• Molecules and Cells
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• v.26 no.6
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• pp.576-582
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• 2008

Nervous system development takes place after positional information has been established along the dorsal-ventral (D/V) axis. The initial subdivision provided by a gradient of nuclear dorsal protein is maintained by the zygotic genes expressed along the D/V axis. In this study, an investigation was conducted to determine the range of Dpp function in repressing the expression of eagle (eg) that is present in intermediate neuroblasts defective (ind) and muscle specific homeobox (msh) gene domain. eg is expressed in neuroblast (NB) 2-4, 3-3 and 6-4 of the msh domain, and NB7-3 of the ind domain at the embryonic stage 11. In decapentaplegic (dpp) loss-of-function mutant embryos, eg was ectopically expressed in the dorsal region, while in dpp gain-of-function mutants produced by sog or sca-GAL4/UAS-dpp, eg was repressed by Dpp. It is worthy of note that Dpp produced from sim;;dpp embryos showed that Dpp could function at long range. However, Dpp produced from en-GAL4/UAS-dpp or wg-GAL4/UAS-dpp primarily acted at short-range. This result demonstrated that this discrepancy seems to be due to the repression of Dpp to EGFR signaling in sim;;dpp embryos. Taken together, these results suggest that Dpp signaling works at short-range, but can function indirectly at long-range by way of repression of EGFR signaling during embryonic neurogenesis.

• Archives of design research
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• v.9
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• pp.701-712
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• 1994

We are in the process of the deepening of the informationalized society. Such a phenomenon(of deepening of the informationalized society) means that human being is surrounded by a linguistic or semiological environment instead of realistic experience. And it is concerned with the visual design composed by the visual languages and semiotics of Arts. Because the visual design is a kind of the linguisticsmion using the visual formation. This penomena necessarily brings the expansion of the quatity of information and accompanies the simplification of messages. Therefore when we apply the simplicity resulting from the ideality of KYEORE painting(the folk Art of Korea), it can be cotribute to those who should be in the center of semiological environment more deeply as a source to maximize the effect of communication, which is the conclusion of this study. In sort, the characteristics of our KYEORE painting is the ideal expression. There are found not a few problems such as the depiction of forms, the perspective representation, the chiaroscuro, the expression of material if we evaluate them from the western formative viewpoint. But the depiction of the fact is less direct than the ideal expression itself, is likely to be much complicated, and can be far away from the world of reality. Because it is just the first step for satisfying the ideal images in man. In the composition of KYEORE painting is dominated by the rules nonprescription of time amd place, colloquialism of the meaning, distinction maximization. They are all the compositive characteristics resulting from the ideality. If these characteristics are modulated intelligently to the current thoughts, they will help to build the new visual communication system of Korea which has more direct and fast absorption force.

• The Korean Journal of Applied Statistics
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• v.21 no.6
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• pp.911-921
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• 2008

Visualization of the gene expression data on a low-dimensional graph is helpful in uncovering biological information contained in the data. In this study, we focus on two modified versions of the parallel coordinate plot. First one is the ePCP(enhanced parallel coordinate plot) which shows "near smooth" connecting curves between axes spaced proportionately to the proximity of re-ordered variables. Second one is APCP(Andrews' type parallel coordinate plot) which is obtained by rotating Andrews' plot that has a form of the parallel coordinate plot. Visualization procdures using ePCP and APCP are given for the lymphoma data case.

• Journal of the Korean Society of Clothing and Textiles
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• v.39 no.2
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• pp.257-270
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• 2015

This study investigates the effect of perceived value on attitude and purchase intention of upcycling fashion goods. The study also examines the effect of perceived value on attitudes according to fashion innovativeness. The qualitative data analysis results from NVivo 10.0 showed that consumers paid attention to the creative design value, environmental value, scarcity value of upcycling fashion goods. Next, 201 effective questionnaires were analyzed using SPSS 22.0 and AMOS 20.0. The results are as follows. First, there were 5 factor solutions for the perceived value of up-cycling fashion goods: environmental value, creative design value, functional value, emotional value, and self-expression value. Second, environmental value, functional value, and self-expression value positively affected attitude; however, creative design value and emotional value did not affect attitude. Third, attitude positively influenced purchase intention of upcycling fashion goods. Fourth, there was a significant difference in the magnitude of the effect of self-expression value on attitude according to fashion innovativeness. The results of this study provide useful information for marketers or managers interested in upcycling fashion goods.

• Fisheries and Aquatic Sciences
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• v.21 no.2
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• pp.4.1-4.5
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• 2018

Insulin-like growth factors (IGFs), along with IGF-binding protein and IGF receptor, are well-known regulators in the growth and survival of vertebrates. In this study, we investigated the involvement of IGFs and protein variation during embryonic development of the olive flounder (Paralichthys olivaceus). Morphological stages were divided into six main developments as blastula, gastrula, cephalization, cranial regionalization, tail lift, and hatch. During embryonic development, protein variation was investigated using sodium dodecyl sulfate-polyacrylamide gel electrophoresis and electrospray ionization quadrupole time-of-flight mass spectrometry/mass spectrometry. In addition, the mechanism of signaling of IGF-I receptor was examined using immuno-blot analysis. We found marked changes in protein expression at four stages of embryonic development and identified proteins as belonging to the vitellogenin 2 family. As development progresses, expression of IGF-II, phosphotyrosine, and phospho-Akt increased, while expression of growth factor receptor-bound protein 2 (GRB2) and one of guanine-nucleotide-binding proteins (Ras) decreased. These results provide basic information on the IGF system in the embryonic development of the olive flounder.

