• Tuberculosis and Respiratory Diseases
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• 제79권3호
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• pp.184-187
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• 2016

Since IgG4-related pancreatitis was first reported in 2001, IgG4-related disease has been identified in other organs such as salivary gland, gallbladder, thyroid, retroperitoneum and kidney; but lung invasion is rare. A 63-year-old man presented with hemoptysis at the pulmonary clinic and chest computed tomography revealed about 4.1 cm irregular shaped mass with spiculated margin at the left upper lobe. Despite no elevation of serum IgG4 level, he was finally diagnosed as IgG4-related lung disease by transthoracic needle biopsy. After treatment with oral glucocorticoids, hemoptysis disappeared and the size of lung mass was decreased.

• Tuberculosis and Respiratory Diseases
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• 제68권5호
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• pp.294-297
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• 2010

Although $Taxo^{(R)}$ is one of the most successful drugs in current cancer chemotherapy against solid tumors, a major problem is hypersensitivity reactions that arises as a consequence of activation of the complement (C) system, "C activation-related pseudo-allergy". Most severe hypersenstivity reactions occur within the first few minutes of $Taxo^{(R)}$ administration, usually after the first or second dose. Here we report a case of a severe hypersensitivity reaction in a 72-year-old man undergoing $Genexol-PM^{(R)}$ infusion. Hypotension and polymorphic pruritic skin rash appeared 2 hours after the start of $Genexol-PM^{(R)}$ infusion (with an appropriate premedication). Treating with methylprednisolone, epinephrine and inotropic agents, reduced the hypotension and the skin rash disappeared. We report this case with a review of the literature.

• 대한한방내과학회지
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• 제25권3호
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• pp.582-589
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• 2004

This is a study of an admissional patient whose chief complaints were weakness and numbness in both legs, and lumbago. Diagnosis and treatment was based on overall analysis of symptoms from the point of view of muscular flaccidity due to damp-heat from an Oriental Medical point of view. 淸燥湯(Cheong Jo Tang) was administered against heat and dampness. Improvement was observed. For lack of objective criteria to evaluate improvement of these symptoms more case studies of this kind, done with screening tests and proper treatment through clinical application of the thinking of Oriental Medicine, will be needed.

• 대한한방내과학회지
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• 제25권4호
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• pp.418-425
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• 2004

The Guillain-Barre Syndrome(GBS), also called acute inflammatory demyelinating polyneuropathy and Landry's ascending paralysis, is an inflammatory disorder of the peripheral nerves - those outside the brain and spinal cord. It is characterized by the rapid onset of weakness and, often, paralysis of the legs, arms, breathing muscles and face. Finally, it leads to respiratory embarrassment and death. There is often a history of antecedent respiratory or gastrointestinal infection. Recently one patient was admitted with GBS. This patient was a 30 year-old man with quadriparesis, both facial palsy, numbness of hands and feet, and gait disturbance. After two weeks of oriental medicine and acupuncture treatment most symptoms improved. Therefore, this application of oriental medicine is reported with a plea for further investigation.

• Tuberculosis and Respiratory Diseases
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• 제78권4호
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• pp.371-374
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• 2015

Pulmonary pneumatoceles are air-filled thin-walled spaces within the lung and are rare in adult cases of pneumonia. We report the case of a 74-year-old male who was admitted with a cough and sputum production. He had been treated with oral dexamethasone since a brain tumorectomy 6 months prior. Contrast-enhanced computed tomography (CT) of the chest revealed a large pneumatocele in the right middle lobe and peripheral pneumonic consolidation. Bronchoalveolar lavage was performed; cultures identified extended-spectrum ${\beta}$-lactamase (ESBL) producing Proteus mirabilis. A 4-week course of intravenous ertapenem was administered, and the pneumatocele with pneumonia resolved on follow-up chest CT. To the best of our knowledge, this is the first reported case of pulmonary pneumatocele caused by ESBL-producing P. mirabilis associated with pneumonia.

• Tuberculosis and Respiratory Diseases
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• 제63권5호
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• pp.440-443
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• 2007

폐흡충증은 임상양상이나 방사선학적 소견이 폐결핵과 매우 유사하고 최근 우리나라에서 유병률이 낮아 조기 진단이 어렵다. 저자들은 폐결핵으로 오인된 폐흡충증 1예를 경험 하였으며 폐결핵이 의심되더라도 균이 증명되지 않거나 항결핵제 치료에 반응하지 않는 경우에 폐흡충증에 관한 병력 청취와 충란 검사 및 ELISA 검사를 통한 감별진단이 정확한 진단 및 치료에 도움이 될 것으로 사료된다.

