• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.3 no.3
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• pp.158-164
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• 1998

We introduce a statistical scheme to classify seabed from acoustic profiling data acquired using Chirp sonar system. The classification is based on grouping of signal traces by similarity index, which is computed using the K-L (Karhunen-Lo$\grave{e}$ve) transform of the Chirp profiling data. The similarity index represents the degree of coherence of bottom-reflected signals in consecutive traces, hence indicating the acoustic roughness of the seabed. The results of this study show that similarity index is a function of homogeneity, grain size of sediments and bottom hardness. The similarity index ranges from 0 to 1 for various types of seabed material. It increases in accordance with the homogeneity and softness of bottom sediments, whereas it is inversely proportional to the grain size of sediments. As a real data example, we classified the seabed off Cheju Island, Korea based on the similarity index and compared the result with side-scan sonar data and sediment samples. The comparison shows that the classification of seabed by the similarity index is in good agreement with the real sedimentary facies and can delineate acoustic response of the seabed in more detail. Therefore, this study presents an effective method for geoacoustic modeling to classify the seafloor directly from acoustic data.

• Journal of Korean Society of Environmental Engineers
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• v.38 no.4
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• pp.184-192
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• 2016

A profiling monitoring system has been developed to monitor the water quality variations according to each water depth and applied for a test-bed. The key parameters were derived to disclose the aquatic ecology and environment of river systems, and the real-time monitoring techniques to profile the variations of each parameter were verified. Monitoring parameters were configured to include water quality, hydrodynamic, and weather conditions. Considering the water depth of the 4 major rivers in Korea, a profiling monitoring system with 1.0 m water depth interval for each monitoring has been established. To understand the real-time variation properties in the Han river, the monitoring system has been installed and operated at the YangHwa-Dock as a test-bed. Based on the results of the detailed analyses on the spring season, as the characteristic diurnal and water-depth-related variations for water temperature, pH, dissolved oxygen (DO), and chlorophyll-a were observed, it could be concluded that the real-time water-depth profiling monitoring system is a very effective tool for the proper management of river environment.

• Journal of the Korean Geophysical Society
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• v.2 no.3
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• pp.209-216
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• 1999

In order to get geologic information necessary for underground installation of water pipe, seismic refraction profiling was applied to the southwest side of the Seomjin River which flows between Namwon-gun, Cholabuk-do and Gokseong-gun, Cholanam-do. Before obtaining the in-line refraction data, walkaway data were recorded with 1 m geophone interval and -36∼+36 m offset range. From the walkaway data, it is interpreted that a dry soil layer with the average velocity of 585 m/s covers wet sediments with the average velocity of 1,326 m/s. The second layer overlies basements nearly horizontally with the average velocity of 4,218 m/s. Refraction profiling of 220 m long with the geophone interval of 2 m is interpreted with the Generalized Reciprocal Method (GRM). Three layers are identified with average velocities of 688 m/s, 1,473 m/s, and 3,776 m/s, respectively. The depth to the bedrock impossible for ripping ranges between two extremes, 1.51∼2.43 m and 2.25∼3.54 m, depending upon thickness of the hidden layer. A typical shortcoming of refraction method, the hidden layer problem, prevents accurate estimation in depth of the second layer.

• Journal of Software Engineering Society
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• v.28 no.1
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• pp.1-6
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• 2019

Google released an initial version of Android that runs Dex(Dalvik Executable) through the Dalvik Runtime. Since Dalvik Runtime is based on interpreter, JIT(Just-in-time) compilation has been applied to improve performance. After Lollipop(Android 5.0) Dalvik Runtime has replaced with ART Runtime which support AOT (Ahead-of-time) compilation of Dex into Native Code. The late st Android has a problem that the application execution speed is slow until the AOT compilation is completed according to the actual usage record after the installation of the app. To improve the problem we have investigate the characteristics of profile that can improve the execution speed of the application and generate the profile automatically. Finally we propose a method that can optimize the application at install time. With the proposed method we can optimize selectively at install time and can help improving the execution speed of the app from the initial execution.

• Journal of Internet Computing and Services
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• v.22 no.3
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• pp.75-83
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• 2021

With the development of the IT industry and the increase of cultural activities, the demand for works increases, and they can be used easily and conveniently in an online environment. Accordingly, copyright infringement is seriously occurring due to the ease of copying and distribution of works. Some special types of Online Service Providers (OSP) use filtering-based technology to protect copyrights, but they can easily bypass them, and there are limits to blocking all illegal works, making it increasingly difficult to protect copyrights. Recently, most of the distributors of illegal works are a certain minority, and profits are obtained by distributing illegal works through many OSP and majority ID. In this paper, we propose a profiling technique for heavy uploader, which is a major analysis target based on illegal works. Creates a feature containing information on overall illegal works and identifies major heavy uploader. Among these, clustering technology is used to identify heavy uploader that are presumed to be the same person. In addition, heavy uploaders with high priority can be analyzed through illegal work Distributor tracking and behavior analysis. In the future, it is expected that copyright damage will be minimized by identifying and blocking heavy uploader that distribute a large amount of illegal works.

