• Journal of Pharmaceutical Investigation
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• 제29권2호
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• pp.127-136
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• 1999

In order to eliminate demerits of conventional dosage forms, dipotassium glycyrrhizate was formulated as a slim mucoadhesive film type dosage form. The mucoadhesive drug layer gel containing dipotassium glycyrrhizate was prepared using $Noveon^{\circledR}$ AA-1, hydroxypropylcellulose-M, ethylcellulose N 100 and citric acid, and the protective layer gel by using ethylcellulose N 100, $Eudragit^{\circledR}$ RS and castor oil. The viscosity of drug layer gel of mucoadhesive film was enhanced as the increased amount of $Noveon^{\circledR}$ AA-1 or hydroxypropyl cellulose-M. The drug content was unifonnly $1160{\pm}14.6\;{\mu}g$, and was varied within 3.5%. The optimum film dosage form showed a good fluidity and malleability of drug layer, with 179 g of thickness, pH 5.7, 411 min of in vitro adhesion time and 172 g in gravity adhesive strength. The release time of drug from the mucoadhesive film was significantly shorter but was delayed when polymers such as ethylcellulose was added. From these results, the new mucoadhesive film may be effective for the treatment of aphthous stomatitis.

• Journal of Plant Biology
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• 제17권4호
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• pp.11-17
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• 1974

The present investigation dealt with observation and experiments concerning the growth and differentiation of hop plant, using the varieties of Cascade(C), Shinshuwase(Sh), and Hallertau(H). The results were as follows: (1) Life cycle of hop plants. The annual growth period of hop plant was devided chiefly into 3 phases, dormant, vegetative and reproductive. (2) Growth of main stem. The hop vine begun to grow in the middle of May and grow vigorousely in the middle and latter of June, then gradually decline or stops at the middle of July and the early of August. (3) Growth of lateral vines. By the statistical analysis, it is judged that the varieties of H and Sh were more grown than that of C. H and Sh were not significant, but H and Sh from C were significant in 5% level. (4) Fresh weight and water content of hop cone. Hop cone in fresh weight of C variety was higher than those of other two varieties and water content of hop cone was decreased with time elapse in three races together. (5) Growing point. Histological view of hop varities in each was different. C showed form of sweet potato, H showed form of round, and Sh showed form of ellipse. (6) Shape of the leaf. C and H were 3 lobes, but Sh is 3∼5 lobes. Generally, the color is dark green. (7) Hop cones. Hop cones are as follows.

• 한국통신학회논문지
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• 제33권11C호
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• pp.851-859
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• 2008

본 논문에서는 Cyclic prefix 형태의 보호구간이 비동기 MC-CDMA 시스템에 미치는 영향을 주파수 선택적 다경로 페이딩 채널에 대하여 분석한다. 이를 위해 보호구간을 갖는 비동기 MC-CDMA 시스템의 평균 오류율(BER) 성능을 Closed-form으로 유도한다. 또한 MC-CDMA 시스템의 주파수 다이버시티는 경로 다이버시티와 같음을 확인한다. 본 논문에서 제안한 분석 기법을 보호구간이 없는 경우로 확장하고, 분석 결과를 통해 보호구간이 ISI(InterSymbol Interference)와 ICI(InterCarrier Interference)의 영향을 완화시키기 위해서 뿐만이 아니라 원하는 신호 성분의 전력 감쇄를 완화시키기 위해 MC-CDMA 시스템에 필요함을 확인한다. 또한 성능 분석의 정확성을 모의실험을 통하여 검증하였다.

• Journal of Pharmaceutical Investigation
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• 제37권1호
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• pp.1-5
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• 2007

Solid dispersions of piroxicam were prepared by melting method using poloxamer as a carrier. The results of DSC and XRD studies showed that the amorphous farm of piroxicam coexisted with the crystalline form in the solid dispersions. However, the ratio of crystalline form of piroxicam in the solid dispersion prepared by melting method decreased in comparison with the same ratio of the solid dispersion prepared by solvent method. As the ratio of poloxamer in the solid dispersion increased, the ratio of the amorphous form of piroxicam in the solid dispersion increased. The dissolution rate of piroxicam from the solid dispersions was significantly higher than that from piroxicam powder. In comparison to the solid dispersion prepared by solvent method, the dissolution rate of piroxicam from the solid dispersion prepared by melting method was higher. As the ratio of poloxamer in the solid dispersion prepared by melting method increased, the initial dissolution rate decreased, however, the total amount dissolved at the end of the study increased.

