• 한국약용작물학회지
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• 제27권6호
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• pp.419-426
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• 2019

Background: This study aimed to identify antioxidant compounds from the seeds of Dolichos lablab L. by bioassay-guided isolation and recrystallization. Methods and Results: The water layer of D. lablab L. seed extract inhibits intracellular reactive oxygen species (ROS) expressing the 2',7'-dichlorofluorescein diacetate (DCF-DA), Cu/Zn superoxide dismutase (SOD) and catalase genes, as determined by quantitative real-time PCR (qRT-PCR). Two compounds were purified from the water layer of the seeds of D. lablab L. using column chromatography and prep-high performance liquid chromatography (HPLC). Using nuclear magnetic resonance (NMR) and electrospray Ionization mass spectrometry (ESI-MS), their chemical structures were identified as 5-[(2-acetyl-2,3-dihydro-1H-indazol-1-yl)carbonyl]-4,5-dihydro-3H-furan-2-one (C₁₄H₁₄N₂O₄) and stachyose. Conclusions: Two active antioxidant compounds were purified from the seed extract of D. lablab L. seed extract and the structures of these compounds were identified as C₁₄H₁₄O₄N₂ and stachyose.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2015년도 제49회 하계 정기학술대회 초록집
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• pp.61.1-61.1
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• 2015

Nanoscale semiconductor plasma processing has become one of the most challenging issues due to the limits of physicochemical fabrication routes with its inherent complexity. The mission of future and emerging plasma processing for development of next generation semiconductor processing is to achieve the ideal nanostructures without abnormal profiles and damages, such as 3D NAND cell array with ultra-high aspect ratio, cylinder capacitors, shallow trench isolation, and 3D logic devices. In spite of significant contributions of research frontiers, these processes are still unveiled due to their inherent complexity of physicochemical behaviors, and gaps in academic research prevent their predictable simulation. To overcome these issues, a Korean plasma consortium began in 2009 with the principal aim to develop a realistic and ultrafast 3D topography simulator of semiconductor plasma processing coupled with zero-D bulk plasma models. In this work, aspects of this computational tool are introduced. The simulator was composed of a multiple 3D level-set based moving algorithm, zero-D bulk plasma module including pulsed plasma processing, a 3D ballistic transport module, and a surface reaction module. The main rate coefficients in bulk and surface reaction models were extracted by molecular simulations or fitting experimental data from several diagnostic tools in an inductively coupled fluorocarbon plasma system. Furthermore, it is well known that realistic ballistic transport is a simulation bottleneck due to the brute-force computation required. In this work, effective parallel computing using graphics processing units was applied to improve the computational performance drastically, so that computer-aided design of these processes is possible due to drastically reduced computational time. Finally, it is demonstrated that 3D feature profile simulations coupled with bulk plasma models can lead to better understanding of abnormal behaviors, such as necking, bowing, etch stops and twisting during high aspect ratio contact hole etch.

• 한국전자파학회논문지
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• 제16권7호
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• pp.732-739
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• 2005

본 논문에서는 E-평면 T형 분기 도파관을 갖는 Ka대역(20/30 GHz) 다이플렉서의 설계 및 구현에 관해 논하였다. 본 논문의 도파관 다이플렉서는 송신 필터 및 수신 필터를 E-평면 T형 분기 도파관으로 연결하여 E-평면으로 대칭이 되도록 하였다. T형 분기 도파관을 E-평면으로 선택한 이유는 제작시 생기는 절단면을 전류 밀도가 가장 낮은 지역에 두어 PIM(Passive Intermodulation) 레벨을 줄이기 위해서이다. 본 논문의 다이플렉서는 등가 모델을 사용하여 최적 설계를 수행함으로써 해석 시간을 줄이고자 하였다. 또한, 고전력 전송이 가능한 구조로 설계한 후 멀티팩션 해석을 수행하였으며, 해석 결과는 12 dB 마진을 확보하여 ESA/ESTEC 권고 사항을 만족함을 보였다. 제작된 다이플렉서는 전기적 성능 시험 결과를 통해 송수신 대역에서 반사 손실 22 dB 이상, 삽입 손실 0.20 dB 이하, 그리고 -40 dB 이하의 격리도 특성을 가져 요구 사항을 만족함을 보였고, 이로써 설계 결과가 검증되었다.

