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Controlling Factors of Feed Intake and Salivary Secretion in Goats Fed on Dry Forage

  • Sunagawa, K.;Ooshiro, T.;Nakamura, N.;Nagamine, I.;Shiroma, S.;Shinjo, A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.10
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    • pp.1414-1420
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    • 2005
  • The purpose of this research was to determine whether or not feeding induced hypovolemia (decreases in plasma volume) and decreases in plasma bicarbonate concentration caused by loss of $NaHCO_3$ from the blood, act to suppress feed intake and saliva secretion volumes during the initial stages of feeding in goats fed on dry forage. The animals were fed twice a day at 10:30 and at 16:00 for 2 h each time. Prior to the morning feeding, the collected saliva (3-5 kg) was infused into the rumen. During the morning 2 h feeding period (10:30 to 12:30), the animals were fed 2-3 kg of roughly crushed alfalfa hay cubes. At 16:00, the animals were fed again with 0.8 kg of alfalfa hay cubes, 200 g of commercial ground concentrate and 20 g of sodium bicarbonate. In order to compensate for water or $NaHCO_3$ lost through saliva during initial stages of feeding, a 3 h intravenous infusion (17-19 ml/min) of artificial mixed saliva (ASI) or mannitol solution (MI) was begun 1 h prior to the morning feeding and continued until the conclusion of the 2 h feeding period. The physiological state of the goats in the present experiment remained unchanged after parotid gland fistulation. Circulating plasma volume decreases caused by feeding (estimated by increases in plasma total protein concentration) were significantly suppressed by the ASI and MI treatments. During the first 1 h of the 2 h feeding period, plasma osmolality in the ASI treatment was the same as the NI (non-infusion control) treatment, while plasma osmolality in the MI treatment was significantly higher. In comparison to the NI treatment, cumulative feed intake levels for the duration of the 2 h feeding period in the ASI and MI treatments increased markedly by 56.6 and 88.3%, respectively. On the other hand, unilateral cumulative parotid saliva secretion volume following the termination of the 2 h feeding period in the ASI treatment was 50.7% higher than that in the NI treatment. MI treatment showed the same level as the NI treatment. The results of the present experiment proved that the humoral factors involved in the suppression of feeding and saliva secretion during the initial stages of feeding in goats fed on dry forage, are feeding induced hypovolemia and decrease in plasma $HCO_3^-$ concentration caused by loss of $NaHCO_3$ from the blood.

Analysis on optical pulse propagation in atomic medium for amplification without inversion (밀도 반전 없는 증폭 매질에서 광펄스 군속도의 제어 과정 분석)

  • Kim, Haeng-Hwa;Kim, Kyung-Dae;Lee, Rim;An, Moon-Hee;Kim, Joong-Bok
    • Korean Journal of Optics and Photonics
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    • v.14 no.5
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    • pp.483-490
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    • 2003
  • We have analyzed theoretically optical pulse propagation in a coherent atomic medium for amplification without inversion (AWI), which is achieved by adding incoherent optical pumping to a typical EIT system. In order to explain experimental results [Kim et al., J. Phys. B, 36, 2671(2003)] to control the group velocity of the optical pulse by changing pumping power, we established a 5-level atomic system and applied density matrix equations. This AWI model system is different from previous AWI systems from the viewpoint of using two levels for incoherent optical pumping isolated optically from the EIT (electromagentically induced transparency) system so that more atoms can participate in pulse speed control. We have found that population transfer by collisions between ground states plays a decisive role for efficient AWI, and more atoms are effective for slowing the pulse. Our numerical results are in good agreement qualitatively with experimental results.

