• Archives of Plastic Surgery
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• 제42권3호
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• pp.282-287
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• 2015

Background Morphological changes that accompany aging, such as wrinkles and skin laxity, are particularly prominent on facial skin. Recently, facial rejuvenation using the hydrofilling effect of hyaluronic acid (HA) filler has been employed for improvement of skin texture. In this study, we studied rejuvenating effects of stabilized HA (Restylane Vital) through direct intradermal injections. Methods A total of 30 female patients underwent a series of procedures on face, including three sessions at intervals of four weeks. A total of 2 mL of Restylane Vital was injected along the whole face using an automatic injector. Improvement of skin surface roughness, elasticity, brightness, moisture, and fine wrinkles was evaluated. Patient satisfaction was evaluated, and pictures of patients were taken at each visit and 6 months after last treatment session. Scoring for each patient was performed by three doctors according in five subjects. Moisture, oil and elasticity were measured before the procedure and before the last treatment in 10 patients. Results The majority of patients (77%) were satisfied with the therapeutic outcomes. Approximately 66% of patients responded that the effects of this procedure persisted for longer than four months, and the majority of patients (77%) wanted to undergo this procedure again and would recommend this procedure to acquaintances. Regarding doctors' evaluation, scores for improvement of skin surface roughness, elasticity, and brightness were significantly higher than those for improvement of moisture and fine wrinkle. Conclusions Intradermal injection of HA can have a rejuvenating effect on dry and tired facial skin, especially in improvement of skin surface roughness.

• 에너지공학
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• 제16권3호
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• pp.120-127
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• 2007

본 연구의 목적은 디젤연소장의 분위기조건에 따라 다성분 혼합연료의 질량분률이 분무착화 및 연소특성에 미치는 영향을 실험적으로 고찰하는데 있다. 착화 및 연소특성은 화학발광계측법 및 직접촬영법을 이용하여 분석되었다. 실험은 광계측기를 사용하여 RCEM에서 이루어졌으며, 이소옥탄, 노말 도데칸, 노말 헥사데칸으로 혼합한 다성분연료는 커먼레일 인젝터의 전자제어에 의해 RCEM의 연소실 내로 분사된다. 실험조건은 분사압력 42, 72, 112 MPa과 분위기온도 700, 800, 900 K로 하였다. 그 결과로서 착화지연은 고세탄가성분에 의존하고, 분위기온도가 낮을 경우 저비점성분 혼합비율의 증가에 따라 휘도영역이 현저하게 낮아지며, 열발생률이 증가하면서 확산연소기간을 단축시킨다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2006년도 춘계학술대회 논문집
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• pp.585-586
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• 2006

In this paper, we present a design, analysis, fabrication and performance test of the novel DoD metal-jet system for application to the high-density and high-temperature-melting materials. Based on the theoretical analysis, we design the metal-jet print head system and fabricate the metal-jet system, which can eject the droplet of lead-free metal solder in the high-temperature. In the experimental test, we set up the test apparatus for visualization of the droplet ejection and measure the Ejected droplet volume and velocity. As a result, the diameter, volume and the velocity of the ejected droplet are about $65-70{\mu}m$, 145-180 pl and 4m/sec. We also fabricate vertical and inclined 3D micro column structures using the present molten metal inkjet system. The measured geometries of the micro column structures are about height of $2,100{\mu}m$, diameter of $200{\mu}m$ and aspect ratio of 10.5 for vertical micro column and $1,400{\mu}m$ of height and $150{\mu}m$ of diameter for $65^{\circ}$-inclined micro column, respectively.

• 한국수정란이식학회지
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• 제15권1호
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• pp.77-83
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• 2000

