• Title/Summary/Keyword: key evolution

Search Result 689, Processing Time 0.026 seconds

Improvement of Photoheterotrophic $H_2$ production of Rhodobacter sphaeroides by Removing Ammonium Ion Effect Exerted on Nitrogenase (Rhodobacter sphaeroides의 질소고정효소에 미치는 암모니움 이온 효과 제거를 통한 수소생성 증진)

  • Jin, Sang-Hoon;Kim, Mi-Sun;Lee, Jeong-Kug
    • KSBB Journal
    • /
    • v.20 no.6
    • /
    • pp.418-424
    • /
    • 2005
  • Photoheterotrophic evolution of molecular hydrogen by Rhodobacter sphaeroides is mediated by nitrogenase that is regulated transcriptionally and post-translationally by ammonium ion. Two PII-like proteins, GlnB and GlnK, play key roles in mediating inhibition and repression of nitrogenase in the presence of ammonium ion. glnB and glnK of R. sphaeroides were interrupted to abolish the ammonium ion effect controlling nitrogenase. Ammonium ion effect was still observed in mutant having an interruption in either glnB or glnK. However, the nitrogenase activity of glnB-glnK double mutant is not affected by ammonium ion. $H_2$ evolution was improved by increasing gene dosages of nitrogenase-coding genes, nifHDK in trans in glnB-glnK double mutant.

COVID-19 and IT Service: Challenges and Responses (COVID-19와 IT 서비스: 변화와 대응)

  • Lee, Jungwoo;Kang, Ju Young;Lee, Sang Kon
    • Journal of Information Technology Services
    • /
    • v.20 no.5
    • /
    • pp.1-9
    • /
    • 2021
  • Since the first confirmed case in January 2020, Coronavirus disease 2019(COVID-19) has brought many changes to our society, and Korea is no exception. Some changes are direct and immediate such as restrictions on overseas travel and social distancing, but the others are indirect and slowly adapted such as lifestyle changes impacting industries and businesses. IT service sector is tremendously influenced by COVID-19. IT service is used extensively in response to COVID-19 taking advantage of its non-face-to-face characteristics. In that sense, the industry is positively affected and in some sense invigorated, giving birth to new kind of services. This special issue focuses on introducing how the IT services are affected, what kind of transformations are undergoing, and how these are expedited after COVID-19. This special issue expands and extends the case research section by collecting new IT service case studies concerning these topics. After competitive review process, 11 studies are selected for this special issue which deals with four different but closely related aspects: (1) evolutions of private IT services, (2) transformations in public IT services, (3) impacts in the hospitality and tourism industry, and (4) changes of people's behavior along with COVID-19. The first set reports on the evolution of private IT services that have created terms such as foodtech and edutech as we enter a rapid non-face-to-face situation. The second set consists of studies dealing with the evolution of public IT services. Evolution and rapid response to non-face-to-face appear to be no exception in the public sector. The third includes studies of hospitality and tourism which is most strongly affected by COVID-19. The last set deals with the behavioral changes of users such as technostress in telecommuting. Lessons learned through best practices and key problems identified in these studies may help us to actively respond to the coming waves of changes incurred by COVID-19 in our society as well as in the IT service industry.

Rotational instability as a source of asteroidal dust near Earth

  • Jo, Hangbin;Ishiguro, Masateru
    • The Bulletin of The Korean Astronomical Society
    • /
    • v.46 no.1
    • /
    • pp.44.2-45
    • /
    • 2021
  • As implied by the zodiacal light and spacecraft impact measurements, the space between large bodies in our Solar System is filled with interplanetary dust particles (IDPs). IDPs give us deeper insight into the composition and evolution of the Solar System, as well as being a crucial reference for extrasolar research. IDPs can be interpreted as bearers of carbon and organic materials, and thus, their interaction with Earth can be considered as important factors for the birth of terrestrial life. One of the key routes of IDPs entering Earth is via meteoroid streams (Love and Brownlee 1993). The Geminid meteoroid stream is a notable example. Together with its source asteroid (3200) Phaethon, the Phaethon-Geminid stream complex (PGC) (Whipple 1983; Gustafson 1989) can potentially provide information on the properties and evolution of IDPs in near-Earth space. DESTINY+* is a JAXA/ISAS spacecraft planned to launch in 2024 to explore the physical and chemical features of near-Earth IDPs and uncover the dust ejection mechanism of active near-Earth asteroids, especially Phaethon (Arai et al. 2018). Previous studies on the dust ejection mechanism of Phaethon have various degrees of success in explaining the ejection of submillimeter particles and try to recreate the dust replenishment rate of the Geminid stream. However, none of them are satisfactory for explaining the observed Geminid stream, especially for larger particles of a millimeter and centimeter scales. Inspired by the discovery of rotational mass shedding in the Main Belt region (Jewitt et al., 2014), we investigate a dust ejection scenario by rotational instability on Phaethon. Using the N-body integrator MERCURY6 (Chambers 1999; modified by Jeong 2014), we performed a long-term integration of dust particles of various sizes ejected at ~1 m/s. Through this process, we discuss the implications Phaethon's rotation may have on its ejection, the formation and evolution of IDP by this mechanism, and contribute to the DESTINY+ mission.

