• The Korean Journal of Nuclear Medicine Technology
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• v.18 no.1
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• pp.10-18
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• 2014

Purpose: Among different PET/CT devices which are composed of same PET model but different CT models, SUV, usually used for quantitative evaluation, was measured to assess the accuracy of follow up scans in different PET/CT and confirm that interequipment compatibility is useful in arranging the PET/CT exam appointment. Materials and Methods: Using ACR PET Phantom, PET NEMA IEC Body Phantom, SNM Chest Phantom and Ge-68 cylinder Phantom, $SUV_{mean}$ and $SUV_{max}$ was measured by 3 different models of PET/CT (Discovery 690, Discovery 690Elite and Discovery 710, GE) made in same company. ANOVA was used to evaluate the significant difference in the result. Results: In the result, the average of $SUV_{max}$ was D690 (25 mm-1.82, 16 mm-1.75, 12 mm-1.73, 8 mm-1.44), D690E (25 mm-1.76, 16 mm-1.92, 12 mm-1.78, 8 mm-1.55) and D710 (25 mm-1.84, 16 mm-1.89, 12 mm-1.77, 8 mm-1.61) in ACR Phantom, D690 (25 mm-2.26, 16 mm-2.25, 12 mm-1.92, 8 mm-1.85), D690E (25 mm-2.45, 16 mm-2.25, 12 mm-2.05 8 mm-1.91) and D710(25 mm-2.49, 16 mm-2.20, 1 2mm-2.30, 8 mm-2.05) in PET NEMA IEC Body Phantom, D690-1.04, D690E-1.10 and D710-1.09 in SNM Chest Phantom and D690-0.81, D690E-0.81, D710-0.84 in Ge-68 cylinder Phantom. The differences between average SUV of 4 phantoms were $SUV_{mean}$-1.87%, $SUV_{max}$-2.15%. And also as a result of ANOVA analysis, there was no significant difference statistically. Conclusion: If different models of PET/CT have same specification of PET system, there was no significant difference in $SUV_{mean}$ and $SUV_{max}$ even though they have different CT system. And also differences of $SUV_{mean}$ and $SUV_{max}$ in phantom images were under 5% which many manufacturers recommend. Therefore, follow up scan will be possible using different PET/CT if it has same specification of PET system with the previous PET/CT. This information will enable the accurate comparative analysis when conducting follow up scans and be helpful to schedule PET/CT exam more effectively.

• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.2
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• pp.33-37
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• 2010

Purpose: In the early stage of using PET/CT, it was used to damper revision but recently shows that CT with MDCT is commonly used and works well for an anatomical diagnosis. This hospital makes the accuracy and convenience more higher in the diagnosis and evaluate of coronary heart disease through concurrently running myocardial perfusion SPECT examination, myocardial PET examination with FDG, and CT coronary artery CT angiography(coronary CTA) used PET/CT with 64-slice. This report shows protocol and image based on results from about 400 coronary heart disease examinations since having 64 channels PET/CT in July 2007. Materials and Methods: An Equipment for this examination is 64-slice CT and Discovery VCT (DVCT) that is consisted of PET with BGO ($Bi_4Ge_3O_{12}$) scintillation crystal by GE health care. First myocardial perfusion SPECT with pharmacologic stress test to reduce waiting time of a patient and get a quick diagnosis and evaluation, and right after it, myocardial FDG PET examination and coronary CTA run without a break. One-stop evaluation protocol of ischemic heart disease is as follows. 1)Myocardial perfusion SPECT with pharmacologic stress: A patient is injected with $^{99m}Tc$-MIBI 10 mCi and does not have any fatty food for myocardial PET examination and drink natural water with ursodeoxcholic acid 100 mg and we get SPECT image in an hour. 2)Myocardial FDG PET: To reduce blood fatty content and to increase uptake of FDG, we used creative oral glucose load using insulin and Acipimox to according to blood acid content. A patient is injected with $^{18}F$-FDG 5 mCi for reduction of his radiation exposure and we get a gated image an hour later and get delay image when we need. 3) Coronary CTA: The most important point is to control heart rate and to get cooperation of patient's breath. In order to reduce a heart rate of him or her below 65 beats, let him or her take beta blocker 50 mg ~ 200 mg after a consultation with a doctor about it and have breath-practices then have the examination. Right before the examination, we spray isosorbide dinitrate 3 to 5 times to lower tension of bessel wall and to extension a blood wall of a patient. It makes to get better the shape of an anatomy. At filming, a patient is injected CT contrast with high pressure and have enough practices before the examination in order to have no problem. For reduction of his radiation exposure, we have to do ECG-triggered X-ray tube modulation exposure. Results: We evaluate coronary artery stenosis through coronary CTA and study correlation (culprit vessel check) of a decline between stenosis and perfusion from the myocardial perfusion SPECT with pharmacologic stress, coronary CTA, and can check viability of infarction or hibernating myocardium by FDG PET. Conclusion: The examination makes us to set up a direction of remedy (drug treatment, PCI, CABG) because we can estimate of effect from remedy, lesion site and severity. In addition, we have an advantage that it takes just 3 hours and one-stop in that all of process of examinations run in succession and at the same time. Therefore it shows that the method is useful in one stop evaluation of ischemic heart disease.