• 건축역사연구
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• 제25권6호
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• pp.35-44
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• 2016

The purpose of this study is to identify the aspect of expression about the form of Shwedagon Pagoda as well as to find out its meanings. The aesthetic value of Shwedagon Pagoda appears as the worship and infinite respect to Buddha realizing its beautiful sacred symbol. The meaning of Shwedagon Pagoda is to progress in keeping pace with the specific flexibility of Buddhism in Myanmar developing Buddhistic diversity and accepting its active changes. As time passes, Shwedagon Pagoda has been transformed. It is because that Myanmar's architecture was developed independently being affected by India with the introduction of Buddhism, and accepted it through autonomous reinterpretation. Then, the function of the worship space surrounding Shwedagon was extended and its annexes and statues of the Buddha were built; its scale became larger. This study shows the comparison between Shwezigon Pagoda and Shwedagon Pagoda. This method of investigation reveals that the formal changes of Shwedagon makes it transform to concise composition and develop aesthetical component giving the sense of vertical rise.

• Structural Engineering and Mechanics
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• 제74권3호
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• pp.325-339
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• 2020

This study presents a practical application of topology optimization (TO) technique to seek the best form of perforated steel plate shear walls (PSPSW) in simple frames. For the numerical investigation, a finite element model is proposed based on the recent particular form of PSPSW that is called the ring-shaped steel plate shear wall. The TO is applied based on the sensitivity analysis to maximize the reaction forces as the objective function considering the fracture tendency. For this purpose, TO is conducted under a monotonic and cyclic loading considering the nonlinear behavior (material and geometry) and buckling. Also, the effect of plate thickness is studied on the TO results. The final material volume of the optimized plate is limited to the material volume of the ring-shaped plate. Finally, an optimized plate is introduced and its nonlinear behavior is investigated under a cyclic and monotonic loading. For a more comprehensive view, the results are compared to the ring-shaped and four usual forms of SPSWs. The material volume of the plate for all the models is the same. The results indicate the strength, load-carrying, and energy dissipation in the optimized plate are increased while the fracture tendency is reduced without changing the material volume.

• 생약학회지
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• 제18권2호
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• pp.89-93
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• 1987

Chemical investigation of the inhibitory compound on leucocyte migration from Melilotus officinalis has led to the isolation and characterization of azukisaponin V $(3-O-[{\alpha}-L-rhamonopyranosyl(1{\rightarrow}2)-{\beta}-D-glucopyransosyl(1{\rightarrow}2)-{\beta}-D-glucuronopyranosyl]-soyasapogenol B)$ as the carboxylate form, which exhibits potent leucocyte migration inhibitory activity at a dose of 6mg/rat.

• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2001년도 추계학술발표대회 논문집
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• pp.91-94
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• 2001

This paper presents the analytical investigation pertaining to the local buckling behavior of orthotropic channel section compression members stiffened with unsymmetric stiffeners at its free edges. In the analysis, tile edge stiffener is modeled as a beam element or a plate element. The result of both cases is presented in graphical form so that the effects of edge stiffeners on the local buckling strength of edge stiffened channel section member can be found.

• 품질경영학회지
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• 제26권4호
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• pp.219-238
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• 1998

The objective of this study was to establish a procedure of concurrent engineering which can be easily a, pp.icable in Korean industry. An investigation of various techniques of concurrent engineering was conducted. Problems of Korean companies which can be resolved by concurrent engineering techniques were identified. Techniques which can resolve these problems at the relatively low cost and without complicated computer facilities were selected and form a procedure for this study. The procedure was a, pp.ied to a manufacturing company for validation. It was found that this procedure can substantially reduce time and cost of R&D and manufacturing.

• Nuclear Engineering and Technology
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• 제4권3호
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• pp.194-202
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• 1972

방사성 폐액처리에서 나오는 방사성 Sludge의 Solar energy에 의한 고화 처리방법은 가장 효과적이고 경제적인 처리방법의 하나이다. 본연구를 통해서 Sludge의 고화처리는 3月부터 8月사이가 가장 적정기이고, 또 Mass-transfer방법에 의해 증발량 추정에 대한 실험식을 유도하였다.