• Title/Summary/Keyword: joint detection

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Applicative Value of Serum CA19-9, CEA, CA125 and CA242 in Diagnosis and Prognosis for Patients with Pancreatic Cancer Treated by Concurrent Chemoradiotherapy

  • Gu, Yu-Lei;Lan, Chao;Pei, Hui;Yang, Shuang-Ning;Liu, Yan-Fen;Xiao, Li-Li
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.15
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    • pp.6569-6573
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    • 2015
  • Objective: To evaluate the application value of serum CA19-9, CEA, CA125 and CA242 in diagnosis and prognosis of pancreatic cancer cases treated with concurrent chemotherapy. Materials and Methods: 52 patients with pancreatic cancer, 40 with benign pancreatic diseases and 40 healthy people were selected. The electrochemiluminescence immunoassay method was used for detecting levels of CA19-9, CEA and CA125, and a CanAg CA242 enzyme linked immunoassay kit for assessing the level of CA242. The Kaplan-Meier method was used for analyzing the prognostic factors of patients with pancreatic cancer. The Cox proportional hazard model was applied for analyzing the hazard ratio (HR) and 95% confidential interval (CI) for survival time of patients with pancreatic cancer. Results: The levels of serum CA19-9, CEA, CA125 and CA242 in patients with pancreatic cancer were significantly higher than those in patients with benign pancreatic diseases and healthy people (P<0.001). The sensitivity of CA19-9 was the highest among these, followed by CA242, CA125 and CEA. The specificity of CA242 is the highest, followed by CA125, CEA and CA19-9. The sensitivity and specificity of joint detection of serum CA19-9, CEA, CA125and CA242 were 90.4% and 93.8%, obviously higher than single detection of those markers in diagnosis of pancreatic cancer. The median survival time of 52 patients with pancreatic cancer was 10 months (95% CI7.389~12.611).. Patients with the increasing level of serum CA19-9, CEA, CA125, CA242 had shorter survival times (P=0.047. 0.043, 0.0041, 0.029). COX regression analysis showed that CA19-9 was an independent prognostic factor for patients with pancreatic cancer (P=0.001, 95%CI 2.591~38.243). Conclusions: The detection of serum tumor markers (CA19.9, CEA, CA125 and CA242) is conducive to the early diagnosis of pancreatic cancer and joint detection of tumor markers helps improve the diagnostic efficiency. Moreover, CA19-9 is an independent prognostic factor for patients with pancreatic cancer.

Clinical Significance of Joint Detection of Serum VEGF, SIL-2R and HGF in Patients with Primary Hepatocellular Carcinoma before and after Percutaneous Microwave Coagulation Therapy

  • Chen, Ji-Dong;Xiong, Yan-Qun;Dong, Ke;Luo, Jun;Yue, Lin-Xian;Chen, Qin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.11
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    • pp.4545-4548
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    • 2014
  • Objective: To investigate the changes of serum vascular endothelial growth factor (VEGF), soluble interleukin-2 receptor (SIL-2R) and hepatocyte growth factor (HGF) contents in patients with primary hepatocellular carcinoma (HCC) before and after percutaneous microwave coagulation therapy (PMCT) and determine their clinical significance. Materials and Methods: Fasting venous blood (3 mL) from 81 patients with primary HCC diagnosed by pathology was collected in the mornings 1 day before PMCT, and 1 day, 7 days and 1 month after PMCT, and then the serum was separated and stored in $-70^{\circ}C$. The contents of VEGF, SIL-2R and HGF were detected by enzyme linked immunosorbent assay (ELISA). Results: The serum VEGF, SIL-2R and HGF contents in 81 patients with primary HCC had obviously dynamic changes before and after PMCT. By comparison to 1 day after PMCT with pre-operation, there was no statistical significance regarding VEGF and SIL-2R contents (P>0.05), but HGF content showed significant difference (P<0.01). Compared with pre-operation, VEGF, SIL-2R and HGF contents 7 days and 1 month after PMCT all manifested significant differences (P<0.01). By comparison to 7 days with 1 month after PMCT, there was no statistical significance regarding the VEGF content (P>0.05), whereas SIL-2R and HGF contents showed significant change (P<0.01). Conclusions: The contents of serum VEGF, SIL-2R and HGF have obviously dynamic changes in primary HCC before and after PMCT, and their joint detection is expected to be an effective hematologic evaluation index of PMCT for primary HCC.