• 대한본초학회지
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• 제26권2호
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• pp.11-15
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• 2011

Objectives : In the present study, the contents of cinnamic acid and cinnamaldehyde in three different parts of Cinnamomi Ramulus (CR) (the whole body, the bark part, and the wood part) was evaluated using UPLC (ultra performance liquid chromatography) in order to investigate a suitable cutting method. Methods : Analysis was performed on SMART LC with UV detector. Reference compounds were separated on Inertsil ODS-4 column ($2.1mm{\times}50mm$, $3{\mu}m$, GL Science, Japan) using isolation elution with water and acetonitrile each containing acetic acid at a flow rate of $500{\mu}L/min$. Additionally, samples of CR were purchased from pharmacy of medicinal herb. Results : The correlation coefficients of the cinnamic acid and cinnamaldehyde levels showed good linearity ($r^2{\geq}0.9999$) over the linear ranges. Furthermore, the bark part exhibited higher concentration levels of reference compounds than the wood part in all samples. In addition the bark exfoliation rates in oblique and perpendicular-long cut samples of CR were lower than the perpendicular-short cut samples. Conclusions : These results suggested that the optimal cutting method would be able to reduce the bark exfoliation. Therefore, the oblique or perpendicular-long cutting method is considered to be a better cutting type than the perpendicular-short cutting method.

• 한국사회복지학회:학술대회논문집
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• 한국사회복지학회 2002년도 국제학술대회 자료집
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• pp.3-19
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• 2002

The problems and needs of families in Hong Kong are becoming more complex. Traditional family structures and functions are rapidly eroding. Moreover, family problems are further exacerbated by a growing number of socio-economic issues including rising divorce rates and extra-marital affairs. continuous family reunion migration from Mainland China, emotional and financial cost of caring for the older people and the changing economy which has pushed more families into hardship. In effect, more and more families are becoming vulnerable to risk. Traditional family services in Hong Kong are varied in mode, operation and provision, often overlapping in service boundaries with other family-oriented programs. In many instances, family service centers are stretched far beyond their capacity. As a consequence, they become too reactive, remedial and casework dominated. The University of Hong Kong Consultant Team recommended that family service programs have to protect vulnerable families and strengthen family capacities to promote maximum independence. The direction of family services is summarized as: strengthening families; child-centered, family-focused and community-based. New integrative family service centers aim at attaining the principles of promoting accessibility to users with minimum physical, psychological and administrative barriers; early identification of needs and intervention before the further deterioration of problems; integration of services cutting across program boundaries, and partnership between service providers to achieve efficient and effective use of scarce resources. Under the new model, multi-skilled teams can respond more proactively to a wide range of social needs, rather than addressing needs in isolation. To demonstrate the effectiveness of the new model, the consultant team has been commissioned by the government to evaluate the performance of these two-year pilot projects. More importantly, a coherent and family-friendly social policy should be formulated to strengthen family capacity against family-related problems.

• Journal of electromagnetic engineering and science
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• 제9권3호
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• pp.130-140
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• 2009

The design theory and experimental results of a true random noise radar system are presented in this paper. Target range information can be extracted precisely by correlation processing between the delayed reference and the signal received from a target, and the velocity information by the Doppler processing with successive correlation data. A K-band noise radar system was designed using random FM noise signal, and the characteristics of the fabricated system were examined with laboratory and outdoor experiments. A C-band random FM noise signal was generated by applying a low-frequency white Gaussian noise source to VCO(Voltage Controlled Oscillator), and a K-band Tx noise signal with 100 MHz bandwidth was obtained by using a following frequency multiplier. Two modified wave-guide horn arrays were designed and fabricated, and used for the Tx and Rx antennas. The required amount of Tx/Rx isolation was attained by using a coupling cancellation circuit as well as keeping them apart with predetermined spacing. A double down-conversion scheme was used in the Rx and reference channels, respectively, for easy post processing such as correlation and Doppler processing. The implemented noise radar performance was examined with a moving bicycle and a very high-speed target with a velocity of 150 m/s. The results extracted by the Matlab simulation using the logging data were found to be in a reasonable agreement with the expected results.

