• 대한화학회지
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• 제56권4호
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• pp.530-534
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• 2012

• Journal of Ginseng Research
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• 제38권4호
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• pp.278-288
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• 2014

Background: Panax ginseng Meyer is a traditional medicinal plant famous for its strong therapeutic effects and serves as an important herbal medicine. To understand and manipulate genes involved in secondary metabolic pathways including ginsenosides, transcriptome profiling of P. ginseng is essential. Methods: RNA-seq analysis of adventitious roots of two P. ginseng cultivars, Chunpoong (CP) and Cheongsun (CS), was performed using the Illumina HiSeq platform. After transcripts were assembled, expression profiling was performed. Results: Assemblies were generated from ~85 million and ~77 million high-quality reads from CP and CS cultivars, respectively. A total of 35,527 and 27,716 transcripts were obtained from the CP and CS assemblies, respectively. Annotation of the transcriptomes showed that approximately 90% of the transcripts had significant matches in public databases.We identified several candidate genes involved in ginsenoside biosynthesis. In addition, a large number of transcripts (17%) with different gene ontology designations were uniquely detected in adventitious roots compared to normal ginseng roots. Conclusion: This study will provide a comprehensive insight into the transcriptome of ginseng adventitious roots, and a way for successful transcriptome analysis and profiling of resource plants with less genomic information. The transcriptome profiling data generated in this study are available in our newly created adventitious root transcriptome database (http://im-crop.snu.ac.kr/transdb/index.php) for public use.

• 디지털융복합연구
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• 제19권3호
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• pp.187-194
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• 2021

다양한 형태로 표면 웹에 급증하고 있는 공개정보(OSINT)는 프로파일링 기법을 사용하여 범죄 수사에도 활용할 수 있다. 이러한 기술은 미국 등 외국의 수사기관에서는 상당히 보편화되었으며 일부는 고도화 작업도 진행하고 있다. 반면에 국내의 경우 많이 사용하지 못할 뿐 아니라 수사 인력의 개인적 경험과 지식수준에 따라 획득하는 정보의 양과 질에 있어서 큰 편차를 보이고 있다. 본 논문에서는 가장 잘 알려진 Bazzell의 모델과 달리 한국적 웹 환경을 고려하고 시간 정보까지 제공해주는 한국형 공개정보 기반 프로파일링 기법을 개선된 워크플로우를 중심으로 제시한다. 아울러 프로파일링의 효율성 향상을 목적으로 설계한 검색 데이터베이스의 스키마도 제시한다. 이곳에서 제시한 기법을 사용하면 범죄 수사에서 있어서 일정 수준의 양과 질을 보장하는 검색 결과를 얻을 수 있을 뿐 아니라, 관련 수사 인력에 대한 표준 훈련 과정으로도 사용할 수 있다. 아울러 이 기법을 활용한 범죄 수사의 실효성과 효율성을 높이려면 법률적 기반강화 및 동화된 기술 도입이 더 필요하다.

• 대한수사과학회지
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• 제2권2호
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• pp.92-97
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• 2007

• 한국결정성장학회지
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• 제13권1호
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• pp.19-23
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• 2003

Polished surface of $CsB_{3}O_{5}$ (CBO) has been observed by reflection high energy electron diffraction (RHEED) and X-ray photoelectron spectroscopy (XPS). For comparison, electronic properties of CBO powder have been studied by XPS. It has been found that the crystal surface is covered by thick amorphous layer with chemical composition closely related to that of CBO. Great enrichment of top surface by cesium, ~30 % in reference to the bulk of the modified layer, has been displayed by depth profiling.

• Journal of Microbiology and Biotechnology
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• 제30권3호
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• pp.378-381
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• 2020

Fermentation has recently re-emerged as an approach for improved functionality of food products in addition to the traditional roles such as shelf life, taste, and texture. Here, we report dynamic changes in the metabolite profiles of Achyranthes japonica Nakai by Lactobacillus plantarum fermentation, primarily, the significant increases in representative functional ingredients, 20-hydroxyecdysone and 25S-inokosterone. Additionally, untargeted metabolite profiling showed 58% of metabolites underwent significant alteration. The most dynamic change was observed in cellobiose, which showed a 56-fold increase. Others were sugar alcohols and amino acids, while lyxitol and erythritol that were among the most dynamically down-regulated.

• 인터넷정보학회논문지
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• 제4권2호
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• pp.69-80
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• 2003

프로그램 행위 침입 탐지 기법은 데몬 프로그램이나 루트 권한으로 실행되는 프로그램이 발생시키는 시스템 호출들을 분석하고 프로파일을 구축하여 변형된 공격을 효과적으로 탐지한다. 본 논문에서는 베이지안 네트워크와 다중 서열 정렬을 이용하여 여러 프로세스의 시스템 호출간의 관계를 표현하고, 프로그램 행위를 모델링하여 변형된 이상 침입 행위를 분류함으로써 이상행위를 탐지한다. 제안한 기법을 UNM 데이터를 이용한 시뮬레이션을 수행하였다.

• Journal of Korean Neurosurgical Society
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• 제61권3호
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• pp.376-385
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• 2018

Recent discoveries of brain tumor-related genes and fast advances in genomic testing technologies have led to the era of molecular diagnosis of brain tumor. Molecular profiling of brain tumor became the significant step in the diagnosis, the prediction of prognosis and the treatment of brain tumor. Because traditional molecular testing methods have limitations in time and cost for multiple gene tests, next-generation sequencing technologies are rapidly introduced into clinical practice. Targeted sequencing panels using these technologies have been developed for brain tumors. In this article, focused on pediatric brain tumor, key discoveries of brain tumor-related genes are reviewed and cancer panels used in the molecular profiling of brain tumor are discussed.

• 한국진공학회지
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• 제8권3B호
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• pp.283-289
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• 1999

Multilayer thin film reference materials for the sputter depth profiling analysis are used to calibrate the sputter depth scale by measuring the sputtering rate and to optimize the sputtering conditions for the best depth resolution. Surface analysis group of Korea Research Institute of Standards and science (KRISS) have developed various types of multilayer thin films by using an ion beam sputter deposition and in-situ surface analysis system. The chemical states of the thin films reference materials were certified by in-situ XPS and the thicknesses were certified by transmission electron microscopy (TEM).

• 한국자기공명학회논문지
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• 제17권1호
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• pp.1-10
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• 2013

Metabolomics is the study which detects the changes of metabolites level. Metabolomics is a terminal view of the biological system. The end products of the metabolism, metabolites, reflect the responses to external environment. Therefore metabolomics gives the additional information about understanding the metabolic pathways. These metabolites can be used as biomarkers that indicate the disease or external stresses such as exposure to toxicant. Many kinds of biological samples are used in metabolomics, for example, cell, tissue, and bio fluids. NMR spectroscopy is one of the tools of metabolomics. NMR data are analyzed by multivariate statistical analysis and target profiling technique. Recently, NMR-based metabolomics is a growing field in various studies such as disease diagnosis, forensic science, and toxicity assessment.