• Title/Summary/Keyword: internal exposure

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A Case of Pulmonary Siderosis Confirmed by Bronchoalveolar Lavage and Transbronchial Lung Biopsy (기관지 폐포 세척술 및 경피적 폐 생검술로 확진된 철폐증 1례)

  • Kim, Eun A;Bang, Byoung Uk;Kim, Lucia;Ryu, Jeon Seon;Kwak, Seung Min;Lee, Hong Lyeol;Cho, Jae Hwa
    • Tuberculosis and Respiratory Diseases
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    • v.57 no.5
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    • pp.476-479
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    • 2004
  • Pulmonary siderosis is one kind of pneumoconiosis, occurs from chronic inhalation of iron or iron oxide. Inhaled iron dust is deposited in the intra-alveolar spaces, which leads to radiological changes and respiratory symptoms. It is diagnosed by iron exposure history, radiological changes, and the evidence of intra-alveolar iron deposit. We have experienced a case of pulmonary siderosis which was confirmed by bronchoalveolar lavage and transbronchial lung biopsy, so report it with a review of literature.

A New Filtering System against the Disclosure of Sensitive Internal Information (내부 중요정보 유출 방지를 위한 차단 시스템 개발)

  • Ju, Tae-kyung;Shin, Weon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.19 no.5
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    • pp.1137-1143
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    • 2015
  • Sensitive internal information has been transmitted in a variety of services of Internet environment, but almost users do not know what internal information is sent. In this paper, we intend to develop a new filtering system that continuously monitors the sensitive information in outbound network packets and notifies the internal user whether or not to expose. So we design a filtering system for sensitive information and analyze the implementation results. Thus users visually can check whether disclosure of the important information and drop the corresponding packets by the proposed system. The results of this study can help decrease cyber threats various targeting internal information of company by contributing to prevent exposure of sensitive internal information.

Impact of calcineurin inhibitors on rat glioma cells viability

  • Seong, Jeong Hun;Park, Woo Yeong;Paek, Jin Hyuk;Park, Sung Bae;Han, Seungyeup;Mun, Kyo-Cheol;Jin, Kyubok
    • Journal of Yeungnam Medical Science
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    • v.36 no.2
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    • pp.105-108
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    • 2019
  • Background: Although kidney transplantation outcomes have improved dramatically after using calcineurin inhibitors (CNIs), CNI toxicity continues to be reported and the mechanism remains uncertain. Here, we investigated the neurotoxicity of CNIs by focusing on the viability of glioma cells. Methods: Glioma cells were treated with several concentrations of CNIs for 24 hours at $37^{\circ}C$ and their cell viability was evaluated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Results: Exposure to 0, 0.25, 0.5, 2.5, 5.0, and 10.0 mM concentrations respectively showed 100%, 64.3%, 61.3%, 68.1%, 62.4%, and 68.6% cell viability for cyclosporine and 100%, 38.6%, 40.8%, 43.7%, 37.8%, and 43.0% for tacrolimus. The direct toxic effect of tacrolimus on glioma cell viability was stronger than that of cyclosporine at the same concentration. Conclusion: CNIs can cause neurological side effects by directly exerting cytotoxic effects on brain cells. Therefore, we should carefully monitor the neurologic symptoms and level of CNIs in kidney transplant patients.

A Study on the Verification and Improvement to Locate and Determine the Radioactive Contamination Using a Whole Body Counter (전신계측기를 이용한 원전종사자 방사성오염 위치확인과 내부방사능 측정개선에 관한 연구)