Effect of Parotid Saliva Secretion on Dry Forage Intake in Goats

  • Sunagawa, Katsunori;Nakatsu, Yoshifumi;Nishikubo, Yoriko;Ooshiro, Takeshi;Naitou, Kouta;Nagamine, Itsuki
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.8
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    • pp.1118-1125
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    • 2003
  • Research was carried out to clarify whether a suppression of dry forage intake during the early stages of feeding in ruminants is caused by feeding induced hypovolemia which is produced by the accelerated secretion of parotid saliva. Goats with a parotid fistula were fed roughly crushed alfalfa hay cubes, commercial ground concentrate feed and $NaHCO_3$ twice daily (10:00-12:00, 16:00-18:00). The animals were free access to drinking water all day prior to, during and after experiments. The animals were intraruminally infused every day prior to the morning feeding period with parotid saliva collected from the parotid fistula over a 24 h period. The present experiment consisted of two treatments, non-infusion (RNI) and intraruminal infusion of parotid saliva (RSF). In the RSF treatment, 4-5 kg of parotid saliva (280-290 mOsm/l) collected over a 24 h period was intraruminally infused 1 h prior to the commencement of the morning feeding. During feeding, eating and parotid saliva secretion rates were measured. Blood samples were also periodically collected from the jugular vein. During and after 2 h feeding, water intakes were measured, respectively. These measurements were used to define thirst levels. It is thought that rumen fill in the RSF treatment was higher than the RNI treatment. Plasma osmolality in the RSF treatment increased in the first half of the 2 h feeding period due to the intraruminal infusion of parotid saliva. Therefore, parotid saliva secretion rates in the RSF treatment were lower than the RNI treatment for 30 min period from 30 to 60 min after the commencement of feeding. On the other hand, plasma total protein concentration and hematocrit in the RSF treatment decreased by 3.2 and 3.3% prior to the commencement of feeding due to the intraruminal infusion of parotid saliva. In the first half of the 2 h feeding period, plasma total protein concentration and hematocrit in the RSF treatment showed a tendency to decrease compared to the RNI treatment. Thirst level in the RSF treatment during feeding was approximately 31.3% less than the RNI treatment. Upon the completion of the 2 h feeding period, cumulative feed intake in the RSF treatment was significantly larger (19.7%) than the RNI treatment. The results suggest that a suppression of dry forage intake during the early stages of feeding in goats is partly caused by feeding induced hypovolemia, which is produced by the accelerated secretion of parotid saliva.

Suggestion for a New Grading Scale for Radiation Induced Pneumonitis Based on Radiological Findings of Computerized Tomography: Correlation with Clinical and Radiotherapeutic Parameters in Lung Cancer Patients

  • Kouloulias, Vassilios;Zygogianni, Anna;Efstathopoulos, Efstathios;Victoria, Oikonomopoulou;Christos, Antypas;Pantelis, Karaiskos;Koutoulidis, Vassilios;Kouvaris, John;Sandilos, Panagiotis;Varela, Maria;Aytas, Ilknur;Gouliamos, Athanasios;Kelekis, Nikolaos
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.2717-2722
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    • 2013
  • Background: The objective of this research is the computed axial tomography (CT) imaging grading of radiation induced pneumonitis (RP) and its correlation with clinical and radiotherapeutic parameters. Materials and Methods: The chest CT films of 20 patients with non-small cell lung cancer who have undergone threedimensional conformal radiation therapy were reviewed. The proposed CT grading of RP is supported on solely radiological diagnosis criteria and distinguishes five grades. The manifestation of RP was also correlated with any positive pre-existing chronic obstructive pulmonary disease (COPD) history, smoking history, the FEV1 value, and the dosimetric variable V20. Results: The CT grading of RP was as follows: 3 patients (15%) presented with ground glass opacity (grade 1), 9 patients (45%) were classified as grade 2, 7 patients (35%) presented with focal consolidation, with or without elements of fibrosis (grade 3), and only one patient (5%) presented with opacity with accompanying atelectasis and loss of pulmonary volume (grade 4). Both univariate and multivariate analysis revealed as prognostic factors for the radiological grading of RP the reduction of FEV1 and the V20 (P=0.026 and P=0.003, respectively). There was also a significant (P<0.001) correlation of radiological grading of RP with FEV1 and V20 (spearman rho 0.92 and 0.93, respectively). Conclusions: The high correlation of the proposed radiological grading with the FEV1 and the V20 is giving a satisfactory clinical validity. Although the proposed grading scale seems relevant to clinical practice, further studies are needed for the confirmation of its validity and reliability.

Application and Performance Evaluation of Helicopter Active Vibration Control System for Surion (헬리콥터 능동진동제어시스템의 수리온 적용 및 성능 분석)

  • Kim, Do-Hyung;Kim, Tae-Joo;Paek, Seung-Kil;Kwak, Dong-Il;Jung, Se-Un
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.43 no.6
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    • pp.557-567
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    • 2015
  • The most decisive factor of major sources of a helicopter is the main rotor system and the rotor-induced vibration is one of the technical challenges which should be resolved to ensure comfort for crews and passengers. Passive vibration reduction devices are adopted in conventional helicopters and several types of passive devices are also used in Surion. In recent years, foreign helicopter manufactures have increasingly applied the application of AVCS (active vibration control system) because of their superior performance with lower weight compared to passive device. In addition to weight reduction, AVCS has advantages maintaining its performance over aircraft configuration changes and flight condition changes. The technology demonstration program was performed in order to validate the performance of AVCS when applied to Surion, and optimization process for finding optimal configuration of sensors and actuators. Optimal configuration was produced using ground and flight test data, and its performance was evaluated and compared with flight test result.

