• International Journal of Aeronautical and Space Sciences
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• 제18권1호
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• pp.1-7
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• 2017

To predict the transonic buffet onset for a supercritical airfoil with shock-boundary layer interactions, a practical steady approach has been proposed. In this study, it is assumed that the airfoil flow is steady even when buffet onset occurs. Steady Navier-Stokes computations are performed on the supercritical airfoil. Using the aerodynamic parameters calculated from Navier-Stokes solver, various steady approaches for predicting buffet onset are discussed. Among the various steady approaches considered in this study, Thomas' criterion based on Navier-Stokes computation has shown to be the most appropriate indicator of identifying the buffet onset for a supercritical airfoil with shock-boundary layer interactions. Good agreements have been obtained compared with the results of unsteady transonic wind tunnel tests. The present method is shown to be reliable and useful for transonic buffet onset for a supercritical airfoil with shock-boundary layer interactions in terms of practical engineering viewpoint.

• 셀메드
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• 제4권3호
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• pp.17.1-17.8
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• 2014

Herbal remedies are commonly used by patients worldwide. Because these herbal preparations share the same metabolic and transport proteins with prescribed medicines, the potential for a drug-herb interaction is substantial and is an issue of significant concern. This review paper summarizes drug-herb interactions involving inhibition or induction of cytochrome P450 enzymes, drug transporters as well as modulation of drug pharmacodynamics. An increasing number of in vitro and animal studies, case reports and clinical trials evaluating such interactions have been reported, and implications of these studies are discussed in this review. The most commonly implicated drugs in the interaction include anticoagulants, antiplatelets, immunosuppressants, anti-neoplastics, protease inhibitors, and some antidepressants. Pharmacokinetic and/or pharmacodynamic interactions of five commonly used herbal remedies (danshen, garlic, Ginkgo biloba, ginseng, and St John's wort) with these drugs are presented, with focus of discussion being the potentials for interaction, their mechanisms and clinical implications. There is a necessity for adequate pharmacovigilance to be carried out in minimizing unanticipated but often preventable drug-herb interactions.

• 한국재료학회:학술대회논문집
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• 한국재료학회 2011년도 춘계학술발표대회
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• pp.6.2-6.2
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• 2011

Block copolymer (BCP) self-assembly in a film geometry has recently been the focus of increased research interest due to their potential use as templates and scaffolds for the fabrication of nanostructured materials. The phase behavior in a thin film geometry that confines polymer chains to the interfaces will be influenced by the interfacial interactions at substrate/polymer and polymer/air and the commensurability between the equilibrium period (L0) of the BCP and the total film thickness. We investigated the phase transitions for the films of block copolymers (BCPs) on the modified surface, like the order-to-disorder transition (ODT) by in-situ grazing incidence small angle x-ray scattering (GISAXS) and transmission electron microscopy (TEM). The selective interactions on the surface by a PS-grafted substrate provide the preferential interactions with the PS component of the block, while a random copolymer (PS-r-PMMA) grafted substrate do the balanced interfacial interactions on the surface. The thickness dependence of order-to-disorder behavior for BCP films will be discussed in terms of the surface interactions.

• 아동학회지
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• 제13권2호
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• pp.33-51
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• 1992

The purpose of this study was to investigate activities of kindergarteners in the mathematics corner. The study included an analysis of children's interactions with mathematics materials and of children's peer interactions during mathematics activities. The subjects were 47 children aged three to four and 72 children aged four to five from four classes of two kindergartens in Kwangju. Children's math activities during free play sessions were observed and audiotaped. The data were coded by the categories of children's peer interactions and types of mathematics manipulations. The characteristics of children's peer interactions and materials frequently selected by the subjects were identified. The results indicated that (1) most of the math materials were for passive manipulation that require children to respond according to predetermined conditions like the rules of games, but (2) the materials that children liked to play with were active manipulative materials that require diversity and flexibility of children's thinking and allow several choices for solutions, and (3) children's peer interactions during math activities were categorized into unilateral and reciprocal/collaborative peer interaction type.