  • Kim, Hee-Geun;Kong, Tae-Young
    • Journal of Radiation Protection and Research
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    • v.34 no.1
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    • pp.37-42
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    • 2009
  • Whole body counters (WBCs) are used to monitor radiation workers for internal contamination of radionuclides at domestic nuclear power plants (NPPs). A WBC is a scintillation detector using sodium iodide (NaI) and provides the identification of inhaled radionuclide and the measurement of its internal radioactivity in a short time. However, it is often possible to estimate external contamination as internal contamination due to radionuclides attached to the skin of radiation workers and this leads to an excessively conservative estimation of radioactive contamination. In this study, several experiments using a WBC and the Korean humanoid phantom were performed to suggest the more systematic method of discrimination between external and internal contamination. Furthermore, a WBC geometry experiment was conducted to suggest the optimal WBC geometry in consideration of deposited areas inside the body for dominant radionuclides at NPPs. The procedure of measurement and estimation of internal radioactivity for radiation workers at NPPs was improved on the basis of experimental results. Thus, it is expected to prevent from estimating internal exposure dose conservatively owing to the application of accurate whole body counting program to NPPs.

SU-8 Mold Fabrication with Low Internal Stress and High Aspect Ratio for UV LIGA Process (고 형상비 UV LIGA 공정을 위한 낮은 내부응력의 SU-8 도금틀 제작)

  • Jang, Hyeon-Gi;Kim, Yong-Gwon
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.48 no.8
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    • pp.598-604
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    • 1999
  • This paper describes the research to minimize the film stress and maximize the aspect ratio of photoresist structure, especially about SU-8 for electroplating mold. UV LIGA process using SU-8 allows fabricating high aspect ratio polymer structures. However, it is hard to get fine patterns in the high aspect ratio structures because of high internal stress and difficulty of removing SU-8. The purpose of this paper is to setup the process condition for the obtainment of both low film stress and high aspect ratio and to find design rules that make the pattern be less dependent on stress problem. Firstly, the process of heat treatment and exposure of SU-8 are proposed. These two conditions control the amount of cross-linkage in polymer structure, which is the most important parameter of both pattern generation and remaining stress. Heat treatment is dealed with soft bake and post-exposure-bake. Temperature and time duration of each step are varied with heat treatment condition. Some test patterns are fabricated to evaluate the proposed process. Nickel electroplating is performed with the mold fabricated through the proposed process to confirm the SU-8 as a good electroplating mold.

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Status of Radiation Dose and Radioactive Contamination due to the Fukushima Accident

  • Baba, Mamoru
    • Journal of Radiation Protection and Research
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    • v.41 no.2
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    • pp.133-140
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    • 2016
  • Backgrounds: The accident at Fukushima Daiichi Nuclear Power Plant (NPP), March 2011, caused serious radioactive contamination over wide area in east Japan. Therefore, it is important to know the effect of the accident and the status of NPP. Materials and Methods: This paper provides a review on the status of radiation dose and radioactive contamination caused by the accident on the basis of publicized information. Results and Discussion: Monitoring of radiation dose and exposure dose of residents has been conducted extensively by the governments and various organizations. The effective dose of general residents due to the accident proved to be less than a mSv both for external and internal dose. The equivalent committed dose of thyroid was evaluated to be a few mSv in mean value and less than 50 mSv even for children. Monitoring of radioactivity concentration has been carried out on food ingredients, milk and tap water, and actual meal. These studies indicated the percentage of foods above the regulation standard was over 10% in 2011 but decreasing steadily with time. The internal dose due to foods proved to be tens of ${\mu}Sv$ and much less than that due to natural $^{40}K$ even in the Fukushima area and decreasing steadily, although high level concentration is still observed in wild plants, wild mushrooms, animals and some kind of fishes. Conclusion: According to extensive studies, not only the effect of the accident but also the pathway and countermeasures against radioactive contamination have been revealed, and they are applied very effectively for restoration of environment and reconstruction of the area.