A Case of Acute Respiratory Distress Syndrome with Pulmonary Embolism Induced by Injection of Silicone at Vaginal Wall (질벽의 실리콘 액 주사에 의한 폐색전종 및 급성 호흡곤란 증후군 1예)

  • Kang, Moon-Bo;Kim, Seong-Tae;Lee, Jung-Gu;Seo, Chan-Jong;Lee, Hwa-Eun;Jeong, Jung-Bae;Kim, Sung-Gwon;Kim, Chul;Park, Jeong-Woong;Jeong, Seong-Whan;Nam, Gui-Hyun
    • Tuberculosis and Respiratory Diseases
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    • v.46 no.3
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    • pp.414-419
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    • 1999
  • Silicone fluid(polydimethylsiloxane) is widely used in breast augmentation and other cosmetic procedures because of little incidence of complications and low mortality rate. However, local reaction following silicone injections can be occurred sometimes leading to serious complications. Especially, illicit silicone injections have resulted in severe reactions within the pulmonary area, and some have resulted in acute respiratory distress syndrome subsequently. We experienced a case of acute respiratory distress syndrome induced by subcutaneous injections of silicone at vaginal wall. The patients was 39-year-old, previously healthy woman who had complained of dyspnea related to silicone injection at vaginal wall. Chest X-ray and chest CT scan show diffuse air consolidation with ground glass opacities and perfusion lung scan revealed likelihood of pulmonary embolism as showing multiple perfusion defects. We report a case of acute respiratory distress syndrome occured after silicone injection with review of literature.

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Analysis on the characteristics of the earth pressure distribution induced by the integrated steel pipe-roof construction (일체형 강관 파이프루프 시공에 따른 주변 지반의 토압 분포 특성 분석)

  • Sim, Youngjong;Jin, Kyu-Nam;Song, Ki-Il
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.15 no.5
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    • pp.455-468
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    • 2013
  • In recent, various types of steel pipe-roof methods, which is reinforced by mortar after propulsion of steel pipe into the ground, have been used for the construction of trenchless underpass. Integrated steel pipe-roof has flexural stiffness and can resist against overburden load and reduce the stress acting on the concrete underpass structures. Due to arching effect, vertical and horizontal stress distribution around the steel pipe-roof is changing. In this study, therefore, the characteristic of stress distribution around the underpass induced by the construction of integrated steel pipe-roof is investigated by using numerical method. To examine the soil-structure interaction, interface element is introduced. Results show that vertical stress acting on the concrete structure placing inside the steel pipe-roof is significantly reduced due to arching effect and flexural stiffness of integrated steel pipe-roof. Design load can be reduced and effective design of underpass will be available if the earth pressure reduction due to arching effect is considered in the design stage.

Propagation characteristics of blast-induced vibration to fractured zone (파쇄영역에 따른 발파진동 전파특성)

  • Ahn, Jae-Kwang;Park, Duhee;Park, Ki-Chun;Yoon, Ji Nam
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.19 no.6
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    • pp.959-972
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    • 2017
  • In evaluation of blast-induced vibration, peak particle velocity (PPV) is generally calculated by using attenuation relation curve. Calculated velocity is compared with the value in legal requirements or the standards to determine the stability. Attenuation relation curve varies depending on frequency of test blasting, geological structure of the site and blasting condition, so it is difficult to predict accurately using such an equation. Since PPV is response value from the ground, direct evaluation of the structure is impractical. Because of such a limit, engineers tend to use the commercial numerical analysis program in evaluating the stability of the structure more accurately. However, when simulate the explosion process using existing numerical analysis program, it's never easy to accurately simulate the complex conditions (fracture, crushing, cracks and plastic deformation) around blasting hole. For simulating such a process, the range for modelling will be limited due to the maximum node count and it requires extended calculation time as well. Thus, this study is intended to simulate the elastic energy after fractured zone only, instead of simulating the complex conditions of the rock that results from the blast, and the analysis of response characteristics of the velocity depending on shape and size of the fractured zone was conducted. As a result, difference in velocity and attenuation character were calculated depending on fractured zone around the blast source appeared. Propagation of vibration tended to spread spherically as it is distanced farther from the blast source.

