• Title/Summary/Keyword: investigation challenges

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Basic Study on the Trend Analysis and Direction of Remodeling of High Schools (고등학교 리모델링의 경향분석 및 방향설정에 관한 기초적 연구 -서울시 고등학교 사례를 중심으로-)

  • Yoon, Jun-Seon
    • Journal of the Korean Institute of Educational Facilities
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    • v.14 no.2
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    • pp.16-24
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    • 2007
  • The study is intended to analyze the tendency of the remodeling for the high schools in Seoul, with the potential challenges thereof, determining the principle for the remodeling projects in the days to come. To that end, the analysis to identify the school facilities in a bid to accommodate the current curriculum was conducted, along with the case study on remodeling projects. The $7^{th}$ curriculum demands for a significant change in school facilities. The number of student in a class that has been on the decline, despite of steady increase in number of schools, and the population getting concentrated in Seoul and its suburbs have resulted in an increase in number of class. Consequently, more investment in the facility, rather than improving a substantial education environment, has been made. The study, thus, is aimed at identifying the facility of the high school required by the $7^{th}$ curriculum, as well as implementing a fact-finding investigation into the remodeling works far high schools in Seoul so as to come up with the guideline for remodeling projects.

Prospects and Challenges of Social Media Marketing: Study of Indian Management Institutes

  • Bhandari, Ravneet Singh;Bansal, Sanjeev
    • Asian Journal of Business Environment
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    • v.8 no.4
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    • pp.5-15
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    • 2018
  • Purpose - The research aimed to reveal real decisional behavioral of management institutes in India for social media marketing usage, and analyses of empirical elements of social media consumption pattern. Research design, data, and methodology - The investigation was based around a research methodology using quantitative analysis with appropriate statistical techniques on random surveys of consumers, detailed exploratory and confirmatory factor analyses are applied to assess the empirical validity of the model and multiple regression employed using R studio edition to validate the reliability of the developed models. Results - A new conceptual framework is proposed - the management institutions decision model, providing a tool for effective and more focused decision-making strategies for developing better utilization techniques for social media. Management institutions have different requirements based upon objectives and resources available. The evidence suggests that the administrators need to be more aware of consumer indicators when targeting and designing social media marketing strategy. Conclusions - The research was based on samples and not the entire population of target consumers, providing limitations. As an inferential statistical method was chosen, the results might be susceptible to inaccuracy. The model developed from different age users, thereby providing rich perspectives into social media usage pattern.

Investigation into the Relationship between Self-Esteem and Environmental Behavior and Research into Self-Esteem in High School Students (자아 존중감이 환경 행동에 미치는 영향 고찰과 고등학생의 자아 존중감에 관한 실태 조사)

  • 박진희;장남기
    • Hwankyungkyoyuk
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    • v.10 no.2
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    • pp.63-74
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    • 1997
  • 'Self-esteem' is defined as 'the lived status of one's individual competence and personal worthiness in dealing with the challenges of Life over Time' and high self-esteem is associated with self-confidence, effectively coping, well-being, and responsibility. The first purpose of this study was to identify the concept of self-esteem and to investigate the relationship with self-esteem and responsible environmental behaviors (REB). According to the results, it was found that 'self-esteem' is considered as one of the influential factors on REB and self-esteem enhancement is essential for the responsible choice and determination of environments. The second purpose was to analyse the level of self-esteem in High School students. The mean scores of merits and demerits for all the students involved (402) were 14.58 and 14.91 respectively. By applying the t-test, the two scores were not so different: thus the mean of self-esteem was found to be at a median level. The number of adove-average, average and below-average levels were 114, 163 and 125 respectively. From now on, the development of strategies to enhance self-esteem is urgently needed.

