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Comparative Study on the Pulse Wave Variables and Sasang Constitution in Diabetes Mellitus Patients and Healthy Subjects (당뇨병 환자와 건강인의 맥상과 사상체질에 관한 연구)

  • Park, Su-Jeong;Kim, Kyung-Yo;Lee, Si-Woo;Kwon, Young-Mi;Kil, Eun-Young;Joo, Jong-Cheon
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.6
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    • pp.1601-1610
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    • 2007
  • The purpose of this study was to determine whether a pulse analyzer was useful 1) to characterize the variables of pulse wave of diabetes mellitus group, compared with those of healthy subjects, and 2) to determine Sasang Constitution in diabetes mellitus group and healthy subjects. 1. The sum of pulse pressure (energy) and the ratio of systolic period area (As%), called pulse pressure-related variables, were higher in diabetes mellitus group than healthy group, while the height of dicrotic wave (h5) and the ratio of height of dicrotic wave to height of percussion wave (h5/h1), correlated with arterial compliance, were lower in diabetes mellitus group than healthy group. 2. Taeumin of diabetes mellitus group showed higher pressure-related variables than that of healthy group. 3. Soumin of diabetes mellitus group had shorter the time to dicrotic wave (t5) than that of healthy group. 4. Soyangin of diabetes mellitus group showed higher heart rates and lower values in pulse wave time-related variables, including time to dicrotic wave(t5), time to incisura (t4), total time minus time to incisura (t-t4), total time (t), width of percussion wave (w), and the ratio of width of percussion wave to total time (w/t), than that of healthy group. 5. Contact pressure (CP), sum of pulse pressure (energy), height of pre-incisura (h2), height of incisura (h4), width of percussion wave (w), time to incisura (t4), time to percussion wave (t1), variance of total time (Vt), variance of height of percussion wave(Vp) and the ratio of height of incisura to height of percussion wave (h4/h1) were used to develop the rules of Sasang Constitution Classification with about seventy five percents accuracy. These suggested that the pulse analyzer was useful to evaluate the risk degree of diabetes mellitus and to determine Sasang Constitution among either diabetes mellitus group or healthy group.

Solving Probability Constraint in Robust Optimization by Minimizing Percent Defective (불량률 최소화를 통한 강건 최적화의 확률제한조건 처리)

  • Lee, Kwang Ki;Park, Chan Kyoung;Kim, Geun Yeon;Lee, Kwon Hee;Han, Sang Wook;Han, Seung Ho
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.37 no.8
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    • pp.975-981
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    • 2013
  • A robust optimization is only one of the ways to minimize the effects of variances in design variables on the objective functions at the preliminary design stage. To predict the variances and to formulate the probabilistic constraints are the most important procedures for the robust optimization formulation. Though several methods such as the process capability index and the six sigma technique were proposed for the prediction and formulation of the variances and probabilistic constraints, respectively, there are few attempts using a percent defective which has been widely applied in the quality control of the manufacturing process for probabilistic constraints. In this study, the robust optimization for a lower control arm of automobile vehicle was carried out, in which the design space showing the mean and variance sensitivity of weight and stress was explored before robust optimization for a lower control arm. The 2nd order Taylor expansion for calculating the standard deviation was used to improve the numerical accuracy for predicting the variances. Simplex algorithm which does not use the gradient information in optimization was used to convert constrained optimization into unconstrained one in robust optimization.

Robust Optimization of the Solenoid Assembly in Electromagnetic Limited Slip Differential by Considering the Uncertainties in Machining Variables (가공변수의 불확실성을 고려한 전자제어식 차동제한장치 솔레노이드 어셈블리의 강건 최적설계)

  • Oh, Sang-Kyun;Lee, Kwang-Ki;Suh, Chang-Hee;Jung, Yun-Chul;Kim, Young-Suk
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.35 no.10
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    • pp.1307-1313
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    • 2011
  • The mechanical limited slip differential (LSD) in vehicles is being replaced by the electromagnetic LSD because of its fast response and better active control characteristics. The coil housing made of STS 304 is one of the most important parts in the solenoid assembly of the electromagnetic LSD. High geometrical accuracy is a prerequisite for the manufacture of such coil housings, but precision machining is difficult because of the use of STS 304 thin plate and the variance in machining variables. The aim of this study is to optimize the mean and variance of the shape accuracy in the coil housing by finding a robust solution for the machining process conditions. The mean and standard deviation of the jaw contact pressure, cutting speed, and feed rate are considered to be the major parameters for minimizing the geometrical mean and variance. The response surface model based on the second-order Taylor series is combined together to minimize the mean and variance of the shape accuracy of the coil housing.

