• Title/Summary/Keyword: inter-chain flexibility

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The Relationship Between Supply Chain Competences, Capability, and Fim Performance: A Supply Chain Agility (공급사슬 역량과 능력 그리고 기업성과 간의 관계: 공급사슬의 민첩성을 중심으로)

  • Kang, Sung-Bae
    • Knowledge Management Research
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    • v.13 no.2
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    • pp.95-109
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    • 2012
  • Changing customer expectation, global competition, and technological requirements force firms to develop agile supply chain capabilities sustaining competitive advantage and business success. To respond, firms are seeking to enhance supply chain agility across the inter-organizational, this study explores the relationship between supply chain competence and supply chain agility on firm performance. The research reviews literature on supply chain capability and classifies capability into two categories as competence and capability based on resource based view and dynamic capabilities. It describes a framework to explore the relationships among supply chain competence (IT flexibility, supply chain flexibility, shared value), supply chain capability (supply chain agility), and firm performance (supply chain performance). The purpose of this study is to find the determinants of supply chain agility and improving firm performance in the perspective of vendor companies. The results indicate strong, positive, and direct relationships between supply chain competence and supply chain agility. Supply chain agility have significant relationships with firm performance. Implication for future research and practice are offered.

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Solution Structure of an Active Mini-Proinsulin, M2PI: Inter-chain Flexibility is Crucial for Insulin Activity

  • Cho, Yoon-Sang;Chang, Seung-Gu;Choi, Ki-Doo;Shin, Hang-Cheol;Ahn, Byung-Yoon;Kim, Key-Sun
    • BMB Reports
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    • v.33 no.2
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    • pp.120-125
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    • 2000
  • M2PI is an active single chain mini-proinsulin with a 9-residue linker containing the turn-forming sequence 'YPGDV' between the B- and A-chains, but which retains about 50% of native insulin receptor binding activity. The refolding efficiency of M2PI is higher than proinsulin by 20-40% at alkaline pH, and native insulin is generated by the enzymatic conversion of M2PI. The solution structure of M2PI was determined by NMR spectroscopy. The global structure of M2PI is similar to that of native insulin, but the flexible linker between the B- and A-chains perturbed the N-terminal A-chain and C-terminal B-chain. The helix in the N-terminal A-chain is partly perturbed and the ${\beta}$-turn in the B-chain is disrupted in M2PI. However, the linker between the two chains was completely disordered indicating that the designed turn was not formed under the experimental conditions (20% acetic acid). Considering the fact that an insulin analogue, directly cross-linked between the C-terminus of the B-chain and the N-terminus of the A-chain, has negligible binding activity, a flexible linker between the two chains is sufficient to keep binding activity of M2PI, but the perturbed secondary structures are detrimental to receptor binding.

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A study about logistics costs reduction and improving work safety by way of stocking cart improvement and information sharing plan adopting the SCM theory (SCM 개념의 통합 정보공유 계획과 적재대차 개선을 통한 물류비 절감방안 및 작업안전성 개선에 대한 연구)

  • YANG DOOJIN;LEE CHANGHO;Lee Gong-Seop
    • Proceedings of the Safety Management and Science Conference
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    • 2005.05a
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    • pp.225-230
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    • 2005
  • A study is for the approach that we could reduce the logistics costs through uprising the efficiency, complying to the demand in time, stock management based on the general production plan in the point of SCM. We will take following steps to get the goal. First, we will overview the physical distribution expenses annually. Second, will find the main cause of optimal load loss by improper container and lack of delivery flexibility to the demand. Third, the goal will be inferred through the fast information share based on organic relationship, the establishment of general production plan, the improvement of stock management plan. By way of this process, it can be accomplished expense reduction as well as flexible establishment of the reduction of worker's load.

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A study about logistics costs reduction and improving work safety by way of stocking cart improvement and information sharing plan adopting the SCM theory (SCM 개념의 통합 정보공유 계획과 적재대차 개선을 통한 물류비 절감방안 및 작업안전성 개선에 대한 연구)

  • Yang Doo Jin;Lee Chang Ho
    • Journal of the Korea Safety Management & Science
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    • v.7 no.2
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    • pp.41-56
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    • 2005
  • A study is for the approach that we could reduce the logistics costs through uprising the efficiency, complying to the demand in time, stock management based on the general production plan in the point of SCM. We will take following steps to get the goal. First, we will overview the physical distribution expenses annually. Second, will find the main cause of optimal load loss by improper container and lack of delivery flexibility to the demand. Third, the goal will be inferred through the fast information share based on organic relationship, the establishment of general production plan, the improvement of stock management plan. By way of this process, it can be accomplished expense reduction as well as flexible establishment of the reduction of worker's load.

