• Title/Summary/Keyword: induction period

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Efficacy of Modified Rush Allergen-Specific Immunotherapy on Canine Atopic Dermatitis

  • Lee, Wang-Hui;Park, Seong-Jun
    • 한국임상수의학회지
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    • 제34권4호
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    • pp.245-248
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    • 2017
  • Modified rush ASIT protocol has been performed to identify the ideal schedule that allows the dose considered effective to be reached in the shortest possible time with the fewest adverse effects. Ten atopic dogs of this study includes fulfillment of Favrot's criteria. Offending allergens were identified by the use of IDST. During the induction period, the dogs were received a total of 15 injections. Ten injections were administrated every 30 minutes in a day with gradually increasing amounts and concentrations of allergens, and the last 5 injections were administered every 3 days. Disease severity was quantified by using the canine atopic dermatitis extent and severity index (CADESI). During induction period, reduction rate from baseline scores varied between 1% and 67% and the improvement of ${\geq}50%$ was recorded after induction period of therapy for CADESI-03 score in 6 of the 10 dogs. This study of ten dogs with atopic dermatitis provide evidence for the efficacy and safety of modified rush ASIT for clinical improvement.

대용량 유도기 기동 특성 모델링 및 전략적 기동 방법에 관한 연구 (Modeling and Strategic Startup Scheme for Large-Scaled Induction Motors)

  • 정원욱;신동열;이학주;윤기갑
    • 한국산학기술학회논문지
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    • 제8권4호
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    • pp.748-757
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    • 2007
  • 본 논문은 대용량 유도전동기가 기동할 때 발생하는 큰 돌입전류로 인해 PCC(Point of Common Coupling)에 심한 전압 강하가 발생하게 되어 기동에 실패하는 문제를 해결하기 위해 대상 유도전동기의 기동 특성과 배전계통을 모델링하고 시뮬레이션을 수행함으로써 유도기 기동시에 전압저하 현상을 해석하였다. 문제가 되는 유도전동기는 2500KVA 용량의 펌프용 농형 유도전동기로 리액터 기동법을 채용하고 있다. 2500KVA 유도전동기 한대의 기동에는 문제가 없으나 기동 완료 후 PCC 전압이 다소 떨어진다. 하지만 추가로 동일 용량의 유도전동기가 기동하게 되면 PCC의 심한 전압강하로 기동에 실패하게 되는 문제가 발생하였다. 이러한 문제 해결을 위해 본 논문에서는 실제 기기의 기동시 토크-속도 곡선을 이용한 유도전동기의 기동 특성을 정확히 모델링하고 시뮬레이션을 수행하여 두 대의 대용량 유도전동기가 순차적으로 기동에 성공할 수 있는 적절한 전압보상 방안을 제안하였다. 본 논문에서 논의되는 대용량 유도전동기는 한국수자원공사의 취수장에서 운전되고 있으며 대상 유도전동기 및 배전계통은 PSCAD/EMTDC 소프트웨어를 사용하여 모델링 및 시뮬레이션을 수행하였다.

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대추 메탄올 추출물의 페놀성 화합물 함량과 항산화 효능 (Antioxidative Capacity and Total Phenolic Compounds of Methanol Extract from Zizyphus jujuba)

  • 김효경;주광지
    • 한국식품영양과학회지
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    • 제34권6호
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    • pp.750-754
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    • 2005
  • 대추의 페놀화합물 함량과 항산화 효능을 알아보기 위하여 특초(大棗: 대조), 상초(中棗: 중조), 약초(小棗: 소조) 세 종류의 대추를 메탄올에 추출한 용액과 물에 침 지한 후 메탄올로 추출한 용액을 동결 건조하여 총 페놀화합물 함량, 전자공여능, 산패유도기간을 측정하였다. 대추의 총 페놀화합 물 함량은 메탄올에 추출한 약초, 상초, 특초가 각각 $326.46\;mg\%,\;223.13\;mg\%,\;158.06\;mg\%$이었고 물에 침 지한 후 메탄올에 추출한 약초,상초,특초의 함량은 각각 $113.23\;mg\%,\;81.46\;mg\%,\;72.78\;mg\%$이었다. 전자공여능은 BHT $0.02\%$ 첨가구보다 더 우수한 것은 물에 침 지한 후 메탄올로 추출한 특초의 1.5, 2.0, 2.5, 3.0$\%$ 첨가구와 상초와 약초의 각 1.0, 1.5, 2.0, 2.5, $3.0\%$ 첨가구 등 총 22개의 시료이 었다. 그리고 $\delta-tocopherol\;0.02\%$ 첨가구와 같거나 더 우수한 시료는 물에 침 지한 후 메탄을 추출한 상초 1.5, $2.0\%$와 약초 1.0, $1.5\%$등 총 8개의 시료이었다 산패유도기간은 대추 시료의 첨가 농도가 증가함에 따라 산패유도기간도 증가하였으며 BHT $0.02\%$ 첨가구보다 산패유도기간이 더 우수하거나 비슷한 시료는 물에 침지한 후 메탄올에 추출한 상초 1.5, 2.0$\%$와 약초 1.0, 1.5, $2.0\%$를 첨가한 것과 메탄을 추출물인 특초 $2.0\%$와 약초를 $2.0\%$첨가한 것이었다 대추의 항산화 효능은 물에 침 지한 후 메탄올 추출한 약초가 가장 우수하였으며 약초추출물의 동결건조 시료는 식품첨가물로 사용할 수 있는 가능성이 있다고 생각된다.

