• Journal of Veterinary Clinics
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• v.41 no.2
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• pp.127-132
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• 2024

A 6-month-old intact female Bichon Frise dog weighing 0.9 kg presented with vomiting, anorexia, and lethargy persisting for 3 days. No remarkable abnormalities were detected on the history or physical examination. Laboratory findings were mostly normal, except for elevated levels of alkaline phosphatase (ALP) and blood urea nitrogen (BUN). Abdominal radiography revealed a fluid-dilated stomach and gas-dilated intestinal loops in the regional areas. Abdominal ultrasonography was performed to investigate the cause of gastrointestinal dilation, which revealed a rectangular, homogeneous, echogenic foreign material with no shadowing in the small intestine, causing mechanical obstruction. Upon further inquiry involving detailed re-take of history with the owner, a history of ingesting dog gum 4 days prior was identified. On surgical enterotomy, the hard pet food was identified and removed from the distal duodenum. Postoperatively, the patient's clinical signs showed complete improvement, with a return to normal appetite. The present case demonstrates that less-digestible, hard pet food, despite showing no shadowing on ultrasonography, can act as a foreign material, causing mechanical intestinal obstruction in a small-breed puppy. Furthermore, surgical removal of these materials is necessary in cases of intestinal obstruction.

• Journal of the Korean Geotechnical Society
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• v.16 no.3
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• pp.5-13
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• 2000

In this study, the Disturbed State Concept (DSC) constitutive model is calibrated and modified for steel-sand interface by using the HiS S model for relative intact (Rl) state and the critical state model for the fuBy adjusted (FA) part in the material. The general formulation for implementation is developed. Then, the DSC model with modification for interface is implemented in finite element program based on the generalized Biot's theory. The interface test under one-way monotonic and two-way cyclic loading were numerically simulated using the finite element program modified in this study. The DSC predictions show improved agreement with the observed results from laboratory test. Overall, the computer procedure with the DSC allows relatively improved simulation ofthe soil-structure interaction problems.oblems.

• Journal of Korean Tunnelling and Underground Space Association
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• v.8 no.2
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• pp.87-100
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• 2006

A kinematically constrained microplane constitutive model is developed for intact granite. The model is verified by fitting the experimented data of Westerly granite and Bonnet granite. Using the model with the standard finite element method, the behavior of the intact granite subjected blasting impact is studied. What is studied includes the attenuation of the blasting waves, the size of the fractured zone and the effect of the charge condition to avoid overbreak of the rock mass. The model developed captures the energy loss due to the inelastic behavior and the microcracking of granite during blasting very well. The attenuation of the blasting waves calculated based on the model is much more than that based on the linear-elastic constitutive law. The size of damaged (or fractured) zone is calculated directly from the principal strain as blasting impact is spreading, not like in the case with the linear elasticity model.

• Plant Biotechnology Reports
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• v.3 no.4
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• pp.317-324
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• 2009

The insecticidal toxin gene of Bacillus thuringiensis (Bt) is one of the most commonly used in the development of genetically modified (GM) crops. In this research, we analyzed Bt rice showing lepidopteran pest-resistance. The Bt gene is a synthetic Cry1Ac composed of optimal codons for plants, and the Bt protein is targeted to the chloroplast by a transit peptide. Three Cry1Ac rice events (C103-3, C127-1, and C7-1) were analyzed for molecular characterization. C103-3 contains two copies of T-DNA where the left border (LB) region is truncated. Both C7-1 and C127-1 have a single copy of T-DNA, but a part of the vector backbone DNA is inserted into the genome of C127-1; thus, only C7-1 had intact T-DNA. Progenies of C7-1 crossed with the original cultivar, Nakdong, and double-haploid lines from anther culture of lines crossed with the elite cultivar, Dongjin, were analyzed for T-DNA flanking genomic DNA and genotyping. Results showed that an intact T-DNA region without the vector backbone was inserted into the genome and was stably inherited through generations. The C7-1 homozygous event could be used as breeding material to develop GM rice with pest resistance.