The purpose of this study was to develop a breeding technique to increase Hanwoo of superior characteristics. In the present study, reproductive status of Hanwoo such as size of farm, breeding system and gestationi length was investigated. In addition, effect of low dose administration of prostaglandin F2$\alpha$(PGF2$\alpha$) on luteolysis was examined. The size of farm was classified by the total number of cows and the number of breeding stocks, respectively. The distribution of herd size of < 5, 6~10, 11~30, 31~50 and > heads was 31%, 15%, 39%, 4% and 11%, respectively. Furthermore, the distribution of breeding stock size of <5, 6~10, 11~30, 31~50 and > 50 heads was 36%, 28%, 31%, 3% and 3%, respectively. Average parity was 2.1 in breeding stock. In breeding pattern, artificial in semination(A.I), estrus synchronization-A.I and natural mating was 92.7%, 2.4% and 4.9% respectively. Gestational length of Hanwoo was ranged 253~316 days (average length : 285 days) after estrus( estrus=0). To induce luteolysis, PGF2$\alpha$ was injected into ovarian parenchyma by a modified ovarian injector. The effect of administration of 6mg PGF2$\alpha$ on luteolysis and estrus induction was betweer (P<0.01) when PGF2$\alpha$ was administered into ovarian parechyma than when administered intramuscluarly (71 vs. 91%). When PGF2$\alpha$ was injected into ovarian parenchyma, a decreased concentration to 3 mg did not significantly decreaed its luteolytic effect(92%). When AI was performed following PGF2$\alpha$ treatment, the intraovarian injection group yielded a higher pregnancy rate(69 vs. 88%) than the IM injection groups, regardless of the dosage. In conclusion these results suggest that increasing herd size and regular reproductive management are needed to improve reproductive efficiency in Hanwoo industry. Furthermore, intraovarian administration of PGF2$\alpha$ is effective way to induce luteolysis compared with intramuscular injection.

• 한국재료학회지
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• 제14권6호
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• pp.402-406
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• 2004

$WSi_2$, $TiSi_2$, $CoSi_2$, and $TaSi_2$ are general silicides used today in semiconductor devices. $WSi_2$ thin films have been proposed, studied and used recently in CMOS technology extensively to reduce sheet resistance of polysilicon and $n^{+}$ region. However, there are several serious problems encountered because $WSi_2$ is oxidized and forms a native oxide layer at the interface between $WSi_2$ and $Si_3$$N_4$. In this study, we have introduced 20 $slm-N_2$ gas from top to bottom of the furnace in order to control native oxide films between $WSi_2$ and $Si_3$$N_4$ film. In resulting SEM photographs, we have observed that the native oxide films at the surface of $WSi_2$ film are removed using the long injector system.

• 한국자동차공학회논문집
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• 제23권2호
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• pp.221-229
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• 2015

The PFI dual injection engine using one injector per an intake port was developed for solving the DISI engine cost problem. Excellent fuel atomization and targeting of the PFI dual injection engine made enhancement on the fuel efficiency and engine power. In order to develop a PFI dual injection engine, characteristics of the in-cylinder flow and fuel behavior with respect to fuel injection angle and cone angle of the PFI dual injection engine was investigated. Numerical calculation was conducted to analyze 3D unsteady in-cylinder flow and fuel behavior using STAR-CD. The engine operating condition was 2,000rpm at WOT. As a result, the amount of intake air, evaporated fuel and fuel film according to injection angle and cone angle were presented. The results were influenced by interaction between injected fuel and intake port wall.

• Journal of Pharmaceutical Investigation
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• 제22권3호
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• pp.197-204
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• 1992

A gas chromatographic method using nitrogen phosphorous selective detection was developed for simultaneous determination of haloperidol and its metabolite, reduced haloperidol, in human plasma. Combelen was used as internal standard, The method involved extraction and trimethylsilylation followed by the injection of $2-4\;{\mu}l$ of benzene layer, which was used to dissolve the trimethylsilylated derivatives of haloperidol and reduced haloperidol, onto SE-54 column [5% phenyl methyl silica fused capillary column, $16m{\times}0.22\;mm$ $(I.D.){\times}0.33\;{\mu}m$ (coated thickness)]. The temperature of column oven was programmed from $200^{\circ}C\;to\;300^{\circ}C$ at the increase rate of $10^{\circ}C/min and also the temperatures of injector and detector were set at $300^{\circ}C$. Helium was used as carrier gas and its flow rate was maintained at 30 ml/min. The detection was conducted with nitrogen phosphorous selective detector. The retention times for combelen, reduced haloperidol and haloperidol were found to be 9.14, 9.75 and 9.99 min, respectively. The detection limits for haloperidol and reduced haloperidol in human plasma were both 0.2 ng/ml. The coefficients of variation of the intra-assay were generally low (below 9.8%). The mean absolute recoveries of added haloperidol and reduced haloperidol from plasma were 72% and 84%, respectively. No interferences from endogenous substances were found.