Neural Network Model for Partial Discharge Pattern Analysis of XLPE/EPR Interface (XLPE/EPR 계면의 부분방전 패턴 분석을 위한 신경망 모형)

  • Cho Kyung-Soon
    • Journal of the Korea Computer Industry Society
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    • v.6 no.2
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    • pp.279-286
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    • 2005
  • The prefabricated type used generally in Korea to join cable runs on new installations or to repair broken Cable runs on existing installations, because installation is very simple and save time. This type is a permanent, shielded and submersible cable joint for direct burial or vault application. It confirms to the requirements of IEEE std. 404-1993 by factory testing, but many problems of insulated cable systems are caused by internal defects of the joint part which have to be mounted ensile. Faults arise from impurities or voids. A suitable solution for a monitoring of cable joints during the after-laying test and service is partial discharge detection. <중략> $\Phi-q-n$ properties were measured using detection impedance, high pass filter and computerized data acquisition system. Statistic Value like maximum charge, repetition rate, average charge, etc. are calculated. It is possible to quantitative analysis of $\Phi-q-n$ properties from this statistic value and pattern analysis.

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Partial Discharge Detection and Statistic Value Calculation of Power Cable Using Data Acquisition System (데이터 취득 시스템을 이용한 전력케이블의 부분방전 검출과 통계량 계산)

  • 조경순
    • Journal of the Korea Computer Industry Society
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    • v.3 no.12
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    • pp.1651-1658
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    • 2002
  • Recently power cable used generally in Korea, because installation is very simple and it has high stability. It confirms to the requirements of IEEE std. 404-1993 by factory testing, but many problems of insulated cable systems are caused by internal defects of the joint part which have to be mounted ensile. Especially, fault rates are arise from impurities or voids. A suitable solution for a monitoring of power cable during the after-laying test and service is partial discharge detection. The artificial defects between cable joint(EPR) and insulator(XLPE) interface are considered in this research to investigating the partial discharge characteristics. ${\varphi}$-q-n properties were detected using data acquisition system and Maximum charge($q_{max}$), repetition rate(${\={n}$), average charge(${\={q}$), Unbalance rate of ${\={n}$ and ${\={q}$ are calculated in order to analysis partial discharge properties quantitatively from this statistic value.

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Laparoscope Manipulator Control for Minimally Invasive Surgery (최소침습수술을 위한 복강경 매니퓰레이터 제어)

  • Kim, Soo-Hyun;Kim, Kwang-Gi;Jo, Yung-Ho
    • Journal of Institute of Control, Robotics and Systems
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    • v.17 no.7
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    • pp.685-696
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    • 2011
  • An efficient laparoscope manipulator robot was designed to automatically control the position of laparoscope via a passive joint on end-effector position. The end position of the manipulator is controlled to have corresponding velocity defined in the global coordinate space using laparoscopic visual information. Desired spatial position of laparoscope was derived from detected positions of surgical instrument tips, then the clinical viewing plane was moved by visual servoing task. The laparoscope manipulator is advantageous for automatically maintaining clinically important views in the laparoscopic image without any additional operator. A laparoscope is mounted to a holder which is linked to four degree of freedom manipulator via universal joint-type passive rings connection. No change in the design of laparoscope or manipulator is necessary for its application to surgery assistant robot system. Expanded working space and surgical efficiency were accomplished by implementing slant linking structure between laparoscope and manipulator. To ensure reliable positioning accuracy and controllability, the motion of laparoscope in an abdominal space through trocar was inspected using geometrical analysis. A designed laparoscope manipulating robot system can be easily set up and controlled in an operation room since it has a few subsidiary devices such as a laparoscope light source regulator, a control PC, and a power supply.

Tuberculous Tenosynovitis of Flexor Tendon of the Hand (수부 굴곡건에 발생한 결핵성건초염)

  • Min, Hee-Joon;Chung, Yoon-Kyu
    • Archives of Plastic Surgery
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    • v.37 no.5
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    • pp.708-711
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    • 2010
  • Purpose: The sheath of tendon is uncommon site of tuberculous involvement as compared to other parts of the body. Especially, tuberculous tenosynovitis affecting flexor tendon of the hand is a rare condition. In recent years, furthermore, the incidence of tuberculosis is increasing in our country. Tuberculous tenosynovitis is a chronic, slowly destructive disease, which is difficult to diagnosis before operation, but can be definitively diagnosed by the pathologic microscopic examination. Early detection and surgical excision combined with antituberculous medication is important. We report a rare case of tuberculous tenosynovitis of the flexor tendon of the hand. Method: A 12-year-old woman presented with a painless, nontender mass on palmar side between distal interphalangeal joint and proximal area of metacarpophalangeal joint of the left third finger. We had surgical excision of the involved flexor tendon sheath and studied histopathologically. Result: The histopathological findings were chronic granulomatous inflammation with caseating necrosis consistent with tuberculosis. We started antituberculous medication. Conclusion: Tuberculous tenosynovitis is a rare condition, especially involving on the flexor tendon of the hand. But because of increasing tendency of tuberculosis, it is important to differentiate it from other tumors of the hand.