• Journal of Korean Society of Steel Construction
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• v.18 no.2
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• pp.137-146
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• 2006

In this paper, a numerical study on the evaluation of the redundancy according to the dimension and spacing of cross beams in the composite twin steel plate girder bridges that are generally recognized as a non-redundant load path structures, has been performed. Specifically, a two-lane three-span continuous (40+50+40m) bridge with I-section cross beams which serve as cross bracing, and without a lateral bracing were considered. The material and geometric nonlinear analyses were conducted to evaluate the ultimate loading capacity of the intact and damaged bridge in which one of the two girders is seriously fractured. Through the numerical analyses, it was recognized that there is little difference in redundancy according to the variation of the dimension and spacing of the cross beams for both intact and damaged bridges.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.4A
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• pp.611-620
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• 2006

The composite two plate-girder bridges are generally defined as a non-redundant load path structure because the bridge can collapse if one of the two girders is seriously damaged by a fatigue crack. In this paper, a numerical study on the evaluation of the after-fracture redundancy of the composite two-girder bridges was accomplished. The evaluation has been performed on the simple and three-span continuous bridges with I-section cross beams which serve as transverse bracing, and with or without the bottom lateral bracing system. The load carrying capacities of the intact and damaged bridges with or without lateral bracing were evaluated from material and geometric nonlinear analysis, respectively and the redundancy was evaluated for each case. It was acknowledged from the analytical results that both simple and continuous intact two-girder bridges have sufficient redundancy even without lateral bracing, but it takes an important role to improve the redundancy of damaged bridges.

• KSBB Journal
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• v.25 no.3
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• pp.257-264
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• 2010

Bone morphogenetic protein-7 (BMP-7) is one of important growth factors for skeletal development and bone growth. In this work, BMP-7 was efficiently expressed in recombinant Bacillus subtilis. The mature BMP-7 protein indicated molecular weight of 15.4 kDa by Western blot assay and was secreted into culture medium with 0.35 ng/mL. The extracellular and intracellular rhBMP-7 proteins were purified by using a FPLC system with an ion exchange column and a gel filtration column. The extracellular and intracellular rhBMP-7 proteins had finally a 57.1% purity and a 36.2% purity, respectively. The purified rhBMP-7 proteins showed an intact biological activity which stimulated alkaline phophatase (ALP) activity in MC3T3-E1 cells.

• Proceedings of the Korean Geotechical Society Conference
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• 2005.03a
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• pp.1484-1489
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• 2005

An inhomogeneous and anisotropic rock has different properties at different location. Thus, this refers to any of the properties which we may be measuring. There are two concepts of rock mass, namely, CHILE(Continuous, Homogeneous, Isotropic, Linear Elastic) material and DIANE(Discontinuous, Inhomogeneous, Anisotropic, Non-linear Elastic) rock. The former is essentially the properties of intact rock, the latter is essentially the properties governed by the structure of rock. In geotechnical aspect, the most important parameter is strength of rock or rock mass. In particular, characteristics of strength of rock mass depend upon the orientation of discontinuities And this orientation of discontinuities has different properties at different direction of excavation. Therefore, it needs for characterization of different properties of discontinuity orientation against different direction of excavation.

• Journal of the Korean Society for Nondestructive Testing
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• v.25 no.3
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• pp.178-188
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• 2005

This paper introduces a structural damage identification method to identify 4he multiple directional damages generated within a cylindrical shell by using the measured frequency response function (FRF). The equations of motion for a damaged cylindrical shell are derived. by using a theory of continuum damage mechanics in which a small material volume containing a directional damage is represented by the effective orthotropic elastic stiffness. In contrast with most existing vibration-based structural damage identification methods which require the modal Parameters measured in both intact and damaged states, the present method requires only the FRF-data measured at damaged state. Numerically simulated damage identification tests are conducted to verify the feasibility of the Proposed structural damage identification method.

• Proceedings of the Korea Concrete Institute Conference
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• 2005.05a
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• pp.391-394
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• 2005

A theoretical model was developed to predict the shear strength of slender reinforced concrete beams. The shear force applied to a cross-section of the beam was assumed to be resisted primarily by the compressive zone of intact concrete rather than by the tensile zone. The shear capacity of the cross section was defined based on the material failure criteria of concrete: failure controlled by compression and failure controlled by tension. In the evaluation of the shear capacity, interaction with the normal stresses developed by the flexural moment in the cross section was considered. In the proposed strength model, the shear strength of the beam and the location of the critical section were determined at the intersection between the shear capacity and shear demand curves. The proposed strength model was verified by the comparisons to prior experimental results.