• Title/Summary/Keyword: internal diseases

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Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 2. Idiopathic Pulmonary Fibrosis

  • Lee, Sang Hoon;Yeo, Yoomi;Kim, Tae-Hyung;Lee, Hong Lyeol;Lee, Jin Hwa;Park, Yong Bum;Park, Jong Sun;Kim, Yee Hyung;Song, Jin Woo;Jhun, Byung Woo;Kim, Hyun Jung;Park, Jinkyeong;Uh, Soo-Taek;Kim, Young Whan;Kim, Dong Soon;Park, Moo Suk;Korean Interstitial Lung Diseases Study Group
    • Tuberculosis and Respiratory Diseases
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    • v.82 no.2
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    • pp.102-117
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    • 2019
  • Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing interstitial pneumonia, which presents with a progressive worsening dyspnea, and thus a poor outcome. The members of the Korean Academy of Tuberculosis and Respiratory Diseases as well as the participating members of the Korea Interstitial Lung Disease Study Group drafted this clinical practice guideline for IPF management. This guideline includes a wide range of topics, including the epidemiology, pathogenesis, risk factors, clinical features, diagnosis, treatment, prognosis, and acute exacerbation of IPF in Korea. Additionally, we suggested the PICO for the use of pirfenidone and nintendanib and for lung transplantation for the treatment of patients with IPF through a systemic literature review using experts' help in conducting a meta-analysis. We recommend this guideline to physicians, other health care professionals, and government personnel in Korea, to facilitate the treatment of patients with IPF.

Pulmonary Foreign Body Granulomatosis in Dental Technician

  • Chung, Sung Jun;Koo, Gun Woo;Park, Dong Won;Kwak, Hyun Jung;Yhi, Ji Young;Moon, Ji-Yong;Kim, Sang-Heon;Sohn, Jang Won;Yoon, Ho Joo;Shin, Dong Ho;Park, Sung Soo;Pyo, Ju Yeon;Oh, Young-Ha;Kim, Tae-Hyung
    • Tuberculosis and Respiratory Diseases
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    • v.78 no.4
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    • pp.445-449
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    • 2015
  • Occupational lung diseases are caused by several toxic substances including heavy metals; however, the exact pathologic mechanisms remain unknown. In the workplace, dental technicians are often exposed to heavy metals such as cobalt, nickel, or beryllium and occasionally develop occupational lung diseases. We described a case of occupational lung disease in a patient who was employed as a dental technician for over a decade. A 31-year-old, non-smoking woman presented with productive cough and shortness of breath of several weeks duration. Chest computed tomography revealed a large number of scattered, bilateral small pulmonary nodules throughout the lung field, and multiple mediastinal lymph nodes enlargement. Percutaneous needle biopsy showed multifocal small granulomas with foreign body type giant cells suggestive of heavy metals inhalation. The patient's condition improved on simple avoidance strategy for several months. This case highlighted the importance of proper workplace safety.

A Case Report on the Use of Heart Rate Variability and the Treatment Effect of Bunshimgi-eum on Autonomic Dysfunction After Cerebral Infarction (뇌경색 후 발생한 자율신경 장애에 대해 심박변이도로 살펴본 분심기음의 효과 증례보고 1례)

  • Jun-seok Kim;Ji-hyeon Kang;Seo-hyun Kim;Chae-eun Kim;Na-yeon Kim;Woo-seok Jang
    • The Journal of Internal Korean Medicine
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    • v.44 no.1
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    • pp.66-76
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    • 2023
  • Background: The aim of this study is to investigate the use of heart rate variability on a stroke patient with autonomic dysfunction and the effectiveness of Bunshimgi-eum. Case report: The patient showed autonomic dysfunction, including chest discomfort, 煩燥 (sweating, anxiety, insomnia, nausea, lightheadedness), and abdomen discomfort (dyspepsia, heartburn) after ischemic stroke. She was treated with a herbal medicine (Bunshimgi-eum) through complex Korean medicine treatment. The effect was evaluated using heart rate variability (HRV), Mini-Mental State Examination-DS (MMSE-DS), mean pulse rate, and subjective percentage of symptoms. After treatment, the HRV score, MMSE-DS score, and subjective percentage of symptoms improved, and the pulse rate decreased from the upper boundary value. Discussion: The results suggest that HRV may be useful in evaluating stroke patients with autonomic dysfunction and that Bunshimgi-eum is suitable for treatment.

A Case with Single Cavitary Nodule in Right Upper Lung (우상부의 공동성 폐 병변)

  • Choi, Jin-Won;Park, Ik-Soo;Choi, Wan-Young;Shin, Dong-Ho;Park, Sung-Soo;Lee, Jung-Hee;Jeon, Suck-Chul;Park, Moon-Hyang;Lee, Jung-Dal
    • Tuberculosis and Respiratory Diseases
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    • v.39 no.2
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    • pp.199-204
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    • 1992
  • A 46 years old male showed radiologically a single cavitary nodular lesion in right upper lung, which extended to the regional chest wall. This finding has to be made into differential diagnosis of numerous pulmonary diseases including infections such as mycobacterial, fungal or bacterial, granulomatous diseases, and neoplasms. For the definite diagnosis, fine needle aspiration biopsy guided by biplane fluoroscopy was performed. The aspirates contained several sulfur granules, in the center of which many gram positive, filamentous organisms were compactly intermingled. Such a findings was compatible with pulmonary actinomycosis. Now the lesions is cleared out by medical treatment with amoxicillin for 3 months.

