• 제목/요약/키워드: internal ratio

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Lack of Variation in Inflammatory Hematological Parameters between Benign Nodular Goiter and Papillary Thyroid Cancer

  • Yaylaci, Selcuk;Tosun, Onder;Sahin, Orhan;Genc, Ahmet Bilal;Aydin, Ercan;Demiral, Gokhan;Karahalil, Fatma;Olt, Serdar;Ergenc, Hasan;Varim, Ceyhun
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권4호
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    • pp.2321-2323
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    • 2016
  • Background: Inflammatory hematological parameters like the neutrophil/lymphocyte (N/L) ratio have been investigated in many cancer types and significant relationships found with prognosis, for example. The aim of this present study was to investigate the impact of hematological parameters notably on N/L ratio and mean platelet volume (MPV) in papillary thyroid cancer cases. Materials and Methods: A total of 79 patients who underwent a thyroidectomy operation in Findikli, Goiter Research and Treatment Center during 2011-2015 period were enrolled in the study, 41 with papillary thyroid cancer and 38 with benign goiter confirmed by pathological examination. We collected clinical and laboratory data for the patients from hospital records retrospectively. Blood samples taken at admission were assessed for parameters compared between the groups. Results: No significant differences between papillary thyroid cancer and benign goiter groups were apparent in terms of age, the N/L ratio, MPV, white blood cell count (WBC), red blood cell count (RBC), hemoglobin, hematocrit, platelet, neutrophil, lymphocyte, red blood cell distribution width (RDW) and platelet crit (PCT) levels (p>0.05). Only the level of platelet distribution width (PDW) significantly differed, being lower in the papillary cancer group (p<0.05). Conclusions: No significant relationship between papillary thyroid cancer and inflammatory hematological parameters including in particular the N/L ratio and MPV. The relevance of the PDW values remains unclear.

노인(老人) 내과환자(內科患者)의 임상통계적(臨床統計的) 고찰(考察) (Clinical Observation of the Geriatric Medical Patients)

  • 김현아;정지천;이원철
    • 대한한방내과학회지
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    • 제13권1호
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    • pp.46-60
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    • 1992
  • Clinical observation was done on 496cases of the Out-patients and 136cases of the In-patients more than 65 years of age in Department of Internal Medicine, Oriental Medical Hospital in Dong Guk Univ. from March 1991 to February 1992. The results were as follows; 1. The ratio of senile (more than 65 years of age) was 16.4% in total Out-patients, was 38.1% in total In-patients. 2. The ratio of male to female was 1:1.1 in the Out-patients, In-patients was 1.2:1. The age distribution showed the large number in the 65-69 year group, the female more than the male in 70 th's group. 3. The diagnostic distribution was noted in the Out-patients as follows, Respiratory Dis. 50.6%, Cardiovascular Dis 16.4%, Brain Neurogic Dis. 14.5%, Gastrointestinal Dis. 8.1%. in the In-patients. Brain Neurogic Dis. was 76.5%, Cardiovascular Dis was 19.8%. 4. The ratio of the season distribution in the Out-patients was as follows, spring 40.2%, winter 21.2%, summer 20.9%, in the In-patients. winter was 35.9%, autumn was 25.0%, spring was 19.9%. 5. The utilization of therapeutic clinic before coming the Oriental Medical Hospital in Dong Guk Univ, was as follows, the ratio of the Out-patients was noted a hospital or clinic was 57.1%, no-treatment 22.9%, a oriental medical hospital or clinic was 8.3%. In the admission was noted no-treatment was 38.3%, a oriental medical hospital or clinic was 35.3%. 6. The ratio of the periods from onset to Out-patients department was noted within 5days was 7.3%, over 1 year was 52.6%. In the admission was noted within 1 day was 41.9%, within 7 days was 71.8%. 7. The ratio of the therapeutic periods in the Out-patients department was noted within 10 days was 48.3%, over 60 days was 7.1%. 8. The ratio of the admission periods was noted within 10 days was 45.6%, the median of the admissio was 10.8 days. Brain Neurogic Dis's median was 20.2 days. 9. The therapeutic result was noted the case of improvement was 75.7% in the admission. 10. The ratio of the Out-patients department after discharging was 53.7%, in the case of Brain Neurogic Dis. was 60.7%.