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Estimation of natural radionuclide and exhalation rates of environmental radioactive pollutants from the soil of northern India

  • Devi, Vandana;Chauhan, Rishi Pal
    • Nuclear Engineering and Technology
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    • v.52 no.6
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    • pp.1289-1296
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    • 2020
  • The estimation of radioactivity level is vital for population health risk assessment and geological point of view and can be evaluated as rate of exhalation and source concentration (226Ra, 232Th and 40K). The present study deals with the soil samples for investigation of radionuclides content and exhalation rates of radon -thoron gas from different sites in northern Haryana, India. Absorbed dose and associated index estimated in the present study are the measures of environmental radioactivity to inhalation dose. Effective doses received by different tissues and organs by considering different occupancy and conditions are also measured. Exhalation rates of radon and thoron are measured with active scintillation monitors based on alpha spectroscopy namely scintillation radon (SRM) and thoron (STM) monitors respectively. Sample height was optimized before measurement of thoron exhalation rate using STM. Average values of radon and thoron exhalation are found 16.6 ± 0.7 mBqkg-1h-1 and 132.1 ± 2.6 mBqm-2s-1 respectively. Also, a simple approach was also adopted, to evaluate the thoron exhalation which accomplished a lot of challenges, the results are compared with the data obtained experimentally. The study is useful in the nationwide mapping of radon and thoron exhalation rates for understanding the environmental radioactivity status.

Molecular Diagnosis for Personalized Target Therapy in Gastric Cancer

  • Cho, Jae Yong
    • Journal of Gastric Cancer
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    • v.13 no.3
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    • pp.129-135
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    • 2013
  • Gastric cancer is the second leading cause of cancer-related deaths worldwide. In advanced and metastatic gastric cancer, the conventional chemotherapy with limited efficacy shows an overall survival period of about 10 months. Patient specific and effective treatments known as personalized cancer therapy is of significant importance. Advances in high-throughput technologies such as microarray and next generation sequencing for genes, protein expression profiles and oncogenic signaling pathways have reinforced the discovery of treatment targets and personalized treatments. However, there are numerous challenges from cancer target discoveries to practical clinical benefits. Although there is a flood of biomarkers and target agents, only a minority of patients are tested and treated accordingly. Numerous molecular target agents have been under investigation for gastric cancer. Currently, targets for gastric cancer include the epidermal growth factor receptor family, mesenchymal-epithelial transition factor axis, and the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathways. Deeper insights of molecular characteristics for gastric cancer has enabled the molecular classification of gastric cancer, the diagnosis of gastric cancer, the prediction of prognosis, the recognition of gastric cancer driver genes, and the discovery of potential therapeutic targets. Not only have we deeper insights for the molecular diversity of gastric cancer, but we have also prospected both affirmative potentials and hurdles to molecular diagnostics. New paradigm of transdisciplinary team science, which is composed of innovative explorations and clinical investigations of oncologists, geneticists, pathologists, biologists, and bio-informaticians, is mandatory to recognize personalized target therapy.

Challenges and Outlook for the UICC-Asian Regional Office

  • Akaza, Hideyuki
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4935-4937
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    • 2013
  • At the United Nations High-level Meeting on Non-communicable Disease Prevention and Control in 2011 the link between health and socioeconomic issues was raised, becoming a global political issue. Health equity is one challenge that has hitherto not been addressed directly, although there is a growing shared recognition that cancer in Asia is an urgent social issue. At the UICC-ARO we are working to promote and widen networks of individuals and organizations in Asia and involve them in cooperation for this purpose. As part of our current activities, we are addressing the question of the "Economic burden of cancer in Asian countries: How should we face the current situation?" from a variety of angles and seeking to bring together a wealth of multidisciplinary knowledge about cancer in Asia and its related socioeconomic factors. It is essential to ensure that the real picture of cancer in Asia, which is currently not accurately understood, is conveyed clearly to all concerned, and also that the differences between cancer in Asia and in the West are highlighted.

Senior Level Designers - Designers Shared Leadership Model in Interior Design Companies: The Consequence of an Investigation among Leading Designers in Nine Companies in Korea

  • Choi, Seung-Pok
    • International Journal of Contents
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    • v.8 no.1
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    • pp.95-99
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    • 2012
  • Interior design companies in Seoul, Korea, senior level designers-designers shared leadership model has not been implemented by the design management. The whole interior design companies are worked each by a leadership team consisting of senior level designers, contractors and designers, being accountable for company, workers, and budgets. The results for workers' opinion in leadership positions were evaluated. All 154 leading workers of all professional teams were anonymously interviewed with a questionnaire containing 45 items regarding their satisfaction with this new shared leadership model. The response rate was 96.2%. After all, the leading workers were satisfied with the shared leadership model both in their own designing practice and in general. Non-design workers were comprehensively more in favor of quite a few aspects of shared leadership than senior level designers, but even the latter reported to be generally satisfied. However, both professional teams estimated leading positions to be only modestly attractive. The consequences yield some evidence that the transform from traditional leadership models to the senior level designers -designers shared leadership model may have advantages in the management of interior design companies. Furthermore, there is a need for greater clarity about precisely what we mean by shared leadership and also a deeper exploration of potential challenges arising from shared leadership models if we are to try to come to terms with their practice.