• Journal of Digital Convergence
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• v.20 no.4
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• pp.367-376
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• 2022

In traditional criminal cases, there is a limit to information collection because information on the subject of investigation is provided only with personal information held by the national organization of legal. Surface web-based OSINT(Open Source Intelligence), including SNS and portal sites that can be searched by general search engines, can be used for meaningful profiling for criminal investigations. The Korean-style OSINT workflow can effectively profile based on OSINT, but in the case of individuals, OSINT that can be collected is limited because it begins with "name", and the reliability is limited, such as collecting information of the persons with the same name. In order to overcome these limitations, this paper defines information related to individuals, i.e., equivalent information, and enables efficient and accurate information collection based on this. Therefore, we present an improved workflow that can extract information related to a specific person, ie., equivalent information, from OSINT. For this purpose, different workflows are presented according to the person's profile. Through this, effective profiling of a person (individuals) is possible, thereby increasing reliability in collecting investigation information. According to this study, in the future, by developing a system that can automate the analysis process of information collected using artificial intelligence technology, it can lay the foundation for the use of OSINT in criminal investigations and contribute to diversification of investigation methods.

• Journal of Ginseng Research
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• v.46 no.2
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• pp.255-265
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• 2022

Background: Ginsenoside Rb1, a bioactive component isolated from the Panax ginseng, acts as a remedy to prevent myocardial injury. However, it is obscure whether the cardioprotective functions of Rb1 are related to the regulation of endogenous metabolites, and its potential molecular mechanism still needs further clarification, especially from a comprehensive metabolomics profiling perspective. Methods: The mice model of acute myocardial ischemia (AMI) and oxygen glucose deprivation (OGD)-induced cardiomyocytes injury were applied to explore the protective effect and mechanism of Rb1. Meanwhile, the comprehensive metabolomics profiling was conducted by high-performance liquid chromatography and quadrupole time-of-flight mass spectrometry (HPLC-Q/TOF-MS) and a tandem liquid chromatography and mass spectrometry (LC-MS). Results: Rb1 treatment profoundly reduced the infarct size and attenuated myocardial injury. The metabolic network map of 65 differential endogenous metabolites was constructed and provided a new inspiration for the treatment of AMI by Rb1, which was mainly associated with mitophagy. In vivo and in vitro experiments, Rb1 was found to improve mitochondrial morphology, mitochondrial function and promote mitophagy. Interestingly, the mitophagy inhibitor partly attenuated the cardioprotective effect of Rb1. Additionally, Rb1 markedly facilitated the phosphorylation of AMP-activated protein kinase α (AMPKα), and AMPK inhibition partially weakened the role of Rb1 in promoting mitophagy. Conclusions: Ginsenoside Rb1 protects acute myocardial ischemia injury through promoting mitophagy via AMPKα phosphorylation, which might lay the foundation for the further application of Rb1 in cardiovascular diseases.

• Korean Journal of Clinical Laboratory Science
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• v.55 no.2
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• pp.105-112
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• 2023

Leucine-rich repeat kinase 2 (LRRK2) is known to play a crucial role in the pathophysiology of neurodegenerative disorders such as Parkinson's disease. LRRK2 is predominantly expressed in the lung as well as the brain. However, it is unclear whether LRRK2 expression correlates with the pathogenesis of lung squamous cell carcinoma (LUSC). This study analyzes the prognostic significance of LRRK2 in LUSC using the Kaplan-Meier plotter tool. High expression of LRRK2 is known to be associated with a bad prognosis in patients with LUSC. Patients with high LRRK2 expression, tumor mutational burden, high neoantigen load, and even gender correlation reportedly have the worse survival rates. In the gene expression profiling interactive analysis (GEPIA) database, the severity of pathogenesis in LUSC with high LRRK2 expression positively corresponds to a high expression of anti-inflammatory cytokines but not inflammatory cytokines. Similarly, the increased expression of interleukin (IL)10-related genes was shown to be significantly linked in LRRK2-high LUSC patients having a poor prognosis. Moreover, the tumor immune estimation resource (TIMER) database suggests that macrophages are one of the cellular sources of IL10 in LRRK2-high LUSC patients. Collectively, our results demonstrate that the postulated LRRK2-IL10 axis is a potential therapeutic target and prognostic biomarker for LUSC.

• Mass Spectrometry Letters
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• v.3 no.1
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• pp.4-9
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• 2012

• Toxicological Research
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• v.34 no.4
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• pp.373-373
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• 2018