• 한국산학기술학회논문지
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• 제15권8호
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• pp.4729-4735
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• 2014

적극적인 환경보호를 위해 그동안 상대적으로 소홀하였던 오프로드 엔진에 대한 배기가스 배출 규제가 강화되고 있다. 본 연구에서는 NOx와 PM 배출물 특성을 고려하여 오프로드 디젤 엔진의 강건 설계를 수행하였다. 이를 위하여 실험계획법에 따라 배출물 NOx와 PM의 측정 실험을 수행하고 다구찌 기법으로 망소 SN 비를 산출하고 분산 분석을 수행하였다. NOx와 PM 배출량에 영향을 미치는 제어 인잘로 인젝터 홀 수, 연료 분사 시기, EGR 율을 선택하였으며 각 제어 인자에 대하여 2 또는 3 수준을 고려하여 직교 배열표를 작성하였고, 이에 근거하여 실험을 수행하였다. 망소 SN 비를 산출하고 델타 통계량을 계산하였다. 저부하 운전 조건에서는 분사 시기가 NOx 배출량에 가장 큰 영향을 미치며, EGR 율이 PM 배출량에 가장 큰 영향을 미치는 결과를 얻었다. 제어 인자들에 대한 신뢰수준은 90% 이상이었다.

• 대한디지털의료영상학회논문지
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• 제16권1호
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• pp.27-33
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• 2014

The purpose of this study evaluated the hemo-dynamic information within 30 seconds clinically in 3D breast MRI. From January to March 2014, A total of 40 people were examined at 1.5 Tesla(Philips, Medical System, Achieva, The Netherlands) MRI equipments using 16 channel SENSE breast coil. The imaging parameters on vibrant are fellow as: $TR/TE/FA^{\circ}$/Matrix size/Slice thickness/Slab($5ms/2ms/10^{\circ}/180{\times}139{\times}2mm/80$). This study used a Gadovist and injected it with injection speed of 4 ml /sec by auto injector with 15 ml saline flushing. Firstly, for the delay time study, it divided three different delay time from immediately, 20 seconds, and 30 seconds. In quantitative analysis, the ROI signal intensities of tumor and surrounding tissues were measured retrospectively. In qualitative analysis, the image quality was scored from 1 to 5 point by one experienced radiological technologists as a visual test. The significance level of each delay time was evaluated with a one-way ANOVA(p<0.05). In the visual test, score levels on 30 seconds delay time was a little bit higher than others(p<0.05). The signal intensity of the tumor were $1445{\pm}360$, $1410{\pm}320$, $1510{\pm}415$ on immediately, 20 seconds, and 30 seconds and score levels were $4.18{\pm}0.85$, $3.54{\pm}0.94$, $4.45{\pm}0.74$(p<0.05). The data on immediate images showed better results than that others(p<0.05). Conclusively, Although it has been high scored in 30sec delay time for visual test in order to avoid failure in 20second, 30seconds delay time after contrast media administration, we recommend that the DCE 3D breast MRI commence immediately.

• 한국자동차공학회논문집
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• 제23권4호
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• pp.444-453
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• 2015

In the previous study, several problems were observed in a NG conversion vehicle, which were fail of air-fuel ratio closed loop control, aggravated fuel economy, increased harmful emission and declined roadability. It was provisionally supposed that the mismatch of injection system with the engine caused these performance deterioration. In this context, the characteristics of fuel injection system of commercial conversion kit for NG were investigated experimentally varying the engine speed, fuel rail pressure and volume. The results are as follows; The injection quantity decreases as the engine speed increases due to the extremely small rail volume of the presenting system and flow rate of No. 2 injector are always lower than that of the other ones regardless of the speed under the dynamic operation condition. Furthermore the existing system does not meet the required fuel quantity for the normal engine operation over 3000 RPM. On the other hands, the large rail volume systems ease and/or eliminate the difference of injection quantity between the injectors according to the speed variation, however, these systems decrease injection flow rate and still cannot supply sufficient fuel. Finally, suitable combination of the higher rail pressure and the larger rail volume might be a solution about these problems.