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Extremely Increased Serum Carbohydrate Antigen 19-9 Levels Caused by New or Resistant Infections to Previous Antibiotics in Chronic Lung Diseases

  • Shin, Ji Young;Yoo, Su Jin;Park, Bo Mi;Jung, Sung Su;Kim, Ju Ock;Lee, Jeong Eun
    • Tuberculosis and Respiratory Diseases
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    • v.75 no.3
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    • pp.125-127
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    • 2013
  • In this paper, we describe 72-year-old female patient without evidence of malignant disease presented with significantly elevated serum carbohydrate antigen (CA) 19-9 levels by respiratory infections. She was diagnosed with respiratory infections due to Mycobacterium avium complex and Pseudomonas aeruginosa. The serum CA 19-9 levels remarkably increased (1,453-5,300 U/mL; reference range, <37 U/mL) by respiratory infection and abruptly decreased (357-534 U/mL) whenever infection was controlled by specific treatments. This case suggests that serum CA 19-9 levels may be used as a diagnostic marker to indicate new or resistant infections to previous antibiotics in chronic lung diseases without significant changes in chest X-ray findings.

Bilateral Medial Medullary Infarction (Dejerene Syndrome) Patient Suffering from Quadriplegia Treated by Korean Traditional Medicine: a Case Report

  • Lee, Yoo-na;An, Yu-min;Baek, Kyungmin;Jang, Woo-seok
    • The Journal of Internal Korean Medicine
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    • v.41 no.5
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    • pp.902-910
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    • 2020
  • Medial medullary infarction, with representing symptoms of hemiparesis, lingual palsy, and sensory defect, usually has a bad prognosis. The present case is unusual as the patient had a bilateral infarction, and little information is available for bilateral cases. We treated a patient diagnosed with bilateral medial medullary infarction with the symptoms of quadriplegia, lingual palsy, dyspnea, dysphagia, spastic pain, and loss of proprioception. After 126 days of traditional Korean medicine treatment, the patient showed increased muscle power, sensory recovery, reduced spastic pain, and alleviation of dysphagia and dyspnea. This report indicates that traditional Korean medicine could be an effective treatment of the sequelae of medullary infarctions.

A Case Report of Chronic Chemotherapy-Induced Peripheral Neuropathy Treated by Korean Traditional Medicine (항암화학요법으로 유발된 만성 말초신경병증 환자의 한의학적 치험 1례 : 2년 이상 지속된 항암화학요법 유발 말초신경병증 치험)

  • An, Yu-min;Lee, Yoo-Na;Baek, Kyungmin;Jang, Woo-Seok
    • The Journal of Internal Korean Medicine
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    • v.41 no.5
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    • pp.892-901
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    • 2020
  • Objective: This study reports the effect of Korean traditional medicine on persistent chemotherapy-induced peripheral neuropathy (CIPN). Methods: The patient was treated with Korean traditional medicine that included acupuncture, moxibustion, and herbal medicine. The effectiveness of the treatment was evaluated by the Quality of Life Questionnaire-Core 30 (QLQ-C30), the Quality of Life Questionnaire Chemotherapy-Induced Peripheral Neuropathy (QLQ-CIPN20), the Medicinae Doctor Anderson Symptom Inventory (MDASI), and a numeral rating scale (NRS). We also used the Beck Depression Inventory (BDI) to evaluate the patient's mood change after relieving the paresthesia. Results: After treatment, the symptoms were improved. Paresthesia decreased 80%p after Korean medicine treatment. Conclusions: According to this study, Korean traditional medicine can be an effective treatment for paresthesia in patients suffering from CIPN over 2 years.

A Case of Pasteurella Multocida Pleural Empyema (Pasteurella Multocida 농흉 1예)

  • Lee, Dong-Yeub;Baek, Seung-Min;Seo, Hyang-Eun;Sohn, Kyung-Rak;Song, Do-Yong;Chung, Byung-Chun;Lee, Byung-Ki;Kim, Won-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.49 no.1
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    • pp.111-116
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    • 2000
  • Pasteurella multocida, a Gram-negative coccobacillus, is part of the normal oral flora of many types of animals, including domestic dogs and cats. It is the etiologic agent of a variety of infectious diseases, such as hemorrhagic septicemia in cattle or fowl cholera in chicken. Although this is a primary pathogen in the animal world, infection due to Pasteurella multocida in man has been described with increasing frequency recently. The majority of individuals with Pasteurella multocida pulmonary infection possess some underlying pulmonary diseases, most commonly bronchiectasis or COPD. With a review of literature, We report a young man who developed the empyema caused by Pasteurella multocida.

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