Proposal for Pulse Diagnosis Positions (Chon-Kwan-Chuk) for Pulse Analyzer Based on Literature Review and Anthropometry (문헌고찰 및 실측에 근거한 맥진기 측정시 촌관척 정위에 대한 제안)

  • Kim, Hyun-Ho;Lee, Jeon;Kim, Ki-Wang;Kim, Jong-Yeol
    • The Journal of Korean Medicine
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    • v.28 no.3 s.71
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    • pp.13-22
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    • 2007
  • Objectives : To obtain pulse information, oriental medical doctors usually use the three finger pulse diagnosis method. Although the diagnostic positions are very important, the exact positions are not known because of the uncertain conversion of measures of length (bun, chon, chuk) and misunderstanding of the related concepts of oriental medicine. In this study, we proposed relative positions for the detection of three pulses with a pulse analyzer. Methods : The proposal was made based mainly on several literature reviews, especially the original texts, and the examination of anthropometric characteristics of 78 individuals. Results : The Kwan is the spot where the radial pulse can be felt well near the eminent head of the radius at wrist, high bone. The position of Chon should be apart from Kwan by 6/10 distance between the high bone and wrist joint of each individual. Finally, the position of Chuk is apart from Kwan by 6.5/100 distance between the high bone and the elbow joint of each individual. Conclusions : Adapting those proposed positions for measuring three pulses can provide more consistent information to what an oriental doctor obtains than a pulse analyzer applied to other positions.

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Joint Adaptive Combining and Variable Tap-Length Multiuser Detector for Underwater Acoustic Cooperative Communication

  • Liu, Zhiyong;Wang, Yinghua;Song, Lizhong;Wang, Yinyin;Dai, Fusheng
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.12 no.1
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    • pp.325-339
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    • 2018
  • In this paper, we propose a joint adaptive combining and variable tap-length multiuser detector (MUD) for amplify-and-forward (AF) underwater acoustic cooperative interleave-division multiple access (IDMA) communication system. The proposed MUD jointly realizes tap-length adjustment, adaptive combining, and multiuser detection. In contrast to the existing methods, the proposed detector can adaptively combine the received signals from different nodes at destination, and does not need the assumption that full and perfect channel state information (CSI) of all the links at the receiver is known. Moreover, the proposed detector can adaptively adjust the tap coefficient vector and tap-length of each branch according to the specific channel profile of each branch. Simulation results validate the feasibility and show the advantages of the proposed detector against existing counterparts.

Reliability and Validity of Korean Geriatric Anxiety Inventory(K-GAI) (한국판 노인불안도구(K-GAI)의 신뢰도와 타당도)

  • Kim, Jiyun;Park, Myung Sook;Oh, Doo Nam
    • Journal of muscle and joint health
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    • v.21 no.1
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    • pp.75-84
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    • 2014
  • Purpose: The purpose of this study was to test the validity and reliability of the Korean version of the Geriatric Anxiety Inventory (K-GAI). Methods: Two hundreds and thirty six elderly were participated to test K-GAI. Goldberg's short screening scale for anxiety was tested for criterion validity. Receiver operating characteristics (ROC) analysis was used for measuring sensitivity and specificity. Results: The obtained internal consistency was 0.88. There were significant associations between test and retest results. K-GAI scores was significantly associated with Goldberg's short screening scale for anxiety (r=.694, p<.001). We found that a score of seven and greater was optimal for a criterion of anxiety among elderly Koreans. At this cut point, sensitivity was 78.9% and specificity was 73.1%. Conclusion: The K-GAI displayed good psychometric properties. This tool would be useful for early detection of anxiety among elderly Koreans with various situations including cognitive disorder, low education, or physical disability.

Joint Carrier and Symbol Timing Recovery Using Repetitive Preamble (반복적인 프리엠블을 이용한 반송파 및 심볼 타이밍 동시 복원)

  • 오성근;황병대
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.25 no.8B
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    • pp.1436-1444
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    • 2000
  • In this paper, we propose the joint carrier and symbol timing recovery algorithm using repetitive preamble and differential detection for burst modem. The proposed algorithm can estimate the frequency offset and the symbol timing error regardless of the amount of frequency offset, with a high accuracy, even using very short preamble and at low SNR values. The algorithms for continuous phase frequency shift keying (CPFSK) and phase shift keying (PSK) types are developed. Through computer simulations, we compare the proposed algorithm with the existing algorithms on the estimation accuracy in terms of the preamble length, and analyze those bit error rate(BER) performance.

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