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뇌졸중의 위험요인에 대한 환자-대조군연구 -과거병력, 생활습관, 혈청지질 및 비만요인을 중심으로- (The Case-Control Study on the Risk Factors of Stroke in Korean Adults -Past Medical History, Life-Style Factors, Serum Lipid Level, Anthropometric Indices-)

  • 고성규;정용수;박경훈;부송아
    • 대한한방내과학회지
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    • 제22권3호
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    • pp.423-430
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    • 2001
  • Objects: The purpose of this case-control study was done to examine the relationship between stroke prevalence and the anthropometric indices(body mass index(BMI), modified Broca's method(Broca's index), waist circumference(WC), waist-hip ratio(WHR)), dyslipidemia, past medical history(heart disease, hypertension, diabetes mellitus(DM)), life-style factors(smoking, drinking) in Korean adults. Methods : The study group consisted of neurologically confirmed 116 stroke patients as the case group and 116 non-stroke patients as control group. Obesity were defined as $BMI{\geq}25kg/m^2,\;Broca's\;index{\geq}30%$, WC >94cm in male and WC >80cm in female, $WHR{\geq}0.9$ in male and $WHR{\geq}0.8$ in female. Oyslipidemia were defined as total $cholesterol{\geq}200mg/dl,\;triglyceride{\geq}200mg/dl,\;HDL-cholesterol {\leq}35mg/dl,\;LDL-cholesterol{\geq}160mg/dl$. Information on life-style factors and past medical history was obtained from personal interview. The analysis of the data was done by means of chi-square test(Pearson's chi-square test, Fisher's exact test) and student t-test. Results: The results were as follow. In the study group: Hypertension had a 4:05 odds ratio, Broca's $index{\geq}30%$ had a 1.98 odds ratio, WC >94cm in male had a 2.17 odds ratio, WC >80cm in female had a 2.80 odds ratio, $WHR{\geq}0.9$ in male had a 4.66 odds ratio, $WHR{\geq}0.8$ in female had a 5.35 odds ratio, but heart disease, DM, life-style factors, serum lipid and 8MI had no direct relationship with odds ratio(nonsignificant). By student t-test, risk factors for stroke were found to be total cholesterol(p=0,025), LDL-cholesterol(p=0.013), WC(p=0.000) and WHR(p=0.000). Conclusions: This study suggests that people should be advised to control hyperlitension, hyperlipidemia and obesity since these carry a risk of stroke.

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이젝터를 적용한 이산화탄소 냉동사이클의 내부열교환기 길이에 따른 성능 변화 (Performance Variation with Length of Internal Heat Exchanger in CO2 Cooling Cycle Using an Ejector)

  • 강변;조홍현
    • 설비공학논문집
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    • 제24권2호
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    • pp.147-154
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    • 2012
  • Recently, many researchers have studied the performance of the transcritical $CO_2$ refrigeration cycle in order to improve the system efficiency. In this study, the length of IHX in the $CO_2$ ejector cycle was varied so as to evaluate the performance improvement. As a result, compressor work and cooling capacity was increased by 3% and 5% as the length of internal heat exchanger was changed from 3 m to 15 m. The best COP was appeared at internal heat exchanger length of 12 m, and it was 3.01. Besides, the length of internal heat exchanger has a big effect to pressure lift ratio and entrainment ratio in the ejector $CO_2$ cycle and it may be changed with operating conditions and system specifications.

Effect of bidirectional internal flow on fluid.structure interaction dynamics of conveying marine riser model subject to shear current

  • Chen, Zheng-Shou;Kim, Wu-Joan
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제4권1호
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    • pp.57-70
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    • 2012
  • This article presents a numerical investigation concerning the effect of two kinds of axially progressing internal flows (namely, upward and downward) on fluid.structure interaction (FSI) dynamics about a marine riser model which is subject to external shear current. The CAE technology behind the current research is a proposed FSI solution, which combines structural analysis software with CFD technology together. Efficiency validation for the CFD software was carried out first. It has been proved that the result from numerical simulations agrees well with the observation from relating model test cases in which the fluidity of internal flow is ignorable. After verifying the numerical code accuracy, simulations are conducted to study the vibration response that attributes to the internal progressive flow. It is found that the existence of internal flow does play an important role in determining the vibration mode (/dominant frequency) and the magnitude of instantaneous vibration amplitude. Since asymmetric curvature along the riser span emerges in the case of external shear current, the centrifugal and Coriolis accelerations owing to up- and downward internal progressive flows play different roles in determining the fluid.structure interaction response. The discrepancy between them becomes distinct, when the velocity ratio of internal flow against external shear current is relatively high.