들깨 조직으로부터 callus 유기에 따른 지질 및 단백질 조성의 변화 (Changes of Protein and Lipid During Callus Induction and Plant Regeneration from Perilla frutescens)

  • 김현경;김도훈;정순재;남재성;정대수
    • 생명과학회지
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    • 제11권3호
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    • pp.254-258
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    • 2001
  • The biochemical change during regeneration of perilla callus were investigated by comparing total protein and lipid contents, protein band pattern in SDS-PAGE, and fatty acid composition in the calli cultured for various period(0, 1, 3, 5 and 6 weeks) Calli were induced from cotyledon and hypocotyl explants of peplants of perilla on perilla on MS medium containing BA(0.5 mg/L) and NAA(0.5mg/L). The protein contents reached the peak at 3 weeks after induction of calli, and then was decreased. Total lipid contents was decreased as the culture period increased. The band pattern of polypeptides showed that 30KD and 45KD polypeptides and 22KD and 45KD polypetides were major proteins in the cotyledon and hypocotyl explants, respectively. However increase of culture period only 30KD protein was highly accumulated.

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강재의 유도가열 방법의 수치적 승온 해석 (A Numerical Study on Temperature Profiles of Steel Plates Heated by Induction Heater)

  • 김형진;정원철;조병수
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2003년도 춘계학술대회
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    • pp.1412-1416
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    • 2003
  • Induction Heaters are commonly used in heating steel strip product, because it can rapidly and efficiently heat steel strip/bar. In this study, a inductive heating model is developed and the predictions are compared with measured temperatures. The temperatures are measured from POSCO thin-slab rolling facility (so called Minimill). Induction heater is installed between reduction unit and holding furnace This induction heater raise the temperature of steel bars from $930^{\circ}C$ to about $1100^{\circ}C$ which gives the required temperature for finishing mill process after holding period at holding furnace. Unlike other simple equation models, this model allows us to predict temperature profiles of sections of steel bars.

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Effects of Cold Pretreatment and Medium Composition on Anther Culture Initiation in Strawberry

  • Na, Hae-Young;Kim, Dae-Young;Chun, Chang-Hoo
    • 원예과학기술지
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    • 제29권5호
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    • pp.488-493
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    • 2011
  • Callus culture initiation of strawberry (Fragaria${\times}$ananassa Duch.) was investigated at different Murashige and Skoog (MS) medium strengths, types and concentrations of plant growth regulators, and incorporating a cold pretreatment period to determine the optimal nutritional and environmental conditions. No high quality callus was induced on MS media without auxin regardless of medium strength. When 6-benzylaminopurine (BA) was combined with indole acetic acid (IAA), naphthalene acetic acid (NAA), and 2,4-dichlorophenoxyacetic acid (2,4-D), high quality callus were highly induced compared to medium supplemented with auxin alone. When $0.5mg{\cdot}L^{-1}$ BA was combined with IAA, NAA, and 2,4-D, high quality callus induction was more effective than the medium supplemented with the other BA concentrations. The best combination of auxin and cytokinin for high quality callus induction was $1.0mg{\cdot}L^{-1}$ NAA and $0.5mg{\cdot}L^{-1}$ BA. Although the differences in callus induction were not significant, high quality callus induction at half strength MS medium was more effective than at full strength medium. When $30g{\cdot}L^{-1}$ sucrose was added to the half strength MS medium, the rate of high quality callus induction increased. The optimum cold pretreatment temperature and period for high quality callus induction were $4^{\circ}C$ and 72 h, respectively. Regeneration rate of high quality callus increased in MS medium supplemented with thidiazuron.