• Animal cells and systems
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• v.7 no.3
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• pp.265-269
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• 2003

Vascular endothelial growth factor (VEGF) is a potent regulator of normal and abnormal angiogenesis. Recent literature suggests that VEGF has several activities that may amplify acute inflammation reactions. Dysregulated VEGF expression has been implicated as a major contributor to the development of a number of common disease pathologies. One of common mutations in the 3'- untranslated region of the VEGF gene, a C\longrightarrowT exchange at nucleotide position 936, has been found to be significantly associated with VEGF expression levels in the plasma from a previous Austrian study. The frequency of this mutation could be important genetic information regarding tumor growth and angiogenesis related diseases. The aim of this study was to investigate the frequency distribution of this mutation in general Korean population. We examined the statistical data from 207 healthy Korean subjects. Observed numbers (%) of 936T were 28.5 (CT) and 3.9 (TT), respectively. The mutant allele frequency of 936T in Korean subjects was 0.18, which appeared somewhat higher than that in Austrian subjects.

• Journal of the Korean Institute of Intelligent Systems
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• v.18 no.2
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• pp.278-283
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• 2008

As the usefulness of internet is kept changing more productively with web 1.0, web 2.0 usage of XML is also increasing very rapidly. In XML environment the most critical function is the ability of effective retrieval of useful information from XML repository. That makes the W3C XQuery more popular XQuery has very complicated structure as a query language due to the semi_structured nature of XML. FLOWOR, which stand for, let. where, order by, return, is the most commonly used expression in XQuery. In this paper we suggest the methods to handle XQuery FLWOR on relational environments. We also analyze and evaluate our approach to prove its correctness.

• Genomics & Informatics
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• v.9 no.1
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• pp.19-27
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• 2011

Gene Expression Omnibus (GEO) has kept the largest amount of gene-expression microarray data that have grown exponentially. Microarray data in GEO have been generated in many different formats and often lack standardized annotation and documentation. It is hard to know if preprocessing has been applied to a dataset or not and in what way. Standard-based integration of heterogeneous data formats and metadata is necessary for comprehensive data query, analysis and mining. We attempted to integrate the heterogeneous microarray data in GEO based on Minimum Information About a Microarray Experiment (MIAME) standard. We unified the data fields of GEO Data table and mapped the attributes of GEO metadata into MIAME elements. We also discriminated non-preprocessed raw datasets from others and processed ones by using a two-step classification method. Most of the procedures were developed as semi-automated algorithms with some degree of text mining techniques. We localized 2,967 Platforms, 4,867 Series and 103,590 Samples with covering 279 organisms, integrated them into a standard-based relational schema and developed a comprehensive query interface to extract. Our tool, GEOQuest is available at http://www.snubi.org/software/GEOQuest/.

• BMB Reports
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• v.41 no.12
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• pp.863-867
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• 2008

CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. Although CD320 is known to enhance proliferation of germinal center (GC) B cells, little other information is available. In this study, we investigated its cellular distribution in the GC. Confocal microscopy of human tonsil sections revealed co-localization of CD320 with CD19 and CD38 but not with CD3 indicating that GC B cells expressed CD320 in addition to FDC. In purified GC B cells, CD320 expression was inhibited in the nucleus, membrane and cytoplasm. Reverse transcriptase-polymerase chain reaction confirmed CD320 mRNA expression in B cells. These finding indicate that CD320 is expressed in B cells in addition to FDC, and that its GC activity may be more complicated than previously thought.

• Fashion & Textile Research Journal
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• v.15 no.5
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• pp.671-681
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• 2013

Persona means the mask of personality where the internal ego exposes itself to the outside. The complicated structure and diversity of contemporary society has provided men with a more variegated and diversified persona; in addition, advancements in internet and information communications creates the possibility for the emergence of more variegated and new persona. This study probes the persona of virtual space expressed in fashion designs; subsequently, this study reviews the concept and various characteristics of persona and examines the type of persona in the virtual space from the perspective of the manifestation of identity. The type of persona in the virtual space canbe categorized into flexible identity and falsified identity; subsequently, the characteristics and meanings of virtual space persona in fashion designs are analyzed. Flexible identity-oriented personas expressed in fashion designs are revealed through the images of animals or dolls. This is a childlike persona expression that expresses ego through other substances in an effort to express infantile substances such as dreams and fantasy cherished in childhood. Falsified identity-oriented personas are expanded as a realm of expression of the body and the realities are camouflaged as transformed persona. Negating existence itself by covering the eyes or face as well as the concealment of the body with masks or veils is an expression of a self-denying persona.