• 한국수학교육학회지시리즈D:수학교육연구
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• 제17권3호
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• pp.181-198
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• 2013

Teaching and learning mathematics in a classroom setting is based on the interactions between the teacher and her students. Using classroom observations and interviews of students and the teacher, this research examines a first-year teacher and her students' interactions in the mathematics classroom. In this mathematics classroom, teacher and students interaction had inconsistency between mathematical topics and non-mathematical topics. For non-mathematical topics, their interactions were very active but for mathematical topics their interactions were very limited. This paper ends with raising questions for future research and calling for the opportunities for first-year teachers to reflect on their interactions with their students, in particular about mathematical topics.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2002년도 학술대회지
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• pp.159-160
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• 2002

New S-shaped aeroelastic mesoflaps are utilized to control normal shock/boundary-layer interactions. New generation of the mesoflaps is designed f3r a better rigidness and a good flow uniformity across the ulteractions. ,Major advantages of the mesoflap system can be a better total pressure recovery downstream of the interactions due to the lambda shock structure over the flap system, and a rehabilitation of the thickened boundary layer due to bleeding through a cavity underneath the flap system. Skin friction has been measured downstream of the interactions, using the laser interferometer skin friction (LISF) meter, which optically detects the rate of thinning of an oil film applied to the test surface. Various flap-thicknesses of the S-shaped mesoflap arrays are tested, and the results are compared to the solid-wall reference case. Overall, not much difference in the level of skin friction is noticed for the S-shaped flap arrays of various thicknesses, and its level is lower than the skin friction downstream of the solid-wall interaction

• 한국발생생물학회지:발생과생식
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• 제23권4호
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• pp.305-311
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• 2019

Small intestine has a structure called villi that increases the mucosal surface area for nutrient absorption. Intricate and tight epithelial-mesenchymal interactions are required for villi development. These interactions are regulated by signaling molecules, physical forces, and epithelial deformation. Signaling molecules include hedgehog (Hh), bone morphogenetic protein (BMP) and Wnt ligands. The Hh ligand is expressed from the epithelium and binds to the underlying mesenchymal cells, resulting in aggregation into mesenchymal clusters. The clusters express BMP and Wnt ligands to control its size and spacing between clusters. The clusters then form villi. Despite the fact that the villi formation is studied extensively, we do not have a complete understanding. In addition, the recent study shows there is a great relationship between the overexpression of the Hh signal and development of cancer in the gastrointestinal tract. Therefore, signaling between epithelial and mesenchymal cells and their physical interactions will be discussed on this review.

• The Plant Pathology Journal
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• 제29권2호
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• pp.136-143
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• 2013

Microbial communities that are associated with plant roots are highly diverse and harbor tens of thousands of species. This so-called microbiome controls plant health through several mechanisms including the suppression of infectious diseases, which is especially prominent in disease suppressive soils. The mechanisms implicated in disease suppression include competition for nutrients, antibiosis, and induced systemic resistance (ISR). For many biological control agents ISR has been recognized as the mechanism that at least partly explains disease suppression. Implications of ISR on recruitment and functioning of the rhizosphere microbiome are discussed.

• 아동학회지
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• 제18권1호
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• pp.23-38
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• 1997

This study investigated the difference between infant verbal and nonverbal interactions with a partner (teacher or peer). The subjects were 20 two-year-old infants 00 boys and 10 girls, mean age 31.3 months). Verbal and nonverbal interactions were videotaped during one hour of indoor free play per child in the Center. In verbal interaction, (1) boys spoke to themselves more than girls did, and (2) girls gave orders (imperatives, requests, and prohibitions) to peers and teachers more than boys did. In non-verbal interactions, (1) girls nodded to teachers more than boys did, (2) boys came closer to peers more than girls did, and (3) girls refused by gestures to peers more than boys did. In conclusion, the majority of the boys could be classified as peer-oriented and physically active in their interactions.

• 한국수산과학회지
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• 제49권6호
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• pp.815-822
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• 2016

The cationic biopolymer chitosan has several applications in medicine. Chitosan is the deacetylated derivative of chitin, the second most abundant naturally occurring polymer. Recent studies have investigated the relationship between chitosan and antibacterial activity. However, the molecular interactions and mechanisms have not been detailed. This study used molecular dynamics simulations to study interactions between chitosan and anionic bacterial membranes (POPE-POPG) and electrically neutral non-bacterial membranes (POPC). We calculated the free energy using umbrella sampling to compare the interactions between membranes and chitosan in different protonation states. Fully protonated chitosan interacted most strongly with the bacterial membranes, but weakly with non-bacterial membranes. These results suggest that electrostatic interactions are the main mechanism of the antibacterial activity of chitosan, and they provide insights into the design of novel antibacterial and antimicrobial agents.