Molecular Taxonomy based on 16S rDNA Analysis and Pathogenicity of Yersinia pseudotuberculosis Isolated from Spring Waters (약수에서 분리한 Yersinia pseudotuberculosis의 병원성과 16S rDNA 분석에 의한 분자학적 분류)

  • Lee, Young-Kee;Choi, Sung-Min;Oh, Soo-Kyung;Lee, Kang-Moon;Ryeom, Kon
    • Korean Journal of Microbiology
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    • v.37 no.1
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    • pp.9-14
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    • 2001
  • In order to investigate the pathogenicity and development of differential identification technique in the Yersinia species and other entericbacteria, we isolated 5 strains of Y.pseudotuberculosis from spring water sites in Seoul. The biochemical characteristics of isolated strains revealed that indole, VP($25^{\circ}C$, $37^{\circ}C$), $H_2S$, phenylalanine, lysine, arginine, ornithine, gas from glucose, lactose, sucrose, sorbitol, oxidase and motility($37^{\circ}C$) were all negative and urease, glucose, mannitol, salicin, catalase and motility($25^{\circ}C$) were all positive. To detect the causative agent of pseudotuberculosis(Y.pseudotuberculosis), we carried out a study using a PCR with inv primers complementary to the pathogenic region and found that all strains were positive, this revealed that strains from spring waters were pathogenic. Also 16S rDNA for total 5 strains of Y. pseudotuberculosis were amplified and a stretch of approximately 1,450 nucleotides were sequenced and analyzed. The 16S rDNA nucleotide sequence homologies among Yersinia species ranged 97.5% to 100% and between Y.pseudotuberculosis and other entericbacteria they ranged 93.0% to 95.1%. The Phylogenetic tree generated from the sequence analysis of the 16S rDNA gene showed 3 coherent clusters that could be separated into Y.pseudotuberculsis strains, some Yersinia species strains and other entericbacteria strains.

