• 한국의류산업학회지
• /
• 제25권4호
• /
• pp.429-438
• /
• 2023

In the 21st century fashion industry, the rise of digital environments has transformed it into a dynamic medium, expanding the horizons of media utilization. Consequently, digital fashion film has emerged as a pivotal tool for fashion communication. Functioning as a visual expression medium, fashion film animates fashion concepts into immersive moving images. Proficiency in digital fashion communication has become imperative, considering the attributes of fashion media. Notably, the role of creative directors in ensuring coherent communication across diverse fashion media platforms has gained prominence, underscoring the need for systematic fashion education to nurture specialized talent. This study, therefore, devised a comprehensive curriculum amalgamating fashion communication and practical digital media skills, implemented within fashion major courses. Through this approach, students gained experimental media proficiency and explored innovative approaches to crafting fashion films that eloquently convey fashion narratives. The participants were exposed to the entire spectrum of fashion media production, encompassing digital storytelling, fashion film conceptualization, filming techniques, meticulous editing, and adept utilization of special effects technology. The study's pedagogical strategy, characterized by a focused learning trajectory, garnered significant acclaim. In essence, this study holds significance by formulating a curriculum that nurtures the imaginative and pragmatic aptitudes of fashion majors, immersing them in the dynamic realm of rapidly evolving digital fashion films and their integration with fashion content.

• International Journal of Advanced Culture Technology
• /
• 제11권2호
• /
• pp.409-414
• /
• 2023

In recent years, the emergence of a number of AI image generation software represented by [Midjourney] has brought great impetus to the development of the field of AI-assisted art creation. Compared with the traditional hand-painted digital painting with the aid of electronic equipment, broke the traditional sense of animation character creation logic.This paper analyzes the application of AI technology in the field of animation character design through the practice of two-dimensional animation character . This is having a significant impact on the productivity and innovation of animation design and character modeling. The key results of the analysis indicate that AI technology, particularly through the utilization of "Midjourney,"enables the automation of certain design tasks, provides innovative approaches, and generates visually appealing and realistic characters. In conclusion, the integration of AI technology, specifically the application of "Midjourney," brings a new dimension to animation character design. The utilization of AI image generation software facilitates streamlined workflows, sparks creativity, and improves the overall quality of animated characters. As the animation industry continues to evolve, AI-assisted tools like "Midjourney" hold great potential for further advancement and innovation.

• 한양메디칼리뷰
• /
• 제33권1호
• /
• pp.59-64
• /
• 2013

Cancer remains the leading cause of death worldwide despite intense efforts in developing innovative treatments. Current approaches in cancer therapy are mainly directed to a selective targeting of cancer cells to avoid potential side effects associated with conventional therapy. In this respect, Natural killer (NK) cells have gained growing attention and are now being considered as promising therapeutic tools for cancer therapy owing to their intrinsic ability to rapidly recognize and kill cancer cells, while sparing normal healthy cells. NK cells play a key role in the first line of defense against transformed and virus-infected cells. NK cells sense their target through a whole array of receptors, both activating and inhibitory. Functional outcome of NK cell against target cells is determined by the balance of signals transmitted from diverse activating and inhibiting receptors. Despite significant progress made in the role of NK cells attack as a pivotal sentinel in tumor surveillance, the molecular has been that regulate NK cell responses remain unclear, which restricts the use of NK cells as a therapeutic measure. Accordingly, current efforts for NK cell-based cancer therapy have largely relied on the strategies that are based on the manipulation of inhibitory receptor function. However, if we better understand the mechanisms governing NK cell activation, including those mediated by diverse activating receptors, this knowledge can be applied to the development of optimal design for cancer immunotherapy by targeting NK cells.

