• 의료법학
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• 제11권1호
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• pp.117-143
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• 2010

Along with the development of digital technologies, the information obtained during the medical procedures was working as a source of valuable assets. Especially, the secondary use of personal health information gives the ordeal to privacy protection problems. In korea, the usage of personal medical information is basically regulated by the several laws in view of general and administrative Act like Medicine Act, Public institutions' personal information protection Act, Information-Network Act etc. There is no specific health information protection Act. Health information exchange program for the blood donor referral related with teratogenic drugs and contagious disease and medical treatment reporting system for income tax convenience are the two examples of recently occurred secondary use of health information in Korea. Basically the secondary use of protected health information is depend on the risk-benefit analysis. But to accomplish the minimal invasion to privacy, we need to consider collection limitation principle first. If the expected results were attained with alternative method which is less privacy invasive, we could consider the present method is unconstitutional due to the violation of proportionality rule.

• 대한치과의사협회지
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• 제51권9호
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• pp.501-510
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• 2013

This paper reviews a current view regarding the association between periodontitis and atherosclerotic cardiovascular diseases (ACVD). Many evidences have suggested that there exist biological mechanisms by which periodontitis can lead to ACVD. Periodontal infection can lead to direct bacterial invasion into endothelial tissues through the blood stream, then the bacteria can activate the host inflammatory response followed by atheroma formation, maturation and exacerbation. Also, chronic periodontal infections may indirectly induce endothelial activation or dysfunction through a state of systemic inflammation as evidenced by elevated plasma acute proteins, IL-6 and fibrinogen as well. There is moderate evidence that periodontal treatment can reduce systemic inflammation and improvement of both clinical surrogate markers. But there is no periodontal intervention study available on primary ACVD prevention. There is consistent and strong epidemiologic evidence, including in vitro, animal and clinical studies, that periodontitis imparts increased risk for future ACVD. However, evidences from intervention trials to date are not sufficient to confirm the multi directional causality of periodontitis in ACVD etiology. Well-designed intervention trials on the impact of periodontal treatment on the prevention of ACVD outcomes are needed.

• 한국인터넷방송통신학회논문지
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• 제14권4호
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• pp.227-232
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• 2014

인터넷 기술이 발전되고, 보편화 되면서 상업과 자본의 대형화가 이루어져 대형 포털 사이트들이 등장하고 성장하게 되면서 인터넷상에서 시간이 흘러도 삭제되지 않는 개인정보 때문에 심각한 사생활 침해문제 등 새로운 위험요소가 제기되고 있다. 특히 마녀사냥 같은 개인의 신상 털기는 피해 당사자가 정상적인 생활이 불가능할 정도의 중대한 문제로 부각되고 있다. 따라서 본 논문에서는 국내외 사례분석을 통하여 개인이 온라인 사이트에 올라와 있는 자신과 관련된 정보 삭제를 요구할 수 있는 권리의 필요성과 국내 도입방안 및 적용에 관한 개선방안을 제안한다.

• 디지털산업정보학회논문지
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• 제11권3호
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• pp.53-62
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• 2015

Recently, number of tablet or Smartphone users increased significantly in domestic and around the world. But violation of personal information such as leakage, misuse and abuse are constantly occurring by using mobile devices which is very useful in our society. Therefore, in this paper it will talk about the problems in the network environment of the mobile environment such as tablet and Smartphone, Mobile Malware, hacking of the public key certificate, which could be potential threat to mobile environment. This thesis will research for people to use their mobile devices more reliable and safer in mobile environment from invasion and leakage of personal information. In order to use Smartphone safely, users have to use Wi-Fi and Bluetooth carefully in the public area. This paper will research how to use App safely and characteristic of risk of worm and Malware spreading. Because of security vulnerabilities of the public key certificate, it will suggest new type of security certification. In order to prevent from the information leakage and infect from Malware in mobile environment without knowing, this thesis will analyze the improved way to manage and use the mobile device.

• Asian Pacific Journal of Cancer Prevention
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• 제16권6호
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• pp.2187-2191
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• 2015

Background: Protrusive structures formed by migrating and invading cells are termed lamellipodia, filopodia, invadopodia and podosomes. Lamellipodia and filopodia appear on the leading edges of migrating cells and function to command the direction of the migrating cells. Invadopodia and podosomes are special F-actin-rich matrix-degrading structures that arise on the ventral surface of the cell membrane. Invadopodia are found in a variety of carcinomatous cells including squamous cell carcinoma of head and neck region whereas podosomes are found in normal highly motile cells of mesenchymal and myelomonocytic lineage. Invadopodia-associated protein markers consisted of 129 proteins belonging to different functional classes including WASP, NWASP, cortactin, Src kinase, Arp 2/3 complex, MT1-MMP and F-actin. To date, our current understanding on the role(s) of these regulators of actin dynamics in tumors of the orofacial region indicates that upregulation of these proteins promotes invasion and metastasis in oral squamous cell carcinoma, is associated with poor/worst prognostic outcome in laryngeal cancers, contributes to the persistent growth and metastasis characteristics of salivary gland adenoid cystic carcinoma, is a significant predictor of increased cancer risk in oral mucosal premalignant lesions and enhances local invasiveness in jawbone ameloblastomas.