  • PDF

Microstructure evolution and effect on deuterium retention in oxide dispersion strengthened tungsten during He+ irradiation

  • Ding, Xiao-Yu;Xu, Qiu;Zhu, Xiao-yong;Luo, Lai-Ma;Huang, Jian-Jun;Yu, Bin;Gao, Xiang;Li, Jian-Gang;Wu, Yu-Cheng
    • Nuclear Engineering and Technology
    • /
    • v.52 no.12
    • /
    • pp.2860-2866
    • /
    • 2020
  • Oxide dispersion-strengthened materials W-1wt%Pr2O3 and W-1wt%La2O3 were synthesized by wet chemical method and spark plasma sintering. The field emission scanning electron microscopy (FE-SEM) analysis, XRD and Vickers microhardness measurements were conducted to characterize the samples. The irradiations were carried out with a 5 keV helium ion beam to fluences up to 5.0 × 1021 ions/m2 under 600 ℃ using the low-energy ion irradiation system. Transmission electron microscopy (TEM) study was performed to investigate the microstructural evolution in W-1wt%Pr2O3 and W-1wt%La2O3. At 1.0 × 1020 He+/m2, the average loops size of the W-1wt%Pr2O3 was 4.3 nm, much lower than W-1wt% La2O3 of 8.5 nm. However, helium bubbles were not observed throughout in both doped W materials. The effects of pre-irradiation with 1.0 × 1021 He+/m2 on trapping of injected deuterium in doped W was studied by thermal desorption spectrometry (TDS) technique using quadrupole mass spectrometer. Compared with the samples without He+ pre-irradiation, deuterium (D) retention of doped W materials increased after He+ irradiation, whose retention was unsaturated at the damage level of 1.0 × 1022D2+/m2. The present results implied that irradiation effect of He+ ions must be taken into account to evaluate the deuterium retention in fusion material applications.

Transcript Profiling of Toll-Like Receptor mRNAs in Selected Tissues of Mink (Neovison vison)

  • Tong, Mingwei;Yi, Li;Cheng, Yuening;Zhang, Miao;Cao, Zhigang;Wang, Jianke;Zhao, Hang;Lin, Peng;Yang, Yong;Cheng, Shipeng
    • Journal of Microbiology and Biotechnology
    • /
    • v.26 no.12
    • /
    • pp.2214-2223
    • /
    • 2016
  • Toll-like receptors (TLRs) can recognize conserved molecular patterns and initiate a wide range of innate and adaptive immune responses against invading infectious agents. The aim of this study was to assess the transcript profile of mink TLRs (mTLRs) in mink peripheral blood mononuclear cells (PBMCs) and a range of tissues, and to explore the potential role of mTLRs in the antiviral immune response process. The results indicated that the mTLR partial nucleotide sequences had a high degree of nucleotide identity with ferret sequences (95-98%). Phylogenetic analysis showed that mammalian TLRs grouped into five TLR families, with a closer relationship of the mTLRs with those of ferret than the other mammalian sequences. Moreover, all the mTLRs were ubiquitously expressed in lymphoid organs (spleen and lymph nodes) and PBMCs. Interestingly, the mTLR expression patterns in lung, uterus, and heart showed quite a lot of similarity. Another remarkable observation was the wide expression of mTLR1-3 mRNAs in all tissues. Among the analyzed tissues, skeletal muscle was revealed to being the lowest repertoire of mTLR expression. Additionally, mink PBMCs exposed to the canine distemper virus revealed significant upregulation of mTLR2, mTLR4, mTLR7, and mTLR8 mRNAs, indicating that mTLRs have a role in innate immunity in the mink. Collectively, our results are the first to establish the basic expression patterns of mTLRs and the relationship between mTLRs and a virus, which will contribute to better understanding of the evolution and the functions of mTLRs in the innate immune system in minks.

