• Journal of Yeungnam Medical Science
• /
• v.30 no.1
• /
• pp.25-30
• /
• 2013

Hyponatremia, the most common electrolyte disorder, has been rarely reported as causing rhabdomyolysis. Osmotic demyelination syndrome (ODS), a demyelinating disease of the central pons and/or other areas of the brain, is infrequently reported as associated with rapid correction of hyponatremia. This paper reports a case of ODS after correction of severe hyponatremia complicated by rhabdomyolysis. A 47-year-old female with a history of chronic alcoholism presented herself at the hospital with altered consciousness after three days of nausea and vomiting. She was on a thiazide diuretic for essential hypertension. Her blood tests upon her hospital admission showed hyponatremia ($Na^+$ 98 mEq/L), hypokalemia ($K^+$ 3.0 mEq/L), and elevation of her serum creatine phosphokinase (3,370 IU/L) with an increase in her serum myoglobin level 11,267 ng/mL). She was treated with intravenous fluid therapy that included isotonic and hypertonic salines along with potassium chloride. She became more alert, and her neurological condition gradually improved after the first five days of her therapy. On the ninth day after her admission, she developed progressive quadiaresis associated with dysarthria, dysphagia, and dystonia despite the resolution of her hyponatremia. Magnetic resonance imaging of her brain on 16th day revealed symmetrical areas of signal hyperintensity in her central pons, basal ganglia, and precentral gyrus in T2-weighted images, which are consistent with ODS. Her neurological symptoms steadily improved after six weeks with only supportive treatment and rehabilitation.

• Journal of Chest Surgery
• /
• v.33 no.4
• /
• pp.277-284
• /
• 2000

Background: Coronary artery bypases grafting in the old aged is associated with high mortality and morbidity, and it is difficult to perform if the coronary artery is diffusely disease. Recently it has been known that platelet derived growth factor(PDGF), especially PDGF-BB, stimulates angiogenesis. Material and Method: New Zealand white rabbit were used. In an attempt to achieve effevtive cardiac revasculatrization without vascular anastmosis, we divided into three groups(group I : Left anterior descending artery(LAD) was occluded by ligature, group II : Bilateral internal mammary vascular pedicles were dissected and implanted into myocardium, group III : The vascular pedicles were implanted into myocardium and PDGF-BB was injected into the myocardial tissue). Two weeks after IMA implantation, the proximal region of implanted LAD was ligated. Four days after LAD ligation angiogram, triphenyl tetrazolium chloride(TTD) staining and hematoxylin eosin staining were performed. Result: 1. Survival rate in group II was significantly higher than that in group I (P<0.05), and survival rate in group III was signficantly higher than that in group II(53% vs 93%, P<0.01). 2. There were significant differences in the ratio of area of necrosis to area at risk between group I and group II, and between group II and group III (P<0.01). 3. Microangiogram for angiogenic response revealed wide area of extensive revascularization with patent vessels in group III. 4. Histologic findings of three groups showed that polymorphonuclear leukocyte infiltration was minimal in group II and none in group III. Conclusion: PDGF-BB can establish functinal cardiac revasculatization through systemic vessels implanted directly into the myocardium.

• The Journal of Internal Korean Medicine
• /
• v.37 no.4
• /
• pp.591-600
• /
• 2016

Objective: This study aimed to examine the relaxation effects and underlying mechanisms of Cynomorii herba (CH) extract in isolated rabbit corpus cavernous tissues.Methods: We experimented with CH extract (0.01-3.0 mg/mL). Nω-nitro-L-arginine (L-NNA) was experimented before the CH extract to contracted strips induced by phenylephrine (PE, 1 μM)and compared with nonexperimented. In addition, we experimented with calcium chloride (Ca²⁺, 1 mM) after pretreatment of the CH extract in Ca²⁺-free Krebs-Ringer solution to contracted strips induced by PE. The cell viability and nitric oxide (NO) concentration of human umbilical vein endothelial cells (HUVECs) were measured by an methylthiazol-2-yl-2, 5-diphenyl tetrazoliumbromide (MTT) assay and Griess reagent system. The ratio of smooth muscles to collagen fibers, in addition to eNOS- and PDE-5-positive reactions, was examined by histochemical and immunohistochemical staining.Results: The CH extract significantly induced the relaxation of the cavernous strips, and the pretreatment with L-NNA inhibited CH extract-induced relaxation. The L-NNA pretreatment reduced the increased contraction induced by the addition of Ca²⁺in Ca²⁺-free solution. Furthermore, the NO concentration of the HUVECs increased. When the CH extract was applied to the corpus cavernosum of the penis (CCP) of Sprague Dawley rats, the ratio of smooth muscles to collagen fibers by PE and the formation of eNOS around the helicine artery increased. However, the CH extract treatment decreased PDE-5 positive reactions.Conclusions: These results show that the relaxation effects induced by the CH extract are associated with the suppression of the influx of extracellular Ca²⁺ via the production of NO and eNOS and inhibition of PDE-5.

