• Proceedings of the KIEE Conference
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• 1995.07b
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• pp.962-964
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• 1995

In this paper, an integrated chaos analysis system for EEG (ICASE) is designed for the analysis of brain functions based on the chaos theory. Nonlinear dynamic characteristics of EEG such as 3-D attractor, Poincare section, correlation dimension, Lyapunov exponents and power spectrum are extracted by this system. The results show that chaotic attractors which indicate the presence of deterministic, dynamics of complex nature could be identified from a routine EEG recording for normal and pathological activity. This proves that the chaotic analysis of EEG may be an appropriate tool in the classification of brain activity and thus a possible diagnostic tool.

• Korean Journal of Child Studies
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• v.21 no.2
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• pp.45-56
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• 2000

This study investigated the effects of writing activity integrated with verbal sharing on the diversity of vocabulary and complexity of expression in 33 five-year-old children attending a private kindergarten in Seoul. Subjects were divided into a control group of 16 children and an experimental group of 17 children. The experimental group participated in a 7 week program of writing activities integrated with verbal sharing time. The instrument used for the pre-and post-tests was the writing ability test(Nam Mi Jung, 1996) and the complexity of sentences test(Young Hee No, 1994). Data were analyzed by ANCOVA. The results revealed significant differences between the experimental and control groups in children's diversity of vocabulary and complexity of expression.

• International conference on construction engineering and project management
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• 2011.02a
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• pp.395-398
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• 2011

This paper introduces stochastic cash-flow modeling integrated with simulation based scheduling. The system makes use of CPM schedule data exported from commercial scheduling software, computes the best fit probability distribution functions (PDFs) of historical activity durations, assigns the PDFs identified to respective activities, simulates the schedule network, computes the deterministic and stochastic project cash-flows, plots the corresponding cash flow diagrams, and estimates the best fit PDFs of overdraft and net profit of a project. It analyzes the effect of different distributions of activity durations on the distribution of overdrafts and net profits, and improves reliability compared to deterministic cash flow analysis.

• International Journal of Computer Science & Network Security
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• v.21 no.11
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• pp.43-48
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• 2021

The article proposes a method of modeling a comprehensive indicator for evaluating the effectiveness of regional management of innovation activity. This will make it possible to assess the effectiveness of personnel, financial and credit and foreign economic activity of the regions from the standpoint of an integrated approach. The modeling technique is proposed to be carried out using the tools of taxonomic analysis and the calculation of a complex indicator of the effectiveness of the innovation activity management.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.27 no.3
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• pp.31-36
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• 2004

This paper will describe design process and its results that are minimized unaddressed feature of product development processes. This process provides integrated system design process by context analysis of EIA 632 standard process, interface definition from activity decomposition, integration of related activities, and definition of concurrency & sequential activities flow. This process and method application will contribute to minimize time loss that is emerged from activities iteration by not definitely definition of activities interface.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.44 no.3
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• pp.335-341
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• 2018

This study was carried out to evaluate the possibility of willow plants (the genus Salix) as a cosmetic material. DPPH radical scavenging abilities of 70% ethanol extracts of S. gracilistyla, S. pseudolasiogyne, and S. koriyanagi were significantly increased compared to control. In addition, the treatment of three species of willow plant extracts significantly inhibited the production of nitric oxide (NO) in RAW 264.7 cells, indicating that they had anti-inflammatory activity, and all of them had collagenase inhibitory activity. Among them, the extracts of S. gracilistyla extracts exhibited the highest collagenase inhibitory activity. As a result of analyzing the collagenase inhibitory activity against the solvent fraction of S. gracilistyla extracts, water and butanol fractions showed the highest collagenase inhibitory activity. These results suggested that S. gracilistyla among the willow plants had high collagenase inhibitory activity, and thus it can be utilized for cosmetics as an effective functional cosmetic material in the future.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2001.11a
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• pp.113-113
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• 2001