Design of cellular, satellite, and integrated systems for 5G and beyond

  • Kim, Junhyeong;Casati, Guido;Cassiau, Nicolas;Pietrabissa, Antonio;Giuseppi, Alessandro;Yan, Dong;Strinati, Emilio Calvanese;Thary, Marjorie;He, Danping;Guan, Ke;Chung, Heesang;Kim, Ilgyu
    • ETRI Journal
    • /
    • v.42 no.5
    • /
    • pp.669-685
    • /
    • 2020
  • 5G AgiLe and fLexible integration of SaTellite And cellulaR (5G-ALLSTAR) is a Korea-Europe (KR-EU) collaborative project for developing multi-connectivity (MC) technologies that integrate cellular and satellite networks to provide seamless, reliable, and ubiquitous broadband communication services and improve service continuity for 5G and beyond. The main scope of this project entails the prototype development of a millimeter-wave 5G New Radio (NR)-based cellular system, an investigation of the feasibility of an NR-based satellite system and its integration with cellular systems, and a study of spectrum sharing and interference management techniques for MC. This article reviews recent research activities and presents preliminary results and a plan for the proof of concept (PoC) of three representative use cases (UCs) and one joint KR-EU UC. The feasibility of each UC and superiority of the developed technologies will be validated with key performance indicators using corresponding PoC platforms. The final achievements of the project are expected to eventually contribute to the technical evolution of 5G, which will pave the road for next-generation communications.

Experimental investigation of the mechanical behaviors of grouted crushed coal rocks under uniaxial compression

  • Jin, Yuhao;Han, Lijun;Meng, Qingbin;Ma, Dan;Wen, Shengyong;Wang, Shuai
    • Geomechanics and Engineering
    • /
    • v.16 no.3
    • /
    • pp.273-284
    • /
    • 2018
  • A detailed understanding of the mechanical behaviors for crushed coal rocks after grouting is a key for construction in the broken zones of mining engineering. In this research, experiments of grouting into the crushed coal rock using independently developed test equipment for solving the problem of sampling of crushed coal rocks have been carried out. The application of uniaxial compression was used to approximately simulate the ground stress in real engineering. In combination with the analysis of crack evolution and failure modes for the grouted specimens, the influences of different crushed degrees of coal rock (CDCR) and solidified grout strength (SGS) on the mechanical behavior of grouted specimens under uniaxial compression were investigated. The research demonstrated that first, the UCS of grouted specimens decreased with the decrease in the CDCR at constant SGS (except for the SGS of 12.3 MPa). However, the UCS of grouted specimens for constant CDCR increased when the SGS increased; optimum solidification strengths for grouts between 19.3 and 23.0 MPa were obtained. The elastic moduli of the grouted specimens with different CDCR generally increased with increasing SGS, and the peak axial strain showed a slightly nonlinear decrease with increasing SGS. The supporting effect of the skeleton structure produced by the solidified grouts was increasingly obvious with increasing CDCR and SGS. The possible evolution of internal cracks for the grouted specimens was classified into three stages: (1) cracks initiating along the interfaces between the coal blocks and solidified grouts; (2) cracks initiating and propagating in coal blocks; and (3) cracks continually propagating successively in the interfaces, the coal blocks, and the solidified grouts near the coal blocks. Finally, after the propagation and coalescence of internal cracks through the entire specimens, there were two main failure modes for the failed grouted specimens. These modes included the inclined shear failure occurring in the more crushed coal rock and the splitting failure occurring in the less crushed coal rock. Both modes were different from the single failure mode along the fissure for the fractured coal rock after grouting solidification. However, compared to the brittle failure of intact coal rock, grouting into the different crushed degree coal rocks resulted in ductile deformation after the peak strength for the grouted specimens was attained.

