• Title/Summary/Keyword: inherent safety

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Perforator-based Fasciocutaneous Rotation Flap (천공지를 이용한 근막회전피판)

  • Ahn, Hee Chang;Kim, Youn Hwan;Sung, Kun Yong
    • Archives of Plastic Surgery
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    • v.33 no.2
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    • pp.181-186
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    • 2006
  • Myocutaneous flaps have improved the management of soft tissue defects on buttocks and lower extremity. However, there are several inherent disadvantages of muscle flaps such as functional deficits of the donor sites and the bulkiness at the recipient site. To overcome these disadvantages, we have used perforator-based fasciocutaneous rotation flaps for reconstruction of the buttock and lower extremity defects. From March 2003 to February 2005, we have treated 14 patients using perforator-based fasciocutaneous rotation flaps. 10 flaps were based on perforators of the gluteus maximus muscle, and 4 flaps were nourished by perforators from the tibialis anterior and posterior system. The mean postoperative follow-up period was about 1 year. The technique involves localization of the flap perforators preoperatively with a Doppler. The flaps were elevated superficial to the fascia with preservation of one to three perforators. The donor site is then closed primarily. All flaps completely survived and there was no perioperative complications. There was no functional disability of the donor area with esthetically pleasing results. Perforator-based fasciocutaneous rotation flaps for the reconstruction of buttock and lower extremity defects are excellent alternatives to musculocutaeous flaps. The vascularity of the flaps is robust and dissection is technically easy. Perforator flaps do not require sacrificing muscles, but provide sufficient volume and are durable Furthermore, these flaps result in less scar formation and allow more liberal dissection with safety. We conclude that perforator-based fasciocutaneous rotation flaps are very useful for reconstruction of the buttock and lower extremity.

Investigation on Adhesion Control Standards and Skin Adverse Effects of Skin Attached Formulations (파스제의 점착력 관리기준 및 피부 부작용 조사연구)

  • Kim, Ji Yeon;Kim, Kwang Joon;Park, Sang-Wook;Bang, Joon Seok;Lee, Wonjae
    • Korean Journal of Clinical Pharmacy
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    • v.24 no.3
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    • pp.219-228
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    • 2014
  • Objectives: This paper was aimed to investigate the adhesion control standards of pain relieving patch (PRP) drugs and to survey it's adverse effects on the skin of patients for safe use of PRP drugs. Methods: In this study, the related documents of PRP drugs of Korea pharmacopoeia (KP), United States pharmacopoeia (USP), Japanese Pharmacopoeia (JP), European pharmacopoeia (EP), and information web sites of the Ministry of Food and Drug Safety (MFDS) were surveyed. Also, the past and current labeling of PRP drugs marketed in the pharmacy was investigated and compared. Results: In KP and JP, the lower limit standard for PRP's adhesion control is established, but the upper limit standard is not designated. In USP and EP, neither the lower nor upper limit standard is established. The main reasons of skin adverse effects are considered as inherent adverse reactions of the applied drugs for PRP. Another reason is involved in patient's medication mistakes related to PRP's adhesion control, respiratory depression of skin according to physical skin closure, and microbial growth, etc. Conclusion: For safe use of PRP drugs, we proposed ensured guidelines like additional instructions of pharmacist's prescription and detailed labeling systems for usage of PRP drugs applied on skin.

A Study on Characteristics of Street Furniture Design in Modern Public Space (현대 공공공간의 스트리트 퍼니처 디자인 특성에 관한 연구)

  • Hwang, Mee-Young
    • Korean Institute of Interior Design Journal
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    • v.20 no.4
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    • pp.191-200
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    • 2011
  • Street furniture such as benches, streetlamps, and shades which are easily accessible in cities has contributed to the promotion of active, lively environment for people living in cities. Furthermore, they make the characteristics of specific regions and cities, and are valued as a communication interface to restore the relationships between people and cities. The street furniture design with inherent publicness is an essential element for leisurely life and refined image of modern people who have experienced severance and mental poverty in uniform, vertical modern city space with the development of advanced science and technology. The purpose of this study is to analyze the new design approaches to street furniture which plays an important role in the determination of the images of modern city environment and to examine the characteristics and trends of such designs. First, in accordance with the flow of studies from publicness and public space to street furniture, the concept and meaning of publicness which is the basic element of public space were identified through theoretical examination, and the characteristics and roles of modern public space were analyzed through literature review, data review, and international cases. Based on the results of this theoretical analysis, the concept and meaning elements, function elements, and design elements of the street furniture which was planned in accordance with the goal and functions of public space were identified. For the meaning elements of street furniture design, fun, health, culture, sustainability, and vitalization were identified. For the function elements of street furniture design, convenience, safety, and delivery were identified. As the characteristics of modern street furniture design, convergent, green, digilog, functional, and universal designs were analyzed. This study is meaningful in that it recognized the roles of street furniture in modern public space as a concrete, practical environmental design element and estimated the development directions of street furniture design in public space.