동충하초(冬蟲夏草)가 hydrocortisone으로 유발시킨 양허(陽虛) 동물모형(動物模型)에서 항산화(抗酸化) 작용(作用)에 미치는 영향(影響) (Effects of Cordyceps Sinensis on Antioxidation in the Livers of Hydrocortisone Acetate-Treated Rats)

  • 이구형;민건우;윤철호;서운교;정지천;한영환;신억섭;박종혁
    • 대한한방내과학회지
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    • 제22권1호
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    • pp.63-71
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    • 2001
  • Objectives : Cordyceps Sinensis (CS) was tested for the effects of antioxidant enzymes and lipid peroxidation in the liver. Methods : We measured the changes in body weight, enzyme activity, lipid peroxide and the death rate in the hydrocortisone acetate-treated rats. Results : In vitro, CS didn't effect levels of lipid peroxide. the activities, and the ratio of type conversion of xanthine oxidase. In the hydrocortisone acetate-treated rats, lipid peroxide, the activities, the ratio of type conversion of xanthine oxidase, and the death rate all increased. But, glutathione peroxidase and superoxide dismutase decreased. In vitro, after CS was administered to hydrocortisone acetatetreated rats, the levels of lipid peroxide in the liver, and the death rate decreased. However, the activities, and the ratio of type conversion of xanthine oxidase decreased. The body weight, glutathione peroxidase, and superoxide dismutase in+creased. The effects of Sinensis Cordyceps Broth did better than the effects of Sinensis Cordyceps Mycelia. Conclusions : These results suggest that CS decrease the activities of free radical generating enzymes which form lipid peroxide and increase the activities of oxygen free radical scavenging enzymes.

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Prognostic Role of Right VentricularPulmonary Artery Coupling Assessed by TAPSE/PASP Ratio in Patients With Acute Heart Failure

  • Youngnam Bok;Ji-Yeon Kim;Jae-Hyeong Park
    • Journal of Cardiovascular Imaging
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    • 제31권4호
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    • pp.200-206
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    • 2023
  • BACKGROUND: Right ventricular (RV) dysfunction is a significant risk of major adverse cardiac events in patients with acute heart failure (AHF). In this study, we evaluated RV-pulmonary artery (PA) coupling, assessed by tricuspid annular plane systolic excursion (TAPSE)/pulmonary artery systolic pressure (PASP) and assessed its prognostic significance, in AHF patients. METHODS: We measured the TAPSE/PASP ratio and analyzed its correlations with other echocardiographic parameters. Additionally, we assessed its prognostic role in AHF patients. RESULTS: A total of 1147 patients were included in the analysis (575 men, aged 70.81 ± 13.56 years). TAPSE/PASP ratio exhibited significant correlations with left ventricular (LV) ejection fraction(r = 0.243, p < 0.001), left atrial (LA) diameter(r = -0.320, p < 0.001), left atrial global longitudinal strain (LAGLS, r = 0.496, p < 0.001), mitral E/E' ratio(r = -0.337, p < 0.001), and right ventricular fractional area change (RVFAC, r = 0.496, p < 0.001). During the median follow-up duration of 29.0 months, a total of 387 patients (33.7%) died. In the univariate analysis, PASP, TAPSE, and TAPSE/PASP ratio were significant predictors of mortality. After the multivariate analysis, TAPSE/PASP ratio remained a statistically significant parameter for all-cause mortality (hazard ratio [HR], 0.453; p = 0.037) after adjusting for other parameters. In the receiver operating curve analysis, the optimal cut-off level of TAPSE/PASP ratio for predicting mortality was 0.33 (area under the curve = 0.576, p < 0.001), with a sensitivity of 65% and a specificity of 47%. TAPSE/PASP ratio < 0.33 was associated with an increased risk of mortality after adjusting for other variables (HR, 1.306; p = 0.025). CONCLUSIONS: In AHF patients, TAPSE/PASP ratio demonstrated significant associations with RVFAC, LA diameter and LAGLS. Moreover, a decreased TAPSE/PASP ratio < 0.33 was identified as a poor prognostic factor for mortality.

