• 제목/요약/키워드: interstitial phase

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Early Detection of the Acute Exacerbation of Interstitial Pneumonia after the Surgical Resection of Lung Cancer by Planned Chest Computed Tomography

  • Oyama, Kunihiro;Kanzaki, Masato;Kondo, Mitsuko;Maeda, Hideyuki;Sakamoto, Kei;Isaka, Tamami;Tamaoki, Jun;Onuki, Takamasa
    • Journal of Chest Surgery
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    • v.50 no.3
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    • pp.177-183
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    • 2017
  • Background: To improve postoperative outcomes associated with interstitial pneumonia (IP) in patients with lung cancer, the management of the postoperative acute exacerbation of IP (PAEIP) was investigated. Methods: Patients with primary lung cancer were considered to be at risk for PAEIP (possible PAEIP) based on a preoperative evaluation. The early phase of this study was from January 2001 to December 2008, and the late phase was from January 2009 to December 2014. In the early phase, chest computed tomography (CT) was performed for patients for whom PAEIP was suspected based on their symptoms, whereas in the late phase, chest CT was routinely performed within a few days postoperatively. The numbers of possible PAEIP cases, actual PAEIP cases, and deaths within 90 days due to PAEIP were compared between both phases. Results: In the early and late phases, surgery was performed in 712 and 617 patients, 31 and 72 possible PAEIP cases were observed, nine and 12 actual PAEIP cases occurred, and the mean interval from the detection of PAEIP to starting treatment was $7.3{\pm}2.3$ and $5.0{\pm}1.8$ days, respectively. Five patients died in the early phase, and one patient died in the late phase. Significantly fewer PAEIP-related deaths were observed in the late phase (p<0.05). Conclusion: Identifying patients at risk for PAEIP by routine postoperative CT examinations led to the early diagnosis and treatment of PAEIP, resulting in the reduction of PAEIP-related mortality.

A Method and Effect for Tibial Defect Treatment Using Interstitial Low Level Laser (경골 손상 치료에서의 침습형 저출력 레이저 치료법 및 효과)

  • Lee, Sangyeob;Hwang, Donghyun;Kim, Hansung;Jung, Byungjo
    • Journal of Biomedical Engineering Research
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    • v.37 no.4
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    • pp.147-151
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    • 2016
  • Tibial defect, or fracture is very routine musculoskeletal case which brings fully uncomfortable and painful situations to patient. Moreover, it has long hospitalization period because of its risk of non-union. There are many studies using ultrasound, vibration, and laser for bone regeneration to figure out fast bone healing. Among them, Low Level Laser Therapy (LLLT) is already known that it is very easy to treat and may have positive effect for bone regeneration. However, LLLT has uncertain energy dose because of scattering and absorption of laser in tissue. In this study, we used interstitial LLLT to treat tibial defect in animal study. The Interstitial LLLT can overcome some limitations caused by laser scattering or absorption in tissue medium. The results were evaluated using u-CT which can calculate X-ray attenuation coefficient and bone volume of bone defect area. These results showed that interstitial LLLT may affect fast bone healing process in early phase.

Morphological change of Sertoli cells in the pheasant(Phasianus colchicus) testis in active and inactive phase of spermatogenesis (꿩의 정자형성기와 비형성기의 정소내 Sertoli cell의 형태적변화)

  • Yang, Hong-hyun;Paik, Young-ki;Kim, In-shik
    • Korean Journal of Veterinary Research
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    • v.34 no.1
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    • pp.9-18
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    • 1994
  • The morphological changes of Sertoli cells of the Korean native pheasant were studied in the active and inactive spermatogenic phases. Twenty-four male of the pheasants were studied in the active (April~June) and inactive(August~March) phase. These data are useful in studying the male genital organs of the Korean native pheasant. Light microscopic morphological changes of the Sertoli cells were studied on paraffin-embedded sections stained with hematoxylin-eosin stain. Ultrastructural changes of Sertoli cells were investigated of ultrathin section using electron microscope. Results are summarized as follows: During the active phase, the average diameter of seminiferous tubule was $245.33{\pm}29.93{\mu}m$ and was largely decreased by $94.50{\pm}14.10{\mu}m$, and the thickness of interstitial tissue was comparatively increased during the inactive phase. During the active phase, in the cytoplasmic process of Sertoli cell and lipid droplets appeared disperse. Well-developed smooth Endoplasmic Reticulum and microtuble were observed in the cytoplasmic process. The nuclei of Sertoli cells were adjacent to the basement membrane. The size of nuclei was reduced and nuclei of Sertoli cells were densely packed within the tubule. Few collagen fibers, fibroblast and various sizes of lipid droplets were observed in the interstitial cell of the seminiferous tubule.