A Study on the Skin Characteristics of Qi Deficiency and Blood Deficiency Animal Model (기허(氣虛), 혈허(血虛) 동물모형(動物模型)의 일반(一般) 특성(特性) 및 피부(皮膚) 특성(特性) 연구(硏究))

  • Shin, Yoon-Jin;Kim, Yoon-Bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.22 no.1
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    • pp.76-88
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    • 2009
  • Back ground and Objective : There is a need for objectification and scientific verification of Pattern identification in Oriental medicine. The purpose of this study was to investigate the skin characteristics of Qi deficiency and Blood deficiency animal models. Material and Methods : Sprague-Dawley rats were divided into three groups: normal group, Qi deficiency group and Blood deficiency group. The Qi deficiency animal model was induced through restriction of food (75g/kg/day) for 20 days. Blood deficiency animal model was induced by bleeding from tail vein(0.3 ml/time) 8 times. The normal animal model was kept without any intervention. The general condition was observed by measuring body weight, body temperature, blood pressure, pulse rate, and hematological and biochemical parameters. The skin characteristics were observed by measuring the erythema index(EI), melanin index(Ml), transepidermal water loss(TEWL) and dermal microcirculation. Results : 1. In the Qi deficiency group, body weight was lower than the other groups. In the Qi deficiency group, blood pressure was lower than in the Normal group. There was no difference in body temperature and pulse rate between the three groups. 2. In the Qi deficiency group, blood sugar was lower than in the Blood deficiency group. There was no difference in triacylglycerol between the three groups. In the Qi deficiency group, the WBC count was lower than in the Blood deficiency group. RBC count was highest in the Qi deficiency group, Normal group and Blood deficiency group respectively. In the Qi deficiency group, Hb and Hct were higher than the other groups. 3. EI and MI were decreased in the Qi deficiency group, and EI showed a significant decrease. 4. EI and MI were increased in the Blood deficiency group, and MI showed a significant increase. 5. TEWL was significantly increased in the Qi deficiency group, while it was decreased in the Blood deficiency group, TEWL was highest in the Qi deficiency group, Normal group and Blood deficiency group respectively and all three groups showed significant difference. 6. In the Qi deficiency group, dermal microcirculation was lower than the other groups. Conclusion : The above results show that the erythema index decreases in the Qi deficiency model, and the melanin index increases in the Blood deficiency model. The Qi deficiency animal model shows an increase in transepidermal water loss, while the Blood deficiency animal model shows a decrease. Further studies should develop new models of Pattern Identification that are more specific.

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Two-dimensional Numerical Simulation of Rainfall-induced Slope Failure (강우에 의한 사면붕괴에 관한 2차원 수치모의)

  • Regmi, Ram Krishna;Jung, Kwan-Sue;Lee, Gi-Ha
    • Proceedings of the Korea Water Resources Association Conference
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    • 2012.05a
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    • pp.34-34
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    • 2012
  • Heavy storms rainfall has caused many landslides and slope failures especially in the mountainous area of the world. Landslides and slope failures are common geologic hazards and posed serious threats and globally cause billions in monetary losses and thousands of casualies each year so that studies on slope stability and its failure mechanism under rainfall are being increasing attention of these days. Rainfall-induced slope failures are generally caused by the rise in ground water level, and increase in pore water pressures and seepage forces during periods of intense rainfall. The effective stress in the soil will be decreased due to the increased pore pressure, which thus reduces the soil shear strength, eventually resulting in slope failure. During the rainfall, a wetting front goes downward into the slope, resulting in a gradual increase of the water content and a decrease of the negative pore-water pressure. This negative pore-water pressure is referred to as matric suction when referenced to the pore air pressure that contributes to the stability of unsaturated soil slopes. Therefore, the importance is the study of saturated unsaturated soil behaviors in evaluation of slope stability under heavy rainfall condition. In an actual field, a series of failures may occur in a slope due to a rainfall event. So, this study attempts to develop a numerical model to investigate this failure mechanism. A two-dimensional seepage flow model coupled with a one-dimensional surface flow and erosion/deposition model is used for seepage analysis. It is necessary to identify either there is surface runoff produced or not in a soil slope during a rainfall event, while analyzing the seepage and stability of such slopes. Runoff produced by rainfall may result erosion/deposition process on the surface of the slope. The depth of runoff has vital role in the seepage process within the soil domain so that surface flow and erosion/deposition model computes the surface water head of the runoff produced by the rainfall, and erosion/deposition on the surface of the model slope. Pore water pressure and moisture content data obtained by the seepage flow model are then used to analyze the stability of the slope. Spencer method of slope stability analysis is incorporated into dynamic programming to locate the critical slip surface of a general slope.

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