• Steel and Composite Structures
• /
• 제45권3호
• /
• pp.455-466
• /
• 2022

Despite the considerable lateral stiffness and strength of the Concentrically Braced Frame (CBF), it suffers from low ductility and low seismic dissipating energy capacity. The buckling of the diagonal members of the CBF systems under cyclic loading ended up to the shortcoming against seismic loading. Comprehensive researches have been performing to achieve helpful approaches to prevent the buckling of the diagonal member. Among the recommended ideas, metallic damper revealed a better success than other ideas to enhance the behavior of CBFs. While metallic dampers improve the behavior of the CBF system, they increase constructional costs. Therefore, in this paper, a new steel damper with flexural mechanism is proposed, which is investigated experimentally and numerically. Also, a parametrical revision was carried out to evaluate the effect of thickness, slenderness ratio, angle of the main plate, and height of the main plates on the proposed damper. For the parametrical study, 45 finite element models were analyzed and considered. Experimental results, as well as the numerical results, indicated that the proposed damper enjoys a stable hysteresis loop without any degradation up to a high rotation equal to around 31% that is significantly considerable. Moreover, it showed a suitable performance in case of ductility and energy dissipating. Besides, the necessary formulas to design the damper, the required relations were proposed to design the elements outside the damper to ensure the damper acts as a ductile fuse.

• 전기전자학회논문지
• /
• 제27권4호
• /
• pp.430-438
• /
• 2023

The Modular Multilevel Converter (MMC) has emerged as a key component in HVDC systems due to its ability to efficiently transmit large amounts of power over long distances. In such systems, accurate estimation of the MMC capacitor voltage is of utmost importance for ensuring optimal system performance, stability, and reliability. Traditional methods for voltage estimation may face limitations in accuracy and robustness, prompting the need for innovative approaches. In this paper, we propose a novel distributed neural network observer specifically designed for MMC capacitor voltage estimation. Our observer harnesses the power of a multi-layer neural network architecture, which enables the observer to learn and adapt to the complex dynamics of the MMC system. By utilizing a distributed approach, we deploy multiple observers, each with its own set of neural network layers, to collectively estimate the capacitor voltage. This distributed configuration enhances the accuracy and robustness of the voltage estimation process. A crucial aspect of our observer's performance lies in the meticulous initialization of random weights within the neural network. This initialization process ensures that the observer starts with a solid foundation for efficient learning and accurate voltage estimation. The observer iteratively updates its weights based on the observed voltage and current values, continuously improving its estimation accuracy over time. The validity of proposed algorithm is verified by the result of estimated voltage at each observer in capacitor of MMC.

• 국제학술발표논문집
• /
• The 4th International Conference on Construction Engineering and Project Management Organized by the University of New South Wales
• /
• pp.117-123
• /
• 2011

The Australian construction industry is characterized as being a competitive and risky business environment due to lack of cooperation, insufficient trust, ineffective communication and adversarial relationships which are likely lead to poor project performance. Relational contracting (RC) is advocated by literature as an innovative approach to improve the procurement process in the construction industry. Various studies have collectively added to the current knowledge of known RC norms, but there seem to be little effort on investigating the determinants of RC and its impact on project outcomes. In such circumstances, there is lack of evidence and explanation on the manner on how these issues lead to different performance. Simultaneously, the New Engineering Contract (NEC) that embraced the concept of RC is seen as a modern way of contracting and also considered as one of the best approaches to the perennial problem of improving adversarial relationships within the industry. The reality of practice of RC in Australia is investigated through the lens of the NEC. A synthesis of literature views on the concept, processes and tools of RC is first conducted to develop the framework of RC. A case study approach is proposed for an in-depth analysis to explore the critical issues addressed by RC in relation to project performance. Understanding the realities of RC will assist stakeholders in the construction industry with their investment in RC.

• The Korean Journal of Physiology and Pharmacology
• /
• 제28권3호
• /
• pp.197-207
• /
• 2024

The potential of tivozanib as a treatment for oral squamous cell carcinoma (OSCC) was explored in this study. We investigated the effects of tivozanib on OSCC using the Ca9-22 and CAL27 cell lines. OSCC is a highly prevalent cancer type with a significant risk of lymphatic metastasis and recurrence, which necessitates the development of innovative treatment approaches. Tivozanib, a vascular endothelial growth factor receptor inhibitor, has shown efficacy in inhibiting neovascularization in various cancer types but has not been thoroughly studied in OSCC. Our comprehensive assessment revealed that tivozanib effectively inhibited OSCC cells. This was accompanied by the suppression of Bcl-2, a reduction in matrix metalloproteinase levels, and the induction of intrinsic pathway-mediated apoptosis. Furthermore, tivozanib contributed to epithelial-to-mesenchymal transition (EMT) inhibition by increasing E-cadherin levels while decreasing N-cadherin levels. These findings highlight the substantial anticancer potential of tivozanib in OSCC and thus its promise as a therapeutic option. Beyond reducing cell viability and inducing apoptosis, the capacity of tivozanib to inhibit EMT and modulate key proteins presents the possibility of a paradigm shift in OSCC treatment.