• 한국전자파학회논문지
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• 제20권2호
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• pp.161-166
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• 2009

본 논문에서는 TDMB와 KPSC를 지원하는 내장형 안테나를 제안한다. 제안된 안테나는 서로 다른 유전율을 가지는 안테나가 결합된 형태이며, 휴대폰에 적합한 작은 사이즈($45{\times}8{\times}8\;mm$, 약 2.8 cc)를 갖는다. TMDB 안테나는 각 셀간의 전류 흐름을 최대화 시킨 맴돌이 구조로 설계되었으며, KPCS 안테나는 휴대폰에 많이 사용되는 PIFA 형태로 설계되었다. TMDB 안테나는 부족한 공진 길이를 보상하기 위해 100 nH 이상의 인덕터가 사용된다. 이때, 인덕터는 높은 주파수 신호를 차단함으로 TDMB에서의 KPCS 주파수 입력은 차단된다. 또한, KPCS 대역에서 TDMB 안테나의 방사부는 기생 소자로 동작하기 때문에 각 밴드 간의 격리도 특성이 우수하다. 제안된 안테나는 CST Microwave Studio를 이용하여 설계하였으며, 전자파 무방향실에서 특성을 측정하였다. 제안된 안테나는 TMDB 대역에서 $-6{\sim}-14\;dBi$의 이득을 가지며, KPCS 대역에서 $-3.5{\sim}-5\;dBi$의 이득을 갖는다.

• 한국항공우주학회지
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• 제39권1호
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• pp.84-89
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• 2011

소형인공위성의 우주추진체로 사용될 홀방식 전기추력기의 서브시스템으로 제논연료공급장치가 개발되었다. 제논연료공급장치는 연료저장탱크에서 추력기의 양극과 음극에 낮은 압력으로 연료를 공급하게 된다. 추력기는 양극과 음극에서 독립적으로 정밀한 연료의 유량제어를 요구하고 있다. 연료의 유량은 양극과 음극에 각각 위치한 오리피스와 차단밸브를 통해 축압탱크의 압력을 변경함으로서 조절된다. 본 논문은 제논연료공급장치의 부품선정을 포함한 설계와 성능검증 및 기능시험에 대한 내용을 다루고 있다.

• 한국소음진동공학회논문집
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• 제22권1호
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• pp.22-28
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• 2012

While a dash panel component, close to passengers, plays a very important role to protect heat and noise from a power train, it is also a main path that transfers vibration energy and eventually radiates acoustic noise into the cavity. Therefore, it is important to provide optimal design schemes incorporating sound packages such as a dash isolation pad and a floor carpet, as well as structures. The present study is the extension of the previous investigation how design variables affect sound radiation, which was carried out using the simple plate and framed system. A novel FE-SEA hybrid simulation model is used for this study. The system taken into account is a dash panel component of a sedan vehicle, which includes front pillars, front side members, a dash panel and corresponding sound packages. Design variables such as panel thicknesses and sound packages are investigated how they are related to two main NVH indexes, sound radiation power(i.e. structure-borne) and sound transmission loss(i.e. air borne). In the viewpoint of obtaining better NVH performance, it is shown that these two indexes do not always result in same tendencies of improvement, which suggests that they should be dealt with independently and are also dependent on frequency regions.

• 생약학회지
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• 제41권2호
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• pp.73-88
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• 2010

Traditionally, the root of Lithospermum erythrorhizon Sieb. et Zucc(L.E) has been used as efficacious therapy for inflammation, burns, frostbite and skin ailments (e.g eczema and psoriasis). It contains isohexenylnaphthoquinone derivatives (shikonin and its esters) and furylhydroquinones (shikonofurans) in lipophilic fractions and caffeic acid oligomers (rosmarinic acid, lithospermic acid B) in polar fractions. Recently, new preparative isolation and analysis procedures of shikonin along with its oligomers from the extract of L. erythrorhizon by the combination of high-speed counter-current chromatography with high-performance liquid chromatography-diode array detection have also been introduced. Although there have been many reports on the wound healing, antiinflammatory, and anticancer effects, the research on the effects of anti-atopic dermatitis of the root of L. erythrorhizon were relatively scarce. However, in recent years, new information gathered from research efforts, on the anti-atopic dermatitis properties of the extract or constituents of L. erythrorhizon has been accumulated. In this paper, the findings and advance on the in vitro and in vivo activities of L. erythrorhizon and its constituents especially focused on antiinflammatory and anti-atopic dermatitis effects are summarized. The phytochemical constituents of L. erythrorhizon or its tissue cultures are also presented. Although there are few to verify or refute its activity in human, one result of clinical study of the extract of L. erythrorhizon on the atopic dermatitis patients was introduced to assess the possibility of its clinical use. The reported mechanisms of action and in vivo pharmacological studies in different animal models for the various types of extracts or constituents of L. erythrorhizon are supportive of its therapeutic potential or dietary supplement, however, more evidence from clinically relevant models, as well as systemic studies on the active constituents or the various types of standardized extracts at the cellular and molecular level, are required.