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강지진동 분석의 최적화를 위한 고려요소

  • 이석태;조봉곤;이정모;조영삼
    • Proceedings of the International Union of Geodesy And Geophysics Korea Journal of Geophysical Research Conference
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    • 2003.05a
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    • pp.17-17
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    • 2003
  • 한반도에 있어서의 지진의 영향을 분석하기 위해서는 강지진동 연구가 필수적이다. 강지진동 자료가 부족한 한반도의 특성상 모사를 통해 연구하고 있다. 강지진동 분석을 하기 위해서는 되도록 노이즈가 포함되어 있지 않은 지진파자료를 선택하여 그 지진자료의 스펙트럼 분석을 통해 감쇠상수 k, Q 등을 구한다. 이러한 감쇠상수 값을 통해 한반도의 진동 특성을 이해할 수 있다. 그러나 감쇠상수를 구하는 과정에서 감쇠상수 분석에 사용된 지진자료에 노이즈가 더해졌을 경우, 어떤 형태로 스펙트럼 영역에 영향을 미치고, 감쇠상수에는 어떤 영향을 미치는 지를 연구하여 노이즈효과를 제거할 수 있는 최적화된 분석에 관한 연구가 선행되어야 한다고 본다. 따라서 이번 연구에서는 강지진동 모사프로그램을 가지고 노이즈효과를 적용하면서 감쇠상수에 노이즈가 어떤 영향을 미치는 지에 대한 수치 해석적 연구를 실시하였다. 합성지진파에 이 합성지진파와 전혀 다른 주파수 형태를 보이는 노이즈를 강도를 달리하면서 합성해 본 결과, 노이즈효과를 고려할 수 있는 몇 가지 요소가 있음을 알 수 있었다. 감쇠상수 k값을 강지진동 모사프로그램으로부터 값을 달리하며 합성해 본 결과 노이즈효과를 보이는 것을 알 수 있었으며, 감쇠상수 k를 선형회귀를 통해 $k_{s}$$k_{q}$를 구할 때의 적용 주파수 범위를 변화시켰을 때도 일정한 양상의 노이즈 효과를 보였다. 또 지진자료와 노이즈를 중첩시킨 지진파 시계열 자료의 정부분만을 감쇠상수 k를 구하는 선형회귀에 이용했을 경우에도 노이즈 효과를 보였다. 또한 계산되어 나온 감쇠상수 값으로부터 특정지역의 지반운동의 특성을 이해할 수 있는 스펙트럼 가속도, 최대 가속도, 및 최대속도 값에 따른 감쇠식을 구하였다. 이것을 한반도와 같은 판 내부 환경인 ENA 값과 비교하였으며 기존의 연구와도 비교하였다.심으로부터 지오이드까지의 거리, 지오이드로부터 지표까지의 거리를 정의해주었으며, 각 격자점의 수직구조를 정의하기 위해 깊이에 따른 각 매질의 밀도, P파의 속도, S파의 속도, P파에 대한 Q값, S파에 대한 Q값을 정의 해주었다. S파의 속도를 구하기 위해서 지구 내부 물질을 포아송 매질이라는 가정 하에, 관계식을 $Vp{\;}={\;}SQRT(3){\;}{\times}{\;}Vs$ 이용하였다. 획득한 모델치들을 이용해 동해와 동해 인근 지역에 대한 초기모델을 구축하였다. 약 1 × 10/sup 6/ e/sup -//sec·n㎡ 의 전자선량에 해당되며 이를 기준으로 각각의 illumination angle에 대한 임계전자선량을 평가할 수 있었다. 실질적으로 Cibbsite와 같은 무기수화물의 직접가열실험 시 전자빔 조사에 의해 야기되는 상전이 영향을 배제하고 실험을 수행하려면 illumination angle 0.2mrad (Dose rate : 8000 e/sup -//sec·n㎡)이하로 관찰하고 기록되어야 함을 본 자료로부터 알 수 있었다.운동횟수에 의한 영향으로써 운동시간을 1일 6시간으로 설정하여, 운동횟수를 결정하기 위하여 오전, 오후에 각 3시간씩 운동시키는 방법과 오전부터 6시간동안 운동시키는 두 방법을 이용하여 품질을 비교하였다. 각 조건에 따라 운동시킨 참돔의 수분함량을 나타낸 것으로, 2회(오전 3시간, 오후 3시간)에 나누어서 운동시키기 위한 육의 수분함량은 73.37±2.02%를 나타냈으며, 1회(6시간 운동)운동시키기 위한 육은 71.74±1.66%을 나타내었다. 각각의 운동조건에서 양식된 참돔은 사육초기에는 큰 변화가 없었으나, 사육 5일 이후에는 수분함량이 증가하여 15일에는 76.40±0.14, 75.62±0.98%의 수분함량을 2회와 1회 운동시킨 참돔의 육에서 각각 나타났다. 운동횟수에 따른 지

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Simulation of Separation Properties of Propylene/propane in Silver Nanoparticle Containing Facilitated Transport Membrane (전산모사 프로그램을 이용한 은나노함유 촉진수송막의 프로필렌/프로판 분리특성 예측)

  • Park, Chae Young;Han, Sang Hoon;Kim, Jeong Hoon;Lee, Yongtaek
    • Membrane Journal
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    • v.24 no.5
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    • pp.409-415
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    • 2014
  • This study is aimed to separate propylene and propane using membrane process instead of NCC(Naphtha Cracking Center) $C_3$ splitter. Membrane process is a low energy consumption and eco-friendly process while $C_3$ splitter requires high energy consumption in petrochemical processes. In this study, high performance facilitated transport membrane (FTM) is used for propylene/propane separation. FTM module was prepared on top of porous polyetherimide hollow fiber using PVP/$AgBF_4$/TCNQ. We developed simulation program predicting the membrane separation properties under operation conditions. Separation properties of FTM module for propylene and propane were obtained from the simulation program based on the pure gas permeation data. Based on these results, it is predicted that an one-stage membrane process provides 99.5% of propylene at permeate side from a binary gas mixture of 95/5 vol% $C_3H_6$ / vol% $C_3H_8$ supplied as a feed gas.