• 교육시설 논문지
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• 제23권1호
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• pp.23-32
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• 2016

This research aims to securement of crime prevention for school violence and invasion from outside etc. For crime prevention efficiency secure, It has purpose for school current state comprehension and prevention essential elements deduction autonomously etc. Furthermore, school facility crime dangerousness evaluation checklist is looked for autonomous monitoring tools. This checklist made from analysis of frequency, importance and check availability of 6 native and foreign existing CPTED evaluation's 360 indexes. Then, 81 indexes was derived from analysis, and that indexs verified through focus group interview. Finally, total 47 articles checklist emerged with general details, external school, internal school, and school administrative managements. Through this checklist, school can select essential elements of the preferential crime prevention autonomously, and so it is expected to prompt improvement of crime dangerousness elements, school violence and reduction of crime rate.

• Asian Pacific Journal of Cancer Prevention
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• 제17권1호
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• pp.25-35
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• 2016

Lymph node metastasis (LNM) in papillary thyroid cancer (PTC) has been shown to be associated with increased risk of locoregional recurrence, poor prognosis and decreased survival, especially in older patients. Hence, there is a need for a reliable biomarker for the prediction of LNM in this cancer. MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene translation or degradation and play key roles in numerous cellular functions including cell-cycle regulation, differentiation, apoptosis, invasion and migration. Various studies have demonstrated deregulation of miRNA levels in many diseases including cancers. While a large number of miRNAs have been identified from PTCs using various means, association of miRNAs with LNM in such cases is still controversial. Furthermore, studies linking most of the identified miRNAs to the mechanism of LNM have not been well documented. The aim of this review is to update readers on the current knowledge of miRNAs in relation to LNM in PTC.

• Journal of Yeungnam Medical Science
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• 제32권1호
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• pp.38-41
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• 2015

Pyogenic liver abscess with metastatic septic complications is a rare and serious infectious disease if not treated properly. Pyogenic liver abscesses are caused by bacterial, fungal, or parasitic organisms. Escherichia coli used to be the predominant causative agent, but Klebsiella pneumoniae emerged as a major cause in the 1990s. Liver abscesses are caused by hepatic invasion via many routes, such as, the biliary tree, portal vein, hepatic artery, direct extension, or penetrating trauma. Furthermore, diabetes mellitus and malignant conditions are established important risk factors of K. pneumoniae liver abscesses and of septic metastasis, and several recent studies have asserted that K. pneumoniae liver abscess might be a presentation of occult or silent colon cancer. We report a case of K. pneumoniae liver abscess, metastatic septic pulmonary embolism, and endophthalmitis associated with diabetes and advanced gastric cancer.

• 한국축산식품학회지
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• 제33권3호
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• pp.395-402
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• 2013

Sodium chloride is used to improve various properties of processed meat products, e.g., taste, preservation, water binding capacity, texture, meat batter viscosity, safety, and flavor; however, many studies have shown that sodium chloride increases the resistance of many foodborne pathogens to heat and acid. Listeria monocytogenes has been isolated from various readyto- eat (RTE) meat and dairy products formulated with sodium chloride; therefore, the objective of this paper was to review the effects of sodium chloride on the physiological characteristics of L. monocytogenes. The exposure of L. monocytogenes to sodium chloride may increase biofilm formation on foods or food contact surfaces, virulence gene transcription, invasion of Caco-2 cells, and bacteriocin production, depending on L. monocytogenes strain and serotype as well as sodium chloride concentration. When L. monocytogenes cells were exposed to sodium chloride, their resistance to UV-C irradiation and freezing temperatures increased, but sodium chloride had no effect on their resistance to gamma irradiation. The morphological properties of L. monocytogenes, especially cell elongation and filament formation, also change in response to sodium chloride. These findings indicate that sodium chloride affects various physiological responses of L. monocytogenes and thus, the effect of sodium chloride on L. monocytogenes in RTE meat and dairy products needs to be considered with respect to food safety. Moreover, further studies of microbial risk assessment should be conducted to suggest an appropriate sodium chloride concentration in animal origin foods.

• 대한두개안면성형외과학회지
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• 제17권2호
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• pp.90-92
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• 2016

Pleomorphic adenoma is the most common type of salivary gland tumor and the most common tumor of the parotid gland. Because of its propensity for invasion, pleomorphic adenoma of the parotid requires superficial parotidectomy or total parotidectomy to minimize the risk of tumor recurrence. We report a case of pleomorphic adenoma of the parotid gland with repeated recurrences. A 23-year-old male patient presented with a protruding neck mass. Six years prior to this presentation, the patient had undergone superficial parotidectomy for the removal of pleomorphic adenoma of the right parotid gland at our institution. The patient experienced recurrence at 17 months after the initial resection, which required a total parotidectomy with partial resection of the facial nerve. Pathologic examination revealed histologic findings consistent with pleomorphic adenoma across the surgical specimen from all three of the operations. The patient suffered from facial nerve paralysis, with facial expressions partially recovered over a year.