Stable MCF-7-ERE cells, in which pERE-Luc reporter gene has been stably integrated into the genome of the MCF-7 cells, were used to detect the estrogenic activity of various dietary flavonoids in either pure chemical or mixtures. Estradiol (E2) induced luciferase activity in dose dependent manner and this activity was inhibited by tamoxifen (Tam) concomitant treatment. A large series of flavonoids showed estrogenic activities, corresponding to EC5O values between 0.2 and 9 microM and their mixtures didn't show additive or synergistic effects. And we could find some structure and activity relationship. First, 4-methoxylation and catechol structure decreased estrogenic activities. Second, hydroxylation of 3 position reduced estrogenic effect. Third glycosides of flavonoids showed weak estrogenic activity or no activity. Interestingly, when tested at high concentrations, genistein, kaempferol, biochanin A and chrysin elicited luciferase induction higher than that of the maximum induction by estradiol. And these effects of genistein and kaempferol could not be fully inhibited with tamoxifen

• Korean Journal of Adult Nursing
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• v.19 no.4
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• pp.624-633
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• 2007

Purpose: This study was conducted to develop an integrated undergraduate course including a PBL based on a blended learning strategy, and evaluate learners' responses. Methods: The learning contents of cardiovascular, respiratory, and musculoskeletal medical systems, and nursing diagnoses of 'activity and rest' domain (NANADA's classification II, 2005) were analyzed. Six clinical scenarios with the clients in different life cycles were developed for PBL. Classical lecture and group presentation with on-line self learning were implemented in addition to PBL. The developed course was implemented on 84 junior nursing students in a university for 7 weeks with 5 hours per day, two days per week. Students were asked to complete structured questionnaires including problem solving, critical thinking, and nursing diagnosis differentiation abilities. Results: Learner's evaluation was positive in problem solving skills and in the differentiation ability of nursing diagnoses relevant to an 'activity and rest' functional health pattern. Conclusion: Development and implementation of integrated courses based on a blended learning method need to be continued to enhance students' thinking and self-directed learning abilities. Supporting strategies for individual learners should be added for successful blended learning such as individual on-line feedback and consideration of individual learning outcomes.

• Development and Reproduction
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• v.25 no.4
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• pp.279-291
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• 2021

Hair loss is one of the most common chronic diseases, with a detrimental effect on a patient's psychosocial life. Hair loss results from damage to the hair follicle (HF) and/or hair regeneration cycle. Various damaging factors, such as hereditary, inflammation, and aging, impair hair regeneration by inhibiting the activation of hair follicle stem cells (HFSCs) and dermal papilla cells (DPCs). Formyl peptide receptor 2 (FPR2) regulates the inflammatory response and the activity of various types of stem cells, and has recently been reported to have a protective effect on hair loss. Given that stem cell activity is the driving force for hair regeneration, we hypothesized that FPR2 influences hair regeneration by mediating HFSC activity. To prove this hypothesis, we investigated the role of FPR2 in hair regeneration using Fpr2 knockout (KO) mice. Fpr2 KO mice were found to have excessive hair loss and abnormal HF structures and skin layer construction compared to wild-type (WT) mice. The levels of Sonic hedgehog (Shh) and β-catenin, which promote HF regeneration, were significantly decreased, and the expression of bone morphogenetic protein (Bmp)2/4, an inhibitor of the anagen phase, was significantly increased in Fpr2 KO mice compared to WT mice. The proliferation of HFSCs and DPCs was significantly lower in Fpr2 KO mice than in WT mice. These findings demonstrate that FPR2 impacts signaling molecules that regulate HF regeneration, and is involved in the proliferation of HFSCs and DPCs, exerting a protective effect on hair loss.

• Journal of muscle and joint health
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• v.22 no.3
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• pp.236-244
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• 2015

Purpose: The purpose of this study was to investigate physical activity of elderly women at senior citizen centers and to identify factors influencing physical activity. Methods: The study was conducted from February 22 to April 20, 2013 for 200 elderly women at senior citizen centers in J City. Levels of physical activity, cognitive function, and nutritional status were measured. Results: The total physical activity amount was $2118.94{\pm}2.36$ MET-min. The average cognitive function score was $21.17{\pm}4.63$, and the average nutritional status score was $24.04{\pm}3.37$. There were significant relationships among physical activity, cognitive function, and nutritional status. In addition, there were significant differences of groups of physical activity by levels of cognitive function and nutritional status. Cognitive function, nutritional status, and age were significantly associated with level of physical activity in elderly women. Conclusion: The results showed many older women were doing moderate physical activity. Physical activity was associated with cognitive function and nutritive conditions. Integrated health promotion program needs to be implemented to increase physical activity level, the cognitive function, and nutritive conditions in elderly women.