An Empirical Study on the Determinants of Supply Chain Management Systems Success from Vendor's Perspective (참여자관점에서 공급사슬관리 시스템의 성공에 영향을 미치는 요인에 관한 실증연구)

  • Kang, Sung-Bae;Moon, Tae-Soo;Chung, Yoon
    • Asia pacific journal of information systems
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    • v.20 no.3
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    • pp.139-166
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    • 2010
  • The supply chain management (SCM) systems have emerged as strong managerial tools for manufacturing firms in enhancing competitive strength. Despite of large investments in the SCM systems, many companies are not fully realizing the promised benefits from the systems. A review of literature on adoption, implementation and success factor of IOS (inter-organization systems), EDI (electronic data interchange) systems, shows that this issue has been examined from multiple theoretic perspectives. And many researchers have attempted to identify the factors which influence the success of system implementation. However, the existing studies have two drawbacks in revealing the determinants of systems implementation success. First, previous researches raise questions as to the appropriateness of research subjects selected. Most SCM systems are operating in the form of private industrial networks, where the participants of the systems consist of two distinct groups: focus companies and vendors. The focus companies are the primary actors in developing and operating the systems, while vendors are passive participants which are connected to the system in order to supply raw materials and parts to the focus companies. Under the circumstance, there are three ways in selecting the research subjects; focus companies only, vendors only, or two parties grouped together. It is hard to find researches that use the focus companies exclusively as the subjects probably due to the insufficient sample size for statistic analysis. Most researches have been conducted using the data collected from both groups. We argue that the SCM success factors cannot be correctly indentified in this case. The focus companies and the vendors are in different positions in many areas regarding the system implementation: firm size, managerial resources, bargaining power, organizational maturity, and etc. There are no obvious reasons to believe that the success factors of the two groups are identical. Grouping the two groups also raises questions on measuring the system success. The benefits from utilizing the systems may not be commonly distributed to the two groups. One group's benefits might be realized at the expenses of the other group considering the situation where vendors participating in SCM systems are under continuous pressures from the focus companies with respect to prices, quality, and delivery time. Therefore, by combining the system outcomes of both groups we cannot measure the system benefits obtained by each group correctly. Second, the measures of system success adopted in the previous researches have shortcoming in measuring the SCM success. User satisfaction, system utilization, and user attitudes toward the systems are most commonly used success measures in the existing studies. These measures have been developed as proxy variables in the studies of decision support systems (DSS) where the contribution of the systems to the organization performance is very difficult to measure. Unlike the DSS, the SCM systems have more specific goals, such as cost saving, inventory reduction, quality improvement, rapid time, and higher customer service. We maintain that more specific measures can be developed instead of proxy variables in order to measure the system benefits correctly. The purpose of this study is to find the determinants of SCM systems success in the perspective of vendor companies. In developing the research model, we have focused on selecting the success factors appropriate for the vendors through reviewing past researches and on developing more accurate success measures. The variables can be classified into following: technological, organizational, and environmental factors on the basis of TOE (Technology-Organization-Environment) framework. The model consists of three independent variables (competition intensity, top management support, and information system maturity), one mediating variable (collaboration), one moderating variable (government support), and a dependent variable (system success). The systems success measures have been developed to reflect the operational benefits of the SCM systems; improvement in planning and analysis capabilities, faster throughput, cost reduction, task integration, and improved product and customer service. The model has been validated using the survey data collected from 122 vendors participating in the SCM systems in Korea. To test for mediation, one should estimate the hierarchical regression analysis on the collaboration. And moderating effect analysis should estimate the moderated multiple regression, examines the effect of the government support. The result shows that information system maturity and top management support are the most important determinants of SCM system success. Supply chain technologies that standardize data formats and enhance information sharing may be adopted by supply chain leader organization because of the influence of focal company in the private industrial networks in order to streamline transactions and improve inter-organization communication. Specially, the need to develop and sustain an information system maturity will provide the focus and purpose to successfully overcome information system obstacles and resistance to innovation diffusion within the supply chain network organization. The support of top management will help focus efforts toward the realization of inter-organizational benefits and lend credibility to functional managers responsible for its implementation. The active involvement, vision, and direction of high level executives provide the impetus needed to sustain the implementation of SCM. The quality of collaboration relationships also is positively related to outcome variable. Collaboration variable is found to have a mediation effect between on influencing factors and implementation success. Higher levels of inter-organizational collaboration behaviors such as shared planning and flexibility in coordinating activities were found to be strongly linked to the vendors trust in the supply chain network. Government support moderates the effect of the IS maturity, competitive intensity, top management support on collaboration and implementation success of SCM. In general, the vendor companies face substantially greater risks in SCM implementation than the larger companies do because of severe constraints on financial and human resources and limited education on SCM systems. Besides resources, Vendors generally lack computer experience and do not have sufficient internal SCM expertise. For these reasons, government supports may establish requirements for firms doing business with the government or provide incentives to adopt, implementation SCM or practices. Government support provides significant improvements in implementation success of SCM when IS maturity, competitive intensity, top management support and collaboration are low. The environmental characteristic of competition intensity has no direct effect on vendor perspective of SCM system success. But, vendors facing above average competition intensity will have a greater need for changing technology. This suggests that companies trying to implement SCM systems should set up compatible supply chain networks and a high-quality collaboration relationship for implementation and performance.