• 한국포장학회지
• /
• 제30권1호
• /
• pp.31-42
• /
• 2024

This review paper provides a detailed analysis of PET (polyethylene terephthalate) bottle recycling in Japan. Japan is a global leader in PET bottle recycling due to its advanced regulatory framework and proactive industry initiatives. Japan's success attributes to the widespread adoption of bottle-to-bottle recycling, driven by the beverage industry's commitment to sustainability. By utilizing post-consumer PET bottle recovery and food-grade mechanical recycling technologies, Japan has achieved significant milestones in PET bottle recycling. This paper examines regulatory frameworks, collection systems, reprocessing facilities, and food safety assessments to highlight Japan's innovative approaches to PET bottle recycling and their impact on global sustainability efforts. Drawing parallels with Korea's early stages of PET recycling, it suggests involving major beverage companies and re-evaluating regulations to promote bottle-to-bottle recycling. The focus is on the implications for Korea to promote circular economy principles in plastic recycling.

• 한국축산식품학회지
• /
• 제44권2호
• /
• pp.255-268
• /
• 2024

Probiotic products have long been recognized for their health benefits. Additionally, milk has held a longstanding reputation as a dairy product that offers high-quality proteins and essential micronutrients. As awareness of the impact of food on health grows, interest in functional products such as probiotic dairy products is on the rise. Fermentation, a time-honored technique used to enhance nutritional value and food preservation, has been used for centuries to increase nutritional value and is one of the oldest food processing methods. Historically, fermented dairy products have been used as convenient vehicle for the consumption of probiotics. However, addressing the potential drawbacks of fermentation has recently led to increase in research on probiotic dairy drinks prepared without fermentation. These non-fermented dairy drinks have the advantage of maintaining the original flavors of milk drinks, containing potential health functional probiotics, and being an alternative dairy product that is helpful for probiotics intake. Currently, research on plant-based dairy products is rapidly increasing in the market. These developments might suggest the potential for novel forms of non-fermented dairy beverages with substantial prospects in the food market. This review aims to provide an overview of milk-based dairy beverages, both fermented and non-fermented, and discuss the potential of non-fermented dairy products. This exploration paves the way for innovative approaches to deliver probiotics and nutrition to consumers.

• Journal of Yeungnam Medical Science
• /
• 제40권4호
• /
• pp.328-334
• /
• 2023

An aging population and changes in dietary habits have increased the incidence of diabetes, resulting in complications such as diabetic foot ulcers (DFUs). DFUs can lead to serious disabilities, substantial reductions in patient quality of life, and high financial costs for society. By understanding the etiology and pathophysiology of DFUs, their occurrence can be prevented and managed more effectively. The pathophysiology of DFUs involves metabolic dysfunction, diabetic immunopathy, diabetic neuropathy, and angiopathy. The processes by which hyperglycemia causes peripheral nerve damage are related to adenosine triphosphate deficiency, the polyol pathway, oxidative stress, protein kinase C activity, and proinflammatory processes. In the context of hyperglycemia, the suppression of endothelial nitric oxide production leads to microcirculation atherosclerosis, heightened inflammation, and abnormal intimal growth. Diabetic neuropathy involves sensory, motor, and autonomic neuropathies. The interaction between these neuropathies forms a callus that leads to subcutaneous hemorrhage and skin ulcers. Hyperglycemia causes peripheral vascular changes that result in endothelial cell dysfunction and decreased vasodilator secretion, leading to ischemia. The interplay among these four preceding pathophysiological factors fosters the development and progression of infections in individuals with diabetes. Charcot neuroarthropathy is a chronic and progressive degenerative arthropathy characterized by heightened blood flow, increased calcium dissolution, and repeated minor trauma to insensate joints. Directly and comprehensively addressing the pathogenesis of DFUs could pave the way for the development of innovative treatment approaches with the potential to avoid the most serious complications, including major amputations.