The Effects of Gyumsuyukgunjun on the injured Tracheal tissue induced $SO_2$ in Rats (김수육군전(金水六君煎)이 $SO_2$에 의한 흰쥐의 호흡기조직손상(呼吸器組織損傷)에 미치는 영향(影響))

  • Lee, Sung-Yong;Park, Dong-Il
    • Korean Journal of Oriental Medicine
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    • v.2 no.1
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    • pp.226-235
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    • 1996
  • This experiment was performed in order to study the effects of Gyumsuyukgunjun on the injured tracheal tissue induced $SO_2$ in rats. Healthy adult male rats weighting about 250g were divided into 4 groups - the Normal group, the Control group, the group of Gyumsuyukgunjun administration for 5 days after $SO_2$ gas exposure (Sample I), and the group of Gyurnsuyukgunjun administration for 10 days before and for 5 days after $SO_2$ gas exposure (Sample II). The results were obtained as follows ; 1. In the trachea Control group, the lesion of the ciliated epithelium was severe and the mucus secretion of the respiratory tract was increased significantly. 2. In the trachea of Sample I group, the lesion of the ciliated epithelium and the mucus secretion of the respiratory tract were decreased compared with Control group. 3. In the trachea of Sample II group, the lesion of the ciliated epithelium and the mucus secretion of the respiratory tract were decreased compared with Control and Sample I group. According to the above results, Gyumsuyukgnjun has significant effects on the injuried tracheal tissue caused by $SO_2$ in rats.

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Partial Discharge Diagnosis of Thermal Degradated PVC Cable (열열화된 PVC 케이블의 부분방전 진단)

  • Song, Ki-Tae;Lee, Sung-Ill
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.24 no.3
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    • pp.208-214
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    • 2011
  • In this thesis, the partial discharge according to applied voltage and variations of cross-sectional area and length of the conductor related to general condition for using cable was measured in order to study degradation diagnosis for 2-Core cable of the PVC insulator used in industrial fields for other safety installations. Also the thermal degradation conditions under various installation circumstances of cables were studied by assuming degradation conditions with each different degradation rate (50%, 67%, 100%) such as variation in degradated temperature, thermal exposure time, normal state, partially degradated state and overall degradated state for thermal degradation diagnosis. The quantity of electric discharge (V-Q) according to applied voltage was measured for measurement of inception voltage and extinction voltage. The quantity of electric discharge and the number of electric discharge (Q-N) were measured with applied voltage kept constantly. In addition, pictures were taken using SEM (scanning electron microscope) to compare the surface of external insulator to degradated state of internal insulator according to thermal degradation temperature and also compare the surface of external insulator to degradated surface state of internal insulator according exposure time of cables to thermal stress.

The Relation between Exposure to Environmental Tobacco Smoke and the Quantity of Cotinine in the Urine of School Children in Taif City, Saudi Arabia

  • Desouky, Dalia El Sayed;Elnemr, Gamal;Alnawawy, Ali;Taha, Azza Ali
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.139-145
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    • 2016
  • Environmental tobacco smoke (ETS) is a major public health problem for all ages. Despite the high prevalence of smoking among the Saudi population, there is limited information about levels of urinary cotinine in Saudi children exposed to SHS. The aim of the study was to assess the exposure of schoolchildren to ETS, and measure their urinary cotinine levels. Multistage cluster sampling was carried out, where schoolchildren from 4 schools were randomly chosen from primary schools in Taif city. A questionnaire including questions on SHS exposure and smoking rules in the residence were sent to students parents/guardians. Urine samples were taken and analyzed for total cotinine using chemiluminescent immunoassay. Of the studied children, 38.4% had a smoking father, 61.8%, 41.2% and 49.3% of them were exposed to ETS indoors, outdoors and both indoors and outdoors respectively. The mean urinary cotinine was significantly higher among children exposed to ETS compared to unexposed children. Urinary cotinine levels in children with both indoor and outdoor exposure was significantly higher compared with its level in children with single exposure. A significant positive correlation was found between urinary cotinine concentrations and the number of cigarette packs smoked by parents, and the number of smokers in the residence. The mean urinary cotinine level was significantly higher in children who reported no smoking rules at the residence.. The study revealed a high exposure of Saudi children to ETS. An antismoking media awareness campaign on the harmful effects of ETS should be carried out, in addition to family counseling programs targeted to parents to protect their children from ETS.