ERP시스템 도입기업과 미도입기업의 회계투명성 관련 재무적 특성 (A Study on the Accounting Transparency Financial Characteristics between ERP Systems Implementation and Non Implementation Companies)

  • 최현돌;이장형
    • 한국정보시스템학회지:정보시스템연구
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    • 제14권1호
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    • pp.107-124
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    • 2005
  • ERP systems are comprehensive sorfware packages that seek to integrate the complete range of lbusiness processes and functions in order to present a heuristic perspectives of a firm from a single information and information technlogy architecture. The ERP systems have delicate internal controls with built-in devices. It is known that the delicate internal controls help to enhance the accounting transparency. We empirically investigate the relationship between the ERP systems inplementations and an accounting transparency. In order to measure the accounting transparency differences, we compare the ERP systems implementation firms with firms which did not implement the ERP systems by 6 financial ratios (accruals, net profit margin, operation cash folo to sales, total debt to equity, accounts receivable changes, assets quality). Data are collecte from 135 firms implemented the ERP systems and 135 firms non-implemented the systems (the firms listed in the Korea Stock Exchange). We analyze financial statements from 270 firms for the period 2001-2003 to ezamine the 6 financial ratios differences. The results of 810 firms analyses over the 3-year period indicate that the ERP systems implementation firms show the statistically significant differences in the accrual ratio, the net profit margin ratio, operating cash flow to sales ratio, and total debt to equity ratio from the ERP systems non-implementation firms. But there is statistically no differences between the two groups for accounts receivable changes to sales ratio and assets quality.

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쇄석과 모래 혼합다짐말뚝의 공학적 특성에 관한 연구 (A Study On The Engineering Properties of Rammed Aggregate and Sand Mixture Piers)

  • 천병식;김백영;도종남;국길근
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2009년도 춘계 학술발표회
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    • pp.119-122
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    • 2009
  • The gravel compaction pile method has been used as a soft foundation improvement method because bearing capacity and discharge capacity is excellent. But the discharge capacity decreased when the clogging was generated because the clay penetrate into a void of gravel compaction pile. Accordingly, the purpose of this study is to reduce the clogging generation in gravel compaction pile constructing in the soft ground and take a step to minimize a void of gravel compaction pile. And the proper mixing ratio was determined with the large scale direct shear test performed to get strength and permeability with mixing ratio of crushed stone and sand(100:0, 90:10, 85:15, 80:20, 75:25). As a result of the test, it was showed that internal friction angle was the highest at 85:15 mixing ratio of crushed stone and sand and we can make sure a tendency of internal friction angle's decrease when the mixing ratio of crushed stone and sand passed 15%.

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A Comparison of the Heat Transfer Performance of Thermosyphon Using a Straight Groove and a Helical Groove

  • Han Kyuil;Cho Dong-Hyun
    • Journal of Mechanical Science and Technology
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    • 제19권12호
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    • pp.2296-2302
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    • 2005
  • This study is focused on the comparison of heat transfer performance of two thermosyphons having 60 straight and helical internal grooves. Distilled water has been used as working fluid. Liquid fill charge ratio defined by the ratio of working fluid volume to total internal volume of thermosyphon, the inclination angle and operating temperature were used as experimental parameters. The heat flux and heat transfer coefficient are estimated from experimental results. The conclusions of this study may be summarized as follows; Liquid fill charge ratio, inclination angle and geometric shape of grooves were very important factors for the operation of thermosyphon. The optimum liquid fill charge ratio for the best heat flux were $30\%$. The heat transfer performance of helically grooved tube was higher than that of straight grooved tube in low inclination angle (less than $30^{\circ}$), but the results were opposite in high inclination angle (more than $30^{\circ}$). As far as optimum inclination angle concerns, range of $25^{\circ}\~30^{\circ}$ for a helically grooved tube and about $40^{\circ}$ for a straight grooved tube are suggested angles for the best results.