A Study on the Unmanned convenience Store Operation System from the Viewpoint of Visual Merchandising (비주얼 머천다이징 관점에서의 무인 편의점 운영시스템에 관한 연구)

  • Seo, Jung-Hwa;Yang, Hoe-Chang;Park, Chul-Ju;Youn, Myoung-Kil
    • The Journal of Industrial Distribution & Business
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    • v.9 no.12
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    • pp.45-53
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    • 2018
  • Purpose - The purpose of the study was to investigate operation system of current convenience store and competing retail store and to find out development of unattended convenience store. Operators can save labor cost and solve labor seeking when opening shop under suitable environment and commerce area, and assure of employee's safety. Customers are allowed to select commodity comfortably without disclosure of face and to shorten standby time at simple store opening, buying and paying and to produce convenient living environment by financing, delivery and goods control. This study examined effect and problems of operation of existing and unattended convenience store from point of view of visual merchandising to find out model of unattended convenience store and to strengthen competitiveness of convenience store business. Research design, data, and methodology - Research procedure of accomplishment of goal of the study was: The study investigated state of distribution business, and role and definition of VMD. First, VMD played an important role of promotion and competitiveness of unattended convenience stores. Second, the author investigated research and cases of unattended convenience stores 14 months, that is to say, from August 15, 2017 to October 15, 2018. Third, the author investigated on-the-spot three of common convenience stores, three of unattended convenience stores and three of retailers one month, that is to say, June 1, 2018 to July 1, 2018. The subject was convenience stores and retailers selling similar type of products at Seoul and metropolitan area. Results - Layout, selling place, brand identity, goods assortment, authentication system, product information cognition and control, buying and payment system, security system, salesmen, promotion and other services should be improved from point of view of merchandising. Structure, furniture, lighting, voice, façade, VP, PP, IP and POP should be developed. Conclusions - Unattended convenience stores saved operating cost and lessened labor and gave visitors convenience and comfortable shopping and made use of resources effectively. Further studies with quantitative analysis shall find out strategic conditions for promotion of unattended convenience stores.

RADIOPACITY OF CAD/CAM CERAMICS (CAD/CAM용 도재의 방사선 불투과성에 관한 연구)

  • Lee, Jong-Hyeok;Choi, Han-Seuk;Um, Chung-Moon
    • Restorative Dentistry and Endodontics
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    • v.23 no.1
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    • pp.357-365
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    • 1998
  • 목적: 치과용 수복재료의 방사선 불투과성은 매우 다양하다. 따라서 다양한 수복재료의 방사선 불투과성을 인지하여 치질과 비교하면 이차우식의 진단에 도움이 될 수 있다. 도재의 방사선 불투과성에 따라 적절한 luting cement의 선택이 가농해진다. 수복재료의 방사선 불투과성은 알루미늄 step wedge 의 후경과 방사선 불투과성과의 상관관계 의해 측정된다. 본 연구의 목적은 CAD/CAM용 도재와 이틀의 접착에 쓰이는 접착재료의 방사선 불투과성을 조사해 적절한 재료의 선택과 이차우식 진단의 효율결정에 도움이 되게 하는데 있다. 방법: 본 실험에서는 CAD/CAM용 도재인 Vita MarkII, Dicor MGC와 이의 접착에 사용되는 Z-100, 그리고 luting cement인 Duo cement, Scotchbond resin cement를 사용해 방사선 불투과성을 측정하였다. 시편 제작을 위해 도재를 저속절단기로 두께 2mm, 3mm로 절단하였으며 Z-100과 cement시편은 두께 2mm와 3mm, 직경 7.0mm의 금속 주형을 제작한 후 재료를 양쪽 면에 유리판을 대고 조임쇠로 압접하였으며 광조사기를 사용하여 각 재료마다 두 가지 두께로 10개씩 100개의 시편을 제작하였다. 치질의 시편을 얻기 위해 교정 목적으로 최근에 발거된 정상적인 상악 소구치를 저속 절단기를 사용하여 협설측 교두정을 기준 삼아 2mm, 3mm 두께로 절단하였으며 방사선 불투과성의 기준을 위해 12개의 step으로 구성된 12mm두께의 aluminum step wedge를 사용하였다. Kodak E-Speed occlusal film에 aluminum step wedge와 시편들을 위치시킨 후 70kVp, 7mA, 2.16mm aluminum filtration으로 고정된 dental X-ray unit을 사용하여 target과 film 사이의 거리는 25cm, 노출시간은 0.2초로 하여 방사선 촬영을 한 다음, 현상된 방사선 사진상에 나타난 방사선 불투과성을 X-rite 301 densitometer를 이용하여 측정한 값들의 평균을 냈다. 얻어진 결과는 one-way ANOVA Duncan test(P<0.01)로 검증하였다. 결론: 1. Dicor MGC의 방사선 불투과성은 법랑질보다 약간 높게 나타났다.(P<0.01) 2. Vita Mark Il는 상아질보다 낮은 방사선 불투과성을 보였다.(P<0.01) 3. Z-100과 Luting cement들의 방사선 불투과성은 법랑질보다 높았다. Duo cement가 방사선 불투과성이 가장 높았고 그 다음이 Z-100, 그리고 Scotchbond resin cement 순이었다. 4. Z-100과 2종류의 방사선 불투과성 luting cement들은 Vita Mark II 와 같이 사용하면 2차우식 진단에 도움이 된다.