식물 추출물이 어유의 산화 안정성에 미치는 영향 (Study on Antioxidative Activity of Plant Extracts in Fish Oil)

  • 장지선;홍장환;이기택
    • 한국식품저장유통학회지
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    • 제13권6호
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    • pp.726-731
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    • 2006
  • 식물 추출물들의 어유에 대한 항산화력을 rancimart test, 과산화물가, TBA, DPPH 소거능을 이용하여 알아보고자 하였다. 44종 식물추출물을 1,000 ppm 첨가한 어유를 선 실험하여 대조구보다 induction period가 약 $1.5{\sim}3.1$배 증가된 결과를 보인 추출물 7종을 선별하여 주된 실험 시료로 사용하였다. 농도별(100, 200, 300, 500, 700, 1,000 ppm) rancimat test 결과 감자 추출물이 가장 연장된 induction period를 보였으며 붉나무는 첨가량에 따른 높은 증가율을 보였다. 과산화물가와 IBA에서 감자와 붉나무의 항산화력이 보였으며, DPPH 소거능에서는 붉나무의 활성이 높게 나타났다.

Effect of IPTG Induction on Production of ${\beta}$-Galactosidase-PreS2 Fusion Protein in Recombinant Escherichia coli

  • Nam, Soo-Man;Park, Young-Hoon
    • Journal of Microbiology and Biotechnology
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    • 제1권4호
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    • pp.274-280
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    • 1991
  • Effects of IPTG induction on cell growth and production of ${\beta}$-galactosidase-preS2 fusion protein (${\beta}$gal-preS2) were studied in a defined medium using a recombinant Escherichia coli JM109/pCMHB30. IPTG was added (0.2 mM) to induce the cloned-gene expression in the early-, mid-, and late-log growth phases. The most serious decreases in growth rate and plasmid stability were observed for the induction in the early-log growth phase. The expression level of ${\beta}$gal-preS2 attained by the induction in the mid-log phase was about 0.51 mg fusion protein/mg total cellular protein, which was 2- and 5-fold improvement over the levels obtained with the inductions in the early- and late-log phases. Formation of acidic byproducts including acetate and pyruvate showed different profiles during the fermentation period for each cases of induction; pyruvate was the major byproduct for the induction in the early-log phase while acetate production became more significant for the cases of inductions in the mid- and late-log phases.

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Enhanced Performance of Induction Cookers by the Use of Polymer Composites

  • Nam, Yoon-Jae;Lee, Dong-Ki;Kwon, Jong-Han;Shin, K.H.;Lim, S.H.
    • Journal of Magnetics
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    • 제15권3호
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    • pp.123-127
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    • 2010
  • The use of a cooling fan in an induction cooker raises a reliability issue due to the attraction of dust causing a malfunction of the cooling fan and also increases the noise level and power consumption of the device. The purpose of this study is to attempt to solve these problems by molding the Cu coil of an induction cooker with polymer composites that have a low electrical conductivity but a high thermal conductivity. Among the several polymer composites tested in this study, an aluminum nitride-based composite showed the best performance. The results show that the new induction cooker with the molded composite can operate for an extended period of time without the use of a cooling fan. A further advantage of this new type of induction cooker is that the temperature of the substance in the cooking pot increases more rapidly, indicating an increased efficiency of the induction cooker.

피하신경전기자극이 STZ-유도 당뇨 쥐의 척수신경원 흥분성에 미치는 효과 (Effect of Percutaneous Electrical Nerve Stimulation on the Spinal Neuron Excitability in STZ-induced Diabetic Rats.)

  • 김양호;정진규;김태열
    • 대한임상전기생리학회지
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    • 제2권2호
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    • pp.13-23
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    • 2004
  • This study aimed at examining the effects of percutaneous electrical nerve stimulation(PENS) applied to different parts of the streptozotocin(STZ) induced diabetic rats on the change of glucose level and spinal neuron excitability. A total of twenty-eight SD rats, divided into four groups, were used as experiment animal. Experiment group I, the normal control group, was composed of normal rats without diabetes induction. Experiment group was composed II of the rats without any treatment after experimental diabetes induction. Experiment group III was composed of the rats with 2 Hz and $200\;{\mu}s$ of PENS to the acupuncture points related with diabetes for 20 minutes after diabetes induction. Experiment group IV was composed of the rats with 2 Hz and $200\;{\mu}s$ of PENS to the parts unrelated with diabetes for 20 minutes after diabetes induction. The results can be summarized as follow: As for glucose level, the group I showed no change within normal range, and the group III showed significant increase, compared with other groups (p<0.05). As for the change of H latency, M and H amplitude, the group III showed significant differences in decrease of latency and amplitude (p<0.05). As for Hmax/Mmax ratio, the normal and other groups showed no significant differences in decrease of amplitude. It can be concluded from the above results that PENS to the acupuncture points of the STZ-induced diabetic rats was effective for spinal neurone excitability, in particular, for those of the group with PENS to the acupuncture points. This study was conducted in the period of acute diabetes induction, and therefore, further study should be conducted in the period of chronic diabetes to research both acute and chronic diabetes.

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