• The Korean Journal of Nuclear Medicine
• /
• v.24 no.1
• /
• pp.133-137
• /
• 1990

The general use of a number of $^{99m}Tc-labelled$ compounds makes the need for good routine quality control procedures, especially the labelling efficiency measurements. The purpose of these study were to measure the labelling efficiency of $^{99m}Tc-labelled$ MDP, DTPA, Tin colloid, and Antimony sulfide colloid using miniaturized paper and instant thin layer chromatography. The chromatographic systems include whatman 3 MM paper and acetone, Gelman ITLC-SG and 0.9% sodium chloride. The chromatographic strips are miniaturized $(1\times10\;cm)$, marked and numbered. Labelling efficiencies of $^{99m}Tc-labelled$ DTPA and Tin colloid were above 98.0%. $^{99m}Tc-labelled$ Antimony sulfide colloid was 90.0%. And labelling efficiency of $^{99m}Tc-labelled$ MDP was 89.0% Coefficient variance of $^{99m}Tc-labelled$ MDP, DTPA, Tin colloid, and Antimony sulfide colloid were 5.14%, 2.06%, 1.82% and 4.90%, respectively. We found that this miniaturized chromatographic quality control was simple and reliable.

• Journal of the Society of Disaster Information
• /
• v.4 no.1
• /
• pp.138-152
• /
• 2008

The most important factor in the maintenance of chemical industry facilities is related with deterioration and corrosion. Leakage of hazardous materials is likely to occur because the confirmation and maintenance of bottom plates are very difficult while the bottom corrosion of the massive hazmat-storage facilities is most dangerous especially. As a result of the analysis of the corrosion locations, areas, usage condition of 287 hazmat-storage tanks on this syudy, it is concluded that the main external corrosion factors are the inflow of moisture and the materials inducing corrosion in the air such as sodium chloride and the main internal corrosion factors are corrosion react caused by stay of seawater, sulfur and moisture in hazmat for a long time without appropriate discharges. It is anticipated that the corrosion of bottom plates can be restrained effectively by establishing the proper measures for the each corrosion cause.

• Elastomers and Composites
• /
• v.11 no.2
• /
• pp.113-121
• /
• 1976

Fundamental and specific properties of the tennis ball on rubber ball body are surveyed to match the quality of the tennis ball now on applied in the tennis game, 1. Much dose of filler of non-crystalline or flat form applied to rubber compounding than general procedure and over vulcanization is found excellent in the resistant to gas permeability. 2. Flat curing improved characteristics of the ball on the homogenous rebounds when applied on the specified concrete surface. 3. Satisfactory adhesive power is found with Desmodur R and standard rubber recipe in case of applying on the under-vulcanizate of half sphere. 4. The stable gas-generating compounds of sodiun nitrate, ammonium chloride, water and sodium carbonate, anhydorus help controlling of optimum internal over-pressure in the tall.

• Journal of the Korean Society of Safety
• /
• v.19 no.2
• /
• pp.98-103
• /
• 2004

Shotcrete needs the enough durability without deterioration for life time. But shotcrete is being deteriorated according to aging like concrete by internal causes whithin itself and by external causes which can be physical, chemical, or mechanical. Durable shotcrete can be made by incresing the cement content, adding chemical and mineral admixtures and so on. So, in this study, chloride ion penetration test, freeze and thaw test, neutralization test were conducted to examine the durability characteristice of shotcrete with mineral admixtures such as silica fume, blast-furnace slag and fly ash. These results indicate that shotcrete with silica fume is durable. Therefore, the present study provides a firm base to make high performance shtcrete.

• Journal of the Korean Society of Safety
• /
• v.31 no.4
• /
• pp.82-89
• /
• 2016

In this paper, various of experiments were performed for checking the usefulness of Pozzolan Inorganic Polymer(PIP) Waterproof Admixture. The results of the experiment enabled to set the optimum mixture ratio of PIP waterproof admixture as 3.5%. Then, the test specimen mixed with PIP waterproof admixture was produced and consider whether meeting the quality standard of waterproofing admixture for concrete (KS F 4926) From the results, all the items such as mechanical properties and durability were meet the quality standard of KS. The PIP waterproof admixture concrete shows the high resistance of absorption, permeability and chloride ion penetration thanks to its internal components such as siliceous powder, zinc stearate and dispersive polymer.

• Corrosion Science and Technology
• /
• v.16 no.5
• /
• pp.227-234
• /
• 2017

Reference electrodes are generally implemented for the purpose of monitoring the cathodic protection potentials of buried or immersed metallic structures. In the market, many types of reference electrodes are available for this purpose, such as saturated calomel, silver/silver chloride and copper/copper sulfate. These electrodes contain a porous ceramic junction plate situated in the cylindrical body bottom to permit ionic flux between the internal electrolyte (of the reference electrode) and the external electrolyte. In this work, the copper/copper sulfate reference electrode was modified by replacing the porous ceramic junction plate for a metallic platinum wire. The main purpose of this modification was to avoid the ion copper transport from coming from the inner reference electrode solution into the surrounding electrolyte, and to mitigate the copper plating on the coupon surfaces. Lab tests were performed in order to compare the performance of the two mentioned reference electrodes. We verified that the experimental errors associated with the measurements conducted with developed reference electrode would be negligible, as the platinum surface area exposed to the surrounding electrolyte and/or to the reference electrolyte are maintained as small as possible.

• Proceedings of the Korea Concrete Institute Conference
• /
• 2006.05b
• /
• pp.169-172
• /
• 2006

The IIA structures exposed to marine environment is subject to many different types of potential attack. The physical attack due to drying and wetting would increase the internal stress of concrete. The chemical attack resulting from the diffusion of ions$(Cl^-,SO_4^{2-},Mg^+)$ from seawater through the pores in concrete. Therefore the sea water resistance of concrete must be considered when it is used for structure in the ocean. The objective of this study is to evaluate chloride diffusion and corrosion characteristics of concrete when using the various concrete materials under marine environment. After 5 years of exposure, concrete incorporating 40% blast-furnace slag as replacement for type I cement with low w/c ratio of 0.42 and using the inhibitor shows excellent performance.