Listeria monocytogenes Serovar 4a is a Possible Evolutionary Intermediate Between L. monocytogenes Serovars 1/2a and 4b and L. innocua

  • Chen, Jianshun;Jiang, Lingli;Chen, Xueyan;Luo, Xiaokai;Chen, Yang;Yu, Ying;Tian, Guoming;Liu, Dongyou;Fang, Weihuan
    • Journal of Microbiology and Biotechnology
    • /
    • v.19 no.3
    • /
    • pp.238-249
    • /
    • 2009
  • The genus Listeria consists of six closely related species and forms three phylogenetic groups: L. monocytogenes-L. innocua, L. ivanovii-L. seeligeri-L. welshimeri, and L. grayi. In this report, we attempted to examine the evolutionary relationship in the L. monocytogenes-L. innocua group by probing the nucleotide sequences of 23S rRNA and 16S rRNA, and the gene clusters lmo0029-lmo0042, ascB-dapE, rplS-infC, and prs-ldh in L. monocytogenes serovars 1/2a, 4a, and 4b, and L. innocua. Additionally, we assessed the status of L. monocytogenes-specific inlA and inlB genes and 10 L. innocua-specific genes in these species/serovars, together with phenotypic characterization by using in vivo and in vitro procedures. The results indicate that L. monocytogenes serovar 4a strains are genetically similar to L. innocua in the lmo0035-lmo0042, ascB-dapE, and rplS-infC regions and also possess L. innocua-specific genes lin0372 and lin1073. Furthermore, both L. monocytogenes serovar 4a and L. innocua exhibit impaired intercellular spread ability and negligible pathogenicity in mouse model. On the other hand, despite resembling L. monocytogenes serovars 1/2a and 4b in having a nearly identical virulence gene cluster, and inlA and inlB genes, these serovar 4a strains differ from serovars 1/2a and 4b by harboring notably altered actA and plcB genes, displaying strong phospholipase activity and subdued in vivo and in vitro virulence. Thus, by possessing many genes common to L. monocytogenes serovars 1/2a and 4b, and sharing many similar gene deletions with L. innocua, L. monocytogenes serovar 4a represents a possible evolutionary intermediate between L. monocytogenes serovars 1/2a and 4b and L. innocua.

Theoretical prediction on thickness distribution of cement paste among neighboring aggregates in concrete

  • Chen, Huisu;Sluys, Lambertus Johannes;Stroeven, Piet;Sun, Wei
    • Computers and Concrete
    • /
    • v.8 no.2
    • /
    • pp.163-176
    • /
    • 2011
  • By virtue of chord-length density function from the field of statistical physics, this paper introduced a quantitative approach to estimate the distribution of cement paste thickness between aggregates in concrete. Dynamics mixing method based on molecular dynamics was employed to generate one model structure, then image analysis algorithm was used to obtain the distribution of thickness of cement paste in model structure for the purpose of verification. By comparison of probability density curves and cumulative probability curves of the cement paste thickness among neighboring aggregates, it is found that the theoretical results are consistent with the simulation. Furthermore, for the model mortar and concrete mixtures with practical volume fraction of Fuller-type aggregate, this analytical formula was employed to predict the influence of aggregate volume fraction and aggregate fineness. And evolution of its mean values were also investigated with the variation of volume fraction of aggregate as well as the fineness of aggregates in model mortars and concretes.

An Efficient Broadcast Authentication Scheme with Batch Verification for ADS-B Messages

  • Yang, Haomiao;Kim, Hyunsung;Li, Hongwei;Yoon, Eunjun;Wang, Xiaofen;Ding, Xuefeng
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • v.7 no.10
    • /
    • pp.2544-2560
    • /
    • 2013
  • As a cornerstone of the next generation air traffic management (ATM), automatic dependent surveillance-broadcast (ADS-B) system can provide continual broadcast of aircraft position, identity, velocity and other messages over unencrypted data links to generate a common situational awareness picture for ATM. However, since ADS-B messages are unauthenticated, it is easy to insert fake aircrafts into the system via spoofing or insertion of false messages. Unfortunately, the authentication for ADS-B messages has not yet been well studied. In this paper, we propose an efficient broadcast authentication scheme with batch verification for ADS-B messages which employs an identity-based signature (IBS). Security analysis indicates that our scheme can achieve integrity and authenticity of ADS-B messages, batch verification, and resilience to key leakage. Performance evaluation demonstrates that our scheme is computationally efficient for the typical avionics devices with limited resources, and it has low communication overhead well suitable for low-bandwidth ADS-B data link.