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Imatinib-Mesylate Induced Interstitial Pneumonitis in Two CML Patients

  • Kim, Tae-Hoon;Kim, Byung-Gyu;Cho, Sung-Woo;Cho, Sung-Kyun;Kim, Hyun-Jung;Yuh, Young-Jin;Kim, Sung-Rok
    • Tuberculosis and Respiratory Diseases
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    • v.71 no.3
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    • pp.210-215
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    • 2011
  • Imatinib mesylate, a selective inhibitor of BCR-ABL kinase activity, has demonstrated significant clinical efficacy in the treatment of chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs). It has become the standard of treatment for these diseases. Although the toxicity profile of imatinib is superior to that of interferon or other cytotoxic agents, some adverse events including edema, gastrointestinal toxicities and hematologic toxicities are commonly observed in the patients treated by imatinib. We present two cases of imatinib induced interstitial pneumonitis during the treatment of a chronic phase of CML.

Consideration of Cement Mineral Production Amount and Microstructure Chemical Distribution of Cement Clinker Using Coal Ash and Coarse Limestone (석탄재와 조립 석회석을 적용한 시멘트 클링커의 시멘트 광물생성량과 미세구조의 화학성분 분포 고찰)

  • Dong-Woo Yoo;Sung-Ku Kwon;Min-Seok Oh;Seok-Je Lee
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.11 no.4
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    • pp.364-372
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    • 2023
  • By applying coarse-grained limestone and unprocessed coal ash as sintering raw materials for cement clinker, the microstructure and distribution of chemical components of cement clinker were compared and examined. Samples using coarse limestone as a raw material for cement clinker showed a decrease in sinterability compared to samples using reagent-grade raw materials. Samples using coal ash showed a tendency for some increase in sinterability. In samples using coarse limestone and coal ash, the formation of Belite was high at 1350 ℃. The conversion rate from Belite to Alite was high in the range of 1350~1450 ℃. Samples using coal ash showed stable formation of interstitial phase in the range of 1350 to 1450 ℃. The microstructure and chemical composition distribution of cement clinker sintered at 1350~1450 ℃ showed that all samples showed a form and composition distribution in which the calcium silicate phase and interstitial phase were clearly distinguished.

Effect of Change in Coal Ash Content on Sinterability and Phase Change of Cement Clinker (석탄재의 함량변화가 시멘트 클링커의 소성성 및 상변화에 미치는 영향)

  • Dong-Woo Yoo;Young-Jin Im;Sang-Min Choi;Sung-Ku Kwon;Seok-Je Lee
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.11 no.1
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    • pp.16-24
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    • 2023
  • Coal ash generated from thermal power plants using briquettes contains Si, Al, and Fe components. These components are the main components required for the manufacture of cement clinker. In particular, Al and Fe components form the interstitial phase of cement clinker and have an important effect on the sintering of cement clinker. In this study, a large amount of coal ash was applied as a raw material for cement clinker by content, and the mineral formation process of cement clinker to which coal ash was applied was confirmed by sintering temperature. It was confirmed that the intermediate phase was generated in the sintering temperature range of 1050 ~ 1150 ℃ in the cement clinker to which a large amount of coal ash was applied. As the content of coal ash increased, the production amount of the intermediate phase increased. The phase produced by the addition of coal ash is expected to be converted to calcium silicate phase and interstitial phase and disappear above 1350 ℃. The cement clinker applied with a large amount of coal ash at 1450 ℃ formed well-developed minerals equivalent to the standard cement clinker.