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Development of Shielding using Medical Radiological Contrast Media; Comparison Analysis of Barium Sulfate Iodine Shielding ability by Monte Carlo Simulation (의료방사선 조영제를 이용한 차폐체 개발; 몬테카를로 시뮬레이션을 통한 황산바륨과 요오드의 차폐능 비교분석)

  • Kim, Seon-Chil
    • Journal of the Korean Society of Radiology
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    • v.11 no.5
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    • pp.329-334
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    • 2017
  • The purpose of this study is to estimating the possibility of manufacturing radiation shielding sheet by searching for environmentally friendly materials suitable for medical environment of medical radiation shielding. There are many tungsten products which are currently used as shielding materials in place of lead, but there are small problems in the mass production of lightweight shielding sheets due to economical efficiency. To solve these problems, a lightweight, environmentally friendly material with economical efficiency is required. In this study, Barium sulphate and Iodine were proposed. Both materials are already used as contrast medias in radiography, and it is predicted that the shielding effect will be sufficient in a certain region as a shielding material because of the characteristic of absorbing radiation. Therefore, in this study, we used a Monte Carlo simulation to simulate radiation shielding materials. When it is a contrast agent such as Barium sulfate and Iodine, the radiation absorption effect in the high energy region appears greatly, and the effectiveness of the two shielding substance in the energy region of the star with thickness of 120 kVp is also evaluated in the medical radiation imaging region. Simulated estimation results it was possible to estimate the effectiveness of shielding for all two substances. Iodine has higher shielding effect than barium sulfate, 0.05 mm thick appears great effect. Therefore, the Monte Carlo simulation confirms that iodine, which is a radiological contrast agent, is also usable as barium sulfate in the production of radiation shielding sheets.

Distribution of Rotavirus G Serotypes in ChungJu Area (충주 지역 설사 환아의 Rotavirus G Serotype 분포에 관한 연구)

  • Sim, Jae-Geon;Kwon, Jae-Bong;Kang, Shien-Young
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.3 no.1
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    • pp.41-46
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    • 2000
  • Purpose: It is important to have the epidemiologic data of rotavirus serotypes for the application of polyvalent rotavirus vaccines. Epidemiological studies of rotavirus serotypes in Korea have been reported only in limited areas with small number of cases. Authors tried to investigate the distribution of rotavirus G serotypes in ChungJu area with RT-PCR. Method: Stool specimens were collected from 202 children with acute diarrheal symptoms, who admitted to or visited Kon-Kuk University Hospital in ChungJu from June 1998 to May 1999. Samples were screened for rotavirus with EIA method (TestPack Rotavirus, Abbott Laboratories) and rotavirus G Serotypes were determined by RT-PCR. Results: Rotavirus was positive in 46.6%. The incidence of G serotypes was as follows; G1 10%, G2 10%, G3 28%, G4 26%, and G9 20%. There were three cases of multiple serotypes; G1 with G9, G2 with G9, and G4 with G9. Serotype of G8 was not found. Conclusion: The proportion of G serotypes in ChungJu is much different from previous reports. Serotype of G9 was found which had not been reported in Korean children till now. Long term plans for the investigation of rotavirus serotypes must be needed in wide area.

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