• Tuberculosis and Respiratory Diseases
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• 제56권1호
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• pp.91-96
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• 2004

저자들은 기침을 주소로 내원한 62세 여자환자에서 폐소세포암의 진단과 함께, 경피적 세침 생검 흡입술로 확진된 반대측 유방전이 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• 대한한방내과학회지
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• 제24권2호
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• pp.171-180
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• 2003

Background : Till now Efficacy of Taeyangin medicine have not existsd in Medical Oriental medical, QSCC II(Questionnaire of sasang Constitution Classification II) can't discriminate Taeyangin is known to everybody. Objective : We have made an Effort to find out Essence of Taeyangin's Disease. Method : we have examined patient's feeling of improvement, Disease entity, Term of taking medicine, Period of ilness With eath symptoms, Comparison Taeyangin part Marks of QSSC II with Marks of improved Taeyangin questionnaire. Result : According to 43 Case of Patients Treated with Ogapijangchuk-tang, Ogapijangchuk-tang is more effective to cure Fatigue taking Headache and Dizziness than Myalgia and so on. and Item of more improved Taeyangin's constitution Question is more effective than Item of Taeyanin's constitution question in QSCC II.

• 한국임상수의학회지
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• 제38권3호
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• pp.120-126
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• 2021

Intradermal skin test (IDST) is generally considered a useful tool in identifying causal allergens in canine atopic dermatitis. Currently, multiple allergen simultaneous test (MAST), an in vitro testing method for allergen-specific immunoglobulin E, is being used as an alternative method. However, there are no reports comparing the IDST and MAST results in the same dogs. This study compared the results of both tests to evaluate the agreement and correlation between them. The sensitivity, specificity, and accuracy of the MAST were 76.2%, 64%, and 66.7%, respectively. Moderate positive predicted value (PPV, 50-75%) or high sensitivity (80-100%) were identified for indoor allergens, such as cat epithelia, house dust, and house dust mites. In contrast, high negative predicted value (NPV, 93.3-100%) and specificity (60-100%) were observed for environmental allergens and fungi. Although the agreement between IDST and MAST for all allergens was fair (κ = 0.301), that for each allergen was poor (κ < 0.01), except for birch (κ = 0.158). Spearman's rank correlation analysis revealed a low correlation between the MAST and IDST results (ρ = 0.308, p = 0.001). As compared to the IDST results, the MAST results did not identify the causative allergens sufficiently. IDST may not be performed for environmental allergens and fungi with high NPV and specificity if the MAST result is negative, but it may have to be performed for indoor allergens with moderate PPV and high sensitivity when the MAST result is positive.

• 한국임상수의학회지
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• 제38권3호
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• pp.127-134
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• 2021

Canine atopic dermatitis (CAD) is a genetically predisposed inflammatory and pruritic skin disease presenting characteristic clinical features in dogs. Despite oclacitinib and lokivetmab being commonly used, no study has compared their efficacies in CAD. This study aimed to compare the efficacy, safety, and control of CAD-associated pruritus and skin lesions between oclacitinib and lokivetmab. It also investigated whether switching to lokivetmab from oclacitinib or prednisolone had any benefits. Twenty-five client-owned dogs, newly diagnosed with CAD, were allocated to the oclacitinib (n = 20) and lokivetmab (n = 5) groups and administered oclacitinib (0.4-0.6 mg/kg orally, twice daily for 14 days, then once daily) and lokivetmab (2 mg/kg subcutaneously, every month) for 8 weeks, respectively. The switching group included five dogs previously administered with oclacitinib (n = 4) or prednisolone (n = 1) who were switched to lokivetmab directly at the start of the study. The pruritus visual analog scale (PVAS) and Canine Atopic Dermatitis Extent and Severity Index (CADESI-04) values were surveyed at weeks 0, 4, and 8. Oclacitinib and lokivetmab significantly reduced the PVAS and CADESI-04 scores. Switching from oclacitinib or prednisolone to lokivetmab maintained the severity of pruritus (4 weeks: p = 0.068; 8 weeks: p = 0.068) and dermatitis (4 weeks: p = 0.144; 8 weeks: p = 0.068) at the levels measured at baseline. Thus, both oclacitinib and lokivetmab reduced CAD-associated pruritus by a similar degree. Switching to lokivetmab maintained the severity of pruritus and dermatitis at the same level as the previous treatment.