The Equilibrium Model of MoO$_3$ Containing Phases Supported in Silica

  • Lee, Do-Hyun;Ha, Jin-Wook
    • Proceedings of the KAIS Fall Conference
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    • 2001.05a
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    • pp.287-289
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    • 2001
  • The morphology of silica supported MoO$_3$ catalysts, which was prepared by impregnation of ammonium heptamolybdate with various weight loadings up to 35 wt%, was studied using x-ray diffraction. In addition to the orthorhombic phase, the behavior of the rarely studied hexagonal phase was characterized. For high loading catalysts, excess ammonium ions present in the monoclinic and triclinic precursors are capable of occupying interstitial sites of microcrystalline MoO$_3$ during moderate temperature calcinations and in doing so enhance the MoO$_3$-SiO$_2$ interaction. This results in a "well dispersed" morphology at high loadings. Sintering at high temperature is due to loss of ammonium from the oxide framework. Ammonia reimpregnation, which leads back to the well dispersed hexagonal phase, may offer a simple regeneration process for spent Mo containing catalysts.

Effects of Substrate Texture on Galvannealing Behavior of High Tensile GA Sheet Steel (고장력 합금화용융아연도금 강판의 합금화 거동에 미치는 집합조직의 영향)

  • 문만빈;신철수;오현운;남궁성;박용범
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2003.05a
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    • pp.31-32
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    • 2003
  • In the Present study, the effect of galvannealing conditions on the phase distribution of the Zn-Fe intermetallic phases in the coating layer of the galvannealed steel sheets(GA) was investigated in an interstitial free steel and two kinds of high strength steels. The composition profiles of the coating layers were analyzed using AA and EDS analysis, and the distribution of the intermetallic phases was examined with the aids of X-ray diffraction. On the basis of the pole figure and OIM analyses, it was clarified that the preferred orientation of the $\zeta$ phase depended on the development of the $\gamma$-fibre texture in the substrate.

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Effect of silicon on alloying behavior of hot-dip galvannealed steel sheets (합금화 용융아연 도금강판의 합금화 거동에 미치는 실리콘의 영향)

  • 이호종;김종상
    • Journal of the Korean institute of surface engineering
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    • v.32 no.2
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    • pp.134-143
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    • 1999
  • The effects of silicon on galvannealing behavior of interstitial-free (IF) steels were studied. The growth rate of the Fe-Zn alloy layer was retarded as silicon in the steel added. Titanium in steel strongly favors Fe-Zn reaction, in particular outburst structures, whereas silicon inhibit them. Cross-sectional and planar views of galvannealed coatings were investigated to characterize alloy phase development. A possible mechanism to explain the retardation effect of silicon is discussed in terms of concentration on surface and inhibition layer.

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Hydrodynamic coupling distance between a falling sphere and downstream wall

  • Lin, Cheng-Chuan;Huang, Hung-Tien;Yang, Fu-Ling
    • Coupled systems mechanics
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    • v.7 no.4
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    • pp.407-420
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    • 2018
  • In solid-liquid two phase flow, the knowledge of how descending solid particles affected by the presence of downstream wall is important. This work studies at what interstitial distance the velocity of a vertically descending sphere is affected by a downstream wall as a consequence of wall-modified hydrodynamic forces through a validated dynamic model. This interstitial distance-the hydrodynamic coupling distance ${\delta}_c-is$ found to decay monotonically with the approach Stokes number St which compares the particle inertia to viscous drag characterized by the quasi-steady Stokes' drag. The scaling relation ${\delta}_c-St-1$ decays monotonically as literature below the value of St equal to 10. However, the faster diminishing rate is found above the threshold value from St=10-40. Furthermore, an empirical relation of ${\delta}_c-St$ shows dependence on the drop height which clearly indicates the non-negligible effect of unsteady hydrodynamic force components, namely the added mass force and the history force. Finally, we attempt a fitting relation which embedded the particle acceleration effect in the dependence of fitting constants on the diameter-scaled drop height.