• Korean Journal of Optics and Photonics
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• v.25 no.4
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• pp.169-192
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• 2014

In this paper, state-of-the-art digital holography and integral imaging have been introduced as practical three-dimensional imaging and display technology. Operational principles and recent research and development activities of these technologies have been discussed, as well as a vision of their future.

• Asian Journal for Public Opinion Research
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• v.5 no.2
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• pp.127-142
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• 2018

The study describes the manner in which participation in SPU Manila's Glee Club is instrumental in the lives of its members. Through a focus group discussion (FGD) involving eight members, the results revealed that the experiences of the students affect the physical, financial, political, and social dimensions of their lives, enabling them to achieve personal goals related to exposure, receive assistance, and develop self-confidence. These benefits result in the satisfaction of most of the members and a desire to continue with the group, provided participation does not get in the way of academic priorities. The study also revealed a desire among students to assert instrumentality in the chorale group as they sought more regular evaluations and frustrations over not being heard by their moderator/s.

• Magazine of the Korean Society of Agricultural Engineers
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• v.34 no.2
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• pp.21-39
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• 1992

Many problems were found out the remarkable unbalance between paddy fields and up-land areas, or between plain and mountainous areas, unreasonable establishing of land consolidaton boundaries without consideration of rural development, lower leverl of construction technology of the roads and canals for agricultral use ad operation and maintenance of them by human power far apart from the ages of high technology, high information and free internationalisation, and too slow progress to overcome the weak agricultural circumstances etc. through the survey in the past executed land consolidation projects. The basic ways for solution of these problems for propulsion of land consolidation project through investigation are summarized as follows : 1. Land consolidation project should be executed to the direction of balanced regional development, laying stress on the upland and mountainous areas in order to carry out the agriculture effectively. 2. the acreage of land consolidation project to be conducted anually should be increased to overcome the serious underdeveloped agricultural development. 3. It should be developed to the way in accordance with the order of land use from the view point of rural integral development including the rural readjustment. 4. The level of the structures of road and canal, the size of standard lot and the grouping of land substitution should be to incraese the productivity of land and labour more than ever and reached to a degree in cope with the age of industrialization, information and free internationalisation. 5. The level of the management of agricultural water use and the maintenace of the various facilities should be developed to be automatization, remote control, central control and information processing instead human work. 6. Land substitution should take a measure of grouping method in accordance with the agricultural plan and farming organization, which can overcome high industrialized society in place of the substition by origin land. 7. Land consolidation project should be planned in order to fulfil a conservative function of ecosystem and resources together with improvement of land and labour productivity.

• BMB Reports
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• v.54 no.10
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• pp.505-515
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• 2021

Human pluripotent stem cells (hPSCs) include human embryonic stem cells (hESCs) derived from blastocysts and human induced pluripotent stem cells (hiPSCs) generated from somatic cell reprogramming. Due to their self-renewal ability and pluripotent differentiation potential, hPSCs serve as an excellent experimental platform for human development, disease modeling, drug screening, and cell therapy. Traditionally, hPSCs were considered to form a homogenous population. However, recent advances in single cell technologies revealed a high degree of variability between individual cells within a hPSC population. Different types of heterogeneity can arise by genetic and epigenetic abnormalities associated with long-term in vitro culture and somatic cell reprogramming. These variations initially appear in a rare population of cells. However, some cancer-related variations can confer growth advantages to the affected cells and alter cellular phenotypes, which raises significant concerns in hPSC applications. In contrast, other types of heterogeneity are related to intrinsic features of hPSCs such as asynchronous cell cycle and spatial asymmetry in cell adhesion. A growing body of evidence suggests that hPSCs exploit the intrinsic heterogeneity to produce multiple lineages during differentiation. This idea offers a new concept of pluripotency with single cell heterogeneity as an integral element. Collectively, single cell heterogeneity is Janus-faced in hPSC function and application. Harmful heterogeneity has to be minimized by improving culture conditions and screening methods. However, other heterogeneity that is integral for pluripotency can be utilized to control hPSC proliferation and differentiation.

• Journal of Cancer Prevention
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• v.22 no.4
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• pp.203-210
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• 2017

After transcription, RNAs are always associated with RNA binding proteins (RBPs) to perform biological activities. RBPs can interact with target RNAs in sequence- and structure-dependent manner through their unique RNA binding domains. In development and progression of carcinogenesis, RBPs are aberrantly dysregulated in many human cancers with various mechanisms, such as genetic alteration, epigenetic change, noncoding RNA-mediated regulation, and post-translational modifications. Upon deregulation in cancers, RBPs influence every step in the development and progression of cancer, including sustained cell proliferation, evasion of apoptosis, avoiding immune surveillance, inducing angiogenesis, and activating metastasis. To develop therapeutic strategies targeting RBPs, RNA interference-based oligonucleotides or small molecule inhibitors have been screened based on reduced RBP-RNA interaction and changed level of target RNAs. Identification of binding RNAs with high-throughput techniques and integral analysis of multiple datasets will help us develop new therapeutic drugs or prognostic biomarkers for human cancers.