18-FDG EXTERNAL RADIATION DOSE RATES IN DIFFERENT BODY REGIONS OF PET-MRI PATIENTS

  • Han, Eunok;Kim, Ssangtae
    • Journal of Radiation Protection and Research
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    • v.38 no.3
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    • pp.157-165
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    • 2013
  • To determine the factors affecting the external radiation dose rates of patients undergoing PET-MRI examinations and to assess the trends of these differences, we measured the changes in the dose rates of $^{18}F$-FDG during a set period of time for each body region. Consistent with theoretical predictions, the dose rate decreased over time in patients undergoing PET-MRI examinations. Furthermore, immediately after the $^{18}F$-FDG injection, the dose rate in the chest region was the highest, followed by the abdominal region, the head region, and the foot region. The dose rate decreased drastically as time passed, by 2.47-fold, from $339.23{\pm}74.70mSv\;h^{-1}$ ($6.73{\pm}5.79$ min) at the time point immediately after the $^{18}F$-FDG injection to $102.71{\pm}26.17mSv\;h^{-1}$ ($136.11{\pm}25.64$ min) after the examination. In the foot region, there were no significant changes over time, from $32.05{\pm}20.23mSv\;h^{-1}$ ($6.73{\pm}5.79$ min) at the time point immediately after the $^{18}F$-FDG injection, to $23.89{\pm}9.14mSv\;h^{-1}$ ($136.11{\pm}25.64$ min) after the examination. The dose rate is dependent on the individual characteristics of the patient, and differed depending on the body region and time point. However, the dose rates were higher in patients who had a lower body weight, shorter stature, fewer urinations, lower fluid intake, and history of diabetes mellitus. To decrease radiation exposure, it is difficult or impossible to change factors inherent to the patient, such as sex, age, height, body weight, obesity, and history of diabetes mellitus. However, factors which can be changed, such as the $^{18}F$-FDG dose, fasting time, fluid intake, number of urinations, and contrast agent dose can be controlled to minimize the external radiation exposure of the patient.

Magneto-rheological and passive damper combinations for seismic mitigation of building structures

  • Karunaratne, Nivithigala P.K.V.;Thambiratnam, David P.;Perera, Nimal J.
    • Earthquakes and Structures
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    • v.11 no.6
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    • pp.1001-1025
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    • 2016
  • Building structures generally have inherent low damping capability and hence are vulnerable to seismic excitations. Control devices therefore play a useful role in providing safety to building structures subject to seismic events. In recent years semi-active dampers have gained considerable attention as structural control devices in the building construction industry. Magneto-rheological (MR) damper, a type of semi-active damper has proven to be effective in seismic mitigation of building structures. MR dampers contain a controllable MR fluid whose rheological properties vary rapidly with the applied magnetic field. Although some research has been carried out on the use of MR dampers in building structures, optimal design of MR damper and combined use of MR and passive dampers for real scale buildings has hardly been investigated. This paper investigates the use of MR dampers and incorporating MR-passive damper combinations in building structures in order to achieve acceptable levels of seismic performance. In order to do so, it first develops the MR damper model by integrating control algorithms commonly used in MR damper modelling. The developed MR damper is then integrated in to the seismically excited structure as a time domain function. Linear and nonlinear structure models are evaluated in real time scenarios. Analyses are conducted to investigate the influence of location and number of devices on the seismic performance of the building structure. The findings of this paper provide information towards the design and construction of earthquake safe buildings with optimally employed MR dampers and MR-passive damper combinations.

An Experimental Study On the Course-Keeping of an 8,000 DWT Barge ship (재화중량 8, 000 톤급 Barge선의 침로안정성에 대한 실험적 연구)

  • Chun, H.H.;Kwon, S.H.;Ha, D.D.;Ha, S.U.
    • Journal of the Society of Naval Architects of Korea
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    • v.34 no.4
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    • pp.1-11
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    • 1997
  • When a barge is towed by a tug boat using a tow line, the barge is frequently subject to a large sway motion induced from its inherent yaw motions. This large sway motion combined with external forces due to winds and waves may makes the towing to be difficult or even dangerous. It has been reported that in worse situations, barges or tugs are capsized. In addition, the large sway motion of the towed barge gives a menace to the safety of ships navigating nearby. This paper is the results of the experimental investigation into the course stability of an 8,000 DWT barge using a Towing Tank and a Circulating Water Channel. Various skegs are designed and course stability tests for the barge with skegs are conducted in calm water and in irregular waves. It is observed that an effective skeg attached to the barge enables the sway motion to be zero while the sway amplitude of the bare hull is around 10 times its breadth.

