α-amylase activity. Moreover, the ME and HE (2.0 mg/mL) inhibited 89.67% and 91.00%, respectively, of the activity of α-glucosidase activity, whereas the same concentration of acarbose suppressed 84.67% of the α-glucosidase activity. The ME and HE (1.0 mg/mL) also inhibited 96.05% and 94.58%, respectively, of the acetylcholinesterase (AChE) activity; galanthamine, the positive control, led to an inhibition of 81.12%. The butyrylcholinesterase (BChE) activity was also inhibited by ME and HE (1.0 mg/mL; 91.05% and 82.27%, respectively); of note, the same concentration of galanthamine suppressed 81.12% of the BChE activity. The production of NO in LPS-induced RAW 264.7 macrophages was significantly suppressed by both ME and HE treatments. Importantly, the carrageenan-activated rat hind-paw edema was significantly reduced 2-6 h after ME administration (50 mg/mL). Taken together, the results suggest that the fruiting bodies of P. baumii have α-amylase, α-glucosidase, α-cholinesterase, and anti-inflammatory activities, and, therefore, may be good natural sources for the promotion of human health.

• Journal of Gastric Cancer
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• v.14 no.2
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• pp.67-86
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• 2014

Gastric cancer is one of the most common cancers in the world. Animal models have been used to elucidate the details of the molecular mechanisms of various cancers. However, most inbred strains of mice have resistance to gastric carcinogenesis. Helicobacter infection and carcinogen treatment have been used to establish mouse models that exhibit phenotypes similar to those of human gastric cancer. A large number of transgenic and knockout mouse models of gastric cancer have been developed using genetic engineering. A combination of carcinogens and gene manipulation has been applied to facilitate development of advanced gastric cancer; however, it is rare for mouse models of gastric cancer to show aggressive, metastatic phenotypes required for preclinical studies. Here, we review current mouse models of gastric carcinogenesis and provide our perspectives on future developments in this field.

• 한국생물공학회:학술대회논문집
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• 2003.10a
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• pp.67-67
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• 2003

• 한국신재생에너지학회:학술대회논문집
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• 2011.05a
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• pp.67.1-67.1
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• 2011

Knowledge of the solar radiation components and classified wavelength are essential for modeling many solar energy systems. This is particularly the case for applications that concentrate the incident energy to attain high photo-dynamic efficiency achievable only at the higher intensities. In order to estimate the performance of concentrating solar systems, it is necessary to know the intensity of the beam radiation, as only this components can be concentrated, and The new solar system can generate electricity from ultraviolet and infrared light as well as visible light. The Korea Institute of Energy Research(KIER) has began collecting solar radiation components data since January, 1988, and solar radiation classified wavelength data since November, 2008. KIER's solar radiation components and classified wavelength data will be extensively used by concentrating solar system users or designers as well as by research institutes.

• 한국신재생에너지학회:학술대회논문집
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• 2011.05a
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• pp.67.2-67.2
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• 2011

It is necessary to estimate empirical constants in order to predict the monthly mean daily global radiation on a horizontal surface in the developing areas for alternative energy. Therefore many different equations have proposed to evaluate them for certain areas. In this work a new correlation has been made to predict the solar radiation for any areas over Korea by calculating the regression models taking into account latitude, percentage of possible sunshine, and cloud cover. From the results, the single linear equation proposed by using percentage of possible sunshine method shows reliable results for estimating the global radiation with average annual deviation of -3.1 to +0.6 % from measured values.

• Bulletin of the Korean Space Science Society
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• 2004.04a
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• pp.40-40
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• 2004

The latitude-independent Pc5 pulsations with a spectral peak at -3 mHz were observed with IMAGE and SAMNET magnetometer away, ranging from -47$^{\circ}$ to -77$^{\circ}$geomagnetic latitudes, in the morning sector (0700-1000 local time) during an interval of 30 minutes on April 29, 2001. The spectral amplitude had a local peak at -67$^{\circ}$, where a sudden phase change of -180$^{\circ}$ is found. A vortical equivalent ionospheric current structure centered at latitude between 67$^{\circ}$ and 71$^{\circ}$ was observed during the Pc5 pulsations and the rotational sense of the current vortex was reversed for one cycle of the pulsation. (omitted)