• Proceedings of the Korean Society of Life Science Conference
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• 2007.10a
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• pp.56.1-56.1
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• 2007

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• Journal of the Korean Society of Food Science and Nutrition
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• v.37 no.9
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• pp.1214-1221
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• 2008

The aim of this study is to propose suggestions for establishing Korean regulatory standards of infant formula. Accordingly, the regulatory standards for food contaminants and additives in Korean infant formulas were compared and analyzed with those in CODEX, EU, Australia and New Zealand. Several suggestions for regulations were found from different countries. Firstly, it is advisable that additives for nutrient supplement of infant formula be classified as types of nutrients. Secondly, it is proposed that guidelines should be set on the maximum amount of additives in infant formula. Thirdly, pathogens such as Staphylococci and Salmonella of infant formula should be regulated. Finally, present regulations need to establish the maximum permissible levels of some pesticides, Pb and Al, that other countries are already regulating. These proposed recommendations would broaden the scope of infant formula regulatory standards needed for infants' health.

• Food Science of Animal Resources
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• v.34 no.6
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• pp.749-756
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• 2014

A rapid and simple analytical method for L-carnitine was developed for infant and toddler formulas by liquid chromatography tandem mass spectrometry (LC-MS/MS). A 0.3 g of infant formula and toddler formula sample was mixed in a 50 mL conical tube with 9 mL water and 1 mL 0.1 M hydrochloric acid (HCl) to chemical extraction. Then, chloroform was used for removing a lipid fraction. After centrifuged, L-carnitine was separated and quantified using LC-MS/MS with electrospray ionization (ESI) mode. The precursor ion for L-carnitine was m/z 162, and product ions were m/z 103 (quantitative) and m/z 85 (qualitative), respectively. The results for spiked recovery test were in the range of 93.18-95.64% and the result for certified reference material (SRM 1849a) was within the range of the certificated values. This method could be implemented in many laboratories that require time and labor saving.

• Journal of Dairy Science and Biotechnology
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• v.25 no.1
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• pp.55-60
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• 2007

Contents of scorched particles in infant formula were studied to provide a scientific evidence for standardization of Food Regulation in Korea. The specification of scorched particles in infant formula in Korea was satisfied with CODEX, USDA and so on. But food regulations for scorched particles in baby food are not mentioned in Korea. Nowadays social interests of scorched particles in infant formula are being increased in the respect of safety for baby food. The composition and contents of scorched particles were analyzed with Scanning Electron Microscope-Energy Dispersive X-ray Spectrometer(SEM-EDS) and Inductively Coupled Plasma Mass Spectrometer(ICP-MS). The results indicate that the scorched particles consist Ca, Na, Fe, Mg and trace elements derived from the ingredient of infant formula. Infant formula are composed of milk, skimmed milk, whey, mixed vegetable oils, minerals and vitamins. These results also show that the contents of scorched particles of infant formula in Korea are little or similar level to those reported in other countries. In general, heavy metals derived from scorched particle are originally used as a source of minerals in infant formula. And it has been thought that they doesn't effect on Provisional Tolerable Weekly Intake set by FAO/WHO for contents and composition of scorched particles.

• The Korean Journal of Food And Nutrition
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• v.19 no.4
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• pp.539-551
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• 2006

This study was to investigate the nutrient intakes from infant formula and supplemental foods of 129 infants(boys 69, girls 60) fed formula, aged from 5 to 12 months. Subjects were divided into $5{\sim}6\;months,\;7{\sim}8\;months,\;9{\sim}10\;months,\;and\;11{\sim}12\;months$ by ages. Dietary assessment was carried out by using 24-hour-recall method. The average intakes and feeding frequency of infant formula were $702m{\ell}$, 4.4 times in boys and $815m{\ell}$, 4.8 times in girls, respectively. Supplemental foods were introduced at the age of $4{\sim}6\;months$ in 86% of the infants. Foods introduced first as the supplemental food were rice gruel soup, commercial weaning foods, fruit juice. Energy intakes were similar to RDA. Daily intakes of calcium at all age groups were higher than the RDA, therefore, calciun overnutrition were elucidated. Average intakes of protein, phosphorus, iron, zinc, vitamin A, vitamin $B_1,\;vitamin\;B_2$, niacin, vitamin $B_6$, vitamin C were above RDA, folate did not meet RDA of infants at all ages. In conclusion, the average status of nutrient intakes of infants was fairly good, however, nutrient intakes from supplemental foods were lower in girls than in boys of $10{\sim}12$months, and folate status seemed to be poor. Therefore, mothers feeding infant formula to their infants should be educated for the importance of supplemental foods and its practice to support good nutrition.

• Journal of Nutrition and Health
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• v.18 no.1
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• pp.46-54
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• 1985

Three types of infant food were experimentally prepared based on the average caloric requirement for, Koreans : Formula A, with 1/3 RDA for 4-6 month, formula B, with 1/2 RDA for 7-9 month, and formula C, with 2/3 RDA for 10-12 month old infants. Into each formula was added approximately 50% of rice. Analysis of the nutritive values on these formula showed no deviance Com the expected values in case of general nutrients while the percent of essential amino acids in protein was muck higher except methionine. Since iron content was found to be below the half of except values, a sufficient amount of iron as required in RDA should be additionally supplied, for example, in iron drops. The infant preference test on each formula showed much favorable acceptability : 50% of them responded as moderate, 33.3% as favorable, 12.5% as disliking, and 4.2% as disgusting. The test also showed no noticeable change in both feces and appetite.