• Journal of Korean Philosophical Society
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• v.131
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• pp.353-381
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• 2014

"The four types of temperament" (hereinafter "Sa-Sang Constitutional Medicine") is applied to not only medicine, but also various fields like management, politics, education, etc. Despite that "Sa-Sang Constitutional Medicine" is "Mind-Body Medicine" which is fundamentally based on "Controling Mind and Body", though, it was rarely used for psychotherapy in practical. Practical treatment on clinical medicine is limited to only medicine-treatment or acupuncture-therapy. However treatment on illness and pathological phenomenon suggested by "Sa-Sang Constitutional Medicine" keeps individual's nature in control, and it governs environmental facts: age, region, and socio-cultural factors: alcohol, debauchery, riches, authority(酒 色 財 權). Especially, "Moral Cultivation" in "Sa-Sang Constitutional Medicine" emphasizes the importance of properly understanding vice(邪心) and laziness(怠行) concealed in natural temperament of human being, and pursuing "Understanding Each Other(博通)" and "Upright Conduct by Oneself(獨行)". Furthermore, because "Sa-Sang Constitutional Medicine" is developing medical theory based on "Understanding Others(知人)" and "Straighten Oneself(正己)" doing try integral approach, it has great implications for the present generation that forms much of social connection. Similarly, Ken Wilber who is one of representatives of "World Philosophy" and "Integral Psychology" is suggesting "Integral Life Practice" (hereinafter ILP) - applies practical and heuristic "Integral Approach" to individual experiences. ILP is the only practical discipline for development of viable whole-area. ILP says that there are four core modules: body, mind, shadow, spirit(靈), and five auxiliary modules: morals(倫理), gender(性), work(일), emotion(情緖), relationships(關係性). These nine modules could apply mind-body treatment of "Sa-Sang Constitutional Medicine", and thereby more developed mind-body treatment would be found.

• Health Policy and Management
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• v.14 no.3
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• pp.97-121
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• 2004

Recently, human embryonic stem cell research raises exciting public expectation on medical possibilities as well as ethical debate. Embryo management has become an integral part of the management of infertility treatment, researches on embryo and human embryonic stem cells and so on. Britain has permitted the research on stem cells derived from human embryo which made the first nation to allow the cloning of human embryo for the stem cell research. However, new technologies such as the assisted reproductive technologies and human embryonic stem cell research continue to pose an increasing source of ethical dilemmas for physician, scientists, legislators, religious authorities and the general publics to deal with. None the less, the United Kingdom has adopted the most liberal policies regarding human embryo and human embryonic stem cell research. The implication of the British embryo management system are as follows: 1) the development of reproductive technologies and new stem cell research technologies continue to pose legal and ethical debates, since those involve several parties; 2) the UK has taken the legal and institutional approaches to cope with those serious issues; 3) the UK adopted most liberal policies regarding embryonic and human embryonic stem cell researches; 4) the British HFE Act is consistent with the existing Acts related to human embryo management and researches; 5) through amending the HFE Act to accomodate the changes of technologies, the UK try to minimize the legal and ethical burden on undertaking research regarding embryo. The debates about the researches on human embryo and human embryonic stem cells is likely to continue in the Korean society. Because of the controversy and competing ethical values, as well as the evolving technologies, so far no consensus exists in our society. It suggest that it is premature to bring closure by ruling out any particular approaches. Thus our society needs to make an efforts to find a basis which could resolve the societal controversies through enriching the societal conversation about the profound ethical issues regarding embryo management.

• Journal of East-West Nursing Research
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• v.14 no.2
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• pp.60-66
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• 2008

Background: Communication training in nursing college students is an integral part of the development of their competency in dealing with patients. However, the traditional lecture style of training delivery may not be desirably effective. Purpose: This study investigated the effects of a communication training program utilizing a small group dynamic on the communication competency and human relationships in nursing college students. Methods: One hundred twenty six freshmen in a university in Seoul participated in this study. The instruments of communication competency (Primary Communication Inventory) and human relationships (Relationship Change Scale) were used at the beginning and conclusion of the training period. Eighty-three students from two nursing classes were assigned to the experimental groups and 43 students from other classes were assigned to the control groups. Each of the 11 small groups was composed of 7 or 8 students. The weekly program that ran during the 2007 fall semester from October 1st to December 11th consisted of effective communication strategies including therapeutic communication skills, Johari's window, empathy, active listening, and transactional analysis. Results: The experimental group of students reported significantly greater improvement in communication competencies, specific nonverbal competencies, and human relationships compared with the control group. Specifically, the experimental students demonstrated greater improvement in nonverbal communication competencies and satisfaction, communication, and awareness of human relationships. Conclusions: Small group based communication training can be an effective alternative method of communication education for college nursing students.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.41 no.8
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• pp.691-701
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• 2017

The barbell squat is a fundamental physical exercise for strengthening the lower body and core muscles. It is an integral part of training and conditioning programs in sports, rehabilitation, and fitness. In this paper, we proposed a virtual test framework for squat exercises using a Smith machine to simulate joint torques and muscle forces, based on an integrated product-human model and motion synthesis algorithms. We built a muscular skeletal human model with boundary conditions modeling the interactions between the human body and a machine or the ground. To validate the model, EMG, external forces, and squat motions were captured through physical experiments by varying the foot position. A regression-based motion synthesis algorithm was developed based on the captured squat motions to generate a new motion for a given foot position. The proposed approach is expected to reduce the need for physical experiments in the development of training programs.

• Journal of Family Resource Management and Policy Review
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• v.8 no.3
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• pp.113-125
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• 2004

This study aims to provide philosophical frameworks and approaches, and practical guidelines to interview research. While there are some studies which focus on the practical guidelines, there is a lack of studies which address the philosophical and conceptual issues integral to qualitative interview research. By discussing three different but related philosophical aspects of qualitative interviewing--phenomenology, hermeneutics, and dialectics--consistency among research purpose, research method, research methodology is pursued. Based on this discussion, four stages of interviewing--designing, conducting, analyzing, and writing of qualitative interview research--are presented.