Metagenomic investigation of gastrointestinal microbiome in cattle

  • Kim, Minseok;Park, Tansol;Yu, Zhongtang
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.11
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    • pp.1515-1528
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    • 2017
  • The gastrointestinal (GI) tract, including the rumen and the other intestinal segments of cattle, harbors a diverse, complex, and dynamic microbiome that drives feed digestion and fermentation in cattle, determining feed efficiency and output of pollutants. This microbiome also plays an important role in affecting host health. Research has been conducted for more than a century to understand the microbiome and its relationship to feed efficiency and host health. The traditional cultivation-based research elucidated some of the major metabolism, but studies using molecular biology techniques conducted from late 1980's to the late early 2000's greatly expanded our view of the diversity of the rumen and intestinal microbiome of cattle. Recently, metagenomics has been the primary technology to characterize the GI microbiome and its relationship with host nutrition and health. This review addresses the main methods/techniques in current use, the knowledge gained, and some of the challenges that remain. Most of the primers used in quantitative real-time polymerase chain reaction quantification and diversity analysis using metagenomics of ruminal bacteria, archaea, fungi, and protozoa were also compiled.

Challenges in the Toxicological(Mutagenic and Teratogenic)/Environmental methods under the GLP system

  • Andrson, D.
    • Proceedings of the Korea Society of Environmental Toocicology Conference
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    • 2002.10a
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    • pp.107-116
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    • 2002
  • GLP regulations were initially “promulgated to address assuring the validity of data in the wake of investigations by EPA and FDA during the mid -1970's which revealed that some studies submitted to the agencies had not been conducted in accordance with acceptable laboratory practices.” [1] In the early 1970s, results of an investigation by the FDA in about 40 laboratories revealed many cases of badly managed studies, poor training of personnel and some cases of deliberate fraud. The general findings were that there were poorly trained study directors and study personnel, poorly designed protocols, protocols not followed, procedures not conducted as described, raw data badly collected, data not correctly identified, data without traceability, data not verified and approved by responsible persons, lack of standardised procedures, poor animal husbandry, inadequate characterisation of test items and test systems, inadequate resources, equipment poorly calibrated or otherwise qualified, reports not sufficiently verified, not an accurate account of the actual study, not a proper reflection of raw data and inadequate archiving of data. These problems are not just past history, since they resurface time and time again, even in quite recent times as the experience of GLP inspectors shows [1]. The GLPs specify minimum practices and procedures in order to ensure the quality and integrity of data submitted in accordance with a regulatory requirement

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Study on the Trend Analysis and Direction of Remodeling of Middle Schools - Case Study of Middle Schools in Gyeonggi Province - (중학교(中學校) 리모델링의 경향분석 및 방향설정에 관한 연구 - 경기도 중학교 사례를 중심으로 -)

  • Yoon, Jun-Seon
    • Journal of the Korean Institute of Educational Facilities
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    • v.13 no.1
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    • pp.5-16
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    • 2006
  • The study is intended to analyze the tendency of the remodeling for the middle schools in Gyeonggi Province, with the potential challenges thereof, thereby determining the principle for the remodeling projects in the days to come. To that end, the analysis to identify the school facilities in a bid to accommodate the current curriculum was conducted, along with the case study on remodeling projects. The $7^{th}$ curriculum demands for a significant change in school facilities. The number of student in a class that has been on the decline, despite of steady increase in number of schools, and the population getting concentrated in Seoul and its suburbs have resulted in an increase in number of class. Consequently, more investment in the facility, rather than improving a substantial education environment, has been made. The study, thus, is aimed at identifying the facility of the middle school required by the $7^{th}$ curriculum, as well as implementing a fact-finding investigation into the remodeling works for middle schools in Gyeonggi Province so as to come up with the guideline for remodeling projects.