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Development of Micro Tensile Test of CVD-SiC coating Layer for TRISO Nuclear Fuel Particles at elevated temperature

  • Lee, Hyun-Min;Park, Kwi-Il;Kim, Do-Kyung
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2012.05a
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    • pp.95.1-95.1
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    • 2012
  • Very High Temperature gas cooler Reactor (VHTR) has been considered as one of the most promising nuclear reactor because of many advantages including high inherent safety to avoid environmental pollution, high thermal efficiency and the role of secondary energy source. The TRISO coated fuel particles used in VHTR are composed of 4 layers as OPyC, SiC, IPyC and buffer PyC. The significance of CVD-SiC coatings used in tri-isotropic(TRISO) nuclear coated fuel particles is to maintain the strength of the whole particle. Various methods have been proposed to evaluate the mechanical properties of CVD-SiC film at room temperature. However, few works have been attempted to characterize properties of CVD-SiC film at high temperature. In this study, micro tensile system was newly developed for mechanical characterization of SiC thin film at elevated temperature. Two kinds of CVD-SiC films were prepared for micro tensile test. SiC-A had [111]-preferred orientation, while SiC-B had [220]-preferred orientation. The free silicon was co-deposited in SiC-B coating layer. The fracture strength of two different CVD-SiC films was characterized up to $1000^{\circ}C$.The strength of SiC-B film decreased with temperature. This result can be explained by free silicon, observed in SiC-B along the columnar boundaries by TEM. The presence of free silicon causes strength degradation. Also, larger Weibull-modulus was measured. The new method can be used for thin film material at high temperature.

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Cytotoxicity of Ultra-pure TiO2 and ZnO Nanoparticles Generated by Laser Ablation

  • Jeong, Minju;Park, Jeong Min;Lee, Eun Jeong;Cho, Yea Seul;Lee, Chunghyun;Kim, Jeong Moo;Hah, Sang Soo
    • Bulletin of the Korean Chemical Society
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    • v.34 no.11
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    • pp.3301-3306
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    • 2013
  • This paper aims to address the cellular toxicity of ultra-pure titanium dioxide ($TiO_2$) and zinc oxide (ZnO) nanoparticles (NPs) frequently employed in sunscreens as inorganic physical sun blockers to provide protection against adverse effects of ultraviolet (UV) radiation including UVB (290-320 nm) and UVA (320-400 nm). In consideration that the production and the use of inorganic NPs have aroused many concerns and controversies regarding their safety and toxicity and that microsized $TiO_2$ and ZnO have been increasingly replaced by $TiO_2$ and ZnO NPs (< 100 nm), it is very important to directly investigate a main problem related to the intrinsic/inherent toxicity of these NPs and/or their incompatibility with biological objects. In the present study, we took advantage of the laser-assisted method called laser ablation for generation of $TiO_2$ and ZnO NPs. NPs were prepared through a physical process of irradiating solid targets in liquid phase, enabling verification of the toxicity of ultra-pure NPs with nascent surfaces free from any contamination. Our results show that $TiO_2$ NPs are essentially non-poisonous and ZnO NPs are more toxic than $TiO_2$ NPs based on the cell viability assays.

Structural Restoration for the Electric Power Transmission Tower Damaged by Foundation Settlements (기초침하에 의해 손상된 송전철탑 구조물의 구조성능개선)

  • Lee, Ho Beom;Park, Jong Kwon;Kim, Il Soo;Jang, Il Young;Song, Jae Ho
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.17 no.2
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    • pp.83-93
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    • 2013
  • Generally the capacities of electric power transmission tower's members are improved by increasing their stiffness nature through injection of grout or attachment of other structural stiffeners. Those are for upgrading their axial strength by fulfillment of proper materials into pipe members, increment of member dimension by addition of section, or a combination of the two. However the use of innovative and unusual procedures would be positively recommended for getting more stable state. It is that buckled members are replaced with lengthened and strengthened members. In providing the structural restoration procedures for the existing electric power transform tower whose main members have been damaged due to unequal foundation settlement, structural damage inspection works and numerical analyses for the damaged one and the restored one were done in detail at first. secondarily member-exchanging works using a newly-generated jacking system and strengthened members were achieved. This figures are to point clearly to inherent advantages attending the management of the towers.

Performance Comparison of Space-Time Block Coding in High-speed Railway Channel (고속 철도 채널 환경에서 시공간 블록 부호 성능 비교)

  • Park, Seong-Guen;Lee, Jong-Woo;Jeon, Taehyun
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39C no.3
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    • pp.291-297
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    • 2014
  • Due to the rapid increase in demand for transportation of human and freight in modern railway systems, the CBTC system has been proposed, which is the solution for improvement of the line capacity that has been limited by the conventional track circuit based train control system. In the CBTC system, higher reliability of the communication system should be guaranteed for the safety of passengers and trains. However, due to the inherent characteristics of the wireless channel environment, performance degradations are inevitable. The diversity techniques can increase the reliability of data transmission using multiple antennas. In this paper, we investigate the performance of the STBC in the railway channel environment. Rician fading model is used for the viaduct scenarios which take important roles in the railway system. Also, considered is the Doppler effect which is an important factor in the mobile communication system. Simulations are performed to analyze the performance of the STBC in various channel environments. Results show that the performance degradation due to the phase error in viaduct scenarios is independent of the diversity order but is affected by the constellation of the modulation.