• Journal of Nutrition and Health
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• v.19 no.1
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• pp.3-15
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• 1986

This study was intended to investigate the rheological properties of the development formula of infant foods and the results are summarized as follow ; 1) Consistency of starch solutions measured by Brabender Anylograph and Brookfield viscometer showed that waxy rice and riece with malt had lower consistency and more rheological stability.The flow type of tested raw materials and formula was found to ？ pseudoplastic, as judged by n-value of 0.332 -0.692, and no yield value. 2) The influenced of temperature on consistency could be accounted for by the equation, In (n) = K(1/T) + const. this relationship indicated that consistency of tested sample increased as temperature decreased. The consistency of waxy rice, rice with malt and formula A were less affected by the temperature change. 3) Infant foods with malt(formula A ) ad with waxy rice maintained better freeze-thaw stability in terms of consistency and starch aggregation indicating that this infant food could be stored for a long term in the freezer section of the home refrigeratory without adverse effect on the product quality. 4) From the above experiments, it would necessarily follow that infant food can be easily made at home the food-stuffs generally available around us, and that the easiest and safest way to store them lies in making them into semisolid state, and in keeping them in frozen state.

• Food Science of Animal Resources
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• v.33 no.5
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• pp.617-625
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• 2013

The present study was carried out to assess dietary exposure and risk for the infant population by lead (Pb), cadmium (Cd), and arsenic (As) exposure through modified milk powder and formulas. Analysis of heavy metals was performed using a microwave device and inductively coupled plasma-mass spectrometry, the method for which was fully validated. Various samples (n=204), including modified milk powder, modified milk, follow-up modified milk powder, infant formula and follow- up formula, were collected from retail outlets and markets across Korea. The mean contents of heavy metals were Pb 0.0004 (modified milk)-0.010 (infant formula) mg/kg, Cd 0.002 (modified milk)-0.007 (follow-up formula) mg/kg, and As 0.004(modified milk)-0.040 (infant formula) mg/kg, respectively. For risk assessment, daily intakes of heavy metals through maximum intake of modified milk powder and formulas were calculated and compared with reference doses established by JECFA and WHO. The dietary exposures of heavy metals were $0.78-1.04{\mu}g$ Pb/d, $0.65-0.87{\mu}g$ Cd/d, and $2.25-3.00{\mu}g$ As/d, corresponding to 2.0-4.5%, 7.1-16.0%, and 0.4-0.9% of reference doses, respectively. Therefore, the level of overall dietary exposure to heavy metals for Korean infant through food intake was below 20% of the reference dose, indicating a low risk to infant consumers.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.5
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• pp.569-577
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• 2007

The purpose of the present study was to propose some amendments on nutrient standard regulations of infant formula in Korea. For this purpose, we compared and analyzed the nutrient regulations of Korea, CODEX, U.S.A, Japan, EU, Australia and New Zealand. Some developing aspects of Korea's nutrient standard regulations for infant formula need to be examined as follows: firstly, both milk-based formula and soy-based formula standards would be unified into an infant formula, and the user of infant formula would be categorized for babies less than 6 month old. Secondly, nitrogen conversion factor of milk protein in the infant formula would be 6.38, which is the same as that of CODEX Revised Standard. Protein quantities could be differentiated by protein sources, and essential amino acids in human milk would be standardized according to protein contents. Thirdly, $\alpha$-linolenic acid, docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA) as essential fatty acids and trans fatty acid would be standardized in terms of the contents. Fourthly, it is recommended that the unit of vitamins and minerals would be changed from g/100 g to g/100 kcal, and individual vitamins and mineral would have their maximum values. Finally, 5 nucleotides (cytidine, uridine, adenosine, guanosine, inosine 5'-monophosphate) and fluoride would be required for the strengthening the immunity and the development of teeth, respectively. In conclusion, the scientific studies on amendment scheme of nutrient standard regulations of infant formula is very important to fortify nutritional completeness for Korean infants and young children.

• Korean Journal of Food Science and Technology
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• v.45 no.2
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• pp.235-240
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• 2013

To analyze aflatoxin $M_1$ ($AFM_1$), we dissolved infant formula in warm water and cleaned it by using an immunoaffinity column (IAC). The amount of $AFM_1$ was determined by high-performance liquid chromatography coupled with fluorescence detection. $AFM_1$ was detected in 281 of 439 samples. Thus, the detection rate of $AFM_1$ was 64.0%. The average concentration of $AFM_1$ in positive samples was 2.6 ng/kg (of prepared formula). The estimated daily intake (EDI) of $AFM_1$ through infant formula was 0.087-0.646 ng/kg body weight/day and the additional number of cases of liver cancer associated with exposure to $AFM_1$ would be 0.003-0.020 cancer cases/1,000,000. Because there is less than 1 cancer case/1,000,000 per year, the exposure to $AFM_1$ through